IL73255A - 2-mercapto-5-hydroxymethyl-imidazole derivatives and their preparation - Google Patents

2-mercapto-5-hydroxymethyl-imidazole derivatives and their preparation

Info

Publication number
IL73255A
IL73255A IL73255A IL7325584A IL73255A IL 73255 A IL73255 A IL 73255A IL 73255 A IL73255 A IL 73255A IL 7325584 A IL7325584 A IL 7325584A IL 73255 A IL73255 A IL 73255A
Authority
IL
Israel
Prior art keywords
mercapto
formula
hydroxymethyl
preparation
imidazole derivatives
Prior art date
Application number
IL73255A
Other languages
English (en)
Other versions
IL73255A0 (en
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Publication of IL73255A0 publication Critical patent/IL73255A0/xx
Publication of IL73255A publication Critical patent/IL73255A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Resins (AREA)
  • Cephalosporin Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
IL73255A 1983-10-18 1984-10-16 2-mercapto-5-hydroxymethyl-imidazole derivatives and their preparation IL73255A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI833794A FI833794A0 (fi) 1983-10-18 1983-10-18 Substituerade 2-merkapto-imidazoler

Publications (2)

Publication Number Publication Date
IL73255A0 IL73255A0 (en) 1985-01-31
IL73255A true IL73255A (en) 1988-11-30

Family

ID=8517935

Family Applications (1)

Application Number Title Priority Date Filing Date
IL73255A IL73255A (en) 1983-10-18 1984-10-16 2-mercapto-5-hydroxymethyl-imidazole derivatives and their preparation

Country Status (18)

Country Link
US (1) US4584383A (de)
EP (1) EP0146228B1 (de)
JP (1) JPS60149568A (de)
AT (1) ATE32064T1 (de)
AU (1) AU566437B2 (de)
DD (1) DD236730A1 (de)
DE (1) DE3468869D1 (de)
DK (1) DK174201B1 (de)
ES (1) ES536186A0 (de)
FI (1) FI833794A0 (de)
HU (1) HU191960B (de)
IE (1) IE57591B1 (de)
IL (1) IL73255A (de)
NO (1) NO159167C (de)
NZ (1) NZ209896A (de)
SU (1) SU1301313A3 (de)
UA (1) UA5972A1 (de)
ZA (1) ZA848112B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634711A (en) * 1985-08-02 1987-01-06 Smithkline Beckman Corporation Pyridylalkyl imidazole-2-thiols
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
US4882348A (en) * 1987-12-29 1989-11-21 Smithkline Beckman Corporation 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US5210079A (en) * 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
US5354867A (en) * 1988-12-06 1994-10-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
KR950009860B1 (ko) * 1989-06-30 1995-08-29 이. 아이. 듀퐁 드 네모아 앤드 캄파니 융합된 환 아릴 치환된 이미다졸과 약제학적으로 허용되는 이의 염, 이들의 제조방법 및 이들을 함유하는 약제학적 조성물
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5332820A (en) * 1991-05-20 1994-07-26 E. I. Du Pont De Nemours And Company Dibenzobicyclo(2.2.2) octane angiotensin II antagonists
US5612360A (en) * 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
IT1295405B1 (it) 1997-09-30 1999-05-12 Merck Sharp & Dohme Italia S P Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di
KR100567183B1 (ko) * 1997-11-14 2006-06-13 론자 아게 포르밀이미다졸의제조방법
JP2003508521A (ja) 1999-09-06 2003-03-04 エルジー シーアイ リミテッド １位で置換された５−ヒドロキシメチルイミダゾールの製造方法
KR100388788B1 (ko) * 1999-09-06 2003-06-25 주식회사 엘지생명과학 1-치환된-5-하이드록시메틸 이미다졸의 신규 제조방법
US6620939B2 (en) 2001-09-18 2003-09-16 General Electric Company Method for producing bisphenol catalysts and bisphenols
US7112702B2 (en) * 2002-12-12 2006-09-26 General Electric Company Process for the synthesis of bisphenol
FI116292B (fi) 2003-01-08 2005-10-31 Juvantia Pharma Ltd Oy Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita
US7132575B2 (en) * 2003-07-01 2006-11-07 General Electric Company Process for the synthesis of bisphenol
FI20050391A0 (fi) * 2005-04-15 2005-04-15 Orion Corp Detomidiinihydrokloridin kiteytysmenetelmä
CN101747280B (zh) * 2008-11-28 2011-11-09 上海迪赛诺医药发展有限公司 制备地托咪定及其中间体的方法
WO2020016827A1 (en) 2018-07-18 2020-01-23 Clexio Biosciences Ltd. Purified crystalline detomidine hydrochloride monohydrate, anhydrate and free base with low amounts of iso-detomidine and other impurities by recrystallisation in water
EP3782989A1 (de) 2019-08-23 2021-02-24 Andreas Sachse Detomidin-hydrochlorid-monohydrat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2541924A (en) * 1948-09-17 1951-02-13 Lilly Co Eli Synthesis of substituted imidazoles
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
DK174201B1 (da) 2002-09-16
DD236730A1 (de) 1986-06-18
FI833794A0 (fi) 1983-10-18
US4584383A (en) 1986-04-22
EP0146228A1 (de) 1985-06-26
ZA848112B (en) 1985-06-26
DK471384A (da) 1985-04-19
EP0146228B1 (de) 1988-01-20
IL73255A0 (en) 1985-01-31
IE57591B1 (en) 1993-01-13
AU3426384A (en) 1985-04-26
JPS60149568A (ja) 1985-08-07
UA5972A1 (uk) 1994-12-29
AU566437B2 (en) 1987-10-22
NZ209896A (en) 1987-02-20
ES8507507A1 (es) 1985-09-01
DE3468869D1 (en) 1988-02-25
NO844139L (no) 1985-04-19
NO159167B (no) 1988-08-29
IE842652L (en) 1985-04-18
HU191960B (en) 1987-04-28
DK471384D0 (da) 1984-10-02
SU1301313A3 (ru) 1987-03-30
HUT35649A (en) 1985-07-29
ATE32064T1 (de) 1988-02-15
ES536186A0 (es) 1985-09-01
NO159167C (no) 1988-12-07

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Legal Events

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