DE69125750D1 - Fettsäure-Oberflächenaktives-Lungenprotein Konjate - Google Patents

Fettsäure-Oberflächenaktives-Lungenprotein Konjate

Info

Publication number
DE69125750D1
DE69125750D1 DE69125750T DE69125750T DE69125750D1 DE 69125750 D1 DE69125750 D1 DE 69125750D1 DE 69125750 T DE69125750 T DE 69125750T DE 69125750 T DE69125750 T DE 69125750T DE 69125750 D1 DE69125750 D1 DE 69125750D1
Authority
DE
Germany
Prior art keywords
conjate
fatty acid
acid surfactant
lung protein
surfactant lung
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69125750T
Other languages
English (en)
Inventor
Virender Kumar Sarin
Shanker Lal Gupta
Darryl Robin Absolom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69125750D1 publication Critical patent/DE69125750D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69125750T 1990-05-21 1991-05-14 Fettsäure-Oberflächenaktives-Lungenprotein Konjate Expired - Lifetime DE69125750D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52558190A 1990-05-21 1990-05-21

Publications (1)

Publication Number Publication Date
DE69125750D1 true DE69125750D1 (de) 1997-05-28

Family

ID=24093832

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69125750T Expired - Lifetime DE69125750D1 (de) 1990-05-21 1991-05-14 Fettsäure-Oberflächenaktives-Lungenprotein Konjate

Country Status (4)

Country Link
US (2) US6022955A (de)
EP (1) EP0458167B1 (de)
CA (1) CA2042635A1 (de)
DE (1) DE69125750D1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
DE69332654T2 (de) * 1992-04-10 2003-09-25 Abbott Lab Fragmente eines oberflächenaktiven lungenproteins
FR2739860B1 (fr) * 1995-10-17 1998-01-02 Coletica Complexes amphiphiles, procede pour leur preparation et compositions en renfermant
US5958902A (en) * 1997-04-16 1999-09-28 Wisconsin Alumni Research Foundation Method and composition for treating sleep apnea
PT1192184E (pt) 1999-06-17 2007-03-30 Altana Pharma Ag Ésteres de proteína c surfactantes
JP2003523348A (ja) * 2000-02-16 2003-08-05 ノースウェスタン ユニバーシティ ポリペプトイド肺サーファクタント
US7004899B2 (en) * 2001-06-29 2006-02-28 Ethicon, Inc. System and method for assessing urinary function
WO2003001974A2 (en) * 2001-06-29 2003-01-09 Ethicon, Inc. A system and method for assessing urinary function
US7125568B2 (en) * 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
WO2005063792A2 (en) * 2003-12-31 2005-07-14 F. Hoffmann-La Roche Ag Methods for recovering cleaved peptide from a support
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
ES2380046T3 (es) 2005-01-06 2012-05-08 Discovery Laboratories, Inc. Régimen para el tratamiento con tensioactivos para tratar o prevenir la displasia broncopulmonar
CA2663795A1 (en) * 2006-09-19 2008-03-27 Discovery Laboratories, Inc. Pulmonary surfactant formulations and methods for promoting mucus clearance
KR20100020511A (ko) * 2007-06-05 2010-02-22 파카 풀머네리 파마슈티칼즈, 인크. 폐로의 약물 전달을 위한 조성물, 이의 용도
CA2744940A1 (en) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
CN102781236B (zh) * 2009-12-31 2015-01-07 凯姆制药公司 喹硫平的氨基酸缀合物、其制备和使用方法
RS58335B1 (sr) * 2010-03-11 2019-03-29 Kempharm Inc Konjugati kvetiapina sa masnom kiselinom, proces za njihovo dobijanje i njihova primena
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234475A (en) * 1975-08-15 1980-11-18 The Gillette Company Reacting protein with organic acid
US4406833A (en) * 1982-06-04 1983-09-27 Fats And Proteins Research Foundation, Inc. Surfactants derived from fatty acid esters and proteinaceous material
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
WO1987002037A1 (en) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Pulmonary surfactant proteins
US4918161A (en) * 1985-09-26 1990-04-17 Genetics Institute, Inc. Low molecular weight pulmonary surfactant proteins
US4882422A (en) * 1985-10-24 1989-11-21 Genetics Institute, Inc. Pulmonary surfactant proteins
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
EP0273916A4 (de) * 1986-05-06 1989-11-30 Childrens Hosp Medical Center Lungenhydrophobes, an ein oberflächenaktives mittel assoziiertes protein von 6000 dalton molekulargewicht sowie multimere davon.
EP0290516A4 (de) * 1986-10-24 1989-11-14 Jeffrey A Whitsett Proteine, die mit oberflächenwirksamen hydrophoben lungenwirkstoffen verbunden sind.
US4861756A (en) * 1988-03-08 1989-08-29 Merrell Dow Pharmaceuticals Inc. Synthetic pulmonary surfactant
AU3073789A (en) * 1988-03-31 1989-10-05 Abbott Laboratories Drug delivery using pulmonary surfactant to facilitate absorption
AR245141A1 (es) * 1988-07-01 1993-12-30 Merrell Dow Pharma Procedimiento de sintesis secuencial o de bloques en fase solida para preparar polipeptidos de estructura helicoidal.
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE69033745T2 (de) * 1989-07-11 2002-02-28 Genentech Inc Oberflächenaktive zusammensetzungen und verfahren
US5238920A (en) * 1989-08-22 1993-08-24 Abbott Laboratories Pulmonary surfactant protein fragments

Also Published As

Publication number Publication date
EP0458167A1 (de) 1991-11-27
CA2042635A1 (en) 1991-11-22
US5700777A (en) 1997-12-23
EP0458167B1 (de) 1997-04-23
US6022955A (en) 2000-02-08

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Legal Events

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