IL81081A - Topical pharmaceutical compositions for promoting wound healing containing synthetic polysulfated mono-and disaccharides - Google Patents
Topical pharmaceutical compositions for promoting wound healing containing synthetic polysulfated mono-and disaccharidesInfo
- Publication number
- IL81081A IL81081A IL81081A IL8108186A IL81081A IL 81081 A IL81081 A IL 81081A IL 81081 A IL81081 A IL 81081A IL 8108186 A IL8108186 A IL 8108186A IL 81081 A IL81081 A IL 81081A
- Authority
- IL
- Israel
- Prior art keywords
- disaccharides
- preferred
- mono
- salts
- pharmaceutical compositions
- Prior art date
Links
- 150000002016 disaccharides Chemical class 0.000 title abstract 2
- 150000002772 monosaccharides Chemical class 0.000 title abstract 2
- 230000001737 promoting effect Effects 0.000 title 1
- 239000012049 topical pharmaceutical composition Substances 0.000 title 1
- 230000029663 wound healing Effects 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 3
- 150000003839 salts Chemical class 0.000 abstract 3
- 102000008186 Collagen Human genes 0.000 abstract 1
- 108010035532 Collagen Proteins 0.000 abstract 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
- 206010052428 Wound Diseases 0.000 abstract 1
- 208000027418 Wounds and injury Diseases 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- -1 alkali metal salts Chemical class 0.000 abstract 1
- 229920001436 collagen Polymers 0.000 abstract 1
- 239000000499 gel Substances 0.000 abstract 1
- 230000035876 healing Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 229920001542 oligosaccharide Polymers 0.000 abstract 1
- 150000002482 oligosaccharides Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
- WEPNHBQBLCNOBB-FZJVNAOYSA-N sucrose octasulfate Chemical compound OS(=O)(=O)O[C@@H]1[C@H](OS(O)(=O)=O)[C@H](COS(=O)(=O)O)O[C@]1(COS(O)(=O)=O)O[C@@H]1[C@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H](OS(O)(=O)=O)[C@@H](COS(O)(=O)=O)O1 WEPNHBQBLCNOBB-FZJVNAOYSA-N 0.000 abstract 1
- QAOWNCQODCNURD-UHFFFAOYSA-L sulfate group Chemical group S(=O)(=O)([O-])[O-] QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81324385A | 1985-12-24 | 1985-12-24 | |
| US91419286A | 1986-10-01 | 1986-10-01 | |
| US06/922,358 US4912093A (en) | 1986-10-01 | 1986-10-23 | Use of synthetic sulfated saccharides to enhance wound healing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL81081A0 IL81081A0 (en) | 1987-03-31 |
| IL81081A true IL81081A (en) | 1991-08-16 |
Family
ID=27420088
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL81081A IL81081A (en) | 1985-12-24 | 1986-12-23 | Topical pharmaceutical compositions for promoting wound healing containing synthetic polysulfated mono-and disaccharides |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP0230023B1 (de) |
| AT (1) | ATE80038T1 (de) |
| AU (1) | AU607690B2 (de) |
| CA (1) | CA1292185C (de) |
| DE (1) | DE3686645T2 (de) |
| ES (1) | ES2005852A6 (de) |
| IL (1) | IL81081A (de) |
| NZ (1) | NZ218732A (de) |
| PH (1) | PH24823A (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4945084A (en) * | 1987-07-08 | 1990-07-31 | Norman Oksman | Method and composition for topically treating anorectal or other dermal wounds |
| US5916880A (en) * | 1987-12-21 | 1999-06-29 | Bukh Meditec A/S | Reduction of skin wrinkling using sulphated sugars |
| DK505488D0 (da) * | 1987-12-21 | 1988-09-09 | Bar Shalom Daniel | Middel og anvendelse af samme |
| US5709873A (en) * | 1988-02-26 | 1998-01-20 | Niels Bukh A/S | Method of treating conditions of teeth and their supporting tissue |
| DK505588D0 (da) * | 1988-02-26 | 1988-09-09 | Jesper Hamburger | Middel og anvendelse af samme |
| AU609999B2 (en) * | 1988-06-21 | 1991-05-09 | Marion Laboratories, Inc. | Bismuth (phosph/sulf)ated saccharides |
| US4935406A (en) * | 1988-09-20 | 1990-06-19 | Marion Laboratories, Inc. | Use of bismuth (phosph/sulf)ated saccharides against Camplyobacter-associated gastrointestinal disorders |
| US4918175A (en) * | 1988-06-21 | 1990-04-17 | Marion Laboratories, Inc. | Bismuth (phosph/sulf)ated saccharides |
| US5202311A (en) * | 1988-08-19 | 1993-04-13 | Children's Medical Center Corporation | Stabilized fgf composition |
| US5618798A (en) * | 1989-04-20 | 1997-04-08 | Bar-Shalom; Daniel | Use of sucralfate to treat baldness |
| FR2646604B1 (fr) * | 1989-05-03 | 1994-02-04 | Fabre Medicament Pierre | Composition pour usage externe a base de sucralfate et son procede de preparation |
| US4948883A (en) * | 1989-05-15 | 1990-08-14 | Marion Laboratories, Inc. | Preparation of hydrogen and bismuth (phosph/sulf) ated saccharides |
| GR1000796B (el) * | 1989-08-25 | 1992-12-30 | Bukh Meditec | Μεθοδος θεραπειας καταστασεων των οδοντων & των ιστων στηριξεως αυτων |
| US4940786A (en) * | 1989-10-31 | 1990-07-10 | Marion Laboratories, Inc. | One-pot preparation of bismuth (phosph/sulf)ated saccharides |
| US5298616A (en) * | 1990-10-03 | 1994-03-29 | Hoffmann-La Roche Inc. | Sulfated O-polysaccharide-trehaloses |
| JPH04178328A (ja) * | 1990-11-08 | 1992-06-25 | Unitika Ltd | 血管新生阻害剤 |
| CA2061370A1 (en) * | 1991-03-13 | 1992-09-14 | Markus Hosang | Pharmaceutical preparations |
| IL102758A (en) * | 1991-08-23 | 1997-03-18 | Akzo Nv | Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them |
| GB9205800D0 (en) * | 1992-03-17 | 1992-04-29 | British Tech Group | Treatment of fibrotic disorders |
| WO1994022885A1 (en) * | 1993-03-29 | 1994-10-13 | Queen's University At Kingston | Anticoagulant compounds |
| CN102080070B (zh) | 1995-03-17 | 2016-01-20 | 诺沃奇梅兹有限公司 | 新的内切葡聚糖酶 |
| DE69740176D1 (de) | 1996-03-01 | 2011-05-26 | Novo Nordisk As | Appetithemmendes Peptid, Zusammensetzung und Verwendung |
| US6184196B1 (en) | 1998-05-27 | 2001-02-06 | University Of Iowa Research Foundation | Sucrose based surfactants and methods thereof |
| US6838480B1 (en) * | 1999-05-28 | 2005-01-04 | Marie Madeline Wharton | Composition containing sucrafate and a topical anesthetic for humans and animals and method of use thereof |
| EP1404713A4 (de) | 2001-05-24 | 2004-09-22 | Human Dna Technology Inc | Neues keratinocyte growth factor 2 analogon in haarfollikeln |
| ITMI20012188A1 (it) * | 2001-10-19 | 2003-04-19 | Interalta S R L | Sali d'argento del saccarosio - ottosolfato |
| CN102250861A (zh) | 2004-02-13 | 2011-11-23 | 诺维信公司 | 蛋白酶变体 |
| US20090215717A1 (en) * | 2004-08-05 | 2009-08-27 | Ivax Drug Research Institute Ltd. | Sulfated oligosaccharides |
| CA2604222A1 (en) | 2005-04-18 | 2006-10-26 | Novo Nordisk A/S | Il-21 variants |
| EP2406282A1 (de) | 2009-03-11 | 2012-01-18 | Novo Nordisk A/S | Interleukin-21-varianten mit antagonistischer bindung an den il-21-rezeptor |
| FR2953522B1 (fr) | 2009-12-07 | 2012-03-09 | Fabre Pierre Dermo Cosmetique | Sucrose octasulfates de zinc, leur preparation et leurs applications pharmaceutiques et cosmetiques |
| FR2956322A1 (fr) * | 2010-02-17 | 2011-08-19 | Urgo Lab | Utilisation d'oligosaccharides polysulfates synthetiques comme agents de detersion d'une plaie. |
| FR2975994B1 (fr) | 2011-05-31 | 2015-03-06 | Fabre Pierre Dermo Cosmetique | Sucroses octasulfates de calcium, leur preparation et leurs applications pharmaceutiques et cosmetiques |
| FR2975993B1 (fr) | 2011-05-31 | 2013-06-28 | Fabre Pierre Dermo Cosmetique | Sucroses octasulfates de magnesium, leur preparation et leurs applications pharmaceutiques et cosmetiques |
| FR2977798B1 (fr) * | 2011-07-13 | 2016-07-29 | Urgo Lab | Utilisation de composes oligosaccharidiques pour la prevention et le traitement des cicatrices pathologiques |
| FR2991876B1 (fr) | 2012-06-13 | 2014-11-21 | Vivacy Lab | Composition, en milieu aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate |
| FR2993182B1 (fr) | 2012-07-13 | 2014-10-17 | Urgo Lab | Pansement a liberation prolongee d'actifs |
| FR2993781B1 (fr) | 2012-07-30 | 2014-11-28 | Fabre Pierre Dermo Cosmetique | Composition d'un sucrose-octasulfate et d'un emollient |
| FR3043556B1 (fr) * | 2015-11-17 | 2020-01-10 | Urgo Recherche Innovation Et Developpement | Utilisation de composes oligosaccharidiques pour activer l'angiogenese |
| FR3044555B1 (fr) | 2015-12-07 | 2020-03-06 | Centre National De La Recherche Scientifique - Cnrs - | Film comprenant un oligosaccharide polysulfate et un polycation et son procede de fabrication |
| FR3060392B1 (fr) * | 2016-12-19 | 2019-07-12 | Urgo Recherche Innovation Et Developpement | Utilisation de composes oligosaccharidiques pour activer l'epidermisation |
| EP3708151A1 (de) * | 2019-03-15 | 2020-09-16 | Technische Universität Wien | Verfahren zur herstellung einer zusammensetzung mit archäischen lipiden aus einer sulfolobus-zellkultur |
| CN114437148B (zh) * | 2020-11-03 | 2023-12-01 | 江苏开元药业有限公司 | 一种药用辅料的钠盐或钾盐的制备方法 |
| CN114436858A (zh) * | 2020-11-03 | 2022-05-06 | 江苏开元药业有限公司 | 一种药用辅料的三乙胺盐的制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1110939A (en) * | 1965-10-06 | 1968-04-24 | Meito Sangyo Kk | Sulphuric acid esters of disaccharides and hexitols,and their use as antipeptic ulcer agents |
| GB1381426A (en) * | 1973-04-10 | 1975-01-22 | Chugai Pharmaceutical Co Ltd | Method of treating mammals and composition comprising oligosaccha ride sulphuric acid esters and nonionic surface active agents |
| US4098995A (en) * | 1976-07-12 | 1978-07-04 | American Cyanamid Company | Polygalactosido-sucrose poly(h-)sulfate salts |
| US4539198A (en) * | 1983-07-07 | 1985-09-03 | Rowell Laboratories, Inc. | Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range |
-
1986
- 1986-12-18 AU AU66720/86A patent/AU607690B2/en not_active Ceased
- 1986-12-19 EP EP86117762A patent/EP0230023B1/de not_active Expired
- 1986-12-19 DE DE8686117762T patent/DE3686645T2/de not_active Expired - Fee Related
- 1986-12-19 NZ NZ218732A patent/NZ218732A/xx unknown
- 1986-12-19 AT AT86117762T patent/ATE80038T1/de not_active IP Right Cessation
- 1986-12-23 IL IL81081A patent/IL81081A/xx not_active IP Right Cessation
- 1986-12-23 PH PH34659A patent/PH24823A/en unknown
- 1986-12-23 ES ES8603572A patent/ES2005852A6/es not_active Expired
- 1986-12-23 CA CA000526118A patent/CA1292185C/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA1292185C (en) | 1991-11-19 |
| IL81081A0 (en) | 1987-03-31 |
| EP0230023B1 (de) | 1992-09-02 |
| DE3686645T2 (de) | 1993-04-15 |
| ES2005852A6 (es) | 1989-04-01 |
| EP0230023A3 (en) | 1988-11-17 |
| ATE80038T1 (de) | 1992-09-15 |
| AU607690B2 (en) | 1991-03-14 |
| AU6672086A (en) | 1987-06-25 |
| DE3686645D1 (de) | 1992-10-08 |
| NZ218732A (en) | 1989-09-27 |
| PH24823A (en) | 1990-10-30 |
| EP0230023A2 (de) | 1987-07-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |