FI860285A - 6-tioxantinderivat. - Google Patents

6-tioxantinderivat. Download PDF

Info

Publication number
FI860285A
FI860285A FI860285A FI860285A FI860285A FI 860285 A FI860285 A FI 860285A FI 860285 A FI860285 A FI 860285A FI 860285 A FI860285 A FI 860285A FI 860285 A FI860285 A FI 860285A
Authority
FI
Finland
Prior art keywords
ethyl
compounds
activity
tioxantinderivat
reduced
Prior art date
Application number
FI860285A
Other languages
English (en)
Other versions
FI84180B (fi
FI84180C (fi
FI860285A0 (fi
Inventor
Peter Hofer
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of FI860285A0 publication Critical patent/FI860285A0/fi
Publication of FI860285A publication Critical patent/FI860285A/fi
Publication of FI84180B publication Critical patent/FI84180B/fi
Application granted granted Critical
Publication of FI84180C publication Critical patent/FI84180C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/22—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one sulfur atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Catalysts (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI860285A 1985-02-07 1986-01-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara 6-tioxantinderivat. FI84180C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US69925485 1985-02-07
US06/699,254 US4710503A (en) 1985-02-07 1985-02-07 6-thioxanthine derivatives

Publications (4)

Publication Number Publication Date
FI860285A0 FI860285A0 (fi) 1986-01-21
FI860285A true FI860285A (fi) 1986-08-08
FI84180B FI84180B (fi) 1991-07-15
FI84180C FI84180C (fi) 1991-10-25

Family

ID=24808534

Family Applications (1)

Application Number Title Priority Date Filing Date
FI860285A FI84180C (fi) 1985-02-07 1986-01-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara 6-tioxantinderivat.

Country Status (16)

Country Link
US (2) US4710503A (fi)
EP (1) EP0191313B1 (fi)
JP (2) JPH0780882B2 (fi)
KR (1) KR930002492B1 (fi)
CN (1) CN1013676B (fi)
AT (1) ATE81858T1 (fi)
AU (1) AU570142B2 (fi)
CA (1) CA1275288C (fi)
DE (1) DE3687007T2 (fi)
DK (1) DK161964C (fi)
FI (1) FI84180C (fi)
IL (1) IL77430A (fi)
IN (1) IN161914B (fi)
NO (1) NO163569C (fi)
NZ (1) NZ214653A (fi)
ZA (1) ZA859805B (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines
US5298508A (en) * 1988-07-19 1994-03-29 The United States Of America As Represented By The Department Of Health And Human Services Irreversible inhibitors of adenosine receptors
US5310916A (en) * 1988-07-19 1994-05-10 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Trifunctional agents useful as irreversible inhibitors of A1-adenosine receptors
WO1990012797A1 (en) * 1989-04-19 1990-11-01 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Sulfer-containing xanthine derivatives as adenosin antagonists
ATE195739T1 (de) 1989-10-20 2000-09-15 Kyowa Hakko Kogyo Kk Kondensierte purinderivate
GB9312853D0 (en) * 1993-06-22 1993-08-04 Euro Celtique Sa Chemical compounds
US5922751A (en) * 1994-06-24 1999-07-13 Euro-Celtique, S.A. Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
US5591776A (en) * 1994-06-24 1997-01-07 Euro-Celtique, S.A. Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
AU4527996A (en) * 1994-12-13 1996-07-03 Euro-Celtique S.A. Trisubstituted thioxanthines
US6025361A (en) * 1994-12-13 2000-02-15 Euro-Celtique, S.A. Trisubstituted thioxanthines
WO1996018400A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Trisubstituted thioxanthines
WO1996018399A1 (en) * 1994-12-13 1996-06-20 Euro-Celtique, S.A. Aryl thioxanthines
US6166041A (en) * 1995-10-11 2000-12-26 Euro-Celtique, S.A. 2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
US6316423B1 (en) 1996-04-10 2001-11-13 The United States Of America As Represented By The Departmant Of Health And Human Services Method of treating ischemic, hypoxic and anoxic brain damage
US6075016A (en) * 1996-04-10 2000-06-13 Euro-Celtique S.A. 6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US5864037A (en) 1996-06-06 1999-01-26 Euro-Celtique, S.A. Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
US5744473A (en) * 1996-09-16 1998-04-28 Euro-Celtique, S.A. PDE IV inhibitors: "bis-compounds"
AR039385A1 (es) * 2002-04-19 2005-02-16 Astrazeneca Ab Derivados de tioxantina como inhibidores de la mieloperoxidasa
SE0302756D0 (sv) * 2003-10-17 2003-10-17 Astrazeneca Ab Novel Compounds
SE0402591D0 (sv) * 2004-10-25 2004-10-25 Astrazeneca Ab Novel use
MY140748A (en) * 2004-12-06 2010-01-15 Astrazeneca Ab Novel pyrrolo [3,2-d] pyrimidin-4-one derivatives and their use in therapy
TW200804383A (en) 2006-06-05 2008-01-16 Astrazeneca Ab New compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE587119A (fr) * 1959-10-22 1960-07-29 May & Baker Ltd Nouveaux dérivés de la thioxanthine, leur préparation et les compositions pharmaceutiques qui les contiennent.
SE8002910L (sv) * 1980-04-18 1981-10-19 Draco Ab 3,8-dialkylxantiner, forfarande for deras framstellning, beredning och metoder for behandling av kronisk obstruktiv luftvegssjukdom och kardiovaskulera sjukdomar
US4710503A (en) * 1985-02-07 1987-12-01 Euroceltique S.A. 6-thioxanthine derivatives
GB8510758D0 (en) * 1985-04-27 1985-06-05 Wellcome Found Compounds
GB8618931D0 (en) * 1986-08-02 1986-09-10 Euro Celtique Sa 6-thioxanthines

Also Published As

Publication number Publication date
JP2888273B2 (ja) 1999-05-10
CN1013676B (zh) 1991-08-28
NZ214653A (en) 1988-07-28
FI84180B (fi) 1991-07-15
JPH0780882B2 (ja) 1995-08-30
FI84180C (fi) 1991-10-25
DK161964B (da) 1991-09-02
IL77430A (en) 1988-10-31
EP0191313B1 (en) 1992-10-28
DK33286A (da) 1986-08-08
IN161914B (fi) 1988-02-27
US4820709A (en) 1989-04-11
NO163569C (no) 1990-06-20
DK33286D0 (da) 1986-01-22
CN86101050A (zh) 1986-11-12
JPS61183287A (ja) 1986-08-15
FI860285A0 (fi) 1986-01-21
CA1275288C (en) 1990-10-16
KR930002492B1 (ko) 1993-04-02
NO860424L (no) 1986-08-08
EP0191313A1 (en) 1986-08-20
ZA859805B (en) 1986-08-27
KR860006464A (ko) 1986-09-11
DK161964C (da) 1992-02-10
DE3687007D1 (en) 1992-12-03
US4710503A (en) 1987-12-01
NO163569B (no) 1990-03-12
DE3687007T2 (de) 1993-06-03
AU5184086A (en) 1986-08-14
JPH0899882A (ja) 1996-04-16
ATE81858T1 (de) 1992-11-15
AU570142B2 (en) 1988-03-03

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Legal Events

Date Code Title Description
FG Patent granted

Owner name: EUROCELTIQUE, S.A.

MA Patent expired