IL70414A - Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors - Google Patents
Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectorsInfo
- Publication number
- IL70414A IL70414A IL70414A IL7041483A IL70414A IL 70414 A IL70414 A IL 70414A IL 70414 A IL70414 A IL 70414A IL 7041483 A IL7041483 A IL 7041483A IL 70414 A IL70414 A IL 70414A
- Authority
- IL
- Israel
- Prior art keywords
- dna fragments
- polypeptide
- vectors
- human
- preparing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/64—Relaxins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- General Engineering & Computer Science (AREA)
- Reproductive Health (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPF724782 | 1982-12-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL70414A0 IL70414A0 (en) | 1984-03-30 |
IL70414A true IL70414A (en) | 1991-06-10 |
Family
ID=3769889
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL70414A IL70414A (en) | 1982-12-13 | 1983-12-09 | Polypeptide having human h2-relaxin activity,double-stranded dna fragments coding therefor,vectors containing the dna fragments and methods for preparing the polypeptide,dna fragments and vectors |
Country Status (14)
Country | Link |
---|---|
US (1) | US4758516A (de) |
EP (2) | EP0303033B1 (de) |
JP (3) | JP2545055B2 (de) |
KR (1) | KR940002536B1 (de) |
AT (2) | ATE62507T1 (de) |
CA (1) | CA1220735A (de) |
DE (1) | DE3382249D1 (de) |
DK (2) | DK171684B1 (de) |
ES (6) | ES8602133A1 (de) |
HU (1) | HU197767B (de) |
IE (1) | IE63902B1 (de) |
IL (1) | IL70414A (de) |
NZ (1) | NZ206534A (de) |
ZA (1) | ZA839231B (de) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE78042T1 (de) * | 1982-08-12 | 1992-07-15 | Florey Howard Inst | Analoge des humanen relaxins. |
US5179195A (en) * | 1982-12-13 | 1993-01-12 | Howard Florey Institute Of Experimental Physiology And Medicine | Human relaxin polypeptides |
US4835251A (en) * | 1986-06-23 | 1989-05-30 | Genetech, Inc. | Method of chain combination |
AU612594B2 (en) * | 1986-09-12 | 1991-07-18 | Genentech Inc. | Human prorelaxin |
AU626840B2 (en) * | 1988-02-26 | 1992-08-13 | Genentech Inc. | Human relaxin formulation |
CA2051375C (en) * | 1989-05-04 | 2000-09-12 | Dennis J. Henner | Process and compositions for the isolation of human relaxin |
US5089419A (en) * | 1989-08-07 | 1992-02-18 | International Canine Genetics | Detection of pregnancy by identification of the c peptide of relaxin in the urine of animals |
US5478807A (en) * | 1991-08-19 | 1995-12-26 | Genentech, Inc. | Use of relaxin in the treatment of bradycardia |
US5166191A (en) * | 1991-08-19 | 1992-11-24 | Genentech, Inc. | Use of relaxin in cardiovascular therapy |
JPH07508341A (ja) * | 1991-10-28 | 1995-09-14 | ボード・オヴ・リージェンツ,ザ・ユニヴァーシティ・オヴ・テキサス・システム | 生物サンプルおよび体液中の正常細胞と悪性腫瘍細胞とにおける分化マーカーの検出方法 |
US6348327B1 (en) | 1991-12-06 | 2002-02-19 | Genentech, Inc. | Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells |
ATE241012T1 (de) * | 1993-06-21 | 2003-06-15 | Genentech Inc | Verfahren zur herstellung von humanen relaxin |
US20050032683A1 (en) * | 2000-10-04 | 2005-02-10 | Amento Edward P. | Methods of modulating apoptosis by administration of relaxin agonists or antagonists |
US20040006205A1 (en) * | 2001-04-03 | 2004-01-08 | Li Li | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
US20030088884A1 (en) * | 2001-08-17 | 2003-05-08 | Hsu Sheau Yu | Mammalian relaxin receptors |
AU2003903124A0 (en) * | 2003-06-20 | 2003-07-10 | Mark Del Borgo | Analogues of heteromeric proteins |
WO2005115435A2 (en) * | 2004-04-30 | 2005-12-08 | Bas Medical, Inc. | Methods and compositions for control of fetal growth via modulation of relaxin |
US20060052304A1 (en) * | 2004-09-02 | 2006-03-09 | Bas Medical, Inc. | Method for remodeling bone and related sutures |
US20110166070A1 (en) * | 2008-05-16 | 2011-07-07 | Stewart Dennis R | Method of preventing premature delivery |
GR1006941B (el) | 2009-06-01 | 2010-08-27 | Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras), | Πεπτιδικη συνθεση (peptide synthesis) |
US8389475B2 (en) * | 2009-08-10 | 2013-03-05 | The Board Of Trustees Of The Leland Stanford Junior University | Relaxin analogs |
WO2012024452A2 (en) * | 2010-08-17 | 2012-02-23 | Ambrx, Inc. | Modified relaxin polypeptides and their uses |
AR087020A1 (es) * | 2011-07-01 | 2014-02-05 | Bayer Ip Gmbh | Polipeptidos de fusion de relaxina y usos de los mismos |
EP2630964A1 (de) | 2012-02-22 | 2013-08-28 | Immundiagnostik AG | Verfahren und Medikation zur Behandlung von Patienten mit Risiko für Prädiabetes und Typ-2-Diabetes |
US20160296632A1 (en) | 2013-11-13 | 2016-10-13 | Aequus Biopharma, Inc. | Engineered glycoproteins and uses thereof |
EP2946788A1 (de) | 2014-05-23 | 2015-11-25 | Immundiagnostik AG | Verfahren und Zusammensetzung zur Behandlung von Herzversagen mit erhaltener Austreibungsfraktion |
KR20230074598A (ko) | 2016-05-18 | 2023-05-30 | 모더나티엑스, 인크. | 릴랙신을 인코딩하는 폴리뉴클레오타이드 |
AU2018219283B2 (en) | 2017-02-08 | 2022-05-19 | Bristol-Myers Squibb Company | Modified relaxin polypeptides comprising a pharmacokinetic enhancer and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4468464A (en) * | 1974-11-04 | 1984-08-28 | The Board Of Trustees Of The Leland Stanford Junior University | Biologically functional molecular chimeras |
GR70279B (de) * | 1979-09-12 | 1982-09-03 | Univ California | |
US4267101A (en) * | 1980-02-01 | 1981-05-12 | Serono Laboratories Inc. | Process for obtaining human relaxin from fetal membranes |
EP0068375A3 (de) * | 1981-06-22 | 1983-04-13 | G.D. Searle & Co. | Rekombinante DNS Technik zur Herstellung von Relaxin |
IE55479B1 (en) * | 1982-02-12 | 1990-09-26 | Florey Howard Inst | Molecular cloning and characterization of the gene sequence coding for porcine relaxin |
ATE78042T1 (de) * | 1982-08-12 | 1992-07-15 | Florey Howard Inst | Analoge des humanen relaxins. |
-
1983
- 1983-12-09 NZ NZ206534A patent/NZ206534A/en unknown
- 1983-12-09 IL IL70414A patent/IL70414A/xx not_active IP Right Cessation
- 1983-12-12 ZA ZA839231A patent/ZA839231B/xx unknown
- 1983-12-12 CA CA000443049A patent/CA1220735A/en not_active Expired
- 1983-12-12 AT AT83307553T patent/ATE62507T1/de not_active IP Right Cessation
- 1983-12-12 ES ES527964A patent/ES8602133A1/es not_active Expired
- 1983-12-12 EP EP88110103A patent/EP0303033B1/de not_active Expired - Lifetime
- 1983-12-12 DE DE8383307553T patent/DE3382249D1/de not_active Expired - Lifetime
- 1983-12-12 AT AT88110103T patent/ATE90360T1/de not_active IP Right Cessation
- 1983-12-12 IE IE290883A patent/IE63902B1/en not_active IP Right Cessation
- 1983-12-12 EP EP83307553A patent/EP0112149B1/de not_active Expired - Lifetime
- 1983-12-13 JP JP58233744A patent/JP2545055B2/ja not_active Expired - Lifetime
- 1983-12-13 HU HU834243A patent/HU197767B/hu unknown
- 1983-12-13 DK DK573783A patent/DK171684B1/da not_active IP Right Cessation
- 1983-12-13 KR KR1019830005905A patent/KR940002536B1/ko not_active IP Right Cessation
- 1983-12-13 US US06/560,790 patent/US4758516A/en not_active Expired - Lifetime
-
1985
- 1985-06-17 ES ES544293A patent/ES8802249A1/es not_active Expired
-
1986
- 1986-02-17 ES ES552095A patent/ES8801373A1/es not_active Expired
- 1986-02-17 ES ES552093A patent/ES8708016A1/es not_active Expired
- 1986-02-17 ES ES552094A patent/ES8708015A1/es not_active Expired
-
1987
- 1987-05-11 ES ES557531A patent/ES8801675A1/es not_active Expired
-
1992
- 1992-11-30 DK DK143492A patent/DK172012B1/da not_active IP Right Cessation
-
1993
- 1993-03-22 JP JP5061747A patent/JP2677332B2/ja not_active Expired - Lifetime
-
1994
- 1994-10-26 JP JP6262254A patent/JP2891882B2/ja not_active Expired - Lifetime
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |