IL81555A0 - Enzymatic process for 3-substituted cephalosporins - Google Patents

Enzymatic process for 3-substituted cephalosporins

Info

Publication number
IL81555A0
IL81555A0 IL81555A IL8155587A IL81555A0 IL 81555 A0 IL81555 A0 IL 81555A0 IL 81555 A IL81555 A IL 81555A IL 8155587 A IL8155587 A IL 8155587A IL 81555 A0 IL81555 A0 IL 81555A0
Authority
IL
Israel
Prior art keywords
beta
substituted
enzymatic process
alpha
substituted cephalosporins
Prior art date
Application number
IL81555A
Other languages
English (en)
Original Assignee
Baldwin Jack Edward
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baldwin Jack Edward filed Critical Baldwin Jack Edward
Publication of IL81555A0 publication Critical patent/IL81555A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
IL81555A 1986-11-17 1987-02-12 Enzymatic process for 3-substituted cephalosporins IL81555A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US93110286A 1986-11-17 1986-11-17

Publications (1)

Publication Number Publication Date
IL81555A0 true IL81555A0 (en) 1987-09-16

Family

ID=25460231

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81555A IL81555A0 (en) 1986-11-17 1987-02-12 Enzymatic process for 3-substituted cephalosporins

Country Status (9)

Country Link
EP (1) EP0268343B1 (de)
JP (1) JPS63129995A (de)
KR (1) KR900002042B1 (de)
AT (1) ATE76662T1 (de)
DE (1) DE3779403D1 (de)
ES (1) ES2042549T3 (de)
GR (1) GR3005189T3 (de)
HU (1) HUT43644A (de)
IL (1) IL81555A0 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
KR100227711B1 (ko) * 1991-10-15 1999-12-01 한스 발터 라벤 7-아미노세팔로스포란산 및 7-아미노데아세틸세팔로스포란산 제조를 위한 신규한 생물학적 공정
PL182509B1 (pl) * 1995-06-02 2002-01-31 Gist Brocades Bv Sposób wytwarzania kwasu 7-aminodezacetoksycefalosporanowego (7-ADCA)
US5731165A (en) * 1995-06-02 1998-03-24 Gist-Brocades, B.V. Process for the production of 7-ADCA via expandase activity on penicillin G
US6383773B2 (en) * 1998-04-23 2002-05-07 Massachusetts Institute Of Technology Penicillin conversion
US10059722B2 (en) * 2012-11-02 2018-08-28 University Of Kansas Cephalosporin derivatives and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4178210A (en) * 1977-03-07 1979-12-11 Massachusetts Institute Of Technology Accellular synthesis of cephalosporins
US4307192A (en) * 1979-05-17 1981-12-22 Massachusetts Institute Of Technology Cell-free synthesis of deacetoxycephalosporin C
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins

Also Published As

Publication number Publication date
EP0268343B1 (de) 1992-05-27
EP0268343A2 (de) 1988-05-25
EP0268343A3 (en) 1990-02-14
ATE76662T1 (de) 1992-06-15
GR3005189T3 (de) 1993-05-24
DE3779403D1 (de) 1992-07-02
KR880006250A (ko) 1988-07-22
HUT43644A (en) 1987-11-30
KR900002042B1 (ko) 1990-03-31
ES2042549T3 (es) 1993-12-16
JPS63129995A (ja) 1988-06-02

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Legal Events

Date Code Title Description
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