IL75817A - Alicyclic,aromatic and heterocyclic amides substituted by quinolyl or naphthyridinyl ring systems,their preparation and pharmaceuticals containing them - Google Patents

Alicyclic,aromatic and heterocyclic amides substituted by quinolyl or naphthyridinyl ring systems,their preparation and pharmaceuticals containing them

Info

Publication number
IL75817A
IL75817A IL75817A IL7581785A IL75817A IL 75817 A IL75817 A IL 75817A IL 75817 A IL75817 A IL 75817A IL 7581785 A IL7581785 A IL 7581785A IL 75817 A IL75817 A IL 75817A
Authority
IL
Israel
Prior art keywords
radical
quinolyl
alkyloxy
alkyl
het
Prior art date
Application number
IL75817A
Other languages
English (en)
Other versions
IL75817A0 (en
Original Assignee
Rhone Poulenc Sante
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante filed Critical Rhone Poulenc Sante
Publication of IL75817A0 publication Critical patent/IL75817A0/xx
Priority to IL8781273A priority Critical patent/IL81273A/xx
Publication of IL75817A publication Critical patent/IL75817A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Cephalosporin Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL75817A 1984-07-19 1985-07-15 Alicyclic,aromatic and heterocyclic amides substituted by quinolyl or naphthyridinyl ring systems,their preparation and pharmaceuticals containing them IL75817A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
IL8781273A IL81273A (en) 1985-07-15 1987-01-15 Substituted amides,process for their preparation and pharmaceutical compositions containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8411442A FR2567887B1 (fr) 1984-07-19 1984-07-19 Nouveaux amides substitues, leur preparation et les medicaments qui les contiennent

Publications (2)

Publication Number Publication Date
IL75817A0 IL75817A0 (en) 1985-11-29
IL75817A true IL75817A (en) 1988-06-30

Family

ID=9306273

Family Applications (1)

Application Number Title Priority Date Filing Date
IL75817A IL75817A (en) 1984-07-19 1985-07-15 Alicyclic,aromatic and heterocyclic amides substituted by quinolyl or naphthyridinyl ring systems,their preparation and pharmaceuticals containing them

Country Status (27)

