IL90220A0 - Anticoagulant peptide alcohols - Google Patents

Anticoagulant peptide alcohols

Info

Publication number
IL90220A0
IL90220A0 IL90220A IL9022089A IL90220A0 IL 90220 A0 IL90220 A0 IL 90220A0 IL 90220 A IL90220 A IL 90220A IL 9022089 A IL9022089 A IL 9022089A IL 90220 A0 IL90220 A0 IL 90220A0
Authority
IL
Israel
Prior art keywords
anticoagulant peptide
peptide alcohols
alcohols
anticoagulant
formula
Prior art date
Application number
IL90220A
Other languages
English (en)
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL90220A0 publication Critical patent/IL90220A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/02—Peptides of undefined number of amino acids; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IL90220A 1988-05-10 1989-05-08 Anticoagulant peptide alcohols IL90220A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19240988A 1988-05-10 1988-05-10

Publications (1)

Publication Number Publication Date
IL90220A0 true IL90220A0 (en) 1989-12-15

Family

ID=22709524

Family Applications (1)

Application Number Title Priority Date Filing Date
IL90220A IL90220A0 (en) 1988-05-10 1989-05-08 Anticoagulant peptide alcohols

Country Status (18)

Country Link
EP (1) EP0341607B1 (xx)
JP (1) JP2916164B2 (xx)
KR (1) KR0131378B1 (xx)
CN (1) CN1041157A (xx)
AT (1) ATE108801T1 (xx)
AU (1) AU626070B2 (xx)
CA (1) CA1341354C (xx)
DE (1) DE68916850T2 (xx)
DK (1) DK226889A (xx)
ES (1) ES2060689T3 (xx)
FI (1) FI892222A (xx)
HU (1) HU202556B (xx)
IL (1) IL90220A0 (xx)
NO (1) NO891894L (xx)
NZ (1) NZ228995A (xx)
PH (1) PH26973A (xx)
PT (1) PT90504B (xx)
ZA (1) ZA893346B (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU633128B2 (en) * 1987-01-23 1993-01-21 Merrell Dow Pharmaceuticals Inc. Anticoagulant peptides
US5240913A (en) * 1989-08-18 1993-08-31 Biogen, Inc. Inhibitors of thrombin
US5196404B1 (en) * 1989-08-18 1996-09-10 Biogen Inc Inhibitors of thrombin
US6060451A (en) * 1990-06-15 2000-05-09 The National Research Council Of Canada Thrombin inhibitors based on the amino acid sequence of hirudin
US5574012A (en) * 1990-07-24 1996-11-12 Merrell Pharmaceuticals Inc. Analogs of hirudin having anti-platelet activity
HUT63180A (en) * 1990-07-24 1993-07-28 Merrell Dow Pharma Process for producing anticoagulant peptides
ZA915658B (en) * 1990-07-24 1992-05-27 Merrell Dow Pharma Analogs of hirudin having antiplatelet activity
US5242810A (en) * 1990-12-07 1993-09-07 Biogen, Inc. Bifunctional inhibitors of thrombin and platelet activation
DE69432983T2 (de) * 1993-06-11 2004-04-29 Merrell Pharmaceuticals Inc., Cincinnati Trifunktionelle antithrombin-und antiplättchenpeptide
GB9426038D0 (en) 1994-12-22 1995-02-22 Iaf Biochem Int Low molecular weight bicyclic thrombin inhibitors
US6057314A (en) * 1995-12-21 2000-05-02 Biochem Pharma Inc. Low molecular weight bicyclic thrombin inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3438296A1 (de) * 1984-04-18 1985-11-07 Hoechst Ag, 6230 Frankfurt Neue polypeptide mit blutgerinnungshemmender wirkung, verfahren zu deren herstellung bzw. gewinnung, deren verwendung und diese enthaltende mittel
CA1341032C (en) * 1987-01-23 2000-06-20 John L. Krstenansky Anticoagulant peptides
ZA883443B (en) * 1987-05-21 1988-11-16 Merrell Dow Pharmaceuticals Inc. Cyclic anticoagulant peptides
CA1328540C (en) * 1987-05-21 1994-04-12 John L. Krstenansky Cyclic anticoagulant peptides

Also Published As

Publication number Publication date
ES2060689T3 (es) 1994-12-01
HUT51295A (en) 1990-04-28
KR900018138A (ko) 1990-12-20
ATE108801T1 (de) 1994-08-15
ZA893346B (en) 1990-01-31
JPH01313500A (ja) 1989-12-18
NO891894L (no) 1989-11-13
DE68916850D1 (de) 1994-08-25
FI892222A0 (fi) 1989-05-09
FI892222A (fi) 1989-11-11
EP0341607A2 (en) 1989-11-15
PT90504A (pt) 1989-11-30
EP0341607B1 (en) 1994-07-20
PT90504B (pt) 1994-08-31
JP2916164B2 (ja) 1999-07-05
AU626070B2 (en) 1992-07-23
HU202556B (en) 1991-03-28
DK226889D0 (da) 1989-05-09
NZ228995A (en) 1992-03-26
EP0341607A3 (en) 1991-03-27
AU3451789A (en) 1989-11-16
DK226889A (da) 1989-11-11
CN1041157A (zh) 1990-04-11
DE68916850T2 (de) 1994-10-27
CA1341354C (en) 2002-04-02
KR0131378B1 (ko) 1998-04-11
NO891894D0 (no) 1989-05-09
PH26973A (en) 1992-12-28

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.