IL76699A - Recombinant human tumor necrosis factor, its production and pharmaceutical compositions containing it - Google Patents

Recombinant human tumor necrosis factor, its production and pharmaceutical compositions containing it

Info

Publication number
IL76699A
IL76699A IL76699A IL7669985A IL76699A IL 76699 A IL76699 A IL 76699A IL 76699 A IL76699 A IL 76699A IL 7669985 A IL7669985 A IL 7669985A IL 76699 A IL76699 A IL 76699A
Authority
IL
Israel
Prior art keywords
tnf
dna
sequence
cells
protein
Prior art date
Application number
IL76699A
Other languages
English (en)
Other versions
IL76699A0 (en
Original Assignee
Cetus Oncology Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/730,696 external-priority patent/US4677064A/en
Priority claimed from US06/760,661 external-priority patent/US4677063A/en
Application filed by Cetus Oncology Corp filed Critical Cetus Oncology Corp
Publication of IL76699A0 publication Critical patent/IL76699A0/xx
Publication of IL76699A publication Critical patent/IL76699A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
IL76699A 1984-10-15 1985-10-14 Recombinant human tumor necrosis factor, its production and pharmaceutical compositions containing it IL76699A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US66102684A 1984-10-15 1984-10-15
US67036084A 1984-11-09 1984-11-09
US06/730,696 US4677064A (en) 1984-11-09 1985-05-02 Human tumor necrosis factor
US06/760,661 US4677063A (en) 1985-05-02 1985-07-30 Human tumor necrosis factor

Publications (2)

Publication Number Publication Date
IL76699A0 IL76699A0 (en) 1986-02-28
IL76699A true IL76699A (en) 1998-03-10

Family

ID=27505306

Family Applications (1)

Application Number Title Priority Date Filing Date
IL76699A IL76699A (en) 1984-10-15 1985-10-14 Recombinant human tumor necrosis factor, its production and pharmaceutical compositions containing it

Country Status (11)

Country Link
EP (1) EP0200748B1 (de)
JP (1) JPH0866194A (de)
AU (1) AU589919B2 (de)
BG (1) BG60238B1 (de)
DE (1) DE3581730D1 (de)
DK (1) DK279886D0 (de)
ES (1) ES8704547A1 (de)
FI (1) FI862531L (de)
IL (1) IL76699A (de)
NO (1) NO174970C (de)
WO (1) WO1986002381A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5288852A (en) * 1984-03-06 1994-02-22 Dainippon Pharmaceutical Co., Ltd. Human tumor necrosis factor polypeptides
DE3582183D1 (de) * 1984-03-06 1991-04-25 Dainippon Pharmaceutical Co Dns den menschlichen tumornekrosisfaktor kodierend und das menschliche tumornekronisfaktor-polypeptid.
JPS6248634A (ja) * 1985-07-23 1987-03-03 Mochida Pharmaceut Co Ltd 新規アミノ酸組成物、その製造方法及び該アミノ酸組成物を含有する医療組成物
CA1286843C (en) * 1985-10-30 1991-07-23 Leo S. Lin Purification method for proteins
US5425940A (en) * 1986-04-09 1995-06-20 Cetus Oncology Corporation Combination therapy using interleukin-2 and tumor necrosis factor
ATE107362T1 (de) * 1986-06-20 1994-07-15 Dainippon Pharmaceutical Co Polypeptid-mutanten des menschlichen tnf und für diese mutanten codierende dns.
FR2601678B1 (fr) * 1986-07-18 1989-11-24 Inst Nat Sante Rech Med Peptides comprenant la sequence seryl-aspartyl-lysyl-prolyle, procede pour l'extraction du tetrapeptide correspondant, et applications, notamment a la protection de la moelle osseuse au cours de traitements anticancereux par la chimiotherapie
WO1988006625A2 (en) * 1987-02-26 1988-09-07 Cetus Corporation Arginine-depleted human tumor necrosis factor
DE3837012A1 (de) * 1988-01-15 1989-07-27 Knoll Ag Verwendung von tnf und lt zur herstellung von arzneimitteln
JPH0797997B2 (ja) * 1988-04-28 1995-10-25 帝人株式会社 新規生理活性ポリペプチド
DE3841764A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3841768A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3841754A1 (de) * 1988-12-12 1990-06-13 Basf Ag Neue tnf-peptide
DE3843534A1 (de) * 1988-12-23 1990-07-12 Basf Ag Neue tnf-polypeptide
GB8905606D0 (en) * 1989-03-11 1989-04-26 Scras Peptides
ATE148992T1 (de) 1989-08-16 1997-03-15 Chiron Corp Zusammensetzungen zur hemmung der bildung von proteinhormon und deren verwendungen
WO1991006658A2 (en) * 1989-10-24 1991-05-16 Cetus Corporation Infective protein delivery system
HRP20211353T1 (hr) 2013-02-07 2021-11-26 The General Hospital Corporation Postupci za ekspanziju ili depleciju regulacijskih t-stanica

