IL83775A - Amino acid esters and amides of fumaric acid and pharmaceutical compositions containing them for use in the treatment of psoriasis - Google Patents

Amino acid esters and amides of fumaric acid and pharmaceutical compositions containing them for use in the treatment of psoriasis

Info

Publication number
IL83775A
IL83775A IL83775A IL8377587A IL83775A IL 83775 A IL83775 A IL 83775A IL 83775 A IL83775 A IL 83775A IL 8377587 A IL8377587 A IL 8377587A IL 83775 A IL83775 A IL 83775A
Authority
IL
Israel
Prior art keywords
psoriasis
treatment
amides
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL83775A
Other languages
English (en)
Other versions
IL83775A0 (en
Original Assignee
Dexter Chemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dexter Chemical Corp filed Critical Dexter Chemical Corp
Priority to IL83775A priority Critical patent/IL83775A/xx
Publication of IL83775A0 publication Critical patent/IL83775A0/xx
Priority to ZA886097A priority patent/ZA886097B/xx
Priority to CA000575813A priority patent/CA1340005C/en
Priority to IN611/MAS/88A priority patent/IN167848B/en
Priority to EP88908544A priority patent/EP0328634B1/en
Priority to AT88908544T priority patent/ATE124681T1/de
Priority to DE3854121T priority patent/DE3854121T2/de
Priority to AU24237/88A priority patent/AU618759B2/en
Priority to KR1019890700794A priority patent/KR890701545A/ko
Priority to JP63507740A priority patent/JPH0745451B2/ja
Priority to PCT/US1988/002941 priority patent/WO1989001930A1/en
Priority to NO891703A priority patent/NO891703D0/no
Priority to FI891986A priority patent/FI891986A0/fi
Priority to DK218189A priority patent/DK218189A/da
Priority to US07/732,342 priority patent/US5242905A/en
Priority to US07/763,188 priority patent/US5214196A/en
Publication of IL83775A publication Critical patent/IL83775A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/09—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an acyclic unsaturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/49—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a carbon atom of an acyclic unsaturated carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/52—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the nitrogen atom of at least one of the carboxamide groups further acylated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
IL83775A 1987-04-09 1987-09-04 Amino acid esters and amides of fumaric acid and pharmaceutical compositions containing them for use in the treatment of psoriasis IL83775A (en)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IL83775A IL83775A (en) 1987-09-04 1987-09-04 Amino acid esters and amides of fumaric acid and pharmaceutical compositions containing them for use in the treatment of psoriasis
ZA886097A ZA886097B (en) 1987-09-04 1988-08-17 Pharmaceutical composition for the treatment of psoriasis
CA000575813A CA1340005C (en) 1987-04-09 1988-08-26 Pharmaceutical composition for the treatment of psoriasis
IN611/MAS/88A IN167848B (fi) 1987-09-04 1988-08-30
PCT/US1988/002941 WO1989001930A1 (en) 1987-09-04 1988-09-01 Pharmaceutical compositions for the treatment of psoriasis
DE3854121T DE3854121T2 (de) 1987-09-04 1988-09-01 Arzneimittelzusammensetzungen zur behandlung von psoriasis.
AT88908544T ATE124681T1 (de) 1987-09-04 1988-09-01 Arzneimittelzusammensetzungen zur behandlung von psoriasis.
EP88908544A EP0328634B1 (en) 1987-09-04 1988-09-01 Pharmaceutical compositions for the treatment of psoriasis
AU24237/88A AU618759B2 (en) 1987-09-04 1988-09-01 Pharmaceutical compositions for the treatment of psoriasis
KR1019890700794A KR890701545A (ko) 1987-09-04 1988-09-01 건선치료를 위한 제약학적 조성물
JP63507740A JPH0745451B2 (ja) 1987-09-04 1988-09-01 乾せん症処置用医薬組成物
NO891703A NO891703D0 (no) 1987-09-04 1989-04-25 Farmasoeytiske sammensetninger for behandling av psoriasis.
FI891986A FI891986A0 (fi) 1987-09-04 1989-04-26 Farmaceutiska sammansaettningar foer behandling av psoriasis.
DK218189A DK218189A (da) 1987-09-04 1989-05-03 Fumarsyrekonjugat og farmaceutisk praeparat indeholdende en saadan forbindelse
US07/732,342 US5242905A (en) 1987-09-04 1991-07-17 Pharmaceutical compositions for the treatment of psoriasis
US07/763,188 US5214196A (en) 1987-09-04 1991-09-20 Diethyl ester of di-glycyl fumaramide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL83775A IL83775A (en) 1987-09-04 1987-09-04 Amino acid esters and amides of fumaric acid and pharmaceutical compositions containing them for use in the treatment of psoriasis

Publications (2)

Publication Number Publication Date
IL83775A0 IL83775A0 (en) 1988-02-29
IL83775A true IL83775A (en) 1991-12-15

Family

ID=11058151

Family Applications (1)

