IL78910A0 - Anti-cancer quinazoline derivatives - Google Patents
Anti-cancer quinazoline derivativesInfo
- Publication number
- IL78910A0 IL78910A0 IL78910A IL7891086A IL78910A0 IL 78910 A0 IL78910 A0 IL 78910A0 IL 78910 A IL78910 A IL 78910A IL 7891086 A IL7891086 A IL 7891086A IL 78910 A0 IL78910 A0 IL 78910A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- heteroatom
- quinazoline derivatives
- halogeno
- chem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858513754A GB8513754D0 (en) | 1985-05-31 | 1985-05-31 | Anti-cancer quinazoline derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
IL78910A0 true IL78910A0 (en) | 1986-09-30 |
Family
ID=10579966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL78910A IL78910A0 (en) | 1985-05-31 | 1986-05-26 | Anti-cancer quinazoline derivatives |
Country Status (17)
Country | Link |
---|---|
US (1) | US5236927A (pt) |
EP (1) | EP0204529B1 (pt) |
JP (1) | JPS61282368A (pt) |
AT (1) | ATE87621T1 (pt) |
AU (1) | AU592271B2 (pt) |
DE (1) | DE3688150T2 (pt) |
DK (1) | DK255786A (pt) |
ES (1) | ES8800911A1 (pt) |
FI (1) | FI862303A (pt) |
GB (2) | GB8513754D0 (pt) |
GR (1) | GR861418B (pt) |
HU (1) | HUT45512A (pt) |
IL (1) | IL78910A0 (pt) |
NO (1) | NO862170L (pt) |
NZ (1) | NZ216363A (pt) |
PT (1) | PT82682B (pt) |
ZA (1) | ZA864051B (pt) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
GB8707053D0 (en) * | 1987-03-25 | 1987-04-29 | Ici Plc | Anti-tumour agents |
US4857530A (en) * | 1987-11-03 | 1989-08-15 | Warner-Lambert Company | Substituted quinazolinones as anticancer agents |
GB8809978D0 (en) * | 1988-04-27 | 1988-06-02 | Ici Plc | Anti-tumour agents |
EP0365763A1 (en) * | 1988-09-30 | 1990-05-02 | Agouron Pharmaceuticals, Inc. | Antiproliferative cyclic compounds |
US5286726A (en) * | 1990-04-12 | 1994-02-15 | The Regents Of The University Of Michigan | Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases |
GB9013615D0 (en) | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
US6762188B1 (en) | 1990-06-19 | 2004-07-13 | Smithkline Beecham Corporation | Pharmaceutically active benzoquinazoline compounds |
GB9105771D0 (en) * | 1991-03-19 | 1991-05-01 | Cancer Res Inst Royal | Anti-cancer compounds |
GB9205320D0 (en) * | 1992-03-11 | 1992-04-22 | Ici Plc | Anti-tumour compounds |
GB9205907D0 (en) * | 1992-03-18 | 1992-04-29 | Cancer Res Inst Royal | Anti-cancer compounds |
US5430148A (en) * | 1992-03-31 | 1995-07-04 | Agouron Pharmaceuticals, Inc. | Antiproliferative quinazolines |
GB9223352D0 (en) * | 1992-11-06 | 1992-12-23 | Ici Plc | Tricyclic compounds |
US7262058B2 (en) * | 2001-03-09 | 2007-08-28 | Nonda Katopodis | Method for determining lipid associated sialoprotein in body fluids |
KR20050061545A (ko) * | 2002-10-18 | 2005-06-22 | 코닌클리케 필립스 일렉트로닉스 엔.브이. | Tv-애니타임의 메타데이터 보호를 위한 방법 및 시스템 |
CA2502302A1 (en) * | 2002-11-04 | 2004-05-21 | Nps Pharmaceuticals, Inc. | Quinazolinone compounds as calcilytics |
WO2007011618A1 (en) * | 2005-07-15 | 2007-01-25 | Schering Corporation | Quinazoline derivatives useful in cancer treatment |
CA2615380A1 (en) * | 2005-07-15 | 2007-01-25 | Schering Corporation | Quinazoline derivatives useful in cancer treatment |
CN101547922B (zh) | 2006-10-04 | 2012-06-20 | 辉瑞产品公司 | 作为钙受体拮抗剂的吡啶并[4,3-d]嘧啶-4(3H)-酮衍生物 |
CA2966280A1 (en) | 2007-10-26 | 2009-04-30 | The Regents Of The University Of California | Diarylhydantoin compounds |
HRP20171415T4 (hr) | 2009-06-25 | 2023-03-03 | Alkermes Pharma Ireland Limited | Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja |
JP6076740B2 (ja) * | 2010-01-07 | 2017-02-08 | アルカーメス ファーマ アイルランド リミテッド | 第四級アンモニウム塩プロドラッグ |
EP2585066B1 (en) | 2010-06-24 | 2018-09-26 | Alkermes Pharma Ireland Limited | Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
US9034867B2 (en) | 2011-03-18 | 2015-05-19 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising sorbitan esters |
CA2867137C (en) | 2012-03-19 | 2020-12-08 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising aripiprazole prodrugs and benzyl alcohol |
JP6219918B2 (ja) | 2012-03-19 | 2017-10-25 | アルカームス ファーマ アイルランド リミテッド | グリセロールエステルを含む医薬組成物 |
JP6471089B2 (ja) | 2012-03-19 | 2019-02-13 | アルカームス ファーマ アイルランド リミテッド | 脂肪酸エステルを含む医薬組成物 |
ES2792149T3 (es) | 2012-09-19 | 2020-11-10 | Alkermes Pharma Ireland Ltd | Composiciones farmacéuticas que tienen estabilidad de almacenamiento mejorada |
MX2016012041A (es) | 2014-03-20 | 2017-01-19 | Alkermes Pharma Ireland Ltd | Formulaciones de aripiprazol que tienen mayores velocidades de inyeccion. |
JP7384812B2 (ja) | 2018-03-05 | 2023-11-21 | アルカームス ファーマ アイルランド リミテッド | アリピプラゾール投与戦略 |
WO2024028999A1 (ja) * | 2022-08-03 | 2024-02-08 | Ils株式会社 | N-[4-メチルアミノベンゾイル]-l-グルタミン酸ジエチルエステルの製造方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1021196A (en) * | 1964-02-20 | 1966-03-02 | Parke Davis & Co | Novel amino acids and means for producing the same |
US3471498A (en) * | 1967-08-11 | 1969-10-07 | Parke Davis & Co | Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids |
EP0031237B1 (en) | 1979-12-19 | 1984-10-17 | National Research Development Corporation | Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents |
GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
-
1985
- 1985-05-31 GB GB858513754A patent/GB8513754D0/en active Pending
-
1986
- 1986-05-26 IL IL78910A patent/IL78910A0/xx unknown
- 1986-05-30 JP JP61125587A patent/JPS61282368A/ja active Pending
- 1986-05-30 EP EP86304148A patent/EP0204529B1/en not_active Expired - Lifetime
- 1986-05-30 HU HU862288A patent/HUT45512A/hu unknown
- 1986-05-30 AU AU58220/86A patent/AU592271B2/en not_active Ceased
- 1986-05-30 PT PT82682A patent/PT82682B/pt not_active IP Right Cessation
- 1986-05-30 DK DK255786A patent/DK255786A/da not_active Application Discontinuation
- 1986-05-30 ES ES555548A patent/ES8800911A1/es not_active Expired
- 1986-05-30 GB GB08613184A patent/GB2175903B/en not_active Expired
- 1986-05-30 NZ NZ216363A patent/NZ216363A/xx unknown
- 1986-05-30 AT AT86304148T patent/ATE87621T1/de not_active IP Right Cessation
- 1986-05-30 ZA ZA864051A patent/ZA864051B/xx unknown
- 1986-05-30 DE DE8686304148T patent/DE3688150T2/de not_active Expired - Fee Related
- 1986-05-30 GR GR861418A patent/GR861418B/el unknown
- 1986-05-30 FI FI862303A patent/FI862303A/fi not_active Application Discontinuation
- 1986-05-30 NO NO862170A patent/NO862170L/no unknown
-
1990
- 1990-12-12 US US07/625,695 patent/US5236927A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
DK255786D0 (da) | 1986-05-30 |
EP0204529A2 (en) | 1986-12-10 |
DE3688150T2 (de) | 1993-07-29 |
EP0204529B1 (en) | 1993-03-31 |
GB2175903B (en) | 1988-10-12 |
ES555548A0 (es) | 1987-12-01 |
PT82682B (pt) | 1988-03-03 |
ATE87621T1 (de) | 1993-04-15 |
GB8513754D0 (en) | 1985-07-03 |
DK255786A (da) | 1986-12-01 |
JPS61282368A (ja) | 1986-12-12 |
NO862170L (no) | 1986-12-01 |
NZ216363A (en) | 1989-07-27 |
DE3688150D1 (de) | 1993-05-06 |
ZA864051B (en) | 1987-01-28 |
FI862303A0 (fi) | 1986-05-30 |
ES8800911A1 (es) | 1987-12-01 |
HUT45512A (en) | 1988-07-28 |
GR861418B (en) | 1986-09-26 |
AU5822086A (en) | 1986-12-04 |
EP0204529A3 (en) | 1987-11-19 |
US5236927A (en) | 1993-08-17 |
PT82682A (en) | 1986-06-01 |
GB8613184D0 (en) | 1986-07-02 |
GB2175903A (en) | 1986-12-10 |
FI862303A (fi) | 1986-12-01 |
AU592271B2 (en) | 1990-01-04 |
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