IL78773A - 2-(4-benzoyl-1-piperidyl)-1-phenylalkanol derivatives,process for their preparation and pharmaceutical compositions comprising them - Google Patents

2-(4-benzoyl-1-piperidyl)-1-phenylalkanol derivatives,process for their preparation and pharmaceutical compositions comprising them

Info

Publication number
IL78773A
IL78773A IL78773A IL7877386A IL78773A IL 78773 A IL78773 A IL 78773A IL 78773 A IL78773 A IL 78773A IL 7877386 A IL7877386 A IL 7877386A IL 78773 A IL78773 A IL 78773A
Authority
IL
Israel
Prior art keywords
piperidyl
benzoyl
preparation
pharmaceutical compositions
methoxy
Prior art date
Application number
IL78773A
Other languages
English (en)
Other versions
IL78773A0 (en
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of IL78773A0 publication Critical patent/IL78773A0/xx
Publication of IL78773A publication Critical patent/IL78773A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Organic Insulating Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Steroid Compounds (AREA)
IL78773A 1985-05-14 1986-05-13 2-(4-benzoyl-1-piperidyl)-1-phenylalkanol derivatives,process for their preparation and pharmaceutical compositions comprising them IL78773A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8507270A FR2581993B1 (fr) 1985-05-14 1985-05-14 Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
IL78773A0 IL78773A0 (en) 1986-08-31
IL78773A true IL78773A (en) 1990-09-17

Family

ID=9319247

Family Applications (1)

Application Number Title Priority Date Filing Date
IL78773A IL78773A (en) 1985-05-14 1986-05-13 2-(4-benzoyl-1-piperidyl)-1-phenylalkanol derivatives,process for their preparation and pharmaceutical compositions comprising them

Country Status (18)

Country Link
US (1) US4711899A (xx)
EP (1) EP0202164B1 (xx)
JP (1) JPS61260063A (xx)
KR (1) KR860008976A (xx)
AT (1) ATE40684T1 (xx)
AU (1) AU584701B2 (xx)
DE (1) DE3662044D1 (xx)
DK (1) DK220386A (xx)
ES (2) ES8802138A1 (xx)
FI (1) FI861995A (xx)
FR (1) FR2581993B1 (xx)
GR (1) GR861253B (xx)
HU (1) HU195640B (xx)
IL (1) IL78773A (xx)
NO (1) NO861897L (xx)
NZ (1) NZ216145A (xx)
PT (1) PT82569B (xx)
ZA (1) ZA863533B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR910006138B1 (ko) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 환상아민 유도체
JP2573195B2 (ja) * 1986-09-30 1997-01-22 エーザイ株式会社 環状アミン誘導体
US4870083A (en) * 1987-11-24 1989-09-26 Merrell Dow Pharmaceuticals Inc. 1,4-Disubstituted-piperidinyl compounds useful as analgesics and muscle relaxants
US5166211A (en) * 1987-12-17 1992-11-24 Merrell Dow Pharmaceuticals Inc. Method of using 1,4-disubstituted piperidinyl compounds in the treatment of coronary vasospasons and variant angina
US5093341A (en) * 1987-12-17 1992-03-03 Merrell Dow Pharmaceuticals Inc. N-aralkyl piperidine derivatives useful as antithrombolytic agents
US5064838A (en) * 1988-01-21 1991-11-12 Merrell Dow Pharmaceuticals 1,4-disubstituted-piperidinyl compounds as pain relievers
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
FR2634206B1 (fr) * 1988-07-12 1992-05-15 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2 et quinoleinones-2, leur preparation et leur application en therapeutique
GB8823775D0 (en) * 1988-10-11 1988-11-16 Scras New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
US5055470A (en) * 1989-06-01 1991-10-08 Bristol-Myers Squibb Co. Method of treatment of ischemia in brain
US4994460A (en) * 1989-06-01 1991-02-19 Bristol-Myers Squibb Co. Agents for treatment of brain ischemia
NZ236501A (en) * 1989-12-21 1992-12-23 Merrell Dow Pharma Piperidine derivatives and antithrombotic compositions
US5292752A (en) * 1989-12-21 1994-03-08 Merrell Dow Pharmaceuticals Inc. Antithrombotic compounds
DE69132141T2 (de) * 1990-05-10 2000-09-21 Pfizer Inc., New York Neuroprotective indolone und verwandte derivate
US5478846A (en) * 1990-06-07 1995-12-26 Merrell Dow Pharmaceuticals Inc. 1-piperidinyl alkanoylanyl sulfonamides for treatment of cardiac arrhythmia
DE69123052T2 (de) * 1990-06-07 1997-03-06 Merrell Pharmaceuticals Inc., Cincinnati, Ohio Derivate des 1-piperidinyl-alkanoylarylsulfonamids
US5512584A (en) * 1991-04-16 1996-04-30 Basf Aktiengesellschaft 1,3,4-trisubstituted piperidine derivatives, the preparation and use thereof
FR2678269B1 (fr) * 1991-06-27 1995-01-13 Synthelabo Derives de 1-(4-chlorophenyl)-2-[4-(2-phenylethyl)piperidin-1-yl]ethanol, leur application et leur preparation en therapeutique.
FR2688504B1 (fr) * 1992-03-13 1995-05-05 Synthelabo Derives de 2-(piperidin-1-yl)ethanol, leur preparation et leur application en therapeutique.
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
AU684568B2 (en) * 1994-01-31 1997-12-18 Pfizer Inc. Neuroprotective chroman compounds
FR2737494B1 (fr) * 1995-08-04 1997-08-29 Synthelabo Derives de benzenesulfonamide, leur preparation et leur application en therapeutique
US6770659B2 (en) * 2002-08-26 2004-08-03 Sk Corporation Benzoyl piperidine compounds
US20050158270A1 (en) * 2004-01-15 2005-07-21 Seren Frantz Pearlizer concentrate and its use in personal care compositions

