FI833794A0 - Substituerade 2-merkapto-imidazoler - Google Patents

Substituerade 2-merkapto-imidazoler

Info

Publication number
FI833794A0
FI833794A0 FI833794A FI833794A FI833794A0 FI 833794 A0 FI833794 A0 FI 833794A0 FI 833794 A FI833794 A FI 833794A FI 833794 A FI833794 A FI 833794A FI 833794 A0 FI833794 A0 FI 833794A0
Authority
FI
Finland
Prior art keywords
formula
group
compounds
image
aldehyde
Prior art date
Application number
FI833794A
Other languages
English (en)
Finnish (fi)
Inventor
Seppo S L Parhi
Original Assignee
Farmos Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Farmos Oy filed Critical Farmos Oy
Priority to FI833794A priority Critical patent/FI833794A0/fi
Publication of FI833794A0 publication Critical patent/FI833794A0/fi
Priority to ES536186A priority patent/ES536186A0/es
Priority to DK198404713A priority patent/DK174201B1/da
Priority to DD84268430A priority patent/DD236730A1/de
Priority to AU34263/84A priority patent/AU566437B2/en
Priority to US06/661,487 priority patent/US4584383A/en
Priority to JP59218160A priority patent/JPS60149568A/ja
Priority to IL73255A priority patent/IL73255A/xx
Priority to DE8484307095T priority patent/DE3468869D1/de
Priority to IE2652/84A priority patent/IE57591B1/en
Priority to NZ209896A priority patent/NZ209896A/en
Priority to AT84307095T priority patent/ATE32064T1/de
Priority to EP84307095A priority patent/EP0146228B1/de
Priority to UA3801008A priority patent/UA5972A1/uk
Priority to FI844079A priority patent/FI69302C/fi
Priority to NO844139A priority patent/NO159167C/no
Priority to HU843890A priority patent/HU191960B/hu
Priority to ZA848112A priority patent/ZA848112B/xx
Priority to SU843801008A priority patent/SU1301313A3/ru
Priority to LV920317A priority patent/LV5065A3/xx
Priority to LTRP767A priority patent/LT2219B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Epoxy Resins (AREA)
  • Cephalosporin Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI833794A 1983-10-18 1983-10-18 Substituerade 2-merkapto-imidazoler FI833794A0 (fi)

Priority Applications (21)

Application Number Priority Date Filing Date Title
FI833794A FI833794A0 (fi) 1983-10-18 1983-10-18 Substituerade 2-merkapto-imidazoler
ES536186A ES536186A0 (es) 1983-10-18 1984-09-24 Un procedimiento para preparar 5-hidroximetil-2-mercapto-imidazoles sustituidos en posicion 1
DK198404713A DK174201B1 (da) 1983-10-18 1984-10-02 Substituerede 2-mercoptoimidazoler eller syreadditionssalte deraf samt fremgangsmåde til fremstilling af disse forbindelser
AU34263/84A AU566437B2 (en) 1983-10-18 1984-10-16 Substituted-2-mercapto-imidazoles
DE8484307095T DE3468869D1 (en) 1983-10-18 1984-10-16 Substituted 2-mercapto-imidazoles and their preparation and use
EP84307095A EP0146228B1 (de) 1983-10-18 1984-10-16 Substituierte 2-Mercapto-Imidazole und deren Herstellung und Anwendung
US06/661,487 US4584383A (en) 1983-10-18 1984-10-16 Substituted 2-mercapto-imidazoles and their preparation
JP59218160A JPS60149568A (ja) 1983-10-18 1984-10-16 1−置換−5−ヒドロキシメチル−2−メルカプト−イミダゾ−ル類およびその製法
IL73255A IL73255A (en) 1983-10-18 1984-10-16 2-mercapto-5-hydroxymethyl-imidazole derivatives and their preparation
DD84268430A DD236730A1 (de) 1983-10-18 1984-10-16 Verfahren zur herstellung von 1-substituierten 5-hydroxymethyl-2-merkapto-imidazolen
IE2652/84A IE57591B1 (en) 1983-10-18 1984-10-16 Substituted 2-mercapto-imidazoles and their preparation and use
NZ209896A NZ209896A (en) 1983-10-18 1984-10-16 5-hydroxymethyl-2-mercapto-imidazoles preparation of 5-formyl-imidazoles
AT84307095T ATE32064T1 (de) 1983-10-18 1984-10-16 Substituierte 2-mercapto-imidazole und deren herstellung und anwendung.
UA3801008A UA5972A1 (uk) 1983-10-18 1984-10-17 Спосіб отримання заміщених 2-меркапто-імідазолів
SU843801008A SU1301313A3 (ru) 1983-10-18 1984-10-17 Способ получени замещенных 2-меркапто-имидазолов
FI844079A FI69302C (fi) 1983-10-18 1984-10-17 1-substituerade 5-hydroximetyl-2-merkapto-imidazoler
NO844139A NO159167C (no) 1983-10-18 1984-10-17 Nye 1-substituerte-5-hydroksymetyl-2-merkapto-imidazol-derivater og fremgangsmaate for fremstilling derav.
HU843890A HU191960B (en) 1983-10-18 1984-10-17 Process for preparing substituted 2-mercapto-imidazoles
ZA848112A ZA848112B (en) 1983-10-18 1984-10-17 Substituted 2-mercapto-imidazoles and their perparation and use
LV920317A LV5065A3 (lv) 1983-10-18 1992-12-17 Aizvietotu 2-merkapto-imidazolu iegusanas metode
LTRP767A LT2219B (lt) 1983-10-18 1993-07-07 Pavaduotu 2-merkapto-imidazolu gavimo budas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FI833794A FI833794A0 (fi) 1983-10-18 1983-10-18 Substituerade 2-merkapto-imidazoler

Publications (1)

Publication Number Publication Date
FI833794A0 true FI833794A0 (fi) 1983-10-18

Family

ID=8517935

Family Applications (1)

Application Number Title Priority Date Filing Date
FI833794A FI833794A0 (fi) 1983-10-18 1983-10-18 Substituerade 2-merkapto-imidazoler

Country Status (18)

Country Link
US (1) US4584383A (de)
EP (1) EP0146228B1 (de)
JP (1) JPS60149568A (de)
AT (1) ATE32064T1 (de)
AU (1) AU566437B2 (de)
DD (1) DD236730A1 (de)
DE (1) DE3468869D1 (de)
DK (1) DK174201B1 (de)
ES (1) ES536186A0 (de)
FI (1) FI833794A0 (de)
HU (1) HU191960B (de)
IE (1) IE57591B1 (de)
IL (1) IL73255A (de)
NO (1) NO159167C (de)
NZ (1) NZ209896A (de)
SU (1) SU1301313A3 (de)
UA (1) UA5972A1 (de)
ZA (1) ZA848112B (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4634711A (en) * 1985-08-02 1987-01-06 Smithkline Beckman Corporation Pyridylalkyl imidazole-2-thiols
US5138069A (en) * 1986-07-11 1992-08-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
US4882348A (en) * 1987-12-29 1989-11-21 Smithkline Beckman Corporation 2-(aminoalkylthio)imidazoles as dopamine-β-hydroxylase inhibitors
US5210079A (en) * 1988-01-07 1993-05-11 E. I. Du Pont De Nemours And Company Treatment of chronic renal failure with imidazole angiotensin-II receptor antagonists
US4880804A (en) * 1988-01-07 1989-11-14 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking benzimidazoles
CA1338238C (en) 1988-01-07 1996-04-09 David John Carini Angiotensin ii receptor blocking imidazoles and combinations thereof with diuretics and nsaids
US5354867A (en) * 1988-12-06 1994-10-11 E. I. Du Pont De Nemours And Company Angiotensin II receptor blocking imidazoles
KR950009860B1 (ko) * 1989-06-30 1995-08-29 이. 아이. 듀퐁 드 네모아 앤드 캄파니 융합된 환 아릴 치환된 이미다졸과 약제학적으로 허용되는 이의 염, 이들의 제조방법 및 이들을 함유하는 약제학적 조성물
US5073566A (en) * 1989-11-30 1991-12-17 Eli Lilly And Company Angiotensin ii antagonist 1,3-imidazoles and use thereas
US5332820A (en) * 1991-05-20 1994-07-26 E. I. Du Pont De Nemours And Company Dibenzobicyclo(2.2.2) octane angiotensin II antagonists
US5612360A (en) * 1992-06-03 1997-03-18 Eli Lilly And Company Angiotensin II antagonists
US5401851A (en) * 1992-06-03 1995-03-28 Eli Lilly And Company Angiotensin II antagonists
IT1295405B1 (it) 1997-09-30 1999-05-12 Merck Sharp & Dohme Italia S P Uso di un antagonista recettoriale di angiotensina ii per la preparazione di farmaci per aumentare il tasso di sopravvivenza di
KR100567183B1 (ko) * 1997-11-14 2006-06-13 론자 아게 포르밀이미다졸의제조방법
AU7040500A (en) 1999-09-06 2001-04-10 Lg Chem Investment Ltd. Process for preparing a 1-substituted 5-hydroxymethyl imidazole
KR100388788B1 (ko) * 1999-09-06 2003-06-25 주식회사 엘지생명과학 1-치환된-5-하이드록시메틸 이미다졸의 신규 제조방법
US6620939B2 (en) * 2001-09-18 2003-09-16 General Electric Company Method for producing bisphenol catalysts and bisphenols
US7112702B2 (en) * 2002-12-12 2006-09-26 General Electric Company Process for the synthesis of bisphenol
FI116292B (fi) 2003-01-08 2005-10-31 Juvantia Pharma Ltd Oy Menetelmä substituoitujen imidatsolijohdannaisten valmistamiseksi ja menetelmässä käytettäviä välituotteita
US7132575B2 (en) * 2003-07-01 2006-11-07 General Electric Company Process for the synthesis of bisphenol
FI20050391A0 (fi) * 2005-04-15 2005-04-15 Orion Corp Detomidiinihydrokloridin kiteytysmenetelmä
CN101747280B (zh) * 2008-11-28 2011-11-09 上海迪赛诺医药发展有限公司 制备地托咪定及其中间体的方法
US20210323929A1 (en) 2018-07-18 2021-10-21 Clexio Biosciences Ltd. Purified Detomidine, Process of Preparing and Methods of Use
EP3782989A1 (de) 2019-08-23 2021-02-24 Andreas Sachse Detomidin-hydrochlorid-monohydrat

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2541924A (en) * 1948-09-17 1951-02-13 Lilly Co Eli Synthesis of substituted imidazoles
AU518569B2 (en) * 1979-08-07 1981-10-08 Farmos-Yhtyma Oy 4-benzyl- and 4-benzoyl imidazole derivatives
GB2092569B (en) * 1981-02-05 1984-09-19 Farmos Oy Substituted imidazole derivatives and their preparation and use

Also Published As

Publication number Publication date
US4584383A (en) 1986-04-22
NO159167B (no) 1988-08-29
ZA848112B (en) 1985-06-26
DK471384D0 (da) 1984-10-02
NZ209896A (en) 1987-02-20
DD236730A1 (de) 1986-06-18
HUT35649A (en) 1985-07-29
HU191960B (en) 1987-04-28
IE57591B1 (en) 1993-01-13
DK174201B1 (da) 2002-09-16
UA5972A1 (uk) 1994-12-29
AU3426384A (en) 1985-04-26
EP0146228A1 (de) 1985-06-26
NO844139L (no) 1985-04-19
EP0146228B1 (de) 1988-01-20
NO159167C (no) 1988-12-07
IE842652L (en) 1985-04-18
IL73255A (en) 1988-11-30
AU566437B2 (en) 1987-10-22
SU1301313A3 (ru) 1987-03-30
DE3468869D1 (en) 1988-02-25
ES8507507A1 (es) 1985-09-01
JPS60149568A (ja) 1985-08-07
DK471384A (da) 1985-04-19
ES536186A0 (es) 1985-09-01
IL73255A0 (en) 1985-01-31
ATE32064T1 (de) 1988-02-15

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Legal Events

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Owner name: FARMOS-YHTYMAE OY