IL86090A - Production of purified, biologically active, bacterially produced recombinant human csf-1 - Google Patents

Production of purified, biologically active, bacterially produced recombinant human csf-1

Info

Publication number
IL86090A
IL86090A IL86090A IL8609088A IL86090A IL 86090 A IL86090 A IL 86090A IL 86090 A IL86090 A IL 86090A IL 8609088 A IL8609088 A IL 8609088A IL 86090 A IL86090 A IL 86090A
Authority
IL
Israel
Prior art keywords
biologically active
human csf
purified
production
recombinant human
Prior art date
Application number
IL86090A
Other languages
English (en)
Other versions
IL86090A0 (en
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Publication of IL86090A0 publication Critical patent/IL86090A0/xx
Publication of IL86090A publication Critical patent/IL86090A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL86090A 1987-04-16 1988-04-15 Production of purified, biologically active, bacterially produced recombinant human csf-1 IL86090A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4017487A 1987-04-16 1987-04-16
US11400187A 1987-10-27 1987-10-27

Publications (2)

Publication Number Publication Date
IL86090A0 IL86090A0 (en) 1988-09-30
IL86090A true IL86090A (en) 1993-03-15

Family

ID=26716797

Family Applications (1)

Application Number Title Priority Date Filing Date
IL86090A IL86090A (en) 1987-04-16 1988-04-15 Production of purified, biologically active, bacterially produced recombinant human csf-1

Country Status (10)

Country Link
EP (2) EP0309569B1 (fr)
JP (1) JP2656964B2 (fr)
AT (2) ATE301133T1 (fr)
AU (1) AU610182B2 (fr)
BG (1) BG49827A3 (fr)
DE (2) DE3856581T2 (fr)
FI (1) FI96872C (fr)
IL (1) IL86090A (fr)
NO (1) NO300067B1 (fr)
WO (1) WO1988008003A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
WO1989010407A1 (fr) * 1988-04-29 1989-11-02 Genetics Institute, Inc. M-csf dimerique homogene et formulations stables pendant le stockage
EP0410751B1 (fr) * 1989-07-27 1996-04-10 Denki Kagaku Kogyo Kabushiki Kaisha Gène codant pour M-CSF et systèmes recombinants pour cela
GB8927546D0 (en) * 1989-12-06 1990-02-07 Ciba Geigy Process for the production of biologically active tgf-beta
AU8417091A (en) * 1990-08-20 1992-03-17 Novo Nordisk A/S Biologically active compound, a process for the preparation thereof and use of the same
DE69129747T2 (de) * 1990-09-05 1998-11-12 Southern Cross Biotech Pty. Ltd., Toorak, Victoria In lösung bringen von proteinen in aktiver form
US5288931A (en) * 1991-12-06 1994-02-22 Genentech, Inc. Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation
EP0668914B1 (fr) * 1992-06-09 2000-08-16 Chiron Corporation Cristallisation du m-csf
AU661914B2 (en) * 1992-08-18 1995-08-10 Jean-Louis Odore Support structure for a shelter cover
HUT72926A (en) * 1993-08-04 1996-06-28 Ciba Geigy Ag High molecular weight desulphatohirudin
US5663304A (en) * 1993-08-20 1997-09-02 Genentech, Inc. Refolding of misfolded insulin-like growth factor-I
US5407810A (en) * 1993-08-20 1995-04-18 Genentech, Inc. Aqueous multiple-phase isolation of polypeptide
TW517059B (en) 1994-07-25 2003-01-11 Ciba Geigy Ag New process for the production of biologically active protein
FR2796071B1 (fr) * 1999-07-08 2001-09-07 Hoechst Marion Roussel Inc Procede de purification de facteur de stimulation de colonies de granulocytes
US6808902B1 (en) * 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
DE102004041639A1 (de) * 2004-08-27 2006-03-02 Bioceuticals Arzneimittel Ag Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies
EA020621B1 (ru) 2009-06-22 2014-12-30 Амген Инк. Рефолдинг белков с использованием химически контролируемого окислительно-восстановительного состояния
EP3660032A1 (fr) 2009-06-25 2020-06-03 Amgen, Inc Processus de purification de capture pour protéines exprimées dans un système non mammifère
DE202009019091U1 (de) 2009-12-21 2016-05-23 Agilent Technologies, Inc. - A Delaware Corporation - Fittingelement mit frontseitiger Einlage

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR79124B (fr) * 1982-12-22 1984-10-02 Genentech Inc
WO1986004607A1 (fr) * 1985-02-05 1986-08-14 Cetus Corporation Facteur-1 recombinant stimulant la formation de colonies
ATE92966T1 (de) * 1986-05-06 1993-08-15 Genetics Inst Herstellung von m-csf.
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer

Also Published As

Publication number Publication date
EP0818466B1 (fr) 2005-08-03
AU1712488A (en) 1988-11-04
NO300067B1 (no) 1997-04-01
IL86090A0 (en) 1988-09-30
EP0309569B1 (fr) 1998-06-10
ATE301133T1 (de) 2005-08-15
FI885807A0 (fi) 1988-12-15
NO885555L (no) 1989-01-11
DE3856203D1 (de) 1998-07-16
AU610182B2 (en) 1991-05-16
NO885555D0 (no) 1988-12-14
DE3856203T2 (de) 1998-10-08
DE3856581T2 (de) 2006-05-24
EP0818466A3 (fr) 1998-03-25
FI96872B (fi) 1996-05-31
WO1988008003A1 (fr) 1988-10-20
EP0818466A2 (fr) 1998-01-14
BG49827A3 (en) 1992-02-14
FI885807A (fi) 1988-12-15
EP0309569A1 (fr) 1989-04-05
JPH01503440A (ja) 1989-11-22
ATE167192T1 (de) 1998-06-15
JP2656964B2 (ja) 1997-09-24
FI96872C (fi) 1996-09-10
DE3856581D1 (de) 2005-09-29

Similar Documents

Publication Publication Date Title
IL86090A (en) Production of purified, biologically active, bacterially produced recombinant human csf-1
MY103892A (en) Interleukin-2 of high purity production and use
AU595290B2 (en) Process for producing human epidermal growth factor and analogs thereof
AU704515C (en) Novel protein and process for producing the same
ES525948A0 (es) Un metodo de producir polipeptidos similares a la hormona del crecimiento porcina.
DE122004000009I2 (de) Methode zur Herstellung von menschlichen Wachstumshormonen
KR920004570A (ko) 사람 mk 단백질을 암호하는 유전자, 이를 포함하는 발현 벡터 및 숙주 세포, mk단백질의 생산 방법 및 사용방법
DE3175357D1 (en) Dna sequences encoding various allelic forms of mature thaumatin, recombinant plasmids comprising said dna's and a process for their preparation, bacterial cultures comprising said recombinant plasmids, and method for producing mature thaumatin
ATE283864T1 (de) Ein verfahren zur herstellung therapeutisch wirksamer bruchstücke von von willebrand-faktor
DE3855986D1 (de) Prozess zur gewinnung von gereinigtem, oxidiertem, renaturiertem, rekombinantem interleukin-2 aus mikroorganismen
NZ239249A (en) Pure gelonin toxin and its corresponding dna sequence
EP0317627A4 (en) Oncogene-encoded polypeptide having growth factor activity and methods of production and use thereof
DE69027466D1 (de) Achromobacter-Protease-I-Gen sowie Genprodukt
DE3886118D1 (de) Methode zur Reinigung von Interferon.
EP0280407A3 (fr) Procédé de production de polypeptides recombinants ayant l'activité de l'hormone de croissance porcine
BG96578A (bg) Метод за получаване на пречистени лизозимни димери
DE68928634D1 (de) Verfahren zur Herstellung von aktivierten Killer-Monozyten und Verfahren zur Überprüfung ihrer tumoriziden Aktivität
ATE107959T1 (de) Klonierung des isoamylaseenzym kodierenden gens und seine verwendung zur herstellung dieses enzyms.
ATE88188T1 (de) Verfahren zur herstellung von antihaemophilem faktor (faktor viii), der eine hohe reinheit aufweist.
ATE110112T1 (de) Verfahren und systeme zur herstellung von hiv- antigenen.
EP0603393A4 (fr) Interleukine 6 humaine de recombinaison avec terminaison n homogene et production de cette interleukine.
DE68913802D1 (de) Thymosin und TNF-kodierende DNA.
DE69126379D1 (de) Verfahren zur herstellung und reinigung des carboxyterminalen fragments der dna-polymerase i von streptococcus pneumoniae
ATE77240T1 (de) Fraktion von listeria monocytogenes mit therapeutischer wirkung, verfahren fuer ihre herstellung und diese enthaltende pharmazeutische zusammensetzung.

Legal Events

Date Code Title Description
HC Change of name of proprietor(s)
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired