IL86090A - Production of purified, biologically active, bacterially produced recombinant human csf-1 - Google Patents
Production of purified, biologically active, bacterially produced recombinant human csf-1Info
- Publication number
- IL86090A IL86090A IL86090A IL8609088A IL86090A IL 86090 A IL86090 A IL 86090A IL 86090 A IL86090 A IL 86090A IL 8609088 A IL8609088 A IL 8609088A IL 86090 A IL86090 A IL 86090A
- Authority
- IL
- Israel
- Prior art keywords
- biologically active
- human csf
- purified
- production
- recombinant human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
- C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4017487A | 1987-04-16 | 1987-04-16 | |
US11400187A | 1987-10-27 | 1987-10-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL86090A0 IL86090A0 (en) | 1988-09-30 |
IL86090A true IL86090A (en) | 1993-03-15 |
Family
ID=26716797
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL86090A IL86090A (en) | 1987-04-16 | 1988-04-15 | Production of purified, biologically active, bacterially produced recombinant human csf-1 |
Country Status (10)
Country | Link |
---|---|
EP (2) | EP0309569B1 (fr) |
JP (1) | JP2656964B2 (fr) |
AT (2) | ATE301133T1 (fr) |
AU (1) | AU610182B2 (fr) |
BG (1) | BG49827A3 (fr) |
DE (2) | DE3856581T2 (fr) |
FI (1) | FI96872C (fr) |
IL (1) | IL86090A (fr) |
NO (1) | NO300067B1 (fr) |
WO (1) | WO1988008003A1 (fr) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5650297A (en) * | 1986-09-17 | 1997-07-22 | Otsuka Pharmaceutical Co., Ltd. | DNA encoding human colony-stimulating factors |
US4931543A (en) * | 1987-05-11 | 1990-06-05 | Cetus Corporation | Process for recovering microbially produced interleukin-2 |
WO1989010407A1 (fr) * | 1988-04-29 | 1989-11-02 | Genetics Institute, Inc. | M-csf dimerique homogene et formulations stables pendant le stockage |
EP0410751B1 (fr) * | 1989-07-27 | 1996-04-10 | Denki Kagaku Kogyo Kabushiki Kaisha | Gène codant pour M-CSF et systèmes recombinants pour cela |
GB8927546D0 (en) * | 1989-12-06 | 1990-02-07 | Ciba Geigy | Process for the production of biologically active tgf-beta |
AU8417091A (en) * | 1990-08-20 | 1992-03-17 | Novo Nordisk A/S | Biologically active compound, a process for the preparation thereof and use of the same |
DE69129747T2 (de) * | 1990-09-05 | 1998-11-12 | Southern Cross Biotech Pty. Ltd., Toorak, Victoria | In lösung bringen von proteinen in aktiver form |
US5288931A (en) * | 1991-12-06 | 1994-02-22 | Genentech, Inc. | Method for refolding insoluble, misfolded insulin-like growth factor-I into an active conformation |
EP0668914B1 (fr) * | 1992-06-09 | 2000-08-16 | Chiron Corporation | Cristallisation du m-csf |
AU661914B2 (en) * | 1992-08-18 | 1995-08-10 | Jean-Louis Odore | Support structure for a shelter cover |
HUT72926A (en) * | 1993-08-04 | 1996-06-28 | Ciba Geigy Ag | High molecular weight desulphatohirudin |
US5663304A (en) * | 1993-08-20 | 1997-09-02 | Genentech, Inc. | Refolding of misfolded insulin-like growth factor-I |
US5407810A (en) * | 1993-08-20 | 1995-04-18 | Genentech, Inc. | Aqueous multiple-phase isolation of polypeptide |
TW517059B (en) | 1994-07-25 | 2003-01-11 | Ciba Geigy Ag | New process for the production of biologically active protein |
