IL82629A0 - Substituted 6-hydroxymethyl-carbapenem antibiotics,the preparation thereof and pharmaceutical compositions containing them - Google Patents
Substituted 6-hydroxymethyl-carbapenem antibiotics,the preparation thereof and pharmaceutical compositions containing themInfo
- Publication number
- IL82629A0 IL82629A0 IL82629A IL8262987A IL82629A0 IL 82629 A0 IL82629 A0 IL 82629A0 IL 82629 A IL82629 A IL 82629A IL 8262987 A IL8262987 A IL 8262987A IL 82629 A0 IL82629 A0 IL 82629A0
- Authority
- IL
- Israel
- Prior art keywords
- hydroxymethyl
- substituted
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863617626 DE3617626A1 (de) | 1986-05-26 | 1986-05-26 | Substituierte 6-hydroxymethyl-carbapenem-antibiotika, verfahren zu ihrer herstellung und ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL82629A0 true IL82629A0 (en) | 1987-11-30 |
Family
ID=6301640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL82629A IL82629A0 (en) | 1986-05-26 | 1987-05-22 | Substituted 6-hydroxymethyl-carbapenem antibiotics,the preparation thereof and pharmaceutical compositions containing them |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US4863916A (fr) |
| EP (1) | EP0247431B1 (fr) |
| JP (1) | JPS62283974A (fr) |
| KR (1) | KR870011139A (fr) |
| AT (1) | ATE55132T1 (fr) |
| AU (1) | AU7319087A (fr) |
| DE (2) | DE3617626A1 (fr) |
| DK (1) | DK264687A (fr) |
| FI (1) | FI872265A (fr) |
| HU (1) | HU197009B (fr) |
| IL (1) | IL82629A0 (fr) |
| ZA (1) | ZA873721B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6425779A (en) * | 1987-04-11 | 1989-01-27 | Lederle Japan Ltd | (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative |
| JP2003277390A (ja) * | 2002-03-25 | 2003-10-02 | Takasago Internatl Corp | アゼチジノン化合物の製造方法 |
| KR100599876B1 (ko) * | 2004-08-31 | 2006-07-13 | 한국화학연구원 | 2-아릴메틸아제티딘 카바페넴 유도체 및 그의 제조방법 |
| MX2011001341A (es) | 2008-08-19 | 2011-03-29 | Xenoport Inc | Prodrogas de metil hidrogeno fumarato, sus composiciones farmaceuticas, y metodos de uso. |
| JP2015526476A (ja) | 2012-08-22 | 2015-09-10 | ゼノポート，インコーポレイティド | メチル水素フマレートの経口剤形およびそのプロドラッグ |
| US10945984B2 (en) | 2012-08-22 | 2021-03-16 | Arbor Pharmaceuticals, Llc | Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects |
| US10179118B2 (en) | 2013-03-24 | 2019-01-15 | Arbor Pharmaceuticals, Llc | Pharmaceutical compositions of dimethyl fumarate |
| CN104211666B (zh) * | 2013-05-31 | 2017-11-14 | 中国人民解放军军事医学科学院毒物药物研究所 | 2,3‑环氧丁二酰胺类化合物、其制备方法和用途 |
| WO2014197860A1 (fr) | 2013-06-07 | 2014-12-11 | Xenoport, Inc. | Procédé de production de monométhylfumarate |
| US9421182B2 (en) | 2013-06-21 | 2016-08-23 | Xenoport, Inc. | Cocrystals of dimethyl fumarate |
| JP2016534133A (ja) | 2013-09-06 | 2016-11-04 | ゼノポート，インコーポレイティド | （ｎ，ｎ−ジエチルカルバモイル）メチル メチル（２ｅ）ブト−２−エン−１，４−ジオエートの結晶形態、その合成方法及び使用 |
| US9999672B2 (en) | 2014-03-24 | 2018-06-19 | Xenoport, Inc. | Pharmaceutical compositions of fumaric acid esters |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK165280A (da) * | 1979-04-19 | 1980-10-20 | Merck & Co Inc | Fremgangsmaade til fremstilling af 2- og 6-substituerede 1-carbadethiapen-2-em-3-carboxylsyrer og mellemprodukter til brug ved udoevelse af fremgangsmaaden |
| US4590073A (en) * | 1984-10-22 | 1986-05-20 | Pfizer Inc. | 6-substituted penicillanic acid 1,1-dioxide compounds |
-
1986
- 1986-05-26 DE DE19863617626 patent/DE3617626A1/de not_active Withdrawn
-
1987
- 1987-05-06 US US07/047,371 patent/US4863916A/en not_active Expired - Fee Related
- 1987-05-12 DE DE8787106855T patent/DE3764027D1/de not_active Expired - Lifetime
- 1987-05-12 EP EP19870106855 patent/EP0247431B1/fr not_active Expired - Lifetime
- 1987-05-12 AT AT87106855T patent/ATE55132T1/de not_active IP Right Cessation
- 1987-05-19 AU AU73190/87A patent/AU7319087A/en not_active Abandoned
- 1987-05-22 FI FI872265A patent/FI872265A/fi not_active Application Discontinuation
- 1987-05-22 IL IL82629A patent/IL82629A0/xx unknown
- 1987-05-25 HU HU872329A patent/HU197009B/hu unknown
- 1987-05-25 DK DK264687A patent/DK264687A/da not_active Application Discontinuation
- 1987-05-25 ZA ZA873721A patent/ZA873721B/xx unknown
- 1987-05-26 KR KR870005187A patent/KR870011139A/ko not_active IP Right Cessation
- 1987-05-26 JP JP62127311A patent/JPS62283974A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| US4863916A (en) | 1989-09-05 |
| DK264687D0 (da) | 1987-05-25 |
| EP0247431A1 (fr) | 1987-12-02 |
| FI872265A (fi) | 1987-11-27 |
| DK264687A (da) | 1987-11-27 |
| JPS62283974A (ja) | 1987-12-09 |
| KR870011139A (ko) | 1987-12-21 |
| ATE55132T1 (de) | 1990-08-15 |
| AU7319087A (en) | 1987-12-03 |
| FI872265A0 (fi) | 1987-05-22 |
| HU197009B (en) | 1989-02-28 |
| ZA873721B (en) | 1987-11-20 |
| HUT45058A (en) | 1988-05-30 |
| EP0247431B1 (fr) | 1990-08-01 |
| DE3617626A1 (de) | 1987-12-03 |
| DE3764027D1 (de) | 1990-09-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL76454A (en) | Diarylacetylene derivatives,their preparation and pharmaceutical compositions containing them | |
| NZ236589A (en) | A-nor-steroid-3-carboxylic acid derivatives and pharmaceutical compositions | |
| IL83162A0 (en) | (substituted amino)-5,6,7,8-tetrahydronaphthyl-oxyacetic acids and esters and amides thereof,their preparation and medicaments containing them | |
| IL82629A0 (en) | Substituted 6-hydroxymethyl-carbapenem antibiotics,the preparation thereof and pharmaceutical compositions containing them | |
| ES8402261A1 (es) | Procedimiento para la obtencion de nuevos derivados de omega-ciano-1,omega difenil-aza-alcano. | |
| DE3372287D1 (en) | Process for the preparation of tetrahydropyridines | |
| IL69598A (en) | 2-nitro-1,1-ethenediamines,their preparation and pharmaceutical compositions containing them | |
| ES8802503A1 (es) | Un procedimiento para preparar derivados de oxotiazolidina. | |
| IL78137A (en) | Cephalosporins,their preparation and pharmaceutical compositions containing them | |
| DK225985D0 (da) | Cephalosporiner eller farmaceutisk acceptable salte deraf, deres fremstilling og anvendelse som laegemidler | |
| DE3361789D1 (en) | Cephalosporin derivatives, their preparation and medicaments containing them | |
| IL91813A0 (en) | Pharmaceutical compositions containing stable oxapenem-3-carboxylic acids and their preparation | |
| AU555185B2 (en) | Cephalosporin antibiotics | |
| WO1987004435A3 (fr) | Composes de xanthine | |
| IT1191034B (it) | Composto ad attivita' vasodilatatrice,antiaggregante e ipocolesterolemizzante,procedimento per la sua preparazione e composizione farmaceutiche relative | |
| AU588414B2 (en) | Methionine-substituted 1, 4-dihydropyridines, process for the preparation and their use | |
| HUT44802A (en) | Process for producing pseudo-oligosaccharides and pharmaceutical compositions containing them | |
| NZ221549A (en) | Penicillin derivatives & pharmaceutical compositions | |
| GB2014574A (en) | Lactam Compounds | |
| ZA828237B (en) | A vasodilator compound,process for the preparation thereof and pharmaceutical compositions therefrom | |
| FI934252A (fi) | 1,5,6,7-tetrahydro-4H-indazol-4-oner innehaollande laekemedel, nya 1,5,6,7-tetrahydro-4H-indazol-4-oner och foerfarande foer deras framstaellning | |
| ES8405403A1 (es) | Procedimiento para la obtencion de 1,4-dihidropiridinas | |
| ES8306152A1 (es) | Un procedimiento para la preparacion de nuevos derivados de 7-oxo-1-azabiciclo (3.2.0) hepteno. |