DE69409320D1 - L-Proline-3-Hydroxylase und Verfahren zur Herstellung von cis-3-Hydroxy-L-Prolin - Google Patents

L-Proline-3-Hydroxylase und Verfahren zur Herstellung von cis-3-Hydroxy-L-Prolin

Info

Publication number
DE69409320D1
DE69409320D1 DE69409320T DE69409320T DE69409320D1 DE 69409320 D1 DE69409320 D1 DE 69409320D1 DE 69409320 T DE69409320 T DE 69409320T DE 69409320 T DE69409320 T DE 69409320T DE 69409320 D1 DE69409320 D1 DE 69409320D1
Authority
DE
Germany
Prior art keywords
proline
hydroxy
cis
hydroxylase
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69409320T
Other languages
English (en)
Other versions
DE69409320T2 (de
Inventor
Akio Ozaki
Hideo Mori
Takeshi Shibasaki
Katsuhiko Ando
Keiko Ochiai
Shigeru Chiba
Yoichi Uosaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Application granted granted Critical
Publication of DE69409320D1 publication Critical patent/DE69409320D1/de
Publication of DE69409320T2 publication Critical patent/DE69409320T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/24—Proline; Hydroxyproline; Histidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
    • C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
    • C12Y114/11002—Procollagen-proline dioxygenase (1.14.11.2), i.e. proline-hydroxylase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69409320T 1993-09-07 1994-09-06 L-Proline-3-Hydroxylase und Verfahren zur Herstellung von cis-3-Hydroxy-L-Prolin Expired - Lifetime DE69409320T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP22194193 1993-09-07

Publications (2)

Publication Number Publication Date
DE69409320D1 true DE69409320D1 (de) 1998-05-07
DE69409320T2 DE69409320T2 (de) 1998-11-12

Family

ID=16774558

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69409320T Expired - Lifetime DE69409320T2 (de) 1993-09-07 1994-09-06 L-Proline-3-Hydroxylase und Verfahren zur Herstellung von cis-3-Hydroxy-L-Prolin

Country Status (9)

Country Link
EP (1) EP0645457B1 (de)
KR (1) KR100356927B1 (de)
CN (4) CN1184311C (de)
AT (1) ATE164628T1 (de)
DE (1) DE69409320T2 (de)
DK (1) DK0645457T3 (de)
ES (1) ES2115830T3 (de)
GR (1) GR3026604T3 (de)
HK (3) HK1000714A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110804596A (zh) * 2018-08-06 2020-02-18 中国科学院天津工业生物技术研究所 一种新型的脯氨酸3-羟化酶及其应用

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2177762T3 (es) * 1995-03-07 2002-12-16 Kyowa Hakko Kogyo Kk Procedimiento para producir cis-2-hidrixi-l-prolina.
KR100363395B1 (ko) * 2000-04-17 2002-12-02 국방과학연구소 기계적 합금화와 이단계 급속소결에 의한 초미세결정립텅스텐 중합금의 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0190350A1 (de) * 1984-07-31 1986-08-13 NAGAI, Yoshiki Verfahren zur herstellung menschlicher hydroxylase
DE69126141T2 (de) * 1991-08-26 1997-08-28 Kyowa Hakko Kogyo Kk Verfahren zur herstellung von 4-hydroxy-l-prolin

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110804596A (zh) * 2018-08-06 2020-02-18 中国科学院天津工业生物技术研究所 一种新型的脯氨酸3-羟化酶及其应用
CN110804596B (zh) * 2018-08-06 2021-12-28 中国科学院天津工业生物技术研究所 一种新型的脯氨酸3-羟化酶及其应用

Also Published As

Publication number Publication date
CN1106458A (zh) 1995-08-09
CN1609192A (zh) 2005-04-27
CN1990855A (zh) 2007-07-04
CN1375555A (zh) 2002-10-23
CN1085254C (zh) 2002-05-22
DK0645457T3 (da) 1998-12-07
GR3026604T3 (en) 1998-07-31
CN1328370C (zh) 2007-07-25
KR950008693A (ko) 1995-04-19
HK1000714A1 (en) 2000-03-17
EP0645457A2 (de) 1995-03-29
KR100356927B1 (ko) 2003-01-24
CN1184311C (zh) 2005-01-12
EP0645457A3 (de) 1996-04-17
CN100451107C (zh) 2009-01-14
DE69409320T2 (de) 1998-11-12
ATE164628T1 (de) 1998-04-15
HK1109782A1 (en) 2008-06-20
HK1075063A1 (en) 2005-12-02
EP0645457B1 (de) 1998-04-01
ES2115830T3 (es) 1998-07-01

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