FI862303A - Foerfarande foer framstaellning av cancer motverkande kinazolinderivater. - Google Patents

Foerfarande foer framstaellning av cancer motverkande kinazolinderivater. Download PDF

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Publication number
FI862303A
FI862303A FI862303A FI862303A FI862303A FI 862303 A FI862303 A FI 862303A FI 862303 A FI862303 A FI 862303A FI 862303 A FI862303 A FI 862303A FI 862303 A FI862303 A FI 862303A
Authority
FI
Finland
Prior art keywords
group
heteroatom
motverkande
kinazolinderivater
cancer
Prior art date
Application number
FI862303A
Other languages
English (en)
Finnish (fi)
Other versions
FI862303A0 (fi
Inventor
Ann Lesley Jackman
David Richard Newell
Terence Richard Jones
Original Assignee
Nat Res Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Res Dev filed Critical Nat Res Dev
Publication of FI862303A0 publication Critical patent/FI862303A0/fi
Publication of FI862303A publication Critical patent/FI862303A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72Quinazolines; Hydrogenated quinazolines
    • C07D239/86Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88Oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI862303A 1985-05-31 1986-05-30 Foerfarande foer framstaellning av cancer motverkande kinazolinderivater. FI862303A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB858513754A GB8513754D0 (en) 1985-05-31 1985-05-31 Anti-cancer quinazoline derivatives

Publications (2)

Publication Number Publication Date
FI862303A0 FI862303A0 (fi) 1986-05-30
FI862303A true FI862303A (fi) 1986-12-01

Family

ID=10579966

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862303A FI862303A (fi) 1985-05-31 1986-05-30 Foerfarande foer framstaellning av cancer motverkande kinazolinderivater.

Country Status (17)

