ES544293A0 - Un procedimiento para el aislamiento de un gen de relaxina de un ser humano u otro primate o de una especie relacionada - Google Patents

Un procedimiento para el aislamiento de un gen de relaxina de un ser humano u otro primate o de una especie relacionada

Info

Publication number
ES544293A0
ES544293A0 ES544293A ES544293A ES544293A0 ES 544293 A0 ES544293 A0 ES 544293A0 ES 544293 A ES544293 A ES 544293A ES 544293 A ES544293 A ES 544293A ES 544293 A0 ES544293 A0 ES 544293A0
Authority
ES
Spain
Prior art keywords
human
primate
isolation
procedure
related species
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES544293A
Other languages
English (en)
Other versions
ES8802249A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Florey Institute of Neuroscience and Mental Health
Original Assignee
Howard Florey Institute of Experimental Physiology and Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3769889&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES544293(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Howard Florey Institute of Experimental Physiology and Medicine filed Critical Howard Florey Institute of Experimental Physiology and Medicine
Publication of ES8802249A1 publication Critical patent/ES8802249A1/es
Publication of ES544293A0 publication Critical patent/ES544293A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/64—Relaxins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
ES544293A 1982-12-13 1985-06-17 Un procedimiento para el aislamiento de un gen de relaxina de un ser humano u otro primate o de una especie relacionada Expired ES8802249A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPF724782 1982-12-13

Publications (2)

Publication Number Publication Date
ES8802249A1 ES8802249A1 (es) 1988-04-16
ES544293A0 true ES544293A0 (es) 1988-04-16

Family

ID=3769889

Family Applications (6)

Application Number Title Priority Date Filing Date
ES527964A Granted ES527964A0 (es) 1982-12-13 1983-12-12 Un procedimiento para preparar un vector de transferencias de adn
ES544293A Expired ES8802249A1 (es) 1982-12-13 1985-06-17 Un procedimiento para el aislamiento de un gen de relaxina de un ser humano u otro primate o de una especie relacionada
ES552093A Expired ES8708016A1 (es) 1982-12-13 1986-02-17 Un procedimiento para sintetizar una secuencia de aminoacidos que contienen la totalidad o parte de la secuencia de aminoacidos de la preprorrelaxina -h2 humana.
ES552094A Expired ES8708015A1 (es) 1982-12-13 1986-02-17 Un procedimiento para preparar relaxina -h2 humana o uno de sus analogos
ES552095A Expired ES8801373A1 (es) 1982-12-13 1986-02-17 Un procedimiento para aislar un gen de preprorrelaxina -h2 humana o un equivalente o subunidad del mismo
ES557531A Expired ES8801675A1 (es) 1982-12-13 1987-05-11 Un procedimiento para preparar relaxina-h2 humana

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES527964A Granted ES527964A0 (es) 1982-12-13 1983-12-12 Un procedimiento para preparar un vector de transferencias de adn

Family Applications After (4)

Application Number Title Priority Date Filing Date
ES552093A Expired ES8708016A1 (es) 1982-12-13 1986-02-17 Un procedimiento para sintetizar una secuencia de aminoacidos que contienen la totalidad o parte de la secuencia de aminoacidos de la preprorrelaxina -h2 humana.
ES552094A Expired ES8708015A1 (es) 1982-12-13 1986-02-17 Un procedimiento para preparar relaxina -h2 humana o uno de sus analogos
ES552095A Expired ES8801373A1 (es) 1982-12-13 1986-02-17 Un procedimiento para aislar un gen de preprorrelaxina -h2 humana o un equivalente o subunidad del mismo
ES557531A Expired ES8801675A1 (es) 1982-12-13 1987-05-11 Un procedimiento para preparar relaxina-h2 humana

Country Status (14)

Country Link
US (1) US4758516A (es)
EP (2) EP0303033B1 (es)
JP (3) JP2545055B2 (es)
KR (1) KR940002536B1 (es)
AT (2) ATE62507T1 (es)
CA (1) CA1220735A (es)
DE (1) DE3382249D1 (es)
DK (2) DK171684B1 (es)
ES (6) ES527964A0 (es)
HU (1) HU197767B (es)
IE (1) IE63902B1 (es)
IL (1) IL70414A (es)
NZ (1) NZ206534A (es)
ZA (1) ZA839231B (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3382117D1 (de) * 1982-08-12 1991-02-21 Florey Howard Inst Molekulare klonierung und charakterisierung der das menschliche relaxin kodierenden gen-sequenz.
US5179195A (en) * 1982-12-13 1993-01-12 Howard Florey Institute Of Experimental Physiology And Medicine Human relaxin polypeptides
US4835251A (en) * 1986-06-23 1989-05-30 Genetech, Inc. Method of chain combination
EP0260149A1 (en) * 1986-09-12 1988-03-16 Howard Florey Institute Of Experimental Physiology And Medicine Human prorelaxin for therapeutic use
AU626840B2 (en) * 1988-02-26 1992-08-13 Genentech Inc. Human relaxin formulation
DE69001248T2 (de) * 1989-05-04 1993-10-14 Genentech Inc Verfahren und zusammensetzungen zur isolation von menschlichem relaxin.
US5089419A (en) * 1989-08-07 1992-02-18 International Canine Genetics Detection of pregnancy by identification of the c peptide of relaxin in the urine of animals
US5166191A (en) * 1991-08-19 1992-11-24 Genentech, Inc. Use of relaxin in cardiovascular therapy
US5478807A (en) * 1991-08-19 1995-12-26 Genentech, Inc. Use of relaxin in the treatment of bradycardia
CA2121683A1 (en) * 1991-10-28 1993-05-13 Reuben Lotan A method for detecting a differentiation marker in normal and carcinoma cells and in biological samples and body fluid
US6348327B1 (en) 1991-12-06 2002-02-19 Genentech, Inc. Non-endocrine animal host cells capable of expressing variant proinsulin and processing the same to form active, mature insulin and methods of culturing such cells
AU691189B2 (en) * 1993-06-21 1998-05-14 Genentech Inc. Process for producing relaxin
US20050032683A1 (en) 2000-10-04 2005-02-10 Amento Edward P. Methods of modulating apoptosis by administration of relaxin agonists or antagonists
US20040006205A1 (en) * 2001-04-03 2004-01-08 Li Li Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US20030088884A1 (en) * 2001-08-17 2003-05-08 Hsu Sheau Yu Mammalian relaxin receptors
AU2003903124A0 (en) * 2003-06-20 2003-07-10 Mark Del Borgo Analogues of heteromeric proteins
EP1753449A4 (en) * 2004-04-30 2009-09-23 Corthera Inc METHOD AND COMPOSITIONS FOR CONTROLLING FEDERAL GROWTH BY RELAXIN MODULATION
US20060052304A1 (en) * 2004-09-02 2006-03-09 Bas Medical, Inc. Method for remodeling bone and related sutures
PT2288367E (pt) * 2008-05-16 2016-02-09 Corthera Inc Relaxina h2 para utilização no tratamento da dilatação cervical prematura
GR1006941B (el) 2009-06-01 2010-08-27 Χημικα Και Βιοφαρμακευτικα Εργαστηρια Πατρων Αε (Cbl-Patras), Πεπτιδικη συνθεση (peptide synthesis)
US8389475B2 (en) 2009-08-10 2013-03-05 The Board Of Trustees Of The Leland Stanford Junior University Relaxin analogs
EP2605789B1 (en) 2010-08-17 2019-06-05 Ambrx, Inc. Modified relaxin polypeptides and their uses
AU2012280474A1 (en) * 2011-07-01 2014-01-16 Bayer Intellectual Property Gmbh Relaxin fusion polypeptides and uses thereof
EP2630964A1 (en) 2012-02-22 2013-08-28 Immundiagnostik AG Method and medicament for treating patients in risk of prediabetes and type-2 diabetes
US20160296632A1 (en) 2013-11-13 2016-10-13 Aequus Biopharma, Inc. Engineered glycoproteins and uses thereof
EP2946788A1 (en) 2014-05-23 2015-11-25 Immundiagnostik AG Method and composition for treating heart failure with preserved ejection fraction
SG11201810256XA (en) 2016-05-18 2018-12-28 Modernatx Inc Polynucleotides encoding relaxin
MX2019008449A (es) 2017-02-08 2019-09-09 Bristol Myers Squibb Co Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4468464A (en) * 1974-11-04 1984-08-28 The Board Of Trustees Of The Leland Stanford Junior University Biologically functional molecular chimeras
GR70279B (es) * 1979-09-12 1982-09-03 Univ California
US4267101A (en) * 1980-02-01 1981-05-12 Serono Laboratories Inc. Process for obtaining human relaxin from fetal membranes
EP0068375A3 (en) * 1981-06-22 1983-04-13 G.D. Searle & Co. Recombinant dna techniques for the production of relaxin
IE55479B1 (en) * 1982-02-12 1990-09-26 Florey Howard Inst Molecular cloning and characterization of the gene sequence coding for porcine relaxin
DE3382117D1 (de) * 1982-08-12 1991-02-21 Florey Howard Inst Molekulare klonierung und charakterisierung der das menschliche relaxin kodierenden gen-sequenz.

Also Published As

Publication number Publication date
DK573783D0 (da) 1983-12-13
KR840007024A (ko) 1984-12-04
ZA839231B (en) 1984-08-29
ES8801373A1 (es) 1987-12-16
KR940002536B1 (ko) 1994-03-25
ATE62507T1 (de) 1991-04-15
ES552094A0 (es) 1987-09-01
JPH06100585A (ja) 1994-04-12
DK172012B1 (da) 1997-09-15
IL70414A0 (en) 1984-03-30
JP2545055B2 (ja) 1996-10-16
IL70414A (en) 1991-06-10
ES8602133A1 (es) 1985-11-16
US4758516A (en) 1988-07-19
NZ206534A (en) 1988-05-30
ES552093A0 (es) 1987-09-01
ES8708015A1 (es) 1987-09-01
ES8802249A1 (es) 1988-04-16
EP0303033A3 (en) 1989-10-25
ES8801675A1 (es) 1988-02-16
DK143492A (da) 1992-11-30
EP0303033B1 (en) 1993-06-09
EP0303033A2 (en) 1989-02-15
EP0112149B1 (en) 1991-04-10
JPH07173198A (ja) 1995-07-11
EP0112149A2 (en) 1984-06-27
ATE90360T1 (de) 1993-06-15
DK171684B1 (da) 1997-03-10
CA1220735A (en) 1987-04-21
ES557531A0 (es) 1988-02-16
ES8708016A1 (es) 1987-09-01
EP0112149A3 (en) 1985-05-22
JP2677332B2 (ja) 1997-11-17
JP2891882B2 (ja) 1999-05-17
DK573783A (da) 1984-06-14
DK143492D0 (da) 1992-11-30
ES527964A0 (es) 1985-11-16
IE832908L (en) 1984-06-13
JPS59156284A (ja) 1984-09-05
HU197767B (en) 1989-05-29
IE63902B1 (en) 1995-06-14
DE3382249D1 (de) 1991-05-16
ES552095A0 (es) 1987-12-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19991007