ES545151A0 - Procedimiento para la preparacion de n-piridilindoles - Google Patents

Procedimiento para la preparacion de n-piridilindoles

Info

Publication number
ES545151A0
ES545151A0 ES545151A ES545151A ES545151A0 ES 545151 A0 ES545151 A0 ES 545151A0 ES 545151 A ES545151 A ES 545151A ES 545151 A ES545151 A ES 545151A ES 545151 A0 ES545151 A0 ES 545151A0
Authority
ES
Spain
Prior art keywords
piridylindols
procedure
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES545151A
Other languages
English (en)
Other versions
ES8604195A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES545151A0 publication Critical patent/ES545151A0/es
Publication of ES8604195A1 publication Critical patent/ES8604195A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/76—Nitrogen atoms to which a second hetero atom is attached
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
ES545151A 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles Expired ES8604195A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/495,370 US4536505A (en) 1983-05-17 1983-05-17 Certain N-(pyridyl) indoles

Publications (2)

Publication Number Publication Date
ES545151A0 true ES545151A0 (es) 1986-01-16
ES8604195A1 ES8604195A1 (es) 1986-01-16

Family

ID=23968377

Family Applications (5)

Application Number Title Priority Date Filing Date
ES532572A Expired ES8602652A1 (es) 1983-05-17 1984-05-17 Procedimiento para la preparacion de n-piridilindoles
ES545153A Expired ES8604197A1 (es) 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles
ES545152A Expired ES8604196A1 (es) 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles
ES545154A Expired ES8604922A1 (es) 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles
ES545151A Expired ES8604195A1 (es) 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles

Family Applications Before (4)

Application Number Title Priority Date Filing Date
ES532572A Expired ES8602652A1 (es) 1983-05-17 1984-05-17 Procedimiento para la preparacion de n-piridilindoles
ES545153A Expired ES8604197A1 (es) 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles
ES545152A Expired ES8604196A1 (es) 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles
ES545154A Expired ES8604922A1 (es) 1983-05-17 1985-07-12 Procedimiento para la preparacion de n-piridilindoles

Country Status (15)

Country Link
US (1) US4536505A (es)
EP (1) EP0126401A1 (es)
JP (1) JPS59212489A (es)
KR (1) KR840009302A (es)
AU (1) AU2809484A (es)
DD (1) DD224588A5 (es)
DK (1) DK242484A (es)
ES (5) ES8602652A1 (es)
FI (1) FI841925A7 (es)
GR (1) GR79934B (es)
HU (1) HUT34182A (es)
IL (1) IL71832A0 (es)
NO (1) NO841958L (es)
PT (1) PT78582A (es)
ZA (1) ZA843677B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675332A (en) * 1984-12-10 1987-06-23 Warner-Lambert Company Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
US4758586A (en) * 1985-02-01 1988-07-19 Usv Pharmaceutical Corp. Indolyl compounds and hyposensitivity use thereof
US4880822A (en) * 1987-04-24 1989-11-14 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyridinyl)-1H-indol-1-amines
US4970218A (en) * 1987-04-24 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. N-(pyridinyl)-1H-indol-1-amines
US5039811A (en) * 1987-04-24 1991-08-13 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-(pyridinyl)-1H-indol-1-amines
US5550118A (en) * 1994-01-31 1996-08-27 Eli Lilly And Company Polyhydronorharman synthase inhibitors
US5977125A (en) * 1994-10-31 1999-11-02 Eisai Co., Ltd. Mono-or polyenic carboxylic acid derivatives
GB2295151B (en) * 1994-11-18 1998-12-09 Nmc Polymerization of substituted heterocyclic monomers
IL137848A0 (en) * 1998-02-23 2001-10-31 Univ South Alabama Indole-3-propionic acids, salts and esters thereof used as medicaments
JP2005532983A (ja) * 2001-09-26 2005-11-04 バイエル・フアーマシユーチカルズ・コーポレーシヨン Ｃ１７，２０リアーゼ阻害剤としての３‐ピリジルもしくは４‐イソキノリニルチアゾール
EP1943228A2 (en) * 2005-10-11 2008-07-16 Intermune, Inc. Inhibitors of viral replication
KR100807718B1 (ko) * 2006-10-17 2008-02-28 한국생명공학연구원 인돌 유도체를 유효성분으로 함유하는 대사성 질환 예방 및치료용 약학적 조성물
MX2009008439A (es) * 2007-02-12 2009-08-13 Intermune Inc Nuevos inhibidores de la replicacion del virus de hepatitis c.
BRPI0809542A8 (pt) * 2007-03-29 2015-09-15 Asubio Pharma Co Ltd Compostos derivados de indol tendo atividade de inibição de cpla2, composição farmacêutica, e métodos de produção dos referidos compostos
USD1099827S1 (en) * 2023-06-05 2025-10-28 Apple Inc. Cable

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449348A (en) * 1968-01-08 1969-06-10 Merck & Co Inc Alpha-halomethyl-1-pyridine or quinoline carbonyl-3-indolylacetic acids
AT299938B (de) * 1971-02-03 1972-07-10 Italiana Sint Spa Verfahren zur Herstellung des neuen Natriumsalzes der (1-Nicotinoyl-2-methyl-5-methoxy-3-indolyl)-essigsäure, gegebenenfalls im Gemisch mit der freien Säure
FR2171937A1 (en) * 1972-02-16 1973-09-28 Clin Midy Aminoketo indoles - analgesics and antidepressants
FR2171936B1 (es) * 1972-02-16 1975-04-25 Clin Midy
AT323154B (de) * 1973-02-02 1975-06-25 Hurka Wilhelm Verfahren zur herstellung von neuen 5-methoxy-2-methylindol-3-essigsäurederivaten sowie von deren salzen
DE2862340D1 (en) * 1978-02-01 1983-11-24 Wellcome Found Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
US4322533A (en) * 1980-03-17 1982-03-30 Lesher George Y 1H-Indole-2,3-dione derivatives
US4363912A (en) * 1980-12-15 1982-12-14 Pfizer Inc. Indole thromboxane synthetase inhibitors
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
GB2102795A (en) * 1981-07-31 1983-02-09 Pfizer Ltd Indole derivatives
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles

Also Published As

Publication number Publication date
AU2809484A (en) 1984-11-22
DD224588A5 (de) 1985-07-10
ZA843677B (en) 1985-02-27
HUT34182A (en) 1985-02-28
FI841925A7 (fi) 1984-11-18
ES532572A0 (es) 1985-12-01
ES8604922A1 (es) 1986-02-16
GR79934B (es) 1984-10-31
FI841925A0 (fi) 1984-05-14
PT78582A (en) 1984-06-01
ES8604196A1 (es) 1986-01-16
ES8602652A1 (es) 1985-12-01
ES545153A0 (es) 1986-01-16
ES8604197A1 (es) 1986-01-16
ES545152A0 (es) 1986-01-16
EP0126401A1 (de) 1984-11-28
JPS59212489A (ja) 1984-12-01
NO841958L (no) 1984-11-19
KR840009302A (ko) 1984-12-26
DK242484A (da) 1984-11-18
ES545154A0 (es) 1986-02-16
ES8604195A1 (es) 1986-01-16
US4536505A (en) 1985-08-20
DK242484D0 (da) 1984-05-16
IL71832A0 (en) 1984-09-30

Similar Documents

Publication Publication Date Title
ES533260A0 (es) Procedimiento para la preparacion de 13a-alquilgonanos
ES532183A0 (es) Procedimiento para la preparacion de compuestos cefemicos
ES544286A0 (es) Procedimiento para la preparacion de nuevos derivados tiazo-lidinicos
ES537502A0 (es) Procedimiento para la preparacion de imidazolinonas
ES538621A0 (es) Procedimiento para la preparacion de fenolsulfonftaleinil-b-d-galactosidos
ES532572A0 (es) Procedimiento para la preparacion de n-piridilindoles
MX159669A (es) Procedimiento para la preparacion de derivados de acilamida
MX156242A (es) Procedimiento para la preparacion de eter-sulfonatos
ES532957A0 (es) Procedimiento para la preparacion de sulfonilureas substituidas
ES533497A0 (es) Procedimiento para la preparacion de nuevos derivados de 3-fenil-4-cianopirrol
ES537829A0 (es) Procedimiento para la obtencion de compuestos de eglina
ES535326A0 (es) Procedimiento para la preparacion de nuevos eteres tetraglioidilicos
ES535185A0 (es) Procedimiento para la preparacion de nuevas oxadiacinas
ES528114A0 (es) Procedimiento para la preparacion de hexanorbrassinolid-22-eteres
ES535373A0 (es) Procedimiento para la preparacion de nuevas pirazolil- e isoxazolilsulfonilureas
ES523990A0 (es) Procedimiento para la preparacion de furobenzoisoxazoles.
AR229374A1 (es) Procedimiento para la preparacion de 2-hidroximetil-3-hidroxi-6-(1-hidroxi-2-t-butilaminoetil)-piridina
ES527552A0 (es) Procedimiento para la preparacion de acridanona
ES531024A0 (es) Procedimiento para la preparacion de aminonitrilos
MX162546A (es) Procedimiento mejorado para la preparacion de 2-halogenoresorcinoles
ES523098A0 (es) Procedimiento para la preparacion de compuestos de 4-azaftalida
MX159538A (es) Procedimiento para la preparacion de 3-acil-2-nitrometilen-tetrahidro-2h-1,3-tiazina
AR240793A1 (es) Procedimiento para la preparacion de benzantrona
ES524727A0 (es) Procedimiento para la preparacion de n-acetil-4-triazolidincarboxilato de guayacol
ES536489A0 (es) Procedimiento para la preparacion de e-triazolil-pentenoles