IL89459A - 4-substituted pyrazolo (4,3-d) pyrimidine derivatives, their preparation and pharmaceutical compositions containing them - Google Patents

4-substituted pyrazolo (4,3-d) pyrimidine derivatives, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL89459A
IL89459A IL89459A IL8945989A IL89459A IL 89459 A IL89459 A IL 89459A IL 89459 A IL89459 A IL 89459A IL 8945989 A IL8945989 A IL 8945989A IL 89459 A IL89459 A IL 89459A
Authority
IL
Israel
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
pyrimidine derivatives
substituted pyrazolo
Prior art date
Application number
IL89459A
Other languages
English (en)
Other versions
IL89459A0 (en
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of IL89459A0 publication Critical patent/IL89459A0/xx
Publication of IL89459A publication Critical patent/IL89459A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL89459A 1988-03-03 1989-03-02 4-substituted pyrazolo (4,3-d) pyrimidine derivatives, their preparation and pharmaceutical compositions containing them IL89459A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/163,488 US4885300A (en) 1988-03-03 1988-03-03 4-Substituted pyrazolo[3,4-D]pyrimidine derivatives

Publications (2)

Publication Number Publication Date
IL89459A0 IL89459A0 (en) 1989-09-10
IL89459A true IL89459A (en) 1993-04-04

Family

ID=22590219

Family Applications (1)

Application Number Title Priority Date Filing Date
IL89459A IL89459A (en) 1988-03-03 1989-03-02 4-substituted pyrazolo (4,3-d) pyrimidine derivatives, their preparation and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (3) US4885300A (fi)
EP (1) EP0331510A3 (fi)
JP (1) JP2567936B2 (fi)
KR (1) KR940002827B1 (fi)
CN (1) CN1030605C (fi)
AU (1) AU612797B2 (fi)
DK (1) DK101689A (fi)
FI (1) FI92202C (fi)
HU (1) HU204274B (fi)
IL (1) IL89459A (fi)
NO (1) NO169966C (fi)
NZ (1) NZ228168A (fi)
PH (1) PH25999A (fi)
PT (1) PT89904B (fi)
ZA (1) ZA891620B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3712735A1 (de) * 1987-04-15 1988-11-10 Boehringer Mannheim Gmbh Neue pyrazolo(3,4-d)pyrimidine, verfahren zu ihrer herstellung und verwendung als arzneimittel
DE69112234T2 (de) * 1990-01-30 1996-04-04 Visa Int Service Ass Internationales Autorisierungssystem.
JP2651043B2 (ja) * 1990-07-10 1997-09-10 麒麟麦酒株式会社 ジフェニルメチルピペラジン誘導体
US5646152A (en) * 1994-06-15 1997-07-08 Pfizer Inc. Methods of administering CRF antagonists
DE69717653T2 (de) * 1996-09-18 2003-09-25 Daiso Co Ltd Verfahren zur herstellung von glycidylethern
EP0930291B1 (en) * 1996-09-18 2002-08-14 Daiso Co., Ltd. Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers
CN106070266B (zh) * 2016-06-29 2018-11-30 贵州大学 吡唑[3,4-d]嘧啶酮席夫碱类化合物在制备抗植物病毒剂中的应用
EP3575289B1 (en) * 2017-01-26 2023-04-19 Tosoh Corporation Alkanolamine, friction-reducing agent, and lubricating oil composition
JP2020527133A (ja) 2017-06-20 2020-09-03 インブリア ファーマシューティカルズ， インコーポレイテッド 心臓代謝の効率を高めるための組成物および方法
US11530184B2 (en) 2020-06-30 2022-12-20 Imbria Pharmaceuticals, Inc. Crystal forms of 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11780811B2 (en) 2020-06-30 2023-10-10 Imbria Pharmaceuticals, Inc. Methods of synthesizing 2-[4-[(2,3,4-trimethoxyphenyl)methyl]piperazin-1-yl]ethyl pyridine-3-carboxylate
US11883396B2 (en) 2021-05-03 2024-01-30 Imbria Pharmaceuticals, Inc. Methods of treating kidney conditions using modified forms of trimetazidine

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139705A (en) * 1977-05-20 1979-02-13 The Dow Chemical Company Pyrazolopyrimidines
FR2431710A1 (fr) * 1978-07-18 1980-02-15 Elf Aquitaine Procede d'exploration sismique par diagraphie acoustique
DE3200304A1 (de) * 1981-01-16 1982-08-26 Sandoz-Patent-GmbH, 7850 Lörrach 3-aminopropoxyaryl-derivate, ihre herstellung und sie enthaltende arzneimittel
DE3131365A1 (de) * 1981-08-07 1983-02-24 Henkel KGaA, 4000 Düsseldorf Neue diglycidyl-substituierte heterocyclische verbindungen, verfahren zu ihrer herstellung und ihre verwendung in arzneimittelzubereitungen mit cytostatischer wirksamkeit
US4460303A (en) * 1982-07-29 1984-07-17 Ingersoll-Rand Company Drill pipe loader
US4603203A (en) * 1983-12-14 1986-07-29 Takeda Chemical Industries, Ltd. 3-aminopyrazolo[3,4-d]pyrimidine derivatives and production thereof
DE3423092A1 (de) * 1984-06-22 1986-01-02 Dr. Karl Thomae Gmbh, 7950 Biberach Neue 8-alkylthio-2-piperazino-pyrimido(5,4-d) pyrimidine, ihre herstellung und diese verbindungen enthaltende arzneimittel
HU198052B (en) * 1986-02-14 1989-07-28 Sandoz Ag Process for producing purine derivatives substituted by side chain containing piperazinyl ring and pharmaceutical compositions comprising such compounds
US4876257A (en) * 1988-03-03 1989-10-24 Ortho Pharmaceutical Corporation 6-Substituted purinyl piperazine derivatives useful as cardiotonic and antiarrhythmic agents

Also Published As

Publication number Publication date
JP2567936B2 (ja) 1996-12-25
PH25999A (en) 1992-01-13
NO169966B (no) 1992-05-18
NO890894D0 (no) 1989-03-02
FI891004A0 (fi) 1989-03-02
FI92202C (fi) 1994-10-10
IL89459A0 (en) 1989-09-10
ZA891620B (en) 1990-11-28
JPH01279890A (ja) 1989-11-10
HU204274B (en) 1991-12-30
FI891004A (fi) 1989-09-04
AU612797B2 (en) 1991-07-18
US5001127A (en) 1991-03-19
KR940002827B1 (ko) 1994-04-04
HUT49353A (en) 1989-09-28
AU3088389A (en) 1989-09-07
FI92202B (fi) 1994-06-30
US4885300A (en) 1989-12-05
KR890014542A (ko) 1989-10-24
EP0331510A2 (en) 1989-09-06
PT89904B (pt) 1994-11-30
NO169966C (no) 1992-08-26
CN1030605C (zh) 1996-01-03
DK101689D0 (da) 1989-03-02
USRE35072E (en) 1995-10-24
DK101689A (da) 1989-09-04
EP0331510A3 (en) 1991-03-13
NO890894L (no) 1989-09-04
NZ228168A (en) 1991-07-26
PT89904A (pt) 1989-11-10
CN1036766A (zh) 1989-11-01

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Legal Events

Date Code Title Description
RH Patent void