IL82364A - Recombinant expression system for producing alveolar surfactant protein (asp) encoded by human sp-18, human sp-5 or canine sp-5 dna; recombinant asp produced thereby and pharmaceutical compositions containing the recombinant asp - Google Patents

Recombinant expression system for producing alveolar surfactant protein (asp) encoded by human sp-18, human sp-5 or canine sp-5 dna; recombinant asp produced thereby and pharmaceutical compositions containing the recombinant asp

Info

Publication number
IL82364A
IL82364A IL82364A IL8236487A IL82364A IL 82364 A IL82364 A IL 82364A IL 82364 A IL82364 A IL 82364A IL 8236487 A IL8236487 A IL 8236487A IL 82364 A IL82364 A IL 82364A
Authority
IL
Israel
Prior art keywords
asp
recombinant
human
canine
pharmaceutical compositions
Prior art date
Application number
IL82364A
Other languages
English (en)
Other versions
IL82364A0 (en
Original Assignee
California Biotechnology Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Biotechnology Inc filed Critical California Biotechnology Inc
Publication of IL82364A0 publication Critical patent/IL82364A0/xx
Publication of IL82364A publication Critical patent/IL82364A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/785—Alveolar surfactant peptides; Pulmonary surfactant peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Analytical Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
IL82364A 1986-04-30 1987-04-28 Recombinant expression system for producing alveolar surfactant protein (asp) encoded by human sp-18, human sp-5 or canine sp-5 dna; recombinant asp produced thereby and pharmaceutical compositions containing the recombinant asp IL82364A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/857,715 US4933280A (en) 1984-12-11 1986-04-30 Recombinant DNA sequence encoding Alveolar Surfactant Protein

Publications (2)

Publication Number Publication Date
IL82364A0 IL82364A0 (en) 1987-10-30
IL82364A true IL82364A (en) 1993-08-18

Family

ID=25326586

Family Applications (1)

Application Number Title Priority Date Filing Date
IL82364A IL82364A (en) 1986-04-30 1987-04-28 Recombinant expression system for producing alveolar surfactant protein (asp) encoded by human sp-18, human sp-5 or canine sp-5 dna; recombinant asp produced thereby and pharmaceutical compositions containing the recombinant asp

Country Status (14)