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL90047A (en) * 1982-10-19 1992-12-01 Cetus Oncology Corp Cysteine-depleted biologically active muteins other than interferon - '
US4518584A (en) 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
DE3472793D1 (en) * 1983-12-26 1988-08-25 Asahi Chemical Ind A novel physiologically active polypeptide
DE3582183D1 (de) * 1984-03-06 1991-04-25 Dainippon Pharmaceutical Co Dns den menschlichen tumornekrosisfaktor kodierend und das menschliche tumornekronisfaktor-polypeptid.
US4879226A (en) * 1984-04-06 1989-11-07 Asahi Kasei Kogyo Kabushiki Kaisha Novel human physiologically active polypeptide
DE3517153A1 (de) * 1985-01-07 1986-07-10 Murillo Contreras, Jesús, México Feuerhemmende beschichtungsmischung und verfahren zu deren herstellung
JP2515975B2 (ja) * 1985-02-26 1996-07-10 大日本製薬株式会社 抗腫瘍作用を有するポリペプチド

Also Published As

Publication number Publication date
NO174970C (no) 1994-08-10
DK279886A (da) 1986-06-13
ES547871A0 (es) 1987-04-01
EP0200748A1 (de) 1986-11-12
WO1986002381A1 (en) 1986-04-24
FI862531A0 (fi) 1986-06-13
NO862353D0 (no) 1986-06-12
AU589919B2 (en) 1989-10-26
FI862531A7 (fi) 1986-06-13
BG60238B1 (bg) 1994-01-24
AU5010685A (en) 1986-05-02
ES8704547A1 (es) 1987-04-01
BG60238B2 (bg) 1994-01-18
JPH0866194A (ja) 1996-03-12
EP0200748B1 (de) 1991-02-06
NO174970B (no) 1994-05-02
FI862531L (fi) 1986-06-13
IL76699A0 (en) 1986-02-28
DE3581730D1 (de) 1991-03-14
NO862353L (no) 1986-06-12
DK279886D0 (da) 1986-06-13

Similar Documents

Publication Publication Date Title
US4677063A (en) Human tumor necrosis factor
US4677064A (en) Human tumor necrosis factor
FI99015C (fi) Menetelmä biologisesti aktiivisen kasvaimen nekroositekijä-proteiinin muteiinin valmistamiseksi
JP2644794B2 (ja) 新規な型のコロニー刺激因子―１
AU589919B2 (en) Human tumor necrosis factor
CA1341240C (en) Dna encoding human tumor necrosis factor and human tumor necrosis factor polypeptide
US5288852A (en) Human tumor necrosis factor polypeptides
US4847201A (en) DNA encoding for CSF-1 and accompanying recombinant systems
FI100972B (fi) Pesäkkeitä stimuloivaa tekijä-1:tä (CSF-1) koodaava DNA-sekvenssi ja m enetelmä CSF-1-proteiinin valmistamiseksi
EP0256843A1 (de) Expression von G-CSF, Muteine davon und deren Verwendung
HU196457B (en) Process for producing interferons
HU202287B (en) Process for producing human immune interferon
IE58709B1 (en) Purification, production and use of tumor necrosis factors
US5672343A (en) N- 3 deletion mutants of the long form of CSF-1
JPS6361960B2 (de)
JP2675294B2 (ja) ヒト腫瘍壊死因子
NO863976L (no) Cystein-beroevede muteiner av biologisk aktive human tumornekrosefaktorproteiner.

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
FF Patent granted
KB Patent renewed
RH1 Patent not in force