DE69125750D1 - Fettsäure-Oberflächenaktives-Lungenprotein Konjate - Google Patents

Fettsäure-Oberflächenaktives-Lungenprotein Konjate

Info

Publication number
DE69125750D1
DE69125750D1 DE69125750T DE69125750T DE69125750D1 DE 69125750 D1 DE69125750 D1 DE 69125750D1 DE 69125750 T DE69125750 T DE 69125750T DE 69125750 T DE69125750 T DE 69125750T DE 69125750 D1 DE69125750 D1 DE 69125750D1
Authority
DE
Germany
Prior art keywords
conjate
fatty acid
acid surfactant
lung protein
surfactant lung
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69125750T
Other languages
English (en)
Inventor
Virender Kumar Sarin
Shanker Lal Gupta
Darryl Robin Absolom
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Application granted granted Critical
Publication of DE69125750D1 publication Critical patent/DE69125750D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
DE69125750T 1990-05-21 1991-05-14 Fettsäure-Oberflächenaktives-Lungenprotein Konjate Expired - Lifetime DE69125750D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52558190A 1990-05-21 1990-05-21

Publications (1)

Publication Number Publication Date
DE69125750D1 true DE69125750D1 (de) 1997-05-28

Family

ID=24093832

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69125750T Expired - Lifetime DE69125750D1 (de) 1990-05-21 1991-05-14 Fettsäure-Oberflächenaktives-Lungenprotein Konjate

Country Status (4)

Country Link
US (2) US6022955A (de)
EP (1) EP0458167B1 (de)
CA (1) CA2042635A1 (de)
DE (1) DE69125750D1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
DE69332654T2 (de) * 1992-04-10 2003-09-25 Abbott Lab Fragmente eines oberflächenaktiven lungenproteins
FR2739860B1 (fr) * 1995-10-17 1998-01-02 Coletica Complexes amphiphiles, procede pour leur preparation et compositions en renfermant
US5958902A (en) * 1997-04-16 1999-09-28 Wisconsin Alumni Research Foundation Method and composition for treating sleep apnea
WO2000078810A1 (en) 1999-06-17 2000-12-28 Byk Gulden Lomberg Chemische Fabrik Gmbh Surfactant protein c esters
AU3844201A (en) 2000-02-16 2001-08-27 Univ Northwestern Polypeptoid pulmonary surfactants
JP2005511111A (ja) * 2001-06-29 2005-04-28 エシコン・インコーポレイテッド 排尿機能を評価するためのシステム及び方法
US7004899B2 (en) * 2001-06-29 2006-02-28 Ethicon, Inc. System and method for assessing urinary function
US7125568B2 (en) * 2001-08-23 2006-10-24 Sung Michael T Lipophilic drug compositions
WO2005063792A2 (en) * 2003-12-31 2005-07-14 F. Hoffmann-La Roche Ag Methods for recovering cleaved peptide from a support
US7464012B2 (en) * 2004-12-10 2008-12-09 L'air Liquide, Societe Anonyme A Directoire Et Conseil De Surveillance Pour L'etude Et L'exploitation Des Procedes Georges Claude Simplified process simulator
US7582312B2 (en) * 2004-11-15 2009-09-01 Discovery Laboratories, Inc. Methods to produce lung surfactant formulations via lyophilization and formulations and uses thereof
US7541331B2 (en) 2005-01-06 2009-06-02 Discovery Laboratories, Inc. Surfactant treatment regimen
US8221772B2 (en) * 2006-09-19 2012-07-17 Discovery Laboratories Inc. Pulmonary surfactant formulations and methods for promoting mucus clearance
CN101754747A (zh) * 2007-06-05 2010-06-23 Paka肺部医药公司 用于向肺脏递送药物的方法以及组合物
AU2009324637B2 (en) 2008-12-10 2016-09-08 Paka Pulmonary Pharmaceuticals, Inc. Methods and compositions for delivery of medicaments to the lungs
AU2010336981B2 (en) 2009-12-31 2014-04-10 Kempharm, Inc. Amino acid conjugates of quetiapine, process for making and using the same
US20110223207A1 (en) 2010-03-11 2011-09-15 Travis Mickle Fatty Acid Conjugates of Quetiapine, Process for Making and Using the Same
WO2013188016A2 (en) 2012-05-04 2013-12-19 Discovery Laboratories, Inc. Surfactant therapy for exposure to ionizing radiation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4234475A (en) * 1975-08-15 1980-11-18 The Gillette Company Reacting protein with organic acid
US4406833A (en) * 1982-06-04 1983-09-27 Fats And Proteins Research Foundation, Inc. Surfactants derived from fatty acid esters and proteinaceous material
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
US4933280A (en) * 1984-12-11 1990-06-12 California Biotechnology Inc. Recombinant DNA sequence encoding Alveolar Surfactant Protein
US4882422A (en) * 1985-10-24 1989-11-21 Genetics Institute, Inc. Pulmonary surfactant proteins
US4918161A (en) * 1985-09-26 1990-04-17 Genetics Institute, Inc. Low molecular weight pulmonary surfactant proteins
WO1987002037A1 (en) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Pulmonary surfactant proteins
JPS63503222A (ja) * 1986-05-06 1988-11-24 サイオス　ノバ　インコーポレイテッド 肺の疎水性界面活性物質に結合した分子量６，０００ダルトンのタンパク質及びその多量体
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
WO1988003170A1 (en) * 1986-10-24 1988-05-05 Whitsett Jeffrey A Pulmonary hydrophobic surfactant-associated proteins
US4861756A (en) * 1988-03-08 1989-08-29 Merrell Dow Pharmaceuticals Inc. Synthetic pulmonary surfactant
AU3073789A (en) * 1988-03-31 1989-10-05 Abbott Laboratories Drug delivery using pulmonary surfactant to facilitate absorption
NZ229737A (en) * 1988-07-01 1991-05-28 Merrell Dow Pharma Polypeptides and derivatives of them with lung surfactant properties and their preparation
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
ATE201880T1 (de) * 1989-07-11 2001-06-15 Genentech Inc Oberflächenaktive zusammensetzungen und verfahren
US5238920A (en) * 1989-08-22 1993-08-24 Abbott Laboratories Pulmonary surfactant protein fragments

Also Published As

Publication number Publication date
EP0458167B1 (de) 1997-04-23
US6022955A (en) 2000-02-08
EP0458167A1 (de) 1991-11-27
CA2042635A1 (en) 1991-11-22
US5700777A (en) 1997-12-23

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Legal Events

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8332 No legal effect for de