IL71832A0 - New indole compounds - Google Patents
New indole compoundsInfo
- Publication number
- IL71832A0 IL71832A0 IL71832A IL7183284A IL71832A0 IL 71832 A0 IL71832 A0 IL 71832A0 IL 71832 A IL71832 A IL 71832A IL 7183284 A IL7183284 A IL 7183284A IL 71832 A0 IL71832 A0 IL 71832A0
- Authority
- IL
- Israel
- Prior art keywords
- indole compounds
- new indole
- new
- compounds
- indole
- Prior art date
Links
- 150000002475 indoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/76—Nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/495,370 US4536505A (en) | 1983-05-17 | 1983-05-17 | Certain N-(pyridyl) indoles |
Publications (1)
Publication Number | Publication Date |
---|---|
IL71832A0 true IL71832A0 (en) | 1984-09-30 |
Family
ID=23968377
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL71832A IL71832A0 (en) | 1983-05-17 | 1984-05-15 | New indole compounds |
Country Status (15)
Country | Link |
---|---|
US (1) | US4536505A (xx) |
EP (1) | EP0126401A1 (xx) |
JP (1) | JPS59212489A (xx) |
KR (1) | KR840009302A (xx) |
AU (1) | AU2809484A (xx) |
DD (1) | DD224588A5 (xx) |
DK (1) | DK242484A (xx) |
ES (5) | ES8602652A1 (xx) |
FI (1) | FI841925A (xx) |
GR (1) | GR79934B (xx) |
HU (1) | HUT34182A (xx) |
IL (1) | IL71832A0 (xx) |
NO (1) | NO841958L (xx) |
PT (1) | PT78582A (xx) |
ZA (1) | ZA843677B (xx) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4675332A (en) * | 1984-12-10 | 1987-06-23 | Warner-Lambert Company | Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents |
US4609733A (en) * | 1984-12-27 | 1986-09-02 | Ciba-Geigy Corporation | 3-keto-substituted-N-pyridylindoles |
US4758586A (en) * | 1985-02-01 | 1988-07-19 | Usv Pharmaceutical Corp. | Indolyl compounds and hyposensitivity use thereof |
US4970218A (en) * | 1987-04-24 | 1990-11-13 | Hoechst-Roussel Pharmaceuticals Inc. | N-(pyridinyl)-1H-indol-1-amines |
US5039811A (en) * | 1987-04-24 | 1991-08-13 | Hoechst-Roussel Pharmaceuticals Inc. | Preparation of N-(pyridinyl)-1H-indol-1-amines |
US4880822A (en) * | 1987-04-24 | 1989-11-14 | Hoechst-Roussel Pharmaceuticals, Inc. | N-(pyridinyl)-1H-indol-1-amines |
US5550118A (en) * | 1994-01-31 | 1996-08-27 | Eli Lilly And Company | Polyhydronorharman synthase inhibitors |
US5977125A (en) * | 1994-10-31 | 1999-11-02 | Eisai Co., Ltd. | Mono-or polyenic carboxylic acid derivatives |
GB2295151B (en) * | 1994-11-18 | 1998-12-09 | Nmc | Polymerization of substituted heterocyclic monomers |
MXPA00008216A (es) * | 1998-02-23 | 2004-11-22 | Univ South Alabama | Acidos indol-3-propionicos, sales y esteres de los mismos utilizados como medicamentos. |
CA2461360A1 (en) * | 2001-09-26 | 2003-04-03 | Bayer Pharmaceuticals Corporation | 3-pyridyl or 4-isoquinolinyl thiazoles as c17,20 lyase inhibitors |
CN101304976A (zh) * | 2005-10-11 | 2008-11-12 | 因特蒙公司 | 病毒复制抑制剂 |
KR100807718B1 (ko) * | 2006-10-17 | 2008-02-28 | 한국생명공학연구원 | 인돌 유도체를 유효성분으로 함유하는 대사성 질환 예방 및치료용 약학적 조성물 |
MX2009008439A (es) * | 2007-02-12 | 2009-08-13 | Intermune Inc | Nuevos inhibidores de la replicacion del virus de hepatitis c. |
BRPI0809542A8 (pt) * | 2007-03-29 | 2015-09-15 | Asubio Pharma Co Ltd | Compostos derivados de indol tendo atividade de inibição de cpla2, composição farmacêutica, e métodos de produção dos referidos compostos |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3449348A (en) * | 1968-01-08 | 1969-06-10 | Merck & Co Inc | Alpha-halomethyl-1-pyridine or quinoline carbonyl-3-indolylacetic acids |
AT299938B (de) * | 1971-02-03 | 1972-07-10 | Italiana Sint Spa | Verfahren zur Herstellung des neuen Natriumsalzes der (1-Nicotinoyl-2-methyl-5-methoxy-3-indolyl)-essigsäure, gegebenenfalls im Gemisch mit der freien Säure |
FR2171936B1 (xx) * | 1972-02-16 | 1975-04-25 | Clin Midy | |
FR2171937A1 (en) * | 1972-02-16 | 1973-09-28 | Clin Midy | Aminoketo indoles - analgesics and antidepressants |
AT323154B (de) * | 1973-02-02 | 1975-06-25 | Hurka Wilhelm | Verfahren zur herstellung von neuen 5-methoxy-2-methylindol-3-essigsäurederivaten sowie von deren salzen |
DE2862340D1 (en) * | 1978-02-01 | 1983-11-24 | Wellcome Found | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof |
US4322533A (en) * | 1980-03-17 | 1982-03-30 | Lesher George Y | 1H-Indole-2,3-dione derivatives |
US4363912A (en) * | 1980-12-15 | 1982-12-14 | Pfizer Inc. | Indole thromboxane synthetase inhibitors |
CS229934B2 (en) * | 1981-07-07 | 1984-07-16 | Pfizer | Production method subst.indolylacryte acid derivative |
GB2102795A (en) * | 1981-07-31 | 1983-02-09 | Pfizer Ltd | Indole derivatives |
US4478842A (en) * | 1981-11-19 | 1984-10-23 | Ciba-Geigy Corporation | N-Substituted-2-pyridylindoles |
US4460777A (en) * | 1981-11-19 | 1984-07-17 | Ciba-Geigy Corporation | N-Substituted-2-pyridylindoles |
US4511573A (en) * | 1983-05-17 | 1985-04-16 | Ciba-Geigy Corporation | 3-Substituted-2-(heteroaryl) indoles |
-
1983
- 1983-05-17 US US06/495,370 patent/US4536505A/en not_active Expired - Fee Related
-
1984
- 1984-05-14 EP EP84105449A patent/EP0126401A1/de not_active Ceased
- 1984-05-14 FI FI841925A patent/FI841925A/fi not_active Application Discontinuation
- 1984-05-15 JP JP59095771A patent/JPS59212489A/ja active Pending
- 1984-05-15 IL IL71832A patent/IL71832A0/xx unknown
- 1984-05-15 GR GR74706A patent/GR79934B/el unknown
- 1984-05-15 PT PT78582A patent/PT78582A/pt unknown
- 1984-05-16 KR KR1019840002658A patent/KR840009302A/ko not_active Application Discontinuation
- 1984-05-16 HU HU841893A patent/HUT34182A/hu unknown
- 1984-05-16 ZA ZA843677A patent/ZA843677B/xx unknown
- 1984-05-16 NO NO841958A patent/NO841958L/no unknown
- 1984-05-16 DD DD84263081A patent/DD224588A5/de unknown
- 1984-05-16 DK DK242484A patent/DK242484A/da not_active Application Discontinuation
- 1984-05-16 AU AU28094/84A patent/AU2809484A/en not_active Abandoned
- 1984-05-17 ES ES532572A patent/ES8602652A1/es not_active Expired
-
1985
- 1985-07-12 ES ES545151A patent/ES8604195A1/es not_active Expired
- 1985-07-12 ES ES545153A patent/ES8604197A1/es not_active Expired
- 1985-07-12 ES ES545152A patent/ES8604196A1/es not_active Expired
- 1985-07-12 ES ES545154A patent/ES8604922A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
EP0126401A1 (de) | 1984-11-28 |
PT78582A (en) | 1984-06-01 |
KR840009302A (ko) | 1984-12-26 |
US4536505A (en) | 1985-08-20 |
FI841925A0 (fi) | 1984-05-14 |
DK242484A (da) | 1984-11-18 |
ES545154A0 (es) | 1986-02-16 |
ES8604195A1 (es) | 1986-01-16 |
ES545152A0 (es) | 1986-01-16 |
AU2809484A (en) | 1984-11-22 |
ES8604922A1 (es) | 1986-02-16 |
DK242484D0 (da) | 1984-05-16 |
ES532572A0 (es) | 1985-12-01 |
ES8604196A1 (es) | 1986-01-16 |
ZA843677B (en) | 1985-02-27 |
FI841925A (fi) | 1984-11-18 |
GR79934B (xx) | 1984-10-31 |
DD224588A5 (de) | 1985-07-10 |
NO841958L (no) | 1984-11-19 |
ES545153A0 (es) | 1986-01-16 |
ES8602652A1 (es) | 1985-12-01 |
JPS59212489A (ja) | 1984-12-01 |
ES545151A0 (es) | 1986-01-16 |
ES8604197A1 (es) | 1986-01-16 |
HUT34182A (en) | 1985-02-28 |
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