Application Number Title Priority Date Filing Date
IL83775A IL83775A (en) 1987-04-09 1987-09-04 Amino acid esters and amides of fumaric acid and pharmaceutical compositions containing them for use in the treatment of psoriasis

Country Status (14)

Country Link
EP (1) EP0328634B1 (fi)
JP (1) JPH0745451B2 (fi)
KR (1) KR890701545A (fi)
AT (1) ATE124681T1 (fi)
AU (1) AU618759B2 (fi)
CA (1) CA1340005C (fi)
DE (1) DE3854121T2 (fi)
DK (1) DK218189A (fi)
FI (1) FI891986A0 (fi)
IL (1) IL83775A (fi)
IN (1) IN167848B (fi)
NO (1) NO891703D0 (fi)
WO (1) WO1989001930A1 (fi)
ZA (1) ZA886097B (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290769A (en) * 1989-09-27 1994-03-01 Asta Pharma Aktiengesellschaft Use of hexadecylphosphocholine for the treatment of psoriasis
AU1271592A (en) * 1991-01-18 1992-08-27 Dexter Chemical Corporation Malic acid derivatives and compositions for the treatment of psoriasis
US5856418A (en) * 1996-04-16 1999-01-05 Nippon Shokubai Co., Ltd. Water-soluble monomer, water-soluble polymer and their production process and use
DE19853487A1 (de) 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
RS52083B (sr) * 2001-01-12 2012-06-30 Fumapharm Ag Amidi fumarne kiseline
DE10217314A1 (de) * 2002-04-18 2003-11-13 Fumapharm Ag Muri Carbocyclische und Oxacarboncyclische Fumarsäure-Oligomere
EP1663197B1 (en) 2003-09-09 2007-12-05 Fumapharm AG The use of fumaric acid derivatives for treating cardiac insufficiency, and asthma
FI121915B (fi) * 2004-02-06 2011-06-15 Neurofood Ab Oy Koostumus psoriasiksen hoitoon
LT2801354T (lt) 2004-10-08 2017-06-26 Forward Pharma A/S Kontroliuojamo atpalaidavimo farmacinės kompozicijos, apimančios fumaro rūgšties esterį
HRP20220902T3 (hr) 2007-02-08 2022-10-14 Biogen Ma Inc. Pripravci i njihova upotreba u liječenju multiple skleroze
US20100158829A1 (en) * 2008-12-24 2010-06-24 Conopco, Inc., D/B/A Unilever Method and Composition for Color Modulation
US8906420B2 (en) 2009-01-09 2014-12-09 Forward Pharma A/S Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
NZ601698A (en) 2010-01-08 2015-04-24 Catabasis Pharmaceuticals Inc Fatty acid fumarate derivatives and their uses

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE790032A (fr) * 1971-10-27 1973-02-01 Elf Union Procede de fonctionnement de bruleurs a emulsion a deux allures
JPS4852741A (fi) * 1971-11-04 1973-07-24
CA982530A (en) * 1972-05-23 1976-01-27 Roger Grenetier Device for storing and packaging materials
DE2703964A1 (de) * 1975-07-08 1978-08-03 Walter Dr Schweckendiek Pharmazeutische zubereitungen zur behandlung von psoriasis
JPS57102852A (en) * 1980-12-19 1982-06-26 Shionogi & Co Ltd Dicarboxylic acid diamide
US4362737A (en) * 1981-04-13 1982-12-07 Schaefer Rolf Transdermal carrier materials
DE3444915A1 (de) * 1984-12-08 1986-06-12 Hoechst Ag, 6230 Frankfurt N-maleyl-phenylalaninalkylester, verfahren zu ihrer herstellung und ihre verwendung zur herstellung von n-fumarylphenylalaninalkylestern
JPS6248656A (ja) * 1985-08-28 1987-03-03 Showa Denko Kk Ｎ−フマリル−ｌ−フエニルアラニンメチルエステル及びその製法
US4730048A (en) * 1985-12-12 1988-03-08 Regents Of The University Of Minnesota Gut-selective opiates

Also Published As

Publication number Publication date
WO1989001930A1 (en) 1989-03-09
DK218189A (da) 1989-07-03
KR890701545A (ko) 1989-12-20
NO891703L (no) 1989-04-25
EP0328634B1 (en) 1995-07-05
AU2423788A (en) 1989-03-31
AU618759B2 (en) 1992-01-09
IL83775A0 (en) 1988-02-29
EP0328634A4 (en) 1991-08-21
FI891986A (fi) 1989-04-26
DE3854121D1 (de) 1995-08-10
ATE124681T1 (de) 1995-07-15
JPH02501072A (ja) 1990-04-12
ZA886097B (en) 1989-06-28
NO891703D0 (no) 1989-04-25
CA1340005C (en) 1998-08-18
DK218189D0 (da) 1989-05-03
IN167848B (fi) 1990-12-29
JPH0745451B2 (ja) 1995-05-17
DE3854121T2 (de) 1996-03-21
FI891986A0 (fi) 1989-04-26
EP0328634A1 (en) 1989-08-23

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Legal Events

Date Code Title Description
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees