GR79934B - - Google Patents

Info

Publication number
GR79934B
GR79934B GR74706A GR840174706A GR79934B GR 79934 B GR79934 B GR 79934B GR 74706 A GR74706 A GR 74706A GR 840174706 A GR840174706 A GR 840174706A GR 79934 B GR79934 B GR 79934B
Authority
GR
Greece
Application number
GR74706A
Original Assignee
Ciba Geigy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy filed Critical Ciba Geigy
Publication of GR79934B publication Critical patent/GR79934B/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/76Nitrogen atoms to which a second hetero atom is attached
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
GR74706A 1983-05-17 1984-05-15 GR79934B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/495,370 US4536505A (en) 1983-05-17 1983-05-17 Certain N-(pyridyl) indoles

Publications (1)

Publication Number Publication Date
GR79934B true GR79934B (el) 1984-10-31

Family

ID=23968377

Family Applications (1)

Application Number Title Priority Date Filing Date
GR74706A GR79934B (el) 1983-05-17 1984-05-15

Country Status (15)

Country Link
US (1) US4536505A (el)
EP (1) EP0126401A1 (el)
JP (1) JPS59212489A (el)
KR (1) KR840009302A (el)
AU (1) AU2809484A (el)
DD (1) DD224588A5 (el)
DK (1) DK242484A (el)
ES (5) ES8602652A1 (el)
FI (1) FI841925A (el)
GR (1) GR79934B (el)
HU (1) HUT34182A (el)
IL (1) IL71832A0 (el)
NO (1) NO841958L (el)
PT (1) PT78582A (el)
ZA (1) ZA843677B (el)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675332A (en) * 1984-12-10 1987-06-23 Warner-Lambert Company Acidic tetrazolyl substituted indole compounds and their use as antiallergy agents
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
US4758586A (en) * 1985-02-01 1988-07-19 Usv Pharmaceutical Corp. Indolyl compounds and hyposensitivity use thereof
US4880822A (en) * 1987-04-24 1989-11-14 Hoechst-Roussel Pharmaceuticals, Inc. N-(pyridinyl)-1H-indol-1-amines
US4970218A (en) * 1987-04-24 1990-11-13 Hoechst-Roussel Pharmaceuticals Inc. N-(pyridinyl)-1H-indol-1-amines
US5039811A (en) * 1987-04-24 1991-08-13 Hoechst-Roussel Pharmaceuticals Inc. Preparation of N-(pyridinyl)-1H-indol-1-amines
US5550118A (en) * 1994-01-31 1996-08-27 Eli Lilly And Company Polyhydronorharman synthase inhibitors
US5977125A (en) * 1994-10-31 1999-11-02 Eisai Co., Ltd. Mono-or polyenic carboxylic acid derivatives
GB2295151B (en) * 1994-11-18 1998-12-09 Nmc Polymerization of substituted heterocyclic monomers
BR9908165A (pt) * 1998-02-23 2000-10-31 Univ South Alabama Processos de prevenção de um citotóxico de proteìna beta amilóide em células, de tratamento de uma fibrilogênica em um sujeito humano, de diminuição da oxidação em uma amostra biológica e de tratamento de doenças ou outros quadros em que radicais livres e/ou tensão oxidativa desempenham um papel, e, uso de ácido indol-3-propiÈnico ou um seu sal ou éster.
WO2003027107A1 (en) * 2001-09-26 2003-04-03 Bayer Pharmaceuticals Corporation Substituted 3-pyridyl oxazoles as c17,20 lyase inhibitors
BRPI0617271A2 (pt) * 2005-10-11 2011-07-19 Intermune Inc inibidores de replicação viral
KR100807718B1 (ko) * 2006-10-17 2008-02-28 한국생명공학연구원 인돌 유도체를 유효성분으로 함유하는 대사성 질환 예방 및치료용 약학적 조성물
US20090047246A1 (en) * 2007-02-12 2009-02-19 Intermune, Inc. Novel inhibitors of hepatitis c virus replication
US8293781B2 (en) * 2007-03-29 2012-10-23 Daiichi Sankyo Company, Limited Indole derivatives having cPLA2 inhibiting activity and applications and production methods of the same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3449348A (en) * 1968-01-08 1969-06-10 Merck & Co Inc Alpha-halomethyl-1-pyridine or quinoline carbonyl-3-indolylacetic acids
AT299938B (de) * 1971-02-03 1972-07-10 Italiana Sint Spa Verfahren zur Herstellung des neuen Natriumsalzes der (1-Nicotinoyl-2-methyl-5-methoxy-3-indolyl)-essigsäure, gegebenenfalls im Gemisch mit der freien Säure
FR2171936B1 (el) * 1972-02-16 1975-04-25 Clin Midy
FR2171937A1 (en) * 1972-02-16 1973-09-28 Clin Midy Aminoketo indoles - analgesics and antidepressants
AT323154B (de) * 1973-02-02 1975-06-25 Hurka Wilhelm Verfahren zur herstellung von neuen 5-methoxy-2-methylindol-3-essigsäurederivaten sowie von deren salzen
DE2862340D1 (en) * 1978-02-01 1983-11-24 Wellcome Found Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations thereof
US4322533A (en) * 1980-03-17 1982-03-30 Lesher George Y 1H-Indole-2,3-dione derivatives
US4363912A (en) * 1980-12-15 1982-12-14 Pfizer Inc. Indole thromboxane synthetase inhibitors
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
GB2102795A (en) * 1981-07-31 1983-02-09 Pfizer Ltd Indole derivatives
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles

Also Published As

Publication number Publication date
IL71832A0 (en) 1984-09-30
US4536505A (en) 1985-08-20
ES532572A0 (es) 1985-12-01
JPS59212489A (ja) 1984-12-01
FI841925A0 (fi) 1984-05-14
ES8604196A1 (es) 1986-01-16
PT78582A (en) 1984-06-01
NO841958L (no) 1984-11-19
DK242484D0 (da) 1984-05-16
ES8604922A1 (es) 1986-02-16
KR840009302A (ko) 1984-12-26
ES545153A0 (es) 1986-01-16
ZA843677B (en) 1985-02-27
DK242484A (da) 1984-11-18
ES545154A0 (es) 1986-02-16
AU2809484A (en) 1984-11-22
ES8604195A1 (es) 1986-01-16
ES8602652A1 (es) 1985-12-01
EP0126401A1 (de) 1984-11-28
ES545151A0 (es) 1986-01-16
ES8604197A1 (es) 1986-01-16
DD224588A5 (de) 1985-07-10
ES545152A0 (es) 1986-01-16
HUT34182A (en) 1985-02-28
FI841925A (fi) 1984-11-18

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