IL81370A - Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions - Google Patents

Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions

Info

Publication number
IL81370A
IL81370A IL81370A IL8137087A IL81370A IL 81370 A IL81370 A IL 81370A IL 81370 A IL81370 A IL 81370A IL 8137087 A IL8137087 A IL 8137087A IL 81370 A IL81370 A IL 81370A
Authority
IL
Israel
Prior art keywords
compositions
antibodies
pharmaceutical
preparation
treatment
Prior art date
Application number
IL81370A
Other languages
English (en)
Other versions
IL81370A0 (en
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of IL81370A0 publication Critical patent/IL81370A0/xx
Publication of IL81370A publication Critical patent/IL81370A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
IL81370A 1986-02-07 1987-01-23 Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions IL81370A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82800586A 1986-02-07 1986-02-07
US94449586A 1986-12-19 1986-12-19

Publications (2)

Publication Number Publication Date
IL81370A0 IL81370A0 (en) 1987-08-31
IL81370A true IL81370A (en) 1991-06-30

Family

ID=27125154

Family Applications (1)

Application Number Title Priority Date Filing Date
IL81370A IL81370A (en) 1986-02-07 1987-01-23 Pharmaceutical and diagnostic compositions comprising a plurality of human monoclonal antibodies for the treatment of bacterial diseases,methods for the preparation of the compositions and antibodies and kits containing said compositions

Country Status (28)

Country Link
US (2) US5717071A (cg-RX-API-DMAC7.html)
JP (1) JP2645343B2 (cg-RX-API-DMAC7.html)
KR (1) KR870007697A (cg-RX-API-DMAC7.html)
CN (1) CN87102167A (cg-RX-API-DMAC7.html)
AT (1) AT398781B (cg-RX-API-DMAC7.html)
BE (1) BE1000967A5 (cg-RX-API-DMAC7.html)
CA (1) CA1339013C (cg-RX-API-DMAC7.html)
CH (1) CH672072A5 (cg-RX-API-DMAC7.html)
DE (1) DE3703711A1 (cg-RX-API-DMAC7.html)
DK (1) DK63187A (cg-RX-API-DMAC7.html)
ES (1) ES2009140A6 (cg-RX-API-DMAC7.html)
FI (1) FI94489C (cg-RX-API-DMAC7.html)
FR (1) FR2595946B1 (cg-RX-API-DMAC7.html)
GB (1) GB2186592B (cg-RX-API-DMAC7.html)
GR (1) GR870194B (cg-RX-API-DMAC7.html)
HK (1) HK21795A (cg-RX-API-DMAC7.html)
HU (1) HU203583B (cg-RX-API-DMAC7.html)
IE (1) IE59627B1 (cg-RX-API-DMAC7.html)
IL (1) IL81370A (cg-RX-API-DMAC7.html)
IT (1) IT1207589B (cg-RX-API-DMAC7.html)
LU (1) LU86761A1 (cg-RX-API-DMAC7.html)
MX (1) MX9203629A (cg-RX-API-DMAC7.html)
NL (1) NL8700286A (cg-RX-API-DMAC7.html)
NO (1) NO176924C (cg-RX-API-DMAC7.html)
NZ (2) NZ233920A (cg-RX-API-DMAC7.html)
OA (1) OA08477A (cg-RX-API-DMAC7.html)
PT (1) PT84258B (cg-RX-API-DMAC7.html)
SE (1) SE468747B (cg-RX-API-DMAC7.html)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0256713A3 (en) * 1986-08-06 1989-02-15 Merck & Co. Inc. Therapeutic human antipseudomonas aeruginosa antibodies
CA1341375C (en) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions and methods for the treatment and prevention of gram-negative bacterial infections
DE3925161A1 (de) * 1989-03-15 1990-09-27 Boehringer Mannheim Gmbh Monoklonale, gegen eca gerichtete antikoerper und ihre verwendung
WO1990013660A2 (en) * 1989-05-09 1990-11-15 Cetus Corporation Human monoclonal antibodies to sero-specific determinants of gram-negative bacteria
US6315999B1 (en) 1989-08-10 2001-11-13 Solvay, S.A. Pharmaceutical product for the treatment of sepsis
GB8918232D0 (en) * 1989-08-10 1989-09-20 Opal Stephen M Pharmaceutical product for the treatment of septic shock
US20080139789A1 (en) * 1990-10-22 2008-06-12 Henry M. Jackson Foundation For The Advancement Of Military Medicine Isolated Broadly Reactive Opsonic Immunoglobulin for Treating a Pathogenic Coagulase-Negative Staphylococcus Infection
PT635132E (pt) * 1992-03-19 2001-03-30 Henry M Jackson Found Advanc M Anticorpos opsonicos amplamente reactivos que reagem com antigenios de estafilococos comuns
EP0680337A4 (en) * 1993-01-12 1997-07-30 Anthony George Gristina METHODS AND COMPOSITIONS FOR DIRECT APPLICATION WITH HIGH CONCENTRATION OF ANTIBODIES, PRODUCING PASSIVE IMMUNITY.
US5510264A (en) * 1993-09-28 1996-04-23 Insight Biotech Inc. Antibodies which bind meningitis related homologous antigenic sequences
AU3170199A (en) * 1998-04-14 1999-11-08 Chugai Research Institute For Molecular Medicine, Inc. Novel cytokine-like protein
CA2694466A1 (en) * 2007-07-23 2009-01-29 Sanofi Pasteur Limited Immunogenic polypeptides and monoclonal antibodies
US8444983B2 (en) * 2009-03-23 2013-05-21 Quark Pharmaceuticals, Inc. Composition of anti-ENDO180 antibodies and methods of use for the treatment of cancer and fibrotic diseases
JP6046632B2 (ja) 2010-12-03 2016-12-21 サノフィ パストゥール リミテッドＳａｎｏｆｉ Ｐａｓｔｅｕｒ Ｌｉｍｉｔｅｄ 肺炎球菌に対する免疫用組成物
ES2981535T3 (es) * 2015-11-10 2024-10-09 Visterra Inc Conjugados de molécula de anticuerpo-fármaco que se unen específicamente al lipopolisacárido y usos de los mismos
JP7303110B2 (ja) 2017-01-18 2023-07-04 ビステラ， インコーポレイテッド 抗体分子－薬物コンジュゲートおよびその使用
JP2023521319A (ja) 2020-04-03 2023-05-24 ビステラ， インコーポレイテッド 抗体分子－薬物コンジュゲートおよびその使用
US10973908B1 (en) 2020-05-14 2021-04-13 David Gordon Bermudes Expression of SARS-CoV-2 spike protein receptor binding domain in attenuated salmonella as a vaccine

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4464465A (en) * 1982-04-05 1984-08-07 Genetic Systems Corporation Cell-driven viral transfer in eukaryotes
CA1262238A (en) * 1982-09-30 1989-10-10 Richard Insel Human monoclonal antibodies against bacterial toxins
US4587121A (en) * 1983-06-14 1986-05-06 Miles Laboratories, Inc. High titer Pseudomonas immune serum globulin
US5179018A (en) * 1983-10-14 1993-01-12 Centocor, Inc. Mamalian monoclonal antibodies against endotoxin of gram-negative bacteria
US4834975A (en) * 1984-05-25 1989-05-30 Genetics Corporation Human monoclonal antibodies to serotypic lipopolysaccharide determinants on gram-negative bacteria and their production
DE3426903A1 (de) * 1984-07-20 1986-01-23 Biotest Pharma GmbH, 6000 Frankfurt Eine immunglobulinpraeparation in kombination mit einer anderen pharmakologisch wirksamen praeparation zur verwendung bei der behandlung von krankheiten
US4675287A (en) * 1984-07-26 1987-06-23 Scripps Clinic And Research Foundation Monoclonal antibody directed to human ganglioside GD2
US4677070A (en) * 1985-04-26 1987-06-30 Cetus Corporation Pseudomonas aeruginosa exotoxin A antibodies, their preparation and use
US4772464A (en) * 1985-08-01 1988-09-20 Miles Laboratories, Inc. Protective antibodies to serotypic determinants of flagellar antigens
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
US4777136A (en) * 1985-09-27 1988-10-11 The Regents Of The University Of California Monoclonal antibody reactive with Pseudomonas Aeruginosa
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
US4970070A (en) * 1986-02-07 1990-11-13 Genetic Systems Corporation Protective monoclonal antibody compositions for infections due to group B streptococcus

Also Published As

Publication number Publication date
SE468747B (sv) 1993-03-15
FR2595946A1 (fr) 1987-09-25
IL81370A0 (en) 1987-08-31
JPS62270535A (ja) 1987-11-24
KR870007697A (ko) 1987-09-21
BE1000967A5 (fr) 1989-05-30
IE59627B1 (en) 1994-03-09
PT84258B (pt) 1989-09-14
GR870194B (en) 1987-06-10
US5717071A (en) 1998-02-10
IT8719292A0 (it) 1987-02-06
AT398781B (de) 1995-01-25
NO176924B (no) 1995-03-13
FI94489B (fi) 1995-06-15
HUT46062A (en) 1988-09-28
ATA26287A (de) 1994-06-15
FI870502L (fi) 1987-08-08
FI870502A0 (fi) 1987-02-06
GB8702689D0 (en) 1987-03-11
OA08477A (fr) 1988-07-29
DK63187A (da) 1987-08-08
NL8700286A (nl) 1987-09-01
NO870476L (no) 1987-08-10
DE3703711C2 (cg-RX-API-DMAC7.html) 1993-06-24
NZ219187A (en) 1990-12-21
SE8700467D0 (sv) 1987-02-06
GB2186592A (en) 1987-08-19
DK63187D0 (da) 1987-02-06
CH672072A5 (cg-RX-API-DMAC7.html) 1989-10-31
CA1339013C (en) 1997-03-25
HU203583B (en) 1991-08-28
MX9203629A (es) 1992-07-01
US5837541A (en) 1998-11-17
CN87102167A (zh) 1988-02-03
NZ233920A (en) 1990-12-21
NO176924C (no) 1995-06-21
HK21795A (en) 1995-02-24
SE8700467L (sv) 1987-08-08
ES2009140A6 (es) 1989-09-01
IE870320L (en) 1987-08-07
GB2186592B (en) 1990-08-01
FR2595946B1 (fr) 1991-10-04
FI94489C (fi) 1995-09-25
PT84258A (en) 1987-03-01
LU86761A1 (fr) 1987-09-15
NO870476D0 (no) 1987-02-06
DE3703711A1 (de) 1987-09-24
JP2645343B2 (ja) 1997-08-25
IT1207589B (it) 1989-05-25

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