IL77430A - 3-alkyl-and 3,8-dialkyl-6-thioxanthine and pharmaceutical compositions containing them - Google Patents

3-alkyl-and 3,8-dialkyl-6-thioxanthine and pharmaceutical compositions containing them

Info

Publication number
IL77430A
IL77430A IL77430A IL7743085A IL77430A IL 77430 A IL77430 A IL 77430A IL 77430 A IL77430 A IL 77430A IL 7743085 A IL7743085 A IL 7743085A IL 77430 A IL77430 A IL 77430A
Authority
IL
Israel
Prior art keywords
thioxanthine
dialkyl
alkyl
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL77430A
Other languages
English (en)
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of IL77430A publication Critical patent/IL77430A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL77430A 1985-02-07 1985-12-24 3-alkyl-and 3,8-dialkyl-6-thioxanthine and pharmaceutical compositions containing them IL77430A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/699,254 US4710503A (en) 1985-02-07 1985-02-07 6-thioxanthine derivatives

Publications (1)

Publication Number Publication Date
IL77430A true IL77430A (en) 1988-10-31

Family

ID=24808534

Family Applications (1)

Application Number Title Priority Date Filing Date
IL77430A IL77430A (en) 1985-02-07 1985-12-24 3-alkyl-and 3,8-dialkyl-6-thioxanthine and pharmaceutical compositions containing them

Country Status (16)

Country Link
US (2) US4710503A (no)
EP (1) EP0191313B1 (no)
JP (2) JPH0780882B2 (no)
KR (1) KR930002492B1 (no)
CN (1) CN1013676B (no)
AT (1) ATE81858T1 (no)
AU (1) AU570142B2 (no)
CA (1) CA1275288C (no)
DE (1) DE3687007T2 (no)
DK (1) DK161964C (no)
FI (1) FI84180C (no)
IL (1) IL77430A (no)
IN (1) IN161914B (no)
NO (1) NO163569C (no)
NZ (1) NZ214653A (no)
ZA (1) ZA859805B (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines
US5310916A (en) * 1988-07-19 1994-05-10 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Trifunctional agents useful as irreversible inhibitors of A1-adenosine receptors
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
AU5436790A (en) * 1989-04-19 1990-11-16 United States of America, as represented by the Secretary, U.S. Department of Commerce, The Sulfer-containing xanthine derivatives as adenosin antagonists
CA2028235C (en) 1989-10-20 1997-01-21 Fumio Suzuki Condensed purine derivatives
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
EP0799040B1 (en) * 1994-12-13 2003-08-20 Euroceltique S.A. Trisubstituted thioxanthines
ATE247116T1 (de) * 1994-12-13 2003-08-15 Euro Celtique Sa Arylthioxanthine
WO1996018400A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Trisubstituted thioxanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
AR039385A1 (es) * 2002-04-19 2005-02-16 Astrazeneca Ab Derivados de tioxantina como inhibidores de la mieloperoxidasa
SE0302756D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel Compounds
SE0402591D0 (sv) * 2004-10-25 2004-10-25 Astrazeneca Ab Novel use
MY140748A (en) 2004-12-06 2010-01-15 Astrazeneca Ab Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
TW200804383A (en) 2006-06-05 2008-01-16 Astrazeneca Ab New compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE587119A (fr) * 1959-10-22 1960-07-29 May & Baker Ltd Nouveaux dérivés de la thioxanthine, leur préparation et les compositions pharmaceutiques qui les contiennent.
SE8002910L (sv) * 1980-04-18 1981-10-19 Draco Ab 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8510758D0 (en) * 1985-04-27 1985-06-05 Wellcome Found Compounds
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines

Also Published As

Publication number Publication date
JPS61183287A (ja) 1986-08-15
FI860285A0 (fi) 1986-01-21
KR930002492B1 (ko) 1993-04-02
DE3687007T2 (de) 1993-06-03
ATE81858T1 (de) 1992-11-15
AU570142B2 (en) 1988-03-03
EP0191313B1 (en) 1992-10-28
JP2888273B2 (ja) 1999-05-10
CN86101050A (zh) 1986-11-12
AU5184086A (en) 1986-08-14
DK161964B (da) 1991-09-02
NZ214653A (en) 1988-07-28
NO163569C (no) 1990-06-20
NO860424L (no) 1986-08-08
JPH0780882B2 (ja) 1995-08-30
KR860006464A (ko) 1986-09-11
DE3687007D1 (en) 1992-12-03
NO163569B (no) 1990-03-12
FI84180B (fi) 1991-07-15
DK161964C (da) 1992-02-10
DK33286A (da) 1986-08-08
ZA859805B (en) 1986-08-27
IN161914B (no) 1988-02-27
FI860285A (fi) 1986-08-08
US4710503A (en) 1987-12-01
EP0191313A1 (en) 1986-08-20
JPH0899882A (ja) 1996-04-16
DK33286D0 (da) 1986-01-22
CA1275288C (en) 1990-10-16
FI84180C (fi) 1991-10-25
US4820709A (en) 1989-04-11
CN1013676B (zh) 1991-08-28

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