ATE164628T1 - L-proline-3-hydroxylase und verfahren zur herstellung von cis-3-hydroxy-l-prolin - Google Patents

L-proline-3-hydroxylase und verfahren zur herstellung von cis-3-hydroxy-l-prolin

Info

Publication number
ATE164628T1
ATE164628T1 AT94113948T AT94113948T ATE164628T1 AT E164628 T1 ATE164628 T1 AT E164628T1 AT 94113948 T AT94113948 T AT 94113948T AT 94113948 T AT94113948 T AT 94113948T AT E164628 T1 ATE164628 T1 AT E164628T1
Authority
AT
Austria
Prior art keywords
proline
hydroxy
cis
hydroxylase
useful
Prior art date
Application number
AT94113948T
Other languages
English (en)
Inventor
Akio Ozaki
Hideo Mori
Takeshi Shibasaki
Katsuhiko Ando
Keiko Ochiai
Shigeru Chiba
Yoichi Uosaki
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE164628T1 publication Critical patent/ATE164628T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pyrrole Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT94113948T 1993-09-07 1994-09-06 L-proline-3-hydroxylase und verfahren zur herstellung von cis-3-hydroxy-l-prolin ATE164628T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22194193 1993-09-07

Publications (1)

Publication Number Publication Date
ATE164628T1 true ATE164628T1 (de) 1998-04-15

Family

ID=16774558

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94113948T ATE164628T1 (de) 1993-09-07 1994-09-06 L-proline-3-hydroxylase und verfahren zur herstellung von cis-3-hydroxy-l-prolin

Country Status (9)

Country Link
EP (1) EP0645457B1 (de)
KR (1) KR100356927B1 (de)
CN (4) CN1184311C (de)
AT (1) ATE164628T1 (de)
DE (1) DE69409320T2 (de)
DK (1) DK0645457T3 (de)
ES (1) ES2115830T3 (de)
GR (1) GR3026604T3 (de)
HK (3) HK1000714A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177762T3 (es) * 1995-03-07 2002-12-16 Kyowa Hakko Kogyo Kk Procedimiento para producir cis-2-hidrixi-l-prolina.
KR100363395B1 (ko) * 2000-04-17 2002-12-02 국방과학연구소 기계적 합금화와 이단계 급속소결에 의한 초미세결정립텅스텐 중합금의 제조방법
CN110804596B (zh) * 2018-08-06 2021-12-28 中国科学院天津工业生物技术研究所 一种新型的脯氨酸3-羟化酶及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190350A1 (de) * 1984-07-31 1986-08-13 NAGAI, Yoshiki Verfahren zur herstellung menschlicher hydroxylase
US5374542A (en) * 1991-08-26 1994-12-20 Kyowa Hakko Kogyo Co., Ltd. Process for producing 4-hydroxy-L-proline

Also Published As

Publication number Publication date
CN1184311C (zh) 2005-01-12
KR950008693A (ko) 1995-04-19
CN1609192A (zh) 2005-04-27
CN1106458A (zh) 1995-08-09
CN1328370C (zh) 2007-07-25
EP0645457A3 (de) 1996-04-17
HK1000714A1 (en) 2000-03-17
CN1375555A (zh) 2002-10-23
KR100356927B1 (ko) 2003-01-24
EP0645457A2 (de) 1995-03-29
CN1085254C (zh) 2002-05-22
DK0645457T3 (da) 1998-12-07
ES2115830T3 (es) 1998-07-01
CN100451107C (zh) 2009-01-14
EP0645457B1 (de) 1998-04-01
DE69409320D1 (de) 1998-05-07
HK1075063A1 (en) 2005-12-02
GR3026604T3 (en) 1998-07-31
DE69409320T2 (de) 1998-11-12
HK1109782A1 (en) 2008-06-20
CN1990855A (zh) 2007-07-04

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee