DE3688150D1 - Antikrebs-chinazolinon-derivate. - Google Patents
Antikrebs-chinazolinon-derivate.Info
- Publication number
- DE3688150D1 DE3688150D1 DE8686304148T DE3688150T DE3688150D1 DE 3688150 D1 DE3688150 D1 DE 3688150D1 DE 8686304148 T DE8686304148 T DE 8686304148T DE 3688150 T DE3688150 T DE 3688150T DE 3688150 D1 DE3688150 D1 DE 3688150D1
- Authority
- DE
- Germany
- Prior art keywords
- group
- heteroatom
- cancer
- halogeno
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858513754A GB8513754D0 (en) | 1985-05-31 | 1985-05-31 | Anti-cancer quinazoline derivatives |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3688150D1 true DE3688150D1 (de) | 1993-05-06 |
DE3688150T2 DE3688150T2 (de) | 1993-07-29 |
Family
ID=10579966
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE8686304148T Expired - Fee Related DE3688150T2 (de) | 1985-05-31 | 1986-05-30 | Antikrebs-chinazolinon-derivate. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5236927A (de) |
EP (1) | EP0204529B1 (de) |
JP (1) | JPS61282368A (de) |
AT (1) | ATE87621T1 (de) |
AU (1) | AU592271B2 (de) |
DE (1) | DE3688150T2 (de) |
DK (1) | DK255786A (de) |
ES (1) | ES8800911A1 (de) |
FI (1) | FI862303A (de) |
GB (2) | GB8513754D0 (de) |
GR (1) | GR861418B (de) |
HU (1) | HUT45512A (de) |
IL (1) | IL78910A0 (de) |
NO (1) | NO862170L (de) |
NZ (1) | NZ216363A (de) |
PT (1) | PT82682B (de) |
ZA (1) | ZA864051B (de) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
GB8707053D0 (en) * | 1987-03-25 | 1987-04-29 | Ici Plc | Anti-tumour agents |
US4857530A (en) * | 1987-11-03 | 1989-08-15 | Warner-Lambert Company | Substituted quinazolinones as anticancer agents |
GB8809978D0 (en) * | 1988-04-27 | 1988-06-02 | Ici Plc | Anti-tumour agents |
EP0365763A1 (de) * | 1988-09-30 | 1990-05-02 | Agouron Pharmaceuticals, Inc. | Zyklische Verbindungen als Antiproleferahne |
US5286726A (en) * | 1990-04-12 | 1994-02-15 | The Regents Of The University Of Michigan | Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases |
US6762188B1 (en) | 1990-06-19 | 2004-07-13 | Smithkline Beecham Corporation | Pharmaceutically active benzoquinazoline compounds |
GB9013615D0 (en) * | 1990-06-19 | 1990-08-08 | Wellcome Found | Pharmaceutical compounds |
GB9105771D0 (en) * | 1991-03-19 | 1991-05-01 | Cancer Res Inst Royal | Anti-cancer compounds |
GB9205320D0 (en) * | 1992-03-11 | 1992-04-22 | Ici Plc | Anti-tumour compounds |
GB9205907D0 (en) * | 1992-03-18 | 1992-04-29 | Cancer Res Inst Royal | Anti-cancer compounds |
US5430148A (en) * | 1992-03-31 | 1995-07-04 | Agouron Pharmaceuticals, Inc. | Antiproliferative quinazolines |
GB9223352D0 (en) * | 1992-11-06 | 1992-12-23 | Ici Plc | Tricyclic compounds |
US7262058B2 (en) * | 2001-03-09 | 2007-08-28 | Nonda Katopodis | Method for determining lipid associated sialoprotein in body fluids |
BR0315403A (pt) * | 2002-10-18 | 2005-08-16 | Koninkl Philips Electronics Nv | Método, sistema, e dispositivo de assinatura para prover autenticação de integridade de dados e proteção de dados, dispositivo de verificação para verificar autenticação de integridade de dados e proteção de dados, sinal compreendendo fragmentos de dados, e, produto de programa de computador |
WO2004041755A2 (en) * | 2002-11-04 | 2004-05-21 | Nps Pharmaceuticals, Inc. | Quinazolinone compounds as calcilytics |
EP1924568A1 (de) * | 2005-07-15 | 2008-05-28 | Schering Corporation | Für die krebsbehandlung geeignete chinazolinderivate |
US20070015774A1 (en) * | 2005-07-15 | 2007-01-18 | Schering Corporation | Quinazoline derivatives useful in cancer treatment |
KR101129868B1 (ko) | 2006-10-04 | 2012-04-12 | 화이자 프로덕츠 인코포레이티드 | 칼슘 수용체 길항제로서의 피리도[4,3-d]피리미딘-4(3H)-온 유도체 |
EP2220050A2 (de) | 2007-10-26 | 2010-08-25 | The Regents Of The University Of California | Diarylhydantoinverbindungen als androgenrezeptormodulatoren |
US8431576B2 (en) | 2009-06-25 | 2013-04-30 | Alkermes Pharma Ireland Limited | Heterocyclic compounds for the treatment of neurological and psychological disorders |
WO2011084846A1 (en) * | 2010-01-07 | 2011-07-14 | Alkermes, Inc. | Quaternary ammonium salt prodrugs |
US8592427B2 (en) | 2010-06-24 | 2013-11-26 | Alkermes Pharma Ireland Limited | Prodrugs of NH-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
IL296695A (en) | 2011-03-18 | 2022-11-01 | Alkermes Pharma Ireland Ltd | Pharmaceutical preparations containing sorbitan esters |
JP6333802B2 (ja) | 2012-03-19 | 2018-05-30 | アルカームス ファーマ アイルランド リミテッド | ベンジルアルコールを含む医薬組成物 |
WO2013142198A1 (en) | 2012-03-19 | 2013-09-26 | Alkermes Pharma Ireland Limited | Pharmaaceutical compositions comprising fatty acid esters |
CA2867123C (en) | 2012-03-19 | 2021-02-16 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising water-insoluble antipsychotic agents and glycerol esters |
NZ730571A (en) | 2012-09-19 | 2018-12-21 | Alkermes Pharma Ireland Ltd | Pharmaceutical compositions having improved storage stability |
EP3119399A4 (de) | 2014-03-20 | 2017-09-27 | Alkermes Pharma Ireland Limited | Aripiprazolformulierungen mit erhöhten injektionsgeschwindigkeiten |
US11273158B2 (en) | 2018-03-05 | 2022-03-15 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
WO2024028999A1 (ja) * | 2022-08-03 | 2024-02-08 | Ils株式会社 | N-[4-メチルアミノベンゾイル]-l-グルタミン酸ジエチルエステルの製造方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1021196A (en) * | 1964-02-20 | 1966-03-02 | Parke Davis & Co | Novel amino acids and means for producing the same |
US3471498A (en) * | 1967-08-11 | 1969-10-07 | Parke Davis & Co | Certain n-p-((2,4-diamino-6-quinazolinyl)-methyl)benzoylamino acids |
GB2065653B (en) * | 1979-12-19 | 1983-03-09 | Nat Res Dev | Anti-cancer quinazoline derivatives |
GB8607683D0 (en) * | 1986-03-27 | 1986-04-30 | Ici Plc | Anti-tumor agents |
-
1985
- 1985-05-31 GB GB858513754A patent/GB8513754D0/en active Pending
-
1986
- 1986-05-26 IL IL78910A patent/IL78910A0/xx unknown
- 1986-05-30 AT AT86304148T patent/ATE87621T1/de not_active IP Right Cessation
- 1986-05-30 NO NO862170A patent/NO862170L/no unknown
- 1986-05-30 NZ NZ216363A patent/NZ216363A/xx unknown
- 1986-05-30 DK DK255786A patent/DK255786A/da not_active Application Discontinuation
- 1986-05-30 GR GR861418A patent/GR861418B/el unknown
- 1986-05-30 DE DE8686304148T patent/DE3688150T2/de not_active Expired - Fee Related
- 1986-05-30 HU HU862288A patent/HUT45512A/hu unknown
- 1986-05-30 JP JP61125587A patent/JPS61282368A/ja active Pending
- 1986-05-30 AU AU58220/86A patent/AU592271B2/en not_active Ceased
- 1986-05-30 FI FI862303A patent/FI862303A/fi not_active Application Discontinuation
- 1986-05-30 GB GB08613184A patent/GB2175903B/en not_active Expired
- 1986-05-30 ES ES555548A patent/ES8800911A1/es not_active Expired
- 1986-05-30 EP EP86304148A patent/EP0204529B1/de not_active Expired - Lifetime
- 1986-05-30 PT PT82682A patent/PT82682B/pt not_active IP Right Cessation
- 1986-05-30 ZA ZA864051A patent/ZA864051B/xx unknown
-
1990
- 1990-12-12 US US07/625,695 patent/US5236927A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
GB2175903A (en) | 1986-12-10 |
DK255786D0 (da) | 1986-05-30 |
US5236927A (en) | 1993-08-17 |
ZA864051B (en) | 1987-01-28 |
HUT45512A (en) | 1988-07-28 |
ES8800911A1 (es) | 1987-12-01 |
NO862170L (no) | 1986-12-01 |
FI862303A0 (fi) | 1986-05-30 |
AU592271B2 (en) | 1990-01-04 |
FI862303A (fi) | 1986-12-01 |
PT82682B (pt) | 1988-03-03 |
DE3688150T2 (de) | 1993-07-29 |
GR861418B (en) | 1986-09-26 |
ATE87621T1 (de) | 1993-04-15 |
EP0204529B1 (de) | 1993-03-31 |
GB8513754D0 (en) | 1985-07-03 |
JPS61282368A (ja) | 1986-12-12 |
ES555548A0 (es) | 1987-12-01 |
DK255786A (da) | 1986-12-01 |
AU5822086A (en) | 1986-12-04 |
GB2175903B (en) | 1988-10-12 |
EP0204529A2 (de) | 1986-12-10 |
IL78910A0 (en) | 1986-09-30 |
EP0204529A3 (en) | 1987-11-19 |
PT82682A (en) | 1986-06-01 |
GB8613184D0 (en) | 1986-07-02 |
NZ216363A (en) | 1989-07-27 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |