IL90790A - Polypeptides and synthetic lung surfactant preparation comprising polypeptides and lipids - Google Patents

Polypeptides and synthetic lung surfactant preparation comprising polypeptides and lipids

Info

Publication number
IL90790A
IL90790A IL9079089A IL9079089A IL90790A IL 90790 A IL90790 A IL 90790A IL 9079089 A IL9079089 A IL 9079089A IL 9079089 A IL9079089 A IL 9079089A IL 90790 A IL90790 A IL 90790A
Authority
IL
Israel
Prior art keywords
leu
lys
glu
polypeptide
ser
Prior art date
Application number
IL9079089A
Other languages
English (en)
Other versions
IL90790A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL90790A0 publication Critical patent/IL90790A0/xx
Publication of IL90790A publication Critical patent/IL90790A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IL9079089A 1988-07-01 1989-06-29 Polypeptides and synthetic lung surfactant preparation comprising polypeptides and lipids IL90790A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21422888A 1988-07-01 1988-07-01
US28279588A 1988-12-09 1988-12-09

Publications (2)

Publication Number Publication Date
IL90790A0 IL90790A0 (en) 1990-01-18
IL90790A true IL90790A (en) 1996-10-31

Family

ID=26908797

Family Applications (1)

Application Number Title Priority Date Filing Date
IL9079089A IL90790A (en) 1988-07-01 1989-06-29 Polypeptides and synthetic lung surfactant preparation comprising polypeptides and lipids

Country Status (13)

Country Link
EP (1) EP0348967A3 (de)
JP (1) JPH0253798A (de)
KR (1) KR900001719A (de)
CN (1) CN1037350C (de)
AR (1) AR245141A1 (de)
AU (1) AU617827B2 (de)
DK (1) DK326889A (de)
FI (1) FI95914C (de)
HU (1) HU204288B (de)
IL (1) IL90790A (de)
NO (1) NO301236B1 (de)
NZ (1) NZ229737A (de)
PT (1) PT91027B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260273A (en) * 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
EP0458167B1 (de) * 1990-05-21 1997-04-23 Abbott Laboratories Fettsäure-Oberflächenaktives-Lungenprotein Konjate
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
WO1994003485A1 (en) * 1992-07-29 1994-02-17 Merrell Dow Pharmaceuticals Inc. Peptide lung surfactants and therapeutic combinations
ATE157671T1 (de) * 1992-07-31 1997-09-15 Merrell Pharma Inc Synthetische peptide als lungensurfactants mit kovalent gebundenen antioxidantien
RU2144925C1 (ru) * 1993-12-08 2000-01-27 ТТ Фармасьютикалс, Инк. Новые синтетические пептиды, легочная поверхностно-активная композиция, лекарственный препарат для лечения респираторного дистресс-синдрома
GB9524007D0 (en) * 1995-11-23 1996-01-24 Bangham Alec D Endotrachael tubes with pulmonary medicaments
CA2384861A1 (en) 1999-09-16 2001-03-22 Byk Gulden Lomberg Chemische Fabrik Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
CN1558927A (zh) 2001-09-25 2004-12-29 ����ɭ���ڻ�ѧר����˾ 增塑聚氯乙烯
US6982075B2 (en) 2001-10-11 2006-01-03 Altana Pharma Ag Use of pulmonary surfactant
JP5108515B2 (ja) 2004-08-06 2012-12-26 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺サーファクタント及びｔｎｆ由来ペプチドを含有する組成物
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
CA2744940A1 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
CN111568853B (zh) * 2020-04-30 2023-07-28 杭州濡湜生物科技有限公司 一种新型肺部智能释药系统

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705684A (en) * 1985-05-31 1987-11-10 The University Of Tennessee Research Corporation Synthetic M proteins - streptococci type 6

Also Published As

Publication number Publication date
FI95914C (fi) 1996-04-10
AU3722789A (en) 1990-01-04
FI893214A0 (fi) 1989-06-30
HUT50848A (en) 1990-03-28
EP0348967A2 (de) 1990-01-03
KR900001719A (ko) 1990-02-27
NO892733L (no) 1990-01-02
AR245141A1 (es) 1993-12-30
NZ229737A (en) 1991-05-28
NO892733D0 (no) 1989-06-30
HU204288B (en) 1991-12-30
PT91027A (pt) 1990-02-08
FI893214A7 (fi) 1990-01-02
AU617827B2 (en) 1991-12-05
CN1039029A (zh) 1990-01-24
CN1037350C (zh) 1998-02-11
PT91027B (pt) 1995-03-31
EP0348967A3 (de) 1990-09-12
JPH0253798A (ja) 1990-02-22
DK326889A (da) 1990-01-02
DK326889D0 (da) 1989-06-30
NO301236B1 (no) 1997-09-29
FI95914B (fi) 1995-12-29
IL90790A0 (en) 1990-01-18

Similar Documents

Publication Publication Date Title
US4861756A (en) Synthetic pulmonary surfactant
EP0666754B1 (de) Synthetische, oberflächen aktive zusammensetzung für die lunge mit antioxidativen eigenschaften
AU617827B2 (en) Synthetic lung surfactant preparation comprising lipids and polypeptides
EP0383837B1 (de) Alveolare oberflächenaktive proteine
EP0538273A1 (de) Alveolares oberflächenaktives protein
EP0652894B1 (de) Synthetische peptide als lungensurfactants mit kovalent gebundenen antioxidantien
EP0656902B1 (de) Peptide als lungensurfactant und therapeutisch wirksame mischungen
US5169761A (en) Dna encoding and expression systems for alveolar surfactant proteins
CA2137349C (en) Peptide lung surfactants and therapeutic combinations
HK1008744A1 (en) Alveolar surfactant proteins
HK1008744B (en) Alveolar surfactant proteins
HK1185274A1 (en) Reconstituted surfactants having improved properties
HK1185274B (en) Reconstituted surfactants having improved properties

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
RH1 Patent not in force
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.