FR2796071B1 (fr) * | 1999-07-08 | 2001-09-07 | Hoechst Marion Roussel Inc | Procede de purification de facteur de stimulation de colonies de granulocytes |
US6808902B1 (en) * | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
DE102004041639A1 (de) * | 2004-08-27 | 2006-03-02 | Bioceuticals Arzneimittel Ag | Verfahren zur Gewinnung von biologisch aktivem humanen G-CSF aus Inclusion Bodies |
EA020621B1 (ru) | 2009-06-22 | 2014-12-30 | Амген Инк. | Рефолдинг белков с использованием химически контролируемого окислительно-восстановительного состояния |
EP3660032A1 (fr) | 2009-06-25 | 2020-06-03 | Amgen, Inc | Processus de purification de capture pour protéines exprimées dans un système non mammifère |
DE202009019091U1 (de) | 2009-12-21 | 2016-05-23 | Agilent Technologies, Inc. - A Delaware Corporation - | Fittingelement mit frontseitiger Einlage |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GR79124B (fr) * | 1982-12-22 | 1984-10-02 | Genentech Inc | |
WO1986004607A1 (fr) * | 1985-02-05 | 1986-08-14 | Cetus Corporation | Facteur-1 recombinant stimulant la formation de colonies |
ATE92966T1 (de) * | 1986-05-06 | 1993-08-15 | Genetics Inst | Herstellung von m-csf. |
DK54589A (da) * | 1988-02-08 | 1989-08-09 | Otsuka Pharma Co Ltd | Humane kolonistmulerende faktorer |
-
1988
- 1988-04-15 IL IL86090A patent/IL86090A/xx not_active IP Right Cessation
- 1988-04-18 DE DE3856581T patent/DE3856581T2/de not_active Expired - Lifetime
- 1988-04-18 AU AU17124/88A patent/AU610182B2/en not_active Expired
- 1988-04-18 JP JP63503965A patent/JP2656964B2/ja not_active Expired - Lifetime
- 1988-04-18 EP EP88904086A patent/EP0309569B1/fr not_active Expired - Lifetime
- 1988-04-18 WO PCT/US1988/001189 patent/WO1988008003A1/fr active IP Right Grant
- 1988-04-18 DE DE3856203T patent/DE3856203T2/de not_active Expired - Lifetime
- 1988-04-18 AT AT97202737T patent/ATE301133T1/de not_active IP Right Cessation
- 1988-04-18 EP EP97202737A patent/EP0818466B1/fr not_active Expired - Lifetime
- 1988-04-18 AT AT88904086T patent/ATE167192T1/de not_active IP Right Cessation
- 1988-12-14 NO NO885555A patent/NO300067B1/no not_active IP Right Cessation
- 1988-12-15 FI FI885807A patent/FI96872C/fi not_active IP Right Cessation
- 1988-12-16 BG BG86469A patent/BG49827A3/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0818466B1 (fr) | 2005-08-03 |
AU1712488A (en) | 1988-11-04 |
NO300067B1 (no) | 1997-04-01 |
IL86090A0 (en) | 1988-09-30 |
EP0309569B1 (fr) | 1998-06-10 |
ATE301133T1 (de) | 2005-08-15 |
FI885807A0 (fi) | 1988-12-15 |
NO885555L (no) | 1989-01-11 |
DE3856203D1 (de) | 1998-07-16 |
AU610182B2 (en) | 1991-05-16 |
NO885555D0 (no) | 1988-12-14 |
DE3856203T2 (de) | 1998-10-08 |
DE3856581T2 (de) | 2006-05-24 |
EP0818466A3 (fr) | 1998-03-25 |
FI96872B (fi) | 1996-05-31 |
WO1988008003A1 (fr) | 1988-10-20 |
EP0818466A2 (fr) | 1998-01-14 |
BG49827A3 (en) | 1992-02-14 |
FI885807A (fi) | 1988-12-15 |
EP0309569A1 (fr) | 1989-04-05 |
JPH01503440A (ja) | 1989-11-22 |
ATE167192T1 (de) | 1998-06-15 |
JP2656964B2 (ja) | 1997-09-24 |
FI96872C (fi) | 1996-09-10 |
DE3856581D1 (de) | 2005-09-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HC | Change of name of proprietor(s) | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |