IL84295A - Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes - Google Patents

Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes

Info

Publication number
IL84295A
IL84295A IL84295A IL8429587A IL84295A IL 84295 A IL84295 A IL 84295A IL 84295 A IL84295 A IL 84295A IL 8429587 A IL8429587 A IL 8429587A IL 84295 A IL84295 A IL 84295A
Authority
IL
Israel
Prior art keywords
measurement
changes
cell growth
growth rate
cyanine dye
Prior art date
Application number
IL84295A
Other languages
English (en)
Other versions
IL84295A0 (en
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of IL84295A0 publication Critical patent/IL84295A0/xx
Publication of IL84295A publication Critical patent/IL84295A/xx

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
    • A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
    • A61K49/0032—Methine dyes, e.g. cyanine dyes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
IL84295A 1986-10-31 1987-10-27 Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes IL84295A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/925,429 US4859584A (en) 1986-10-31 1986-10-31 Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes

Publications (2)

Publication Number Publication Date
IL84295A0 IL84295A0 (en) 1988-03-31
IL84295A true IL84295A (en) 1991-12-15

Family

ID=25451718

Family Applications (1)

Application Number Title Priority Date Filing Date
IL84295A IL84295A (en) 1986-10-31 1987-10-27 Cell growth rate determination by measurement of changes in cyanine dye levels in plasma membranes

Country Status (13)

Country Link
US (1) US4859584A (ko)
EP (1) EP0266196A3 (ko)
JP (1) JPS63122955A (ko)
KR (1) KR880005457A (ko)
CN (1) CN1014276B (ko)
AU (1) AU607944B2 (ko)
CA (1) CA1294544C (ko)
DK (1) DK560587A (ko)
IE (1) IE872873L (ko)
IL (1) IL84295A (ko)
PH (1) PH25250A (ko)
PT (1) PT86029B (ko)
ZA (1) ZA878115B (ko)

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DE68927479T2 (de) * 1988-05-02 1997-04-03 Phanos Tech Inc Verbindungen, zusammensetzungen und verfahren zum binden von bio-affektions-substanzen an oberflächenmembranen von bioteilchen
US5169788A (en) * 1989-06-09 1992-12-08 New England Deaconess Hospital Corporation Methods of measuring membrane potential using j-aggregate forming dyes
JP2824917B2 (ja) * 1989-08-30 1998-11-18 株式会社林原生物化学研究所 抗腫瘍剤
US5164301A (en) * 1990-06-22 1992-11-17 Difco Laboratories Process and kit for detecting microbial metabolism
JP3070968B2 (ja) * 1991-05-14 2000-07-31 シスメックス株式会社 尿中の細胞分析用試薬及び方法
DE69227112D1 (de) * 1991-07-16 1998-10-29 Transmed Biotech Inc Verfahren und zusammensetzungen für die gleichzeitige analyse einer vielzahl von analyten
US5306624A (en) * 1992-09-17 1994-04-26 Packard Instrument Co., Inc. Process of quantifying cell number
US5995645A (en) * 1993-08-18 1999-11-30 Applied Spectral Imaging Ltd. Method of cancer cell detection
DE19539409C2 (de) * 1995-10-11 1999-02-18 Diagnostikforschung Inst Kontrastmittel für die Nahinfrarot-Diagnostik
US6004536A (en) * 1995-11-14 1999-12-21 Molecular Probes, Inc. Lipophilic cyanine dyes with enchanced aqueous solubilty
US5804389A (en) * 1995-12-29 1998-09-08 Phanos Technologies, Inc. Method for detecting abnormal epithelial cell shedding
DE19603033A1 (de) 1996-01-19 1997-07-24 Schering Ag Perfluoralkylhaltige Metallkomplexe, Verfahren zu deren Herstellung und ihre Verwendung in der NMR-Diagnostik
US5989835A (en) * 1997-02-27 1999-11-23 Cellomics, Inc. System for cell-based screening
US6008010A (en) * 1996-11-01 1999-12-28 University Of Pittsburgh Method and apparatus for holding cells
EP0969878B1 (en) * 1997-02-04 2008-07-02 PHANOS TECHNOLOGIES, Inc. Method for detecting abnormal epithelial cell shedding
US6727071B1 (en) 1997-02-27 2004-04-27 Cellomics, Inc. System for cell-based screening
US7117098B1 (en) 1997-02-27 2006-10-03 Cellomics, Inc. Machine-readable storage medium for analyzing distribution of macromolecules between the cell membrane and the cell cytoplasm
ATE268008T1 (de) 1997-02-27 2004-06-15 Cellomics Inc Ein system zur zellbasierten reihenuntersuchung
JP2001518934A (ja) 1997-03-25 2001-10-16 ラスター，モーリス 移植部位としての骨髄
AU6164499A (en) 1998-09-25 2000-04-17 Xoma Technology Ltd. Identification of novel antimicrobial agents using membrane potential indicator dyes
US6986993B1 (en) 1999-08-05 2006-01-17 Cellomics, Inc. System for cell-based screening
US6944493B2 (en) * 1999-09-10 2005-09-13 Akora, Inc. Indocyanine green (ICG) compositions and related methods of use
US6351663B1 (en) 1999-09-10 2002-02-26 Akorn, Inc. Methods for diagnosing and treating conditions associated with abnormal vasculature using fluorescent dye angiography and dye-enhanced photocoagulation
US6673568B1 (en) * 1999-10-25 2004-01-06 Genprime, Inc. Method and apparatus for prokaryotic and eukaryotic cell quantitation
US6787302B2 (en) * 1999-10-25 2004-09-07 Genprime, Inc. Method and apparatus for prokaryotic and eukaryotic cell quantitation
US6443976B1 (en) 1999-11-30 2002-09-03 Akorn, Inc. Methods for treating conditions and illnesses associated with abnormal vasculature
US6716588B2 (en) 1999-12-09 2004-04-06 Cellomics, Inc. System for cell-based screening
JP2003519486A (ja) 2000-01-11 2003-06-24 グリーンビル ホスピタル システム 雑種細胞
US20090087450A1 (en) * 2000-01-11 2009-04-02 Greenville Hospital System Combination therapy of hybrid cells with BCG injection for treating Cancer Patients
US20070212338A1 (en) * 2000-01-11 2007-09-13 Greenville Hospital System Hybrid cells
DE60138531D1 (de) * 2000-03-03 2009-06-10 Phanos Tech Inc Fluoreszierende im membran interkalierende proben und verfahren zu deren verwendung
US6689391B2 (en) 2001-03-30 2004-02-10 Council Of Scientific & Industrial Research Natural non-polar fluorescent dye from a non-bioluminescent marine invertebrate, compositions containing the said dye and its uses
US20020159625A1 (en) * 2001-04-02 2002-10-31 Cytoprint, Inc. Method and apparatus for discovering, identifying and comparing biological activity mechanisms
US7776529B2 (en) 2003-12-05 2010-08-17 Life Technologies Corporation Methine-substituted cyanine dye compounds
US7282349B2 (en) * 2003-12-16 2007-10-16 Kimberly-Clark Worldwide, Inc. Solvatochromatic bacterial detection
CN101080497B (zh) * 2003-12-16 2010-12-29 金伯利-克拉克环球有限公司 微生物检测与定量
US7300770B2 (en) 2004-12-16 2007-11-27 Kimberly-Clark Worldwide, Inc. Detection of microbe contamination on elastomeric articles
US7399608B2 (en) 2003-12-16 2008-07-15 Kimberly-Clark Worldwide, Inc. Microbial detection and quantification
JP2008508888A (ja) * 2004-08-05 2008-03-27 ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ 細胞活性化のための方法および組成物
KR101219829B1 (ko) * 2004-12-16 2013-01-08 킴벌리-클라크 월드와이드, 인크. 탄성 용품 상의 미생물 오염 검출
KR101225911B1 (ko) * 2004-12-16 2013-01-24 킴벌리-클라크 월드와이드, 인크. 미생물의 검출 및 정량화
US7598390B2 (en) 2005-05-11 2009-10-06 Life Technologies Corporation Fluorescent chemical compounds having high selectivity for double stranded DNA, and methods for their use
AU2005234696B2 (en) 2005-11-18 2012-02-16 Phanos Technologies, Inc. Fluorescent membrane intercalating probes and methods for their use
US7727513B2 (en) 2005-12-15 2010-06-01 Kimberly-Clark Worldwide, Inc. Method for screening for bacterial conjunctivitis
CN101518528B (zh) * 2008-02-29 2014-02-26 史春梦 一组碳花青染料类的近红外荧光化合物的用途