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH492708A (de) * 1968-01-11 1970-06-30 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3632767A (en) * 1968-02-12 1972-01-04 Mallinckrodt Chemical Works Treatment of depression with 4-substituted piperidines
US3576810A (en) * 1968-06-20 1971-04-27 Robins Co Inc A H 1-substituted-3-(-4)-aroylpiperidines
BE791088A (fr) * 1971-11-09 1973-03-01 Richardson Merrell Inc Nouveaux derives d'aryl (piperidyl-4) cetone, utiles notamment comme analgesiques et anticoagulants, et leur procede de preparation
US4101662A (en) * 1973-05-03 1978-07-18 A. H. Robins Company, Incorporated Method for inhibiting emesis and compositions therefor
GB1535791A (en) * 1975-05-07 1978-12-13 Ferrosan Ab Derivatives of 4-piperidinol
US4035369A (en) * 1975-10-08 1977-07-12 Janssen Pharmaceutica N.V. 1-Benzazolylalkyl-4-substituted-piperidines
CH602642A5 (xx) * 1975-11-14 1978-07-31 Orgamol Sa
FR2408602A2 (fr) * 1977-11-15 1979-06-08 Synthelabo Nouveaux derives de piperidine et leur methode de preparation
US4335127A (en) * 1979-01-08 1982-06-15 Janssen Pharmaceutica, N.V. Piperidinylalkyl quinazoline compounds, composition and method of use
US4198419A (en) * 1979-01-10 1980-04-15 American Hoechst Corporation Phenylthiophenylpiperidines
US4443451A (en) * 1981-07-15 1984-04-17 Janssen Pharmaceutica N.V. Bicyclic pyrimidin-5-one derivatives
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
DK159420C (da) * 1983-03-09 1991-03-11 Ciba Geigy Ag N-(piperidinyl-alkyl)-carboxamider og salte deraf, farmaceutiske praeparater indeholdende disse forbindelser samt anvendelsen af forbindelserne til fremstilling af antipsykotiske farmaceutiske praeparater
US4458076A (en) * 1983-05-31 1984-07-03 Hoechst-Roussel Pharmaceuticals 3-(4-Piperidinyl)-1,2-benzisothiazoles

Also Published As

Publication number Publication date
EP0202164A1 (fr) 1986-11-20
ES557582A0 (es) 1988-02-16
PT82569A (fr) 1986-06-01
ATE40684T1 (de) 1989-02-15
HU195640B (en) 1988-06-28
FI861995A0 (fi) 1986-05-13
JPS61260063A (ja) 1986-11-18
AU5740686A (en) 1986-11-20
ES8802138A1 (es) 1988-04-01
AU584701B2 (en) 1989-06-01
ES8801631A1 (es) 1988-02-16
GR861253B (en) 1986-09-10
FI861995A (fi) 1986-11-15
HUT40790A (en) 1987-02-27
PT82569B (fr) 1988-04-12
KR860008976A (ko) 1986-12-19
ZA863533B (en) 1986-12-30
DK220386D0 (da) 1986-05-13
FR2581993B1 (fr) 1988-03-18
NO861897L (no) 1986-11-17
EP0202164B1 (fr) 1989-02-08
DK220386A (da) 1986-11-15
NZ216145A (en) 1988-10-28
DE3662044D1 (en) 1989-03-16
ES554895A0 (es) 1988-04-01
FR2581993A1 (fr) 1986-11-21
IL78773A0 (en) 1986-08-31
US4711899A (en) 1987-12-08

Similar Documents

Publication Publication Date Title
IL78773A (en) 2-(4-benzoyl-1-piperidyl)-1-phenylalkanol derivatives,process for their preparation and pharmaceutical compositions comprising them
AU2058283A (en) 2-amino-3-acylamino-6-benzylamino pyridine derivatives
SE8802412D0 (sv) Thiourea derivatives
ES8802489A1 (es) Procedimiento para la obtencion de benzamidas
ES8801637A1 (es) Un procedimiento para la preparacion de benzimidazoles.
PT84161B (pt) Processo para a preparacao de derivados de 3-acilaminometil-imidazo-{1,2-a}-piridinas e de composicoes farmaceuticas que os contem
NO872874D0 (no) Amid-derivater.
DE3566666D1 (en) Substituted pyridazinones, method for their preparation, pharmaceutical preparation containing these compounds and their use
ES8506310A1 (es) N-oxidos de derivados aminociclicos
DE3469527D1 (en) Nortropine derivative, process for its preparation and its use
ES8603818A1 (es) Un metodo para preparar un derivado de acido benzoilpropio- nico
FI882421A (fi) 5-fenyl-1,2,3a,4,5,9b-hexahydro-3h -benz(e)indol, deras framstaellning och anvaendning som laekemedel.