IL91638A - Synergistic pharmaceutical compositions containing2,6-dialkyl-3-(esterified carboxyl) 1,4-dihydro-4-phenyl-5-pyridylcarboxylic acid esters of 1,4:3,6-dianhydrohexitols and glyceryl or isosorbide nitrates - Google Patents
Synergistic pharmaceutical compositions containing2,6-dialkyl-3-(esterified carboxyl) 1,4-dihydro-4-phenyl-5-pyridylcarboxylic acid esters of 1,4:3,6-dianhydrohexitols and glyceryl or isosorbide nitratesInfo
- Publication number
- IL91638A IL91638A IL9163889A IL9163889A IL91638A IL 91638 A IL91638 A IL 91638A IL 9163889 A IL9163889 A IL 9163889A IL 9163889 A IL9163889 A IL 9163889A IL 91638 A IL91638 A IL 91638A
- Authority
- IL
- Israel
- Prior art keywords
- ism
- gmn
- compound
- general formula
- gtn
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3831949A DE3831949A1 (de) | 1988-09-20 | 1988-09-20 | Arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL91638A0 IL91638A0 (en) | 1990-04-29 |
| IL91638A true IL91638A (en) | 1994-05-30 |
Family
ID=6363342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL9163889A IL91638A (en) | 1988-09-20 | 1989-09-14 | Synergistic pharmaceutical compositions containing2,6-dialkyl-3-(esterified carboxyl) 1,4-dihydro-4-phenyl-5-pyridylcarboxylic acid esters of 1,4:3,6-dianhydrohexitols and glyceryl or isosorbide nitrates |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5254570A (de) |
| EP (1) | EP0361156B1 (de) |
| JP (1) | JPH0643307B2 (de) |
| KR (1) | KR900004743A (de) |
| AT (1) | ATE86487T1 (de) |
| CA (1) | CA1331568C (de) |
| DD (1) | DD284601A5 (de) |
| DE (2) | DE3831949A1 (de) |
| DK (1) | DK461089A (de) |
| ES (1) | ES2053892T3 (de) |
| FI (1) | FI894424L (de) |
| HU (1) | HUT52384A (de) |
| IE (1) | IE892992L (de) |
| IL (1) | IL91638A (de) |
| PT (1) | PT91736B (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8003811B2 (en) | 2008-02-07 | 2011-08-23 | Nicox S.A. | Nitric oxide donor compounds |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2454807A1 (fr) * | 1979-04-25 | 1980-11-21 | Laleuf Sa Expl Laboratoires | Nouveau medicament constitue par l'association de dinitrate d'isosorbide et de trinitroglycerine |
| DE3248548A1 (de) * | 1982-12-29 | 1984-07-05 | Heinrich Mack Nachf., 7918 Illertissen | Acylderivate von 1,4:3,6-dianhydro-hexiten, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3523544A1 (de) * | 1985-07-02 | 1987-01-15 | Bayer Ag | Nifedipin kombinationspraeparat |
| DE3523540A1 (de) * | 1985-07-02 | 1987-01-15 | Bayer Ag | Dihydropyridin kombinationspraeparat |
-
1988
- 1988-09-20 DE DE3831949A patent/DE3831949A1/de not_active Withdrawn
-
1989
- 1989-09-06 EP EP89116468A patent/EP0361156B1/de not_active Expired - Lifetime
- 1989-09-06 ES ES89116468T patent/ES2053892T3/es not_active Expired - Lifetime
- 1989-09-06 AT AT89116468T patent/ATE86487T1/de not_active IP Right Cessation
- 1989-09-06 DE DE8989116468T patent/DE68905278T2/de not_active Expired - Fee Related
- 1989-09-14 IL IL9163889A patent/IL91638A/en not_active IP Right Cessation
- 1989-09-18 CA CA000611721A patent/CA1331568C/en not_active Expired - Fee Related
- 1989-09-18 PT PT91736A patent/PT91736B/pt not_active IP Right Cessation
- 1989-09-18 JP JP1241658A patent/JPH0643307B2/ja not_active Expired - Lifetime
- 1989-09-19 IE IE892992A patent/IE892992L/xx unknown
- 1989-09-19 DK DK461089A patent/DK461089A/da not_active Application Discontinuation
- 1989-09-19 DD DD89332807A patent/DD284601A5/de not_active IP Right Cessation
- 1989-09-19 HU HU894876A patent/HUT52384A/hu unknown
- 1989-09-19 KR KR1019890013431A patent/KR900004743A/ko not_active Ceased
- 1989-09-19 FI FI894424A patent/FI894424L/fi not_active Application Discontinuation
- 1989-09-20 US US07/411,345 patent/US5254570A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE68905278T2 (de) | 1993-06-17 |
| ATE86487T1 (de) | 1993-03-15 |
| US5254570A (en) | 1993-10-19 |
| JPH0643307B2 (ja) | 1994-06-08 |
| PT91736A (pt) | 1990-03-30 |
| FI894424A7 (fi) | 1990-03-21 |
| HUT52384A (en) | 1990-07-28 |
| KR900004743A (ko) | 1990-04-12 |
| CA1331568C (en) | 1994-08-23 |
| PT91736B (pt) | 1995-05-31 |
| EP0361156A3 (en) | 1990-04-18 |
| EP0361156B1 (de) | 1993-03-10 |
| DD284601A5 (de) | 1990-11-21 |
| FI894424L (fi) | 1990-03-21 |
| DE68905278D1 (de) | 1993-04-15 |
| IL91638A0 (en) | 1990-04-29 |
| EP0361156A2 (de) | 1990-04-04 |
| DK461089A (da) | 1990-03-21 |
| FI894424A0 (fi) | 1989-09-19 |
| JPH02160790A (ja) | 1990-06-20 |
| IE892992L (en) | 1990-03-20 |
| ES2053892T3 (es) | 1994-08-01 |
| DE3831949A1 (de) | 1990-03-22 |
| DK461089D0 (da) | 1989-09-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |