ES2005852A6 - Metodo para fabricar composiciones farmaceuticas a base de oligosacaridos sulfatados sinteticos. - Google Patents

Metodo para fabricar composiciones farmaceuticas a base de oligosacaridos sulfatados sinteticos.

Info

Publication number
ES2005852A6
ES2005852A6 ES8603572A ES8603572A ES2005852A6 ES 2005852 A6 ES2005852 A6 ES 2005852A6 ES 8603572 A ES8603572 A ES 8603572A ES 8603572 A ES8603572 A ES 8603572A ES 2005852 A6 ES2005852 A6 ES 2005852A6
Authority
ES
Spain
Prior art keywords
preferred
salts
enhancement
pharmaceutical compositions
wound healing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8603572A
Other languages
English (en)
Inventor
Dov Michaeli
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marion Laboratories Inc
Original Assignee
Marion Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/922,358 external-priority patent/US4912093A/en
Application filed by Marion Laboratories Inc filed Critical Marion Laboratories Inc
Publication of ES2005852A6 publication Critical patent/ES2005852A6/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7004—Monosaccharides having only carbon, hydrogen and oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

METODO PARA FABRICAR COMPOSICIONES FARMACEUTICAS A BASE DE OLIGOSACARIDOS SULFATADOS SINTETICOS, EN EL QUE SE HACE REACCIONAR AZUFRE-TRIOXIDO DE PIRIDINA CON UN OLIGOSACARIDO PARA FORMAR UN OLIGOSACARIDO POLISULFATADO SINTETICO O SU SAL, SE RECUPERA COMO UN SOLIDO EL OLIGOSACARIDO POLISULFATADO SINTETICO Y SE COMBINA EL PRODUCTO RECUPERADO CON UN VEHICULO FARMACEUTICO EN UNA PROPORCION SUFICIENTE PARA PRODUCIR 0,1 MG A 10,0 MG/ML DEL OLIGOSACARIDO. LAS COMPOSICIONES OBTENIDAS SON UTILES PARA REFORZAR LA CURACION DE HERIDAS.
ES8603572A 1985-12-24 1986-12-23 Metodo para fabricar composiciones farmaceuticas a base de oligosacaridos sulfatados sinteticos. Expired ES2005852A6 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81324385A 1985-12-24 1985-12-24
US91419286A 1986-10-01 1986-10-01
US06/922,358 US4912093A (en) 1986-10-01 1986-10-23 Use of synthetic sulfated saccharides to enhance wound healing

Publications (1)

Publication Number Publication Date
ES2005852A6 true ES2005852A6 (es) 1989-04-01

Family

ID=27420088

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8603572A Expired ES2005852A6 (es) 1985-12-24 1986-12-23 Metodo para fabricar composiciones farmaceuticas a base de oligosacaridos sulfatados sinteticos.

Country Status (9)

