IL73904A - Benzoic acid derivatives and related compounds,their production and pharmaceutical compositions containing them - Google Patents
Benzoic acid derivatives and related compounds,their production and pharmaceutical compositions containing themInfo
- Publication number
- IL73904A IL73904A IL73904A IL7390484A IL73904A IL 73904 A IL73904 A IL 73904A IL 73904 A IL73904 A IL 73904A IL 7390484 A IL7390484 A IL 7390484A IL 73904 A IL73904 A IL 73904A
- Authority
- IL
- Israel
- Prior art keywords
- production
- pharmaceutical compositions
- benzoic acid
- compositions containing
- acid derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/14—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/06—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing isoquinuclidine ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH687983 | 1983-12-23 | ||
| CH687683 | 1983-12-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL73904A0 IL73904A0 (en) | 1985-03-31 |
| IL73904A true IL73904A (en) | 1989-09-10 |
Family
ID=25700317
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL73904A IL73904A (en) | 1983-12-23 | 1984-12-21 | Benzoic acid derivatives and related compounds,their production and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5001133A (fr) |
| AU (2) | AU586414B2 (fr) |
| BE (1) | BE901274A (fr) |
| CH (1) | CH666268A5 (fr) |
| DE (1) | DE3445377A1 (fr) |
| DK (1) | DK624784A (fr) |
| ES (1) | ES8704490A1 (fr) |
| FI (1) | FI845075L (fr) |
| FR (1) | FR2557110B1 (fr) |
| GB (1) | GB2152049B (fr) |
| GR (1) | GR82578B (fr) |
| HU (1) | HU193725B (fr) |
| IL (1) | IL73904A (fr) |
| IT (1) | IT1199243B (fr) |
| LU (1) | LU85687A1 (fr) |
| NL (1) | NL8403823A (fr) |
| PT (1) | PT79726A (fr) |
| SE (1) | SE8406585L (fr) |
| WO (1) | WO1985002847A1 (fr) |
Families Citing this family (74)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5122528A (en) * | 1983-12-22 | 1992-06-16 | Erbamont, Inc. | Analgesic use of benzobicyclic carboxamides |
| EP0385517B1 (fr) * | 1985-03-14 | 1993-04-14 | BEECHAM GROUP plc | Médicaments pour le traitement du vomissement |
| US4937247A (en) * | 1985-04-27 | 1990-06-26 | Beecham Group P.L.C. | 1-acyl indazoles |
| GB8623142D0 (en) * | 1986-09-26 | 1986-10-29 | Beecham Group Plc | Compounds |
| GB8515845D0 (en) * | 1985-06-22 | 1985-07-24 | Beecham Group Plc | Treatment |
| GB8516083D0 (en) * | 1985-06-25 | 1985-07-31 | Glaxo Group Ltd | Heterocyclic compounds |
| GB8520616D0 (en) * | 1985-08-16 | 1985-09-25 | Beecham Group Plc | Compounds |
| GB8523211D0 (en) * | 1985-09-19 | 1985-10-23 | Beecham Group Plc | Compounds |
| US4910193A (en) * | 1985-12-16 | 1990-03-20 | Sandoz Ltd. | Treatment of gastrointestinal disorders |
| DE3687980T2 (de) * | 1986-01-07 | 1993-06-17 | Beecham Group Plc | Indolderivate mit einer azabicyclischen seitenkette, verfahren zu ihrer herstellung, zwischenprodukte und pharmazeutische zusammensetzungen. |
| HU895334D0 (en) * | 1986-07-30 | 1990-01-28 | Sandoz Ag | Process for the preparation of nasal pharmaceutical compositions |
| AT396870B (de) * | 1986-08-07 | 1993-12-27 | Sandoz Ag | Verfahren zur herstellung einer galenischen formulierung zur nasalen verabreichung von serotoninantagonisten |
| EP0551963A3 (en) * | 1986-12-17 | 1993-09-01 | Glaxo Group Limited | Use of heterocyclic derivatives for the manufacture of medicaments |
| JP2608078B2 (ja) * | 1986-12-17 | 1997-05-07 | グラクソ、グループ、リミテッド | 医 薬 |
| DE3788057T2 (de) * | 1986-12-17 | 1994-03-03 | Glaxo Group Ltd | Verwendung von heterocyclischen Verbindungen zur Behandlung von Depressionen. |
| GB8806990D0 (en) * | 1988-03-23 | 1988-04-27 | Beecham Group Plc | Novel compounds |
| GB8701022D0 (en) * | 1987-01-19 | 1987-02-18 | Beecham Group Plc | Treatment |
| DE3852145T2 (de) * | 1987-02-18 | 1995-04-06 | Beecham Group Plc | Indolderivate, Verfahren zu deren Herstellung und pharmazeutische Präparate, die diese enthalten. |
| DE3822792C2 (de) * | 1987-07-11 | 1997-11-27 | Sandoz Ag | Neue Verwendung von 5HT¶3¶-Antagonisten |
| US5364863A (en) * | 1987-09-08 | 1994-11-15 | Eli Lilly And Company | Specific 5-HT3 antagonists |
| US4921982A (en) * | 1988-07-21 | 1990-05-01 | Eli Lilly And Company | 5-halo-2,3-dihydro-2,2-dimethylbenzofuran-7-carboxylic acids useful as intermediates for 5-HT3 antagonists |
| US5011846A (en) * | 1988-02-23 | 1991-04-30 | Merrell Dow Pharmaceuticals Inc. | Medicament compositions derived from quinolizine and quinolizinone and methods of use thereof |
| DE68924545T2 (de) * | 1988-02-23 | 1996-03-21 | Merrell Dow Pharma | Verwendung von Chinolizin- und Chinolizinon-Derivaten zur Herstellung von Arzneimitteln. |
| GB8814277D0 (en) * | 1988-06-16 | 1988-07-20 | Glaxo Group Ltd | Chemical compounds |
| US5126343A (en) * | 1989-09-11 | 1992-06-30 | G. D. Searle & Co. | N-azabicyclo [3.3.0]octane amides of aromatic acids |
| CA2030051C (fr) * | 1989-11-17 | 2001-08-07 | Haruhiko Kikuchi | Derives indole |
| GB8928837D0 (en) * | 1989-12-21 | 1990-02-28 | Beecham Group Plc | Pharmaceuticals |
| US5223613A (en) * | 1990-04-27 | 1993-06-29 | G. D. Searle & Co. | Azatetracycle compounds and process of preparing same |
| US5140023A (en) * | 1990-04-27 | 1992-08-18 | G. D. Searle & Co. | Azatetracycle compounds |
| US5187166A (en) * | 1990-07-31 | 1993-02-16 | Nisshin Flour Milling Co., Ltd. | Azabicyclo derivatives and their use as antiemetics |
| JP3026845B2 (ja) * | 1991-02-20 | 2000-03-27 | 日清製粉株式会社 | ピペリジン誘導体 |
| GB9103862D0 (en) * | 1991-02-25 | 1991-04-10 | Glaxo Group Ltd | Chemical compounds |
| US5227377A (en) * | 1991-03-07 | 1993-07-13 | G. D. Searle & Co. | Meso-azacyclic amides of certain bicyclic carboxylic acids |
| US5260303A (en) * | 1991-03-07 | 1993-11-09 | G. D. Searle & Co. | Imidazopyridines as serotonergic 5-HT3 antagonists |
| US5516782A (en) * | 1991-03-07 | 1996-05-14 | G. D. Searle & Co. | New meso-azacyclic aromatic acid amides and esters as novel serotonergic agents |
| US5137893A (en) * | 1991-03-07 | 1992-08-11 | G. D. Searle & Co. | Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