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4168206A (en) * 1977-05-02 1979-09-18 Philadelphia College Of Osteopathic Medicine Impregnated disk method for testing antifungal susceptibility
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
US4225669A (en) * 1979-04-27 1980-09-30 Melnick Joseph L Staining and analysis of bacteria
US4232121A (en) * 1978-09-25 1980-11-04 Eastman Kodak Company Process for selecting methine dyes which inhibit cell growth
US4424201A (en) * 1978-11-28 1984-01-03 Rockefeller University Employment of a mereyanine dye for the detection of malignant leukocytic cells
EP0054001B1 (fr) * 1980-12-05 1985-04-03 Battelle Memorial Institute Méthode pour observer le développement de micro-organismes
US4423145A (en) * 1981-05-07 1983-12-27 Stampfer Martha R Enhanced growth medium and method for culturing human mammary epithelial cells
US4559299A (en) * 1983-02-04 1985-12-17 Brown University Research Foundation Inc. Cytotoxicity assays in cell culturing devices
US4783401A (en) * 1986-10-31 1988-11-08 Smithkline Beckman Corporation Viable cell labelling

Also Published As

Publication number Publication date
US4859584A (en) 1989-08-22
PT86029A (en) 1987-11-01
JPS63122955A (ja) 1988-05-26
CN87107220A (zh) 1988-05-11
PT86029B (pt) 1990-08-31
IL84295A0 (en) 1988-03-31
ZA878115B (en) 1988-09-28
DK560587A (da) 1988-05-01
KR880005457A (ko) 1988-06-29
EP0266196A3 (en) 1990-05-23
PH25250A (en) 1991-03-27
IE872873L (en) 1988-04-30
CN1014276B (zh) 1991-10-09
AU8040287A (en) 1988-05-05
EP0266196A2 (en) 1988-05-04
AU607944B2 (en) 1991-03-21
CA1294544C (en) 1992-01-21
DK560587D0 (da) 1987-10-26

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Legal Events

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MM9K Patent not in force due to non-payment of renewal fees