Country Link
US (1) US4642308A (pl)
EP (1) EP0172083B1 (pl)
JP (1) JPS6163656A (pl)
KR (1) KR860001100A (pl)
AT (1) ATE33652T1 (pl)
AU (1) AU572672B2 (pl)
CA (1) CA1224787A (pl)
CS (1) CS253730B2 (pl)
DD (1) DD240011A5 (pl)
DE (1) DE3562250D1 (pl)
DK (1) DK327285A (pl)
ES (1) ES8604584A1 (pl)
FI (1) FI79313C (pl)
FR (1) FR2567887B1 (pl)
GR (1) GR851774B (pl)
HU (1) HU199802B (pl)
IL (1) IL75817A (pl)
MA (1) MA20487A1 (pl)
NO (1) NO161673C (pl)
NZ (1) NZ212764A (pl)
OA (1) OA08069A (pl)
PH (1) PH21301A (pl)
PL (1) PL145331B1 (pl)
PT (1) PT80840B (pl)
SU (1) SU1417797A3 (pl)
YU (1) YU118785A (pl)
ZA (1) ZA855409B (pl)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1265803A (fr) * 1985-07-11 1990-02-13 Claude Cotrel Amides substitues, leur preparation et les medicaments qui les contiennent
FR2592882B2 (fr) * 1986-01-16 1988-03-11 Rhone Poulenc Sante Nouveaux amides substitues, leur preparation et les medicaments qui les contiennent
US4753941A (en) * 1986-01-16 1988-06-28 Rhone-Poulenc Sante Amides based on certain 1,8-naphtyridine-2-amines useful as anxiolytics
US5197518A (en) * 1991-06-27 1993-03-30 Double Containment Systems Centering support assembly for double containment pipe systems
GB9711257D0 (en) * 1997-05-30 1997-07-30 Smithkline Beecham Plc Novel compounds
AU777040B2 (en) * 1999-02-22 2004-09-30 Shire Biochem Inc. (1,8) naphthyridine derivatives having antiviral activity
JP4667384B2 (ja) * 2003-10-07 2011-04-13 レノビス， インコーポレイテッド イオンチャネルリガンドとしてのアミド誘導体および薬学的組成物、ならびにこれらを使用する方法
BRPI0606365A2 (pt) * 2005-02-28 2017-06-27 Renovis Inc composto ou um sal, solvato ou pró-droga farmaceuticamente aceitável do mesmo e estereoisômeros e tautômeros do mesmo, composição farmacêutica, métodos para prevenir, tratar, melhorar ou controlar uma doença ou condição e para preparar um composto, uso de um composto ou um sal, solvato ou composição farmaceuticamente aceitável do mesmo, método de tratamento de um mamífero, e, combinação
US7576099B2 (en) 2005-02-28 2009-08-18 Renovis, Inc. Amide derivatives as ion-channel ligands and pharmaceutical compositions and methods of using the same
WO2013090725A1 (en) * 2011-12-15 2013-06-20 Philadelphia Health & Education Corporation NOVEL PI3K p110 INHIBITORS AND METHODS OF USE THEREOF
CN105646487B (zh) * 2016-03-15 2017-12-05 红河学院 一类溴代1,8‑萘啶衍生物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB661515A (en) * 1948-08-31 1951-11-21 Cilag Ltd Process for the production of naphthyridine derivatives
FR1006725A (fr) * 1948-08-31 1952-04-28 Cilag Spa Nouveaux dérivés de la naphtyridine et procédé pour leur préparation
US3389142A (en) * 1966-09-29 1968-06-18 Bristol Myers Co Esters of 2-substituted 1, 2-dihydroquinoline-nu-carboxylic acids and thione acids
US3576809A (en) * 1968-05-06 1971-04-27 Miles Lab 2-substituted derivatives of 6-methoxyquinoline
US3624097A (en) * 1969-07-22 1971-11-30 Warner Lambert Co N-pyridine 5-aminooxazoles
US4466965A (en) * 1982-07-26 1984-08-21 American Hospital Supply Corporation Phthalazine compounds, compositions and use

Also Published As

Publication number Publication date
ES545336A0 (es) 1986-02-01
EP0172083B1 (fr) 1988-04-20
FI852821L (fi) 1986-01-20
ES8604584A1 (es) 1986-02-01
US4642308A (en) 1987-02-10
ZA855409B (en) 1986-04-30
NO161673C (no) 1989-09-13
DD240011A5 (de) 1986-10-15
PT80840B (pt) 1988-02-17
OA08069A (fr) 1987-03-31
FI79313B (fi) 1989-08-31
FR2567887B1 (fr) 1986-12-19
CA1224787A (fr) 1987-07-28
HUT40799A (en) 1987-02-27
DK327285A (da) 1986-01-20
CS253730B2 (en) 1987-12-17
GR851774B (pl) 1985-11-26
PT80840A (fr) 1985-08-01
NO161673B (no) 1989-06-05
EP0172083A1 (fr) 1986-02-19
FI79313C (fi) 1989-12-11
DK327285D0 (da) 1985-07-18
JPS6163656A (ja) 1986-04-01
PL145331B1 (en) 1988-09-30
ATE33652T1 (de) 1988-05-15
DE3562250D1 (en) 1988-05-26
AU572672B2 (en) 1988-05-12
IL75817A0 (en) 1985-11-29
NO852877L (no) 1986-01-20
FI852821A0 (fi) 1985-07-18
KR860001100A (ko) 1986-02-22
NZ212764A (en) 1988-05-30
FR2567887A1 (fr) 1986-01-24
SU1417797A3 (ru) 1988-08-15
PH21301A (en) 1987-09-28
AU4509085A (en) 1986-01-23
HU199802B (en) 1990-03-28
MA20487A1 (fr) 1986-04-01
PL254570A1 (en) 1986-10-21
YU118785A (en) 1988-10-31

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