Country Link
US (1) US4933280A (fr)
EP (1) EP0251449B1 (fr)
JP (3) JPH0813839B2 (fr)
KR (1) KR880701246A (fr)
AT (1) ATE118035T1 (fr)
AU (1) AU591566B2 (fr)
CA (1) CA1340611C (fr)
DE (1) DE3751033T2 (fr)
DK (1) DK173173B1 (fr)
ES (1) ES2072850T3 (fr)
GR (1) GR3015913T3 (fr)
HK (1) HK1005887A1 (fr)
IL (1) IL82364A (fr)
WO (1) WO1987006588A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3761394A (en) * 1969-12-31 1973-09-25 Texaco Inc Catalytic cracking of naphtha
US5840527A (en) * 1984-12-11 1998-11-24 Byk Gulden Lomberg Chemische Fabrik Gmbh Recombinant alveolar surfactant protein
WO1987002037A1 (fr) * 1985-09-26 1987-04-09 Genetics Institute, Inc. Proteines tensio-actives pulmonaires
US5013720A (en) * 1986-05-06 1991-05-07 Abbott Laboratories SAP-6-Val proteins and methods
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト，ジエフリー　エイ． 肺胞疎水性界面活性物質関連タンパク質
US5260273A (en) * 1988-01-06 1993-11-09 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US5164369A (en) * 1988-01-06 1992-11-17 The Scripps Research Institute Pulmonary surfactant protein and related polypeptide
US6613734B2 (en) 1988-01-06 2003-09-02 The Scripps Research Institute Peptides-containing liposomal surfactants
WO1990001540A1 (fr) * 1988-08-11 1990-02-22 California Biotechnology Inc. Procede et vecteurs de stabilisation de l'expression de proteines heterologues
SE8803713D0 (sv) * 1988-10-18 1988-10-18 Kabigen Ab Biologically active lipoprotein and its use
DE69125750D1 (de) * 1990-05-21 1997-05-28 Abbott Lab Fettsäure-Oberflächenaktives-Lungenprotein Konjate
GB9120005D0 (en) * 1991-09-19 1991-11-06 Wellcome Found Method of administering phospholipid dispersions
US5272252A (en) * 1991-11-04 1993-12-21 Merrell Dow Pharmaceuticals Inc. Synthetic lung surfactant having antioxidant properties
DE4418936A1 (de) * 1994-05-31 1996-02-08 Byk Gulden Lomberg Chem Fab Polypeptid
US6031075A (en) * 1996-02-05 2000-02-29 Children's Hospital Medical Center Mature alveolar SP-B and a process for producing the same
AU6083899A (en) 1999-09-16 2001-04-17 Aventis Behring Gmbh Combination of c1-inh and lung surfactant for the treatment of respiratory disorders
JP4559731B2 (ja) 2001-10-11 2010-10-13 ニコメッド ゲゼルシャフト ミット ベシュレンクテル ハフツング 肺サーファクタントの新規使用
US8236750B2 (en) 2004-08-06 2012-08-07 Nycomed Gmbh Composition comprising a pulmonary surfactant and a TNF-derived peptide
US7951781B2 (en) 2006-11-02 2011-05-31 University Of Iowa Research Foundation Methods and compositions related to PLUNC surfactant polypeptides
CA2744940A1 (fr) 2008-12-10 2010-06-17 Paka Pulmonary Pharmaceuticals, Inc. Procedes et compositions pour la delivrance de medicaments aux poumons

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312860A (en) * 1980-10-24 1982-01-26 Regents Of The University Of California Lung surfactant compositions
US4361509A (en) * 1981-12-14 1982-11-30 Scripps Clinic And Research Foundation Ultrapurification of factor VIII using monoclonal antibodies
US4562003A (en) * 1984-10-26 1985-12-31 California Biotechnology, Inc. Monoclonal antibodies against alveolar surfactant protein
US4659805A (en) * 1984-12-11 1987-04-21 California Biotechnology, Inc. Recombinant alveolar surfactant protein
EP0273916A4 (fr) * 1986-05-06 1989-11-30 Childrens Hosp Medical Center Proteine associee a un agent tensio-actif hydrophobe pulmonaire d'un poids moleculaire de 6000 daltons, et ses multimeres.
JPH01501282A (ja) * 1986-12-08 1989-05-11 ホイツトセツト，ジエフリー　エイ． 肺胞疎水性界面活性物質関連タンパク質

Also Published As

Publication number Publication date
KR880701246A (ko) 1988-07-26
EP0251449A2 (fr) 1988-01-07
EP0251449B1 (fr) 1995-02-01
JPH08188598A (ja) 1996-07-23
IL82364A0 (en) 1987-10-30
DE3751033T2 (de) 1995-08-10
JP2584962B2 (ja) 1997-02-26
AU591566B2 (en) 1989-12-07
JP2766806B2 (ja) 1998-06-18
JPH01500350A (ja) 1989-02-09
ATE118035T1 (de) 1995-02-15
CA1340611C (fr) 1999-06-29
DK151792A (da) 1992-12-17
HK1005887A1 (en) 1999-01-29
DK173173B1 (da) 2000-02-28
JPH0813839B2 (ja) 1996-02-14
AU7480287A (en) 1987-11-24
WO1987006588A1 (fr) 1987-11-05
JPH09117290A (ja) 1997-05-06
US4933280A (en) 1990-06-12
GR3015913T3 (en) 1995-07-31
DE3751033D1 (de) 1995-03-16
EP0251449A3 (en) 1989-04-19
ES2072850T3 (es) 1995-08-01

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