IL80076A0 - Bacterial methionine n-terminal peptidase and its preparation - Google Patents

Bacterial methionine n-terminal peptidase and its preparation

Info

Publication number
IL80076A0
IL80076A0 IL80076A IL8007686A IL80076A0 IL 80076 A0 IL80076 A0 IL 80076A0 IL 80076 A IL80076 A IL 80076A IL 8007686 A IL8007686 A IL 8007686A IL 80076 A0 IL80076 A0 IL 80076A0
Authority
IL
Israel
Prior art keywords
preparation
bacterial methionine
terminal peptidase
peptidase
terminal
Prior art date
Application number
IL80076A
Other languages
English (en)
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/778,414 external-priority patent/US4870017A/en
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of IL80076A0 publication Critical patent/IL80076A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/30—Signal or leader sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Botany (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
IL80076A 1985-09-20 1986-09-18 Bacterial methionine n-terminal peptidase and its preparation IL80076A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/778,414 US4870017A (en) 1985-09-20 1985-09-20 Bacterial methionine N-terminal peptidase
US06/860,330 US4865974A (en) 1985-09-20 1986-05-06 Bacterial methionine N-terminal peptidase

Publications (1)

Publication Number Publication Date
IL80076A0 true IL80076A0 (en) 1986-12-31

Family

ID=27119447

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80076A IL80076A0 (en) 1985-09-20 1986-09-18 Bacterial methionine n-terminal peptidase and its preparation

Country Status (9)

Country Link
US (1) US4865974A (fi)
EP (1) EP0219237A1 (fi)
JP (1) JP2569218B2 (fi)
AU (1) AU596810B2 (fi)
CA (1) CA1338642C (fi)
DK (1) DK448286A (fi)
FI (1) FI863797A (fi)
IL (1) IL80076A0 (fi)
NO (1) NO863596L (fi)

Families Citing this family (46)

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Publication number Priority date Publication date Assignee Title
DK55685A (da) * 1985-02-07 1986-08-08 Nordisk Gentofte Enzym eller enzymkompleks med proteolytisk aktivitet
US5013662A (en) * 1985-09-20 1991-05-07 Cetus Corporation Bacterial methionine n-terminal peptidase
DE3541856A1 (de) * 1985-11-27 1987-06-04 Hoechst Ag Eukaryotische fusionsproteine, ihre herstellung und verwendung sowie mittel zur durchfuehrung des verfahrens
GB8703015D0 (en) * 1987-02-10 1987-03-18 Biogen Nv Aminopeptidase
DE3811921A1 (de) * 1988-04-09 1989-10-19 Hoechst Ag Verfahren zur herstellung von proteinen, die n-terminal mit prolin beginnen
AU4057889A (en) * 1988-08-26 1990-03-23 General Hospital Corporation, The Isolation, purification, and characterization of the methionine-specific aminopeptidases: mas i and mas x
AU4221089A (en) * 1988-09-13 1990-04-02 General Hospital Corporation, The Isolation, purification, and characterization of the aminopeptidases: ap2, ap1, and apx
AU4188189A (en) * 1988-09-13 1990-04-02 General Hospital Corporation, The Isolation, purification, and characterization of the aminopeptidases: mas ii and mas iii
KR900702014A (ko) * 1988-09-13 1990-12-05 원본미기재 아미노펩티다아제 ap1 및 ap122의 단리, 정제 및 특성확인
US5126249A (en) * 1989-05-09 1992-06-30 Eli Lilly And Company Enzymatic removal of a protein amino-terminal sequence
ES2109336T3 (es) 1990-11-26 1998-01-16 Genetics Inst Expresion de pace en celulas huesped y metodos de utilizacion de la misma.
DE69233710T2 (de) * 1991-07-24 2008-06-19 Novartis Ag Expressionsvektor für Prolylendopeptidase von Flavobacterium meningosepticum
GB9225021D0 (en) * 1992-11-30 1993-01-20 Sandoz Ltd Organic compounds
US5616485A (en) * 1993-12-23 1997-04-01 Cangene Corporation Streptomyces proteases and improved streptomyces strains for expression of peptides and polypeptides
US6127144A (en) * 1993-12-23 2000-10-03 Cangene Corporation Method for expression of proteins in bacterial host cells
US5629167A (en) 1994-04-19 1997-05-13 Biocine S.P.A. Detection of antibodies against Chlamydia trachomatis pgp3 antigen in patient sera by enzyme-linked immunosorbent assay
US5753465A (en) * 1994-08-30 1998-05-19 Carnegie Mellon University Unmodified recombinant human adult hemoglobin production
NO944411L (no) * 1994-11-17 1996-05-20 Leiv Sigve Haavarstein Endoprotease med en ny spaltningsspesifisitet
US5843888A (en) * 1995-05-01 1998-12-01 Carnegie Mellon University Low oxygen affinity mutant hemoglobin
US5885820A (en) * 1996-01-31 1999-03-23 St. Louis University Clone of a nucleotide sequence encoding a protein having two functions
KR100369839B1 (ko) * 1997-02-28 2003-06-12 주식회사 엘지생명과학 바실러스리케니포미스균주에서유래한아미노펩티다제,그의제조방법및이를이용한천연형단백질의제조방법
CA2308606A1 (en) 1997-11-06 1999-05-20 Chiron S.P.A. Neisserial antigens
AU1979599A (en) 1998-01-14 1999-08-02 Chiron S.P.A. (neisseria meningitidis) antigens
GB9808932D0 (en) 1998-04-27 1998-06-24 Chiron Spa Polyepitope carrier protein
BR9910089A (pt) 1998-05-01 2004-06-08 Chiron Corp Composições e antìgenos de neisseria meningitidis
RU2245366C2 (ru) 1999-04-30 2005-01-27 Чирон С.Р.Л. Антиген neisseria, кодирующая его нуклеиновая кислота, их использование
GB9911683D0 (en) 1999-05-19 1999-07-21 Chiron Spa Antigenic peptides
GB9916529D0 (en) 1999-07-14 1999-09-15 Chiron Spa Antigenic peptides
EP2275552B1 (en) 1999-10-29 2015-09-09 GlaxoSmithKline Biologicals SA Neisserial antigenic peptides
PT2289545T (pt) 2000-01-17 2016-09-06 Glaxosmithkline Biologicals Sa Vacina de omv suplementada contra meningococos
US7816098B2 (en) * 2000-01-31 2010-10-19 Sense Proteomic Limited Methods of making and using a protein array
MXPA03003690A (es) 2000-10-27 2004-05-05 Chiron Spa Acidos nucleicos y proteinas de los grupos a y b de estreptococos.
GB0107661D0 (en) 2001-03-27 2001-05-16 Chiron Spa Staphylococcus aureus
GB0107658D0 (en) 2001-03-27 2001-05-16 Chiron Spa Streptococcus pneumoniae
WO2003010194A2 (en) 2001-07-27 2003-02-06 Chiron Srl. Meningococcus adhesins nada, app and orf 40
PL206286B1 (pl) * 2001-09-13 2010-07-30 Genentech Incgenentech Inc Komórka Gram-ujemnej bakterii, sposób wytwarzania heterologicznego peptydu, sposób zapobiegania odcinaniu N-końcowego aminokwasu, sposób odcinania N-końcowego aminokwasu i sposób wytwarzania skróconego polipeptydu
ES2312649T3 (es) 2001-12-12 2009-03-01 Novartis Vaccines And Diagnostics S.R.L. Inmunizacion frente a chlamydia trachomatis.
EP2279746B1 (en) 2002-11-15 2013-10-02 Novartis Vaccines and Diagnostics S.r.l. Surface proteins in neisseria meningitidis
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
GB0308198D0 (en) 2003-04-09 2003-05-14 Chiron Srl ADP-ribosylating bacterial toxin
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
US20110206692A1 (en) 2006-06-09 2011-08-25 Novartis Ag Conformers of bacterial adhesins
NZ587382A (en) 2008-02-21 2012-01-12 Novartis Ag Meningococcal fhbp polypeptides
KR101041986B1 (ko) 2008-03-06 2011-06-16 (주)한국비엠아이 인간 인터루킨-2의 대량 생산을 위한 신규한 균주
WO2011024072A2 (en) 2009-08-27 2011-03-03 Novartis Ag Hybrid polypeptides including meningococcal fhbp sequences
BR112012010531A2 (pt) 2009-10-27 2019-09-24 Novartis Ag "polipeptídeos de modificação meningocócica fhbp"

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL60184A (en) * 1979-05-31 1984-05-31 Schering Ag Process for the specific cleavage of protein sequences from proteins
US4350764A (en) * 1980-03-10 1982-09-21 The Regents Of The University Of California Microbiological synthesis of beta endorphin
US4338397A (en) * 1980-04-11 1982-07-06 President And Fellows Of Harvard College Mature protein synthesis
US4755465A (en) * 1983-04-25 1988-07-05 Genentech, Inc. Secretion of correctly processed human growth hormone in E. coli and Pseudomonas
DE3327007A1 (de) * 1983-07-27 1985-02-07 Hoechst Ag, 6230 Frankfurt Herstellung von polypeptiden mit einem saeureamid-carboxyterminus
JPS6041697A (ja) * 1983-08-15 1985-03-05 Asahi Chem Ind Co Ltd 活性蛋白質誘導体の新規合成法
DE122004000009I1 (de) * 1984-08-16 2004-11-18 Savient Pharmaceuticals Inc Methode zur Herstellung von menschlichen Wachstumshormonen.

Also Published As

Publication number Publication date
DK448286A (da) 1987-03-21
JP2569218B2 (ja) 1997-01-08
CA1338642C (en) 1996-10-15
FI863797A (fi) 1987-03-21
AU6294486A (en) 1987-03-26
NO863596L (no) 1987-03-23
US4865974A (en) 1989-09-12
AU596810B2 (en) 1990-05-17
DK448286D0 (da) 1986-09-18
NO863596D0 (no) 1986-09-09
FI863797A0 (fi) 1986-09-19
EP0219237A1 (en) 1987-04-22
JPH03277287A (ja) 1991-12-09

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