Country Link
US (1) US5236927A (pt)
EP (1) EP0204529B1 (pt)
JP (1) JPS61282368A (pt)
AT (1) ATE87621T1 (pt)
AU (1) AU592271B2 (pt)
DE (1) DE3688150T2 (pt)
DK (1) DK255786A (pt)
ES (1) ES8800911A1 (pt)
FI (1) FI862303A (pt)
GB (2) GB8513754D0 (pt)
GR (1) GR861418B (pt)
HU (1) HUT45512A (pt)
IL (1) IL78910A0 (pt)
NO (1) NO862170L (pt)
NZ (1) NZ216363A (pt)
PT (1) PT82682B (pt)
ZA (1) ZA864051B (pt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents
GB8707053D0 (en) * 1987-03-25 1987-04-29 Ici Plc Anti-tumour agents
US4857530A (en) * 1987-11-03 1989-08-15 Warner-Lambert Company Substituted quinazolinones as anticancer agents
GB8809978D0 (en) * 1988-04-27 1988-06-02 Ici Plc Anti-tumour agents
EP0365763A1 (en) * 1988-09-30 1990-05-02 Agouron Pharmaceuticals, Inc. Antiproliferative cyclic compounds
US5286726A (en) * 1990-04-12 1994-02-15 The Regents Of The University Of Michigan Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
GB9013615D0 (en) 1990-06-19 1990-08-08 Wellcome Found Pharmaceutical compounds
US6762188B1 (en) 1990-06-19 2004-07-13 Smithkline Beecham Corporation Pharmaceutically active benzoquinazoline compounds
GB9105771D0 (en) * 1991-03-19 1991-05-01 Cancer Res Inst Royal Anti-cancer compounds
GB9205320D0 (en) * 1992-03-11 1992-04-22 Ici Plc Anti-tumour compounds
GB9205907D0 (en) * 1992-03-18 1992-04-29 Cancer Res Inst Royal Anti-cancer compounds
US5430148A (en) * 1992-03-31 1995-07-04 Agouron Pharmaceuticals, Inc. Antiproliferative quinazolines
GB9223352D0 (en) * 1992-11-06 1992-12-23 Ici Plc Tricyclic compounds
US7262058B2 (en) * 2001-03-09 2007-08-28 Nonda Katopodis Method for determining lipid associated sialoprotein in body fluids
KR20050061545A (ko) * 2002-10-18 2005-06-22 코닌클리케 필립스 일렉트로닉스 엔.브이. Tv-애니타임의 메타데이터 보호를 위한 방법 및 시스템
CA2502302A1 (en) * 2002-11-04 2004-05-21 Nps Pharmaceuticals, Inc. Quinazolinone compounds as calcilytics
WO2007011618A1 (en) * 2005-07-15 2007-01-25 Schering Corporation Quinazoline derivatives useful in cancer treatment
CA2615380A1 (en) * 2005-07-15 2007-01-25 Schering Corporation Quinazoline derivatives useful in cancer treatment
CN101547922B (zh) 2006-10-04 2012-06-20 辉瑞产品公司 作为钙受体拮抗剂的吡啶并[4,3-d]嘧啶-4(3H)-酮衍生物
CA2966280A1 (en) 2007-10-26 2009-04-30 The Regents Of The University Of California Diarylhydantoin compounds
HRP20171415T4 (hr) 2009-06-25 2023-03-03 Alkermes Pharma Ireland Limited Heterociklični spojevi za liječenje neuroloških i psiholoških poremećaja
JP6076740B2 (ja) * 2010-01-07 2017-02-08 アルカーメス ファーマ アイルランド リミテッド 第四級アンモニウム塩プロドラッグ
EP2585066B1 (en) 2010-06-24 2018-09-26 Alkermes Pharma Ireland Limited Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
US9034867B2 (en) 2011-03-18 2015-05-19 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising sorbitan esters
CA2867137C (en) 2012-03-19 2020-12-08 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising aripiprazole prodrugs and benzyl alcohol
JP6219918B2 (ja) 2012-03-19 2017-10-25 アルカームス ファーマ アイルランド リミテッド グリセロールエステルを含む医薬組成物
JP6471089B2 (ja) 2012-03-19 2019-02-13 アルカームス ファーマ アイルランド リミテッド 脂肪酸エステルを含む医薬組成物
ES2792149T3 (es) 2012-09-19 2020-11-10 Alkermes Pharma Ireland Ltd Composiciones farmacéuticas que tienen estabilidad de almacenamiento mejorada
MX2016012041A (es) 2014-03-20 2017-01-19 Alkermes Pharma Ireland Ltd Formulaciones de aripiprazol que tienen mayores velocidades de inyeccion.
JP7384812B2 (ja) 2018-03-05 2023-11-21 アルカームス ファーマ アイルランド リミテッド アリピプラゾール投与戦略
WO2024028999A1 (ja) * 2022-08-03 2024-02-08 Ils株式会社 N-[4-メチルアミノベンゾイル]-l-グルタミン酸ジエチルエステルの製造方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1021196A (en) * 1964-02-20 1966-03-02 Parke Davis & Co Novel amino acids and means for producing the same
US3471498A (en) * 1967-08-11 1969-10-07 Parke Davis & Co Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids
EP0031237B1 (en) 1979-12-19 1984-10-17 National Research Development Corporation Quinazoline derivatives, processes for their preparation, compositions containing them and their use as anti-cancer agents
GB8607683D0 (en) * 1986-03-27 1986-04-30 Ici Plc Anti-tumor agents

Also Published As

Publication number Publication date
DK255786D0 (da) 1986-05-30
EP0204529A2 (en) 1986-12-10
DE3688150T2 (de) 1993-07-29
EP0204529B1 (en) 1993-03-31
GB2175903B (en) 1988-10-12
ES555548A0 (es) 1987-12-01
PT82682B (pt) 1988-03-03
ATE87621T1 (de) 1993-04-15
IL78910A0 (en) 1986-09-30
GB8513754D0 (en) 1985-07-03
DK255786A (da) 1986-12-01
JPS61282368A (ja) 1986-12-12
NO862170L (no) 1986-12-01
NZ216363A (en) 1989-07-27
DE3688150D1 (de) 1993-05-06
ZA864051B (en) 1987-01-28
FI862303A0 (fi) 1986-05-30
ES8800911A1 (es) 1987-12-01
HUT45512A (en) 1988-07-28
GR861418B (en) 1986-09-26
AU5822086A (en) 1986-12-04
EP0204529A3 (en) 1987-11-19
US5236927A (en) 1993-08-17
PT82682A (en) 1986-06-01
GB8613184D0 (en) 1986-07-02
GB2175903A (en) 1986-12-10
AU592271B2 (en) 1990-01-04

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