IL75042A - 2,3-bis(3(r)-hydroxyalkanamido)-2,3-didesoxy-alpha-d-glucopyranose derivatives,their preparation and pharmaceutical compositions containing them - Google Patents
2,3-bis(3(r)-hydroxyalkanamido)-2,3-didesoxy-alpha-d-glucopyranose derivatives,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL75042A IL75042A IL75042A IL7504285A IL75042A IL 75042 A IL75042 A IL 75042A IL 75042 A IL75042 A IL 75042A IL 7504285 A IL7504285 A IL 7504285A IL 75042 A IL75042 A IL 75042A
- Authority
- IL
- Israel
- Prior art keywords
- pct
- hydroxyalkanamido
- didesoxy
- alpha
- bis
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- SUHOOTKUPISOBE-UHFFFAOYSA-N O-phosphoethanolamine Chemical compound NCCOP(O)(O)=O SUHOOTKUPISOBE-UHFFFAOYSA-N 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- VOBNSQKMDIOJTQ-UHFFFAOYSA-N 2-aminoethyl phosphono hydrogen phosphate Chemical group NCCOP(O)(=O)OP(O)(O)=O VOBNSQKMDIOJTQ-UHFFFAOYSA-N 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- XPPKVPWEQAFLFU-UHFFFAOYSA-J diphosphate(4-) Chemical compound [O-]P([O-])(=O)OP([O-])([O-])=O XPPKVPWEQAFLFU-UHFFFAOYSA-J 0.000 abstract 2
- 235000011180 diphosphates Nutrition 0.000 abstract 2
- 150000002431 hydrogen Chemical group 0.000 abstract 2
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
- 239000010452 phosphate Substances 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 229960001438 immunostimulant agent Drugs 0.000 abstract 1
- 239000003022 immunostimulating agent Substances 0.000 abstract 1
- 230000003308 immunostimulating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H5/00—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium
- C07H5/04—Compounds containing saccharide radicals in which the hetero bonds to oxygen have been replaced by the same number of hetero bonds to halogen, nitrogen, sulfur, selenium, or tellurium to nitrogen
- C07H5/06—Aminosugars
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/40—2,5-Pyrrolidine-diones
- C07D207/416—2,5-Pyrrolidine-diones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
- C07H11/04—Phosphates; Phosphites; Polyphosphates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
- C07H13/06—Fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/18—Acyclic radicals, substituted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19843415100 DE3415100A1 (de) | 1984-04-21 | 1984-04-21 | Neue 2,3-diamino-2,3-didesoxyhexosederivate, verfahren zu ihrer herstellung und ihre verwendung |
| DE19843415102 DE3415102A1 (de) | 1984-04-21 | 1984-04-21 | Neue 2,3-diamino-2,3-didesoxyhexosederivate, verfahren zu ihrer herstellung und ihre verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL75042A0 IL75042A0 (en) | 1985-08-30 |
| IL75042A true IL75042A (en) | 1989-05-15 |
Family
ID=25820628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL75042A IL75042A (en) | 1984-04-21 | 1985-04-29 | 2,3-bis(3(r)-hydroxyalkanamido)-2,3-didesoxy-alpha-d-glucopyranose derivatives,their preparation and pharmaceutical compositions containing them |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US4698331A (en:Method) |
| EP (1) | EP0180608B1 (en:Method) |
| AT (1) | ATE54920T1 (en:Method) |
| AU (1) | AU580061B2 (en:Method) |
| CA (1) | CA1264739A (en:Method) |
| DE (1) | DE3578866D1 (en:Method) |
| DK (1) | DK600585D0 (en:Method) |
| ES (1) | ES8605531A1 (en:Method) |
| FI (1) | FI81807C (en:Method) |
| GR (1) | GR850955B (en:Method) |
| HU (1) | HU197584B (en:Method) |
| IL (1) | IL75042A (en:Method) |
| NZ (1) | NZ211846A (en:Method) |
| PH (1) | PH23127A (en:Method) |
| PT (1) | PT80320B (en:Method) |
| WO (1) | WO1985004881A1 (en:Method) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU199494B (en) * | 1985-06-28 | 1990-02-28 | Sandoz Ag | Process for producing new saccharides and pharmaceutical compositions comprising same |
| DE3731953A1 (de) | 1987-09-23 | 1989-04-06 | Sandoz Ag | Neue saccharide, verfahren zu ihrer herstellung und ihre verwendung |
| US5219843A (en) * | 1987-09-23 | 1993-06-15 | Sandoz Ltd. | Saccharide derivatives |
| WO2001058920A2 (en) * | 2000-02-10 | 2001-08-16 | Mitsui Chemicals, Inc. | Process for selectively producing 1-phosphorylated sugar derivative anomer and process for producing nucleoside |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GR78246B (en:Method) * | 1981-01-23 | 1984-09-26 | Ciba Geigy Ag | |
| US4384998A (en) * | 1981-03-30 | 1983-05-24 | Merck & Co., Inc. | Synthesis of thienamycin from D-glucose |
| DE3220426A1 (de) * | 1982-05-29 | 1983-12-01 | Behringwerke Ag, 3550 Marburg | Chemische verbindung, verfahren zu ihrer herstellung und ihre verwendung zur bekaempfung der malaria |
| JPS60501259A (ja) * | 1983-05-06 | 1985-08-08 | ウイスコンシン・アルムニ・リサ−チ・フアンデ−シヨン | 免疫刺激活性をもつ単糖類化合物 |
| US4481196A (en) * | 1983-08-31 | 1984-11-06 | Fujisawa Pharmaceutical Co., Ltd. | Glycoside phosphate derivatives, pharmaceutical composition of the same and method of use |
| DE3347163A1 (de) * | 1983-12-27 | 1985-07-04 | Behringwerke Ag, 3550 Marburg | Verwendung von oligosacchariden zur chemotherapie oder chemoprophylaxe der malaria |
| US4481198A (en) * | 1984-02-13 | 1984-11-06 | Wisconsin Alumni Research Foundation | Vitamin D metabolism inhibitor |
-
1985
- 1985-04-17 HU HU852162A patent/HU197584B/hu not_active IP Right Cessation
- 1985-04-17 AT AT85902023T patent/ATE54920T1/de not_active IP Right Cessation
- 1985-04-17 EP EP85902023A patent/EP0180608B1/en not_active Expired - Lifetime
- 1985-04-17 US US06/815,097 patent/US4698331A/en not_active Expired - Fee Related
- 1985-04-17 DE DE8585902023T patent/DE3578866D1/de not_active Expired - Lifetime
- 1985-04-17 WO PCT/EP1985/000171 patent/WO1985004881A1/en not_active Ceased
- 1985-04-17 AU AU42380/85A patent/AU580061B2/en not_active Ceased
- 1985-04-19 PT PT80320A patent/PT80320B/pt not_active IP Right Cessation
- 1985-04-19 PH PH32164A patent/PH23127A/en unknown
- 1985-04-19 CA CA000479636A patent/CA1264739A/en not_active Expired - Lifetime
- 1985-04-19 GR GR850955A patent/GR850955B/el unknown
- 1985-04-19 ES ES542416A patent/ES8605531A1/es not_active Expired
- 1985-04-19 NZ NZ211846A patent/NZ211846A/xx unknown
- 1985-04-29 IL IL75042A patent/IL75042A/xx unknown
- 1985-12-20 FI FI855132A patent/FI81807C/fi not_active IP Right Cessation
- 1985-12-20 DK DK600585A patent/DK600585D0/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK600585A (da) | 1985-12-20 |
| DE3578866D1 (de) | 1990-08-30 |
| FI81807C (fi) | 1990-12-10 |
| EP0180608B1 (en) | 1990-07-25 |
| HUT42099A (en) | 1987-06-29 |
| EP0180608A1 (en) | 1986-05-14 |
| PH23127A (en) | 1989-05-05 |
| IL75042A0 (en) | 1985-08-30 |
| CA1264739A (en) | 1990-01-23 |
| GR850955B (en:Method) | 1985-11-25 |
| FI855132A0 (fi) | 1985-12-20 |
| ATE54920T1 (de) | 1990-08-15 |
| ES542416A0 (es) | 1986-03-16 |
| HU197584B (en) | 1989-04-28 |
| NZ211846A (en) | 1989-07-27 |
| FI81807B (fi) | 1990-08-31 |
| FI855132L (fi) | 1985-12-20 |
| DK600585D0 (da) | 1985-12-20 |
| ES8605531A1 (es) | 1986-03-16 |
| AU4238085A (en) | 1985-11-15 |
| US4698331A (en) | 1987-10-06 |
| PT80320A (en) | 1985-05-01 |
| AU580061B2 (en) | 1988-12-22 |
| WO1985004881A1 (en) | 1985-11-07 |
| PT80320B (en) | 1987-02-16 |
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