| US5234921A (en) * | 1991-03-07 | 1993-08-10 | G. D. Searle & Co. | Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof as pharmaceuticals |
| EP0528026A1 (fr) * | 1991-03-07 | 1993-02-24 | G.D. Searle & Co. | Nouveaux amides et esters d'acides aromatiques meso-azacycliques servant de nouveaux agents serotonergiques |
| US5196547A (en) * | 1991-03-07 | 1993-03-23 | G. D. Searle & Co. | Meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
| US5219850A (en) * | 1991-03-07 | 1993-06-15 | G. D. Searle & Co. | Pharmaceutically useful meso-azacyclic amides of imidazopyridine carboxylic acids and analogs thereof |
| EP1082959A1 (fr) | 1991-09-20 | 2001-03-14 | Glaxo Group Limited | Utilisation des NK1-antagonistes pour le traitement de la depression |
| US5314899A (en) * | 1992-03-03 | 1994-05-24 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Epibatidine and derivatives, compositions and methods of treating pain |
| US5998409A (en) * | 1992-03-12 | 1999-12-07 | Smithkline Beecham Plc | Condensed indole derivatives as 5HT4 -receptor antagonists |
| US5852014A (en) * | 1992-03-12 | 1998-12-22 | Smithkline Beecham P.L.C. | Condensed indole derivatives as 5HT4 -receptor antagonists |
| JP2699794B2 (ja) * | 1992-03-12 | 1998-01-19 | 三菱化学株式会社 | チエノ〔3,2−b〕ピリジン誘導体 |
| US5236931A (en) * | 1992-03-26 | 1993-08-17 | A. H. Robins Company, Incorporated | 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol |
| US5840903A (en) | 1992-07-27 | 1998-11-24 | G. D. Searle & Co. | 4-aminomethyl-1-azaadamantane derived benzamides |
| US5354757A (en) * | 1992-12-15 | 1994-10-11 | G. D. Searle & Co. | Azanoradamantanes |
| JP3235913B2 (ja) * | 1993-07-30 | 2001-12-04 | エーザイ株式会社 | アミノ安息香酸誘導体 |
| US5399562A (en) * | 1994-02-04 | 1995-03-21 | G. D. Searle & Co. | Indolones useful as serotonergic agents |
| US5530018A (en) * | 1994-02-04 | 1996-06-25 | G. D. Searle & Co. | Meso-azanoradamantanes |
| AU708112B2 (en) * | 1994-08-25 | 1999-07-29 | University Of Virginia | 7-azabicyclo{2.2.1}-heptane and -heptene derivatives as cholinergic receptor ligands |
| AR036040A1 (es) | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen |
| AR036041A1 (es) * | 2001-06-12 | 2004-08-04 | Upjohn Co | Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen |
| EP1425286B1 (fr) * | 2001-09-12 | 2007-02-28 | Pharmacia & Upjohn Company LLC | 7-aza-[2.2.1]-bicycloheptanes substitues pour le traitement de maladies |
| US6858613B2 (en) * | 2002-02-19 | 2005-02-22 | Pfizer Inc. | Fused bicyclic-N-bridged-heteroaromatic carboxamides for the treatment of disease |
| BR0307782A (pt) * | 2002-02-19 | 2005-01-04 | Upjohn Co | Compostos azabiciclo para o tratamento de doença |
| CA2503786A1 (fr) * | 2002-11-01 | 2004-05-13 | Pharmacia & Upjohn Company Llc | Composes possedant une activite d'agoniste du recepteur nicotinique alpha7 et d'antagoniste du recepteur 5ht3 pour traiter des maladies du systeme nerveux central |
| US8138342B2 (en) * | 2004-10-12 | 2012-03-20 | High Point Pharmacueticals, LLC | 11β-hydroxysteroid dehydrogenase type 1 active spiro compounds |
| KR20080076916A (ko) * | 2005-11-01 | 2008-08-20 | 트랜스테크 파르마, 인크. | 치환된 아미드의 약학적 사용 |
| JP2009513611A (ja) * | 2005-11-01 | 2009-04-02 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 置換アミドの医薬用途 |
| EP2007722A1 (fr) * | 2006-03-21 | 2008-12-31 | High Point Pharmaceuticals, LLC | Dérivés d'adamantane pour le traitement du syndrome métabolique |
| KR20090014347A (ko) | 2006-04-07 | 2009-02-10 | 하이 포인트 파마슈티칼스, 엘엘씨 | 11β-히드록시스테로이드 탈수소효소 타입 1 활성 화합물 |
| JP2009539937A (ja) * | 2006-06-16 | 2009-11-19 | ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー | 置換型ピペリジンカルボキサミドの医薬的使用 |
| US8048908B2 (en) * | 2006-07-13 | 2011-11-01 | High Point Pharmaceuticals, Llc | 11β-hydroxysteroid dehydrogenase type 1 active compounds |
| EP1878721A1 (fr) * | 2006-07-13 | 2008-01-16 | Novo Nordisk A/S | 4-Piperidylbenzamides en tant qu'inhibiteurs de la 11-beta-hydroxysteroid dehydrogenase type 1 |
| CA2675669C (fr) * | 2007-02-23 | 2015-05-26 | High Point Pharmaceuticals, Llc | Nouveaux composes |
| EP2125704A1 (fr) * | 2007-02-23 | 2009-12-02 | High Point Pharmaceuticals, LLC | N-adamantyl benzamides utilisés en tant qu'inhibiteurs de la 11-bêta-hydroxystéroïde déshydrogénase |
| US8334305B2 (en) * | 2007-02-23 | 2012-12-18 | High Point Pharmaceuticals, Llc | N-adamantyl benzamides as inhibitors of 11-β-hydroxysteroid dehydrogenase |
| WO2008101885A1 (fr) * | 2007-02-23 | 2008-08-28 | High Point Pharmaceuticals, Llc | Nouveaux composés |
| CN101652359A (zh) * | 2007-03-09 | 2010-02-17 | 高点制药有限责任公司 | 作为羟类固醇脱氢酶抑制剂的吲哚-和苯并咪唑酰胺类 |
| CA2681934A1 (fr) * | 2007-03-28 | 2008-10-02 | High Point Pharmaceuticals, Llc | Composes actifs sur 11beta-hsd1 |
| WO2008127924A1 (fr) * | 2007-04-11 | 2008-10-23 | High Point Pharmaceuticals, Llc. | Nouveaux composés |
| US8383683B2 (en) * | 2007-04-24 | 2013-02-26 | High Point Pharmaceuticals, Llc | Pharmaceutical use of substituted amides |
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|---|---|---|---|---|
| US2748134A (en) * | 1956-05-29 | Amide-like derivatives of piperidine | ||
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| GB232207A (en) * | 1924-04-08 | 1926-02-18 | Hermann Staudinger | Manufacture of derivatives of 4-oxypiperidine |
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| NL281394A (fr) * | 1961-07-25 | |||
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| US3405134A (en) * | 1965-08-17 | 1968-10-08 | Colgate Palmolive Co | Quinuclidyl esters of aromatic acids |
| NL133069C (fr) * | 1966-07-29 | |||
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| US3577440A (en) * | 1968-12-23 | 1971-05-04 | Robins Co Inc A H | 1-substituted-3-amido-pyrrolidines |
| US3702324A (en) * | 1970-06-24 | 1972-11-07 | Stanford Research Inst | 3,4,5-trimethoxybenzamides of substituted anilines and of alkylpiperidines |
| GB1507462A (en) * | 1974-03-21 | 1978-04-12 | Gallardo Antonio Sa | N-heterocyclic substituted benzamides methods for their preparation and compositions containing them |
| DE2434547A1 (de) * | 1974-07-18 | 1976-01-29 | Hoechst Ag | Beta-acyloxy-crotonsaeureamid-nsulfohalogenide, verfahren zu ihrer herstellung und ihre ueberfuehrung in suesstoffe |
| US4093734A (en) * | 1975-11-03 | 1978-06-06 | Boehringer Ingelheim Gmbh | Amino-benzoic acid amides |
| DE2557341A1 (de) * | 1975-12-19 | 1977-06-30 | Hoechst Ag | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
| DE2557342A1 (de) * | 1975-12-19 | 1977-06-30 | Hoechst Ag | Basisch substituierte indolderivate und verfahren zu ihrer herstellung |
| GB1593146A (en) * | 1976-11-05 | 1981-07-15 | Beecham Group Ltd | Octahydro-quinolizinyl benzamide derivatives |
| NZ186175A (en) * | 1977-01-27 | 1980-03-05 | Shionogi & Co | Meta-sulphonamidobenzamide derivatives |
| GB2037740B (en) * | 1978-12-21 | 1982-11-10 | Yamanouchi Pharma Co Ltd | Benzamide derivatives |
| IL59004A0 (en) * | 1978-12-30 | 1980-03-31 | Beecham Group Ltd | Substituted benzamides their preparation and pharmaceutical compositions containing them |
| FR2476088A2 (fr) * | 1979-01-16 | 1981-08-21 | Delalande Sa | Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique |
| NZ197356A (en) * | 1980-06-18 | 1984-05-31 | Beecham Group Ltd | Ar-alkylsulphinyl-n-(azaicycloalkyl(alkyl)) benzamides |
| FR2493848B2 (fr) * | 1980-11-07 | 1986-05-16 | Delalande Sa | Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique |
| US4470977A (en) * | 1981-06-04 | 1984-09-11 | Adria Laboratories, Inc. | Antiemetic and antipsychotic agents |
| CA1220141A (fr) * | 1981-06-13 | 1987-04-07 | John R. Fozard | Traitement de la migraine avec des derives de benzoate de tropyle |
| EP0067615B1 (fr) * | 1981-06-17 | 1986-01-08 | Beecham Group Plc | Dérivés thioalkyl d'azabicyclobenzamides, leur procédé de préparation et les compositions pharmaceutiques les contenant |
| EP0068700A1 (fr) * | 1981-06-29 | 1983-01-05 | Beecham Group Plc | Azabicycloalkylbenzamides, leur procédé de préparation et les compositions pharmaceutiques les contenant |
| EP0069482A1 (fr) * | 1981-06-29 | 1983-01-12 | Beecham Group Plc | Azabicycloalkylenzamides, leur procédé de préparation et les compositions pharmaceutiques les contenant |
| FR2514006A1 (fr) * | 1981-10-05 | 1983-04-08 | Nativelle Sa Ets | Acylamino-4 aza-1 adamantanes, procede pour leur preparation, et application en therapeutique |
| IE56226B1 (en) * | 1982-04-14 | 1991-05-22 | Beecham Group Plc | Substituted azabicyclo compounds,process for their preparation and pharmaceutical compositions containing them |
| FR2531083B1 (fr) * | 1982-06-29 | 1986-11-28 | Sandoz Sa | Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments |
| BE897117A (fr) * | 1982-06-29 | 1983-12-23 | Sandoz Sa | Nouveaux derives de la piperidine leur preparation et leur utilisation comme medicaments |
| JPS5936675A (ja) * | 1982-07-13 | 1984-02-28 | サンド・アクチエンゲゼルシヤフト | 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド |
| GB2131794B (en) * | 1982-12-10 | 1986-04-03 | Merrell Toraude & Co | Treatment of migraine with n-alkyl-piperidinyl benzoate derivatives |
| EP0135545A1 (fr) * | 1983-02-19 | 1985-04-03 | Beecham Group Plc | Derives anylides et benzamides d'azabicycloalkyle |
| DE3429830A1 (de) * | 1983-08-26 | 1985-03-07 | Sandoz-Patent-GmbH, 7850 Lörrach | Automatische carbonsaeure- und sulfonsaeureester oder -amide |
| ES2102045T3 (es) * | 1992-07-10 | 1997-07-16 | Du Pont | Composiciones azeotropicas de perfluoroetano y trifluorometano. |
-
1984
- 1984-12-13 FR FR8419243A patent/FR2557110B1/fr not_active Expired
- 1984-12-13 DE DE19843445377 patent/DE3445377A1/de not_active Withdrawn
- 1984-12-14 HU HU844681A patent/HU193725B/hu not_active IP Right Cessation
- 1984-12-14 WO PCT/CH1984/000196 patent/WO1985002847A1/fr not_active Ceased
- 1984-12-14 CH CH3601/85A patent/CH666268A5/de not_active IP Right Cessation
- 1984-12-14 BE BE1/11152A patent/BE901274A/fr not_active IP Right Cessation
- 1984-12-17 NL NL8403823A patent/NL8403823A/nl not_active Application Discontinuation
- 1984-12-18 LU LU85687A patent/LU85687A1/fr unknown
- 1984-12-20 GB GB08432184A patent/GB2152049B/en not_active Expired
- 1984-12-20 FI FI845075A patent/FI845075L/fi not_active Application Discontinuation
- 1984-12-21 SE SE8406585A patent/SE8406585L/xx not_active Application Discontinuation
- 1984-12-21 ES ES538958A patent/ES8704490A1/es not_active Expired
- 1984-12-21 GR GR82578A patent/GR82578B/el unknown
- 1984-12-21 DK DK624784A patent/DK624784A/da not_active Application Discontinuation
- 1984-12-21 PT PT79726A patent/PT79726A/pt unknown
- 1984-12-21 IL IL73904A patent/IL73904A/xx unknown
- 1984-12-21 IT IT49339/84A patent/IT1199243B/it active
- 1984-12-21 AU AU37073/84A patent/AU586414B2/en not_active Ceased
-
1988
- 1988-11-04 US US07/267,062 patent/US5001133A/en not_active Expired - Fee Related
-
1989
- 1989-05-05 AU AU34090/89A patent/AU3409089A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES538958A0 (es) | 1987-04-01 |
| GB8432184D0 (en) | 1985-01-30 |
| HU193725B (en) | 1987-11-30 |
| ES8704490A1 (es) | 1987-04-01 |
| IT8449339A0 (it) | 1984-12-21 |
| IL73904A0 (en) | 1985-03-31 |
| CH666268A5 (de) | 1988-07-15 |
| FI845075A0 (fi) | 1984-12-20 |
| NL8403823A (nl) | 1985-07-16 |
| AU3707384A (en) | 1985-07-04 |
| AU3409089A (en) | 1989-09-21 |
| PT79726A (en) | 1985-01-01 |
| SE8406585D0 (sv) | 1984-12-21 |
| SE8406585L (sv) | 1985-06-24 |
| US5001133A (en) | 1991-03-19 |
| FR2557110A1 (fr) | 1985-06-28 |
| HUT38341A (en) | 1986-05-28 |
| GB2152049B (en) | 1988-06-15 |
| BE901274A (fr) | 1985-06-14 |
| FR2557110B1 (fr) | 1989-11-24 |
| DK624784D0 (da) | 1984-12-21 |
| IT1199243B (it) | 1988-12-30 |
| DE3445377A1 (de) | 1985-07-04 |
| DK624784A (da) | 1985-06-24 |
| WO1985002847A1 (fr) | 1985-07-04 |
| AU586414B2 (en) | 1989-07-13 |
| FI845075A7 (fi) | 1985-06-24 |
| GB2152049A (en) | 1985-07-31 |
| LU85687A1 (fr) | 1985-09-12 |
| FI845075L (fi) | 1985-06-24 |
| GR82578B (en) | 1985-04-23 |
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