Country Link
EP (1) EP0230023B1 (es)
AT (1) ATE80038T1 (es)
AU (1) AU607690B2 (es)
CA (1) CA1292185C (es)
DE (1) DE3686645T2 (es)
ES (1) ES2005852A6 (es)
IL (1) IL81081A (es)
NZ (1) NZ218732A (es)
PH (1) PH24823A (es)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4945084A (en) * 1987-07-08 1990-07-31 Norman Oksman Method and composition for topically treating anorectal or other dermal wounds
US5908836A (en) * 1987-12-21 1999-06-01 Bar-Shalom; Daniel Protecting skin from radiation damage using sulphated sugars
DK505488D0 (da) * 1987-12-21 1988-09-09 Bar Shalom Daniel Middel og anvendelse af samme
US5709873A (en) * 1988-02-26 1998-01-20 Niels Bukh A/S Method of treating conditions of teeth and their supporting tissue
DK505588D0 (da) * 1988-02-26 1988-09-09 Jesper Hamburger Middel og anvendelse af samme
US4935406A (en) * 1988-09-20 1990-06-19 Marion Laboratories, Inc. Use of bismuth (phosph/sulf)ated saccharides against Camplyobacter-associated gastrointestinal disorders
AU609999B2 (en) * 1988-06-21 1991-05-09 Marion Laboratories, Inc. Bismuth (phosph/sulf)ated saccharides
US4918175A (en) * 1988-06-21 1990-04-17 Marion Laboratories, Inc. Bismuth (phosph/sulf)ated saccharides
US5202311A (en) * 1988-08-19 1993-04-13 Children's Medical Center Corporation Stabilized fgf composition
US5618798A (en) * 1989-04-20 1997-04-08 Bar-Shalom; Daniel Use of sucralfate to treat baldness
FR2646604B1 (fr) * 1989-05-03 1994-02-04 Fabre Medicament Pierre Composition pour usage externe a base de sucralfate et son procede de preparation
US4948883A (en) * 1989-05-15 1990-08-14 Marion Laboratories, Inc. Preparation of hydrogen and bismuth (phosph/sulf) ated saccharides
GR1000796B (el) * 1989-08-25 1992-12-30 Bukh Meditec Μεθοδος θεραπειας καταστασεων των οδοντων & των ιστων στηριξεως αυτων
US4940786A (en) * 1989-10-31 1990-07-10 Marion Laboratories, Inc. One-pot preparation of bismuth (phosph/sulf)ated saccharides
US5298616A (en) * 1990-10-03 1994-03-29 Hoffmann-La Roche Inc. Sulfated O-polysaccharide-trehaloses
JPH04178328A (ja) * 1990-11-08 1992-06-25 Unitika Ltd 血管新生阻害剤
CA2061370A1 (en) * 1991-03-13 1992-09-14 Markus Hosang Pharmaceutical preparations
IL102758A (en) * 1991-08-23 1997-03-18 Akzo Nv Glycosaminoglycanoid derivatives, their preparation and pharmaceutical compositions comprising them
GB9205800D0 (en) * 1992-03-17 1992-04-29 British Tech Group Treatment of fibrotic disorders
CA2159649A1 (en) * 1993-03-29 1994-10-13 Queen's University At Kingston Anticoagulant compounds
EP2431462A3 (en) 1995-03-17 2012-05-23 Novozymes A/S Novel endoglucanases
PT1975177E (pt) 1996-03-01 2011-07-26 Novo Nordisk As Peptídeo supressor do apetite, sua composição e uso
EP1088468A2 (en) * 1998-05-27 2001-04-04 Denver Instrument Company A microwave moisture analyzer: apparatus and method
US6838480B1 (en) * 1999-05-28 2005-01-04 Marie Madeline Wharton Composition containing sucrafate and a topical anesthetic for humans and animals and method of use thereof
JP3966819B2 (ja) 2001-05-24 2007-08-29 キム，スーギョン 毛嚢に存在する新規の第２ケラチノサイト成長因子類似体
ITMI20012188A1 (it) * 2001-10-19 2003-04-19 Interalta S R L Sali d'argento del saccarosio - ottosolfato
WO2005078074A2 (en) 2004-02-13 2005-08-25 Novozymes A/S Protease variants
US20090215717A1 (en) * 2004-08-05 2009-08-27 Ivax Drug Research Institute Ltd. Sulfated oligosaccharides
RU2412199C2 (ru) 2005-04-18 2011-02-20 Ново Нордиск А/С Варианты ил-21
EP2406282A1 (en) 2009-03-11 2012-01-18 Novo Nordisk A/S Interleukin-21 variants having antagonistic binding to the il-21 receptor
FR2953522B1 (fr) 2009-12-07 2012-03-09 Fabre Pierre Dermo Cosmetique Sucrose octasulfates de zinc, leur preparation et leurs applications pharmaceutiques et cosmetiques
FR2956322A1 (fr) * 2010-02-17 2011-08-19 Urgo Lab Utilisation d'oligosaccharides polysulfates synthetiques comme agents de detersion d'une plaie.
FR2975994B1 (fr) 2011-05-31 2015-03-06 Fabre Pierre Dermo Cosmetique Sucroses octasulfates de calcium, leur preparation et leurs applications pharmaceutiques et cosmetiques
FR2975993B1 (fr) 2011-05-31 2013-06-28 Fabre Pierre Dermo Cosmetique Sucroses octasulfates de magnesium, leur preparation et leurs applications pharmaceutiques et cosmetiques
FR2977798B1 (fr) * 2011-07-13 2016-07-29 Urgo Lab Utilisation de composes oligosaccharidiques pour la prevention et le traitement des cicatrices pathologiques
FR2991876B1 (fr) 2012-06-13 2014-11-21 Vivacy Lab Composition, en milieu aqueux, comprenant au moins un acide hyaluronique et au moins un sel hydrosoluble de sucrose octasulfate
FR2993182B1 (fr) 2012-07-13 2014-10-17 Urgo Lab Pansement a liberation prolongee d'actifs
FR2993781B1 (fr) * 2012-07-30 2014-11-28 Fabre Pierre Dermo Cosmetique Composition d'un sucrose-octasulfate et d'un emollient
FR3043556B1 (fr) * 2015-11-17 2020-01-10 Urgo Recherche Innovation Et Developpement Utilisation de composes oligosaccharidiques pour activer l'angiogenese
FR3044555B1 (fr) 2015-12-07 2020-03-06 Centre National De La Recherche Scientifique - Cnrs - Film comprenant un oligosaccharide polysulfate et un polycation et son procede de fabrication
FR3060392B1 (fr) * 2016-12-19 2019-07-12 Urgo Recherche Innovation Et Developpement Utilisation de composes oligosaccharidiques pour activer l'epidermisation
CN114436858A (zh) * 2020-11-03 2022-05-06 江苏开元药业有限公司 一种药用辅料的三乙胺盐的制备方法
CN114437148B (zh) * 2020-11-03 2023-12-01 江苏开元药业有限公司 一种药用辅料的钠盐或钾盐的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1110939A (en) * 1965-10-06 1968-04-24 Meito Sangyo Kk Sulphuric acid esters of disaccharides and hexitols,and their use as antipeptic ulcer agents
GB1381426A (en) * 1973-04-10 1975-01-22 Chugai Pharmaceutical Co Ltd Method of treating mammals and composition comprising oligosaccha ride sulphuric acid esters and nonionic surface active agents
US4098995A (en) * 1976-07-12 1978-07-04 American Cyanamid Company Polygalactosido-sucrose poly(h-)sulfate salts
JPS58126898A (ja) * 1982-01-25 1983-07-28 Mihoko Tomiyama 蔗糖ポリ硫酸エステルのアルミニウム塩の製造方法
US4539198A (en) * 1983-07-07 1985-09-03 Rowell Laboratories, Inc. Solid pharmaceutical formulations for slow, zero order release via controlled surface erosion: expanded range

Also Published As

Publication number Publication date
NZ218732A (en) 1989-09-27
EP0230023A2 (en) 1987-07-29
PH24823A (en) 1990-10-30
EP0230023A3 (en) 1988-11-17
DE3686645T2 (de) 1993-04-15
CA1292185C (en) 1991-11-19
EP0230023B1 (en) 1992-09-02
ATE80038T1 (de) 1992-09-15
AU6672086A (en) 1987-06-25
DE3686645D1 (de) 1992-10-08
IL81081A (en) 1991-08-16
AU607690B2 (en) 1991-03-14
IL81081A0 (en) 1987-03-31

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