FI872265A0 - Substituerade 6-hydroximetyl-karbapenem-antibiotika, foerfarande foer deras framstaellning och deras anvaendning. - Google Patents

Substituerade 6-hydroximetyl-karbapenem-antibiotika, foerfarande foer deras framstaellning och deras anvaendning.

Info

Publication number
FI872265A0
FI872265A0 FI872265A FI872265A FI872265A0 FI 872265 A0 FI872265 A0 FI 872265A0 FI 872265 A FI872265 A FI 872265A FI 872265 A FI872265 A FI 872265A FI 872265 A0 FI872265 A0 FI 872265A0
Authority
FI
Finland
Prior art keywords
deras
hydroximetyl
substituerade
carbapenem antibiotics
foerfarande foer
Prior art date
Application number
FI872265A
Other languages
English (en)
Other versions
FI872265A (fi
Inventor
Dieter Haebich
Wolfgang Hartwig
Karl Georg Metzger
Hans-Joachim Zeiler
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI872265A0 publication Critical patent/FI872265A0/fi
Publication of FI872265A publication Critical patent/FI872265A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI872265A 1986-05-26 1987-05-22 Substituerade 6-hydroximetyl-karbapenem-antibiotika, foerfarande foer deras framstaellning och deras anvaendning. FI872265A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863617626 DE3617626A1 (de) 1986-05-26 1986-05-26 Substituierte 6-hydroxymethyl-carbapenem-antibiotika, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
FI872265A0 true FI872265A0 (fi) 1987-05-22
FI872265A FI872265A (fi) 1987-11-27

Family

ID=6301640

Family Applications (1)

Application Number Title Priority Date Filing Date
FI872265A FI872265A (fi) 1986-05-26 1987-05-22 Substituerade 6-hydroximetyl-karbapenem-antibiotika, foerfarande foer deras framstaellning och deras anvaendning.

Country Status (12)

Country Link
US (1) US4863916A (fi)
EP (1) EP0247431B1 (fi)
JP (1) JPS62283974A (fi)
KR (1) KR870011139A (fi)
AT (1) ATE55132T1 (fi)
AU (1) AU7319087A (fi)
DE (2) DE3617626A1 (fi)
DK (1) DK264687A (fi)
FI (1) FI872265A (fi)
HU (1) HU197009B (fi)
IL (1) IL82629A0 (fi)
ZA (1) ZA873721B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6425779A (en) * 1987-04-11 1989-01-27 Lederle Japan Ltd (1r,5s,6s)-2-substituted-thio-6-((r)-1-hydroxyethyl)-1-methyl -carbapenem-3-carboxylic acid derivative
JP2003277390A (ja) * 2002-03-25 2003-10-02 Takasago Internatl Corp アゼチジノン化合物の製造方法
KR100599876B1 (ko) * 2004-08-31 2006-07-13 한국화학연구원 2-아릴메틸아제티딘 카바페넴 유도체 및 그의 제조방법
DK2334378T3 (da) 2008-08-19 2014-07-07 Xenoport Inc Prodrugs af methylhydrogenfumarat, farmaceutiske sammensætninger deraf og fremgangsmåder til anvendelse
AU2013305684B2 (en) 2012-08-22 2016-11-24 Xenoport, Inc. Oral dosage forms of methyl hydrogen fumarate and prodrugs thereof
US10945984B2 (en) 2012-08-22 2021-03-16 Arbor Pharmaceuticals, Llc Methods of administering monomethyl fumarate and prodrugs thereof having reduced side effects
WO2014160633A1 (en) 2013-03-24 2014-10-02 Xenoport, Inc. Pharmaceutical compositions of dimethyl fumarate
CN104211666B (zh) * 2013-05-31 2017-11-14 中国人民解放军军事医学科学院毒物药物研究所 2,3‑环氧丁二酰胺类化合物、其制备方法和用途
US9302977B2 (en) 2013-06-07 2016-04-05 Xenoport, Inc. Method of making monomethyl fumarate
WO2014205392A1 (en) 2013-06-21 2014-12-24 Xenoport, Inc. Cocrystals of dimethyl fumarate
TW201516020A (zh) 2013-09-06 2015-05-01 Xenoport Inc (n,n-二乙基胺甲醯基)甲基(2e)丁-2-烯-1,4-二酸甲酯之晶形、合成方法及用途
US9999672B2 (en) 2014-03-24 2018-06-19 Xenoport, Inc. Pharmaceutical compositions of fumaric acid esters

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
US4590073A (en) * 1984-10-22 1986-05-20 Pfizer Inc. 6-substituted penicillanic acid 1,1-dioxide compounds

Also Published As

Publication number Publication date
DK264687D0 (da) 1987-05-25
DE3617626A1 (de) 1987-12-03
JPS62283974A (ja) 1987-12-09
DE3764027D1 (de) 1990-09-06
KR870011139A (ko) 1987-12-21
EP0247431A1 (de) 1987-12-02
US4863916A (en) 1989-09-05
HU197009B (en) 1989-02-28
FI872265A (fi) 1987-11-27
ATE55132T1 (de) 1990-08-15
HUT45058A (en) 1988-05-30
ZA873721B (en) 1987-11-20
AU7319087A (en) 1987-12-03
EP0247431B1 (de) 1990-08-01
IL82629A0 (en) 1987-11-30
DK264687A (da) 1987-11-27

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Legal Events

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Owner name: BAYER AKTIENGESELLSCHAFT