IL70071A - Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient - Google Patents

Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient

Info

Publication number
IL70071A
IL70071A IL70071A IL7007183A IL70071A IL 70071 A IL70071 A IL 70071A IL 70071 A IL70071 A IL 70071A IL 7007183 A IL7007183 A IL 7007183A IL 70071 A IL70071 A IL 70071A
Authority
IL
Israel
Prior art keywords
active ingredient
sustained release
uniform distribution
release pharmaceutical
pharmaceutical tablets
Prior art date
Application number
IL70071A
Other languages
English (en)
Other versions
IL70071A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL70071A0 publication Critical patent/IL70071A0/xx
Publication of IL70071A publication Critical patent/IL70071A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
IL70071A 1982-11-01 1983-10-27 Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient IL70071A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US43810082A 1982-11-01 1982-11-01
US53612883A 1983-09-27 1983-09-27

Publications (2)

Publication Number Publication Date
IL70071A0 IL70071A0 (en) 1984-01-31
IL70071A true IL70071A (en) 1987-12-31

Family

ID=27031546

Family Applications (1)

Application Number Title Priority Date Filing Date
IL70071A IL70071A (en) 1982-11-01 1983-10-27 Multilayered sustained release pharmaceutical tablets having non-uniform distribution of active ingredient

Country Status (13)

Country Link
EP (1) EP0111144B1 (xx)
KR (1) KR900007311B1 (xx)
AU (1) AU554377B2 (xx)
CA (1) CA1220137A (xx)
DE (1) DE3368011D1 (xx)
DK (1) DK499183A (xx)
ES (1) ES8607008A1 (xx)
GR (1) GR78740B (xx)
IE (1) IE56182B1 (xx)
IL (1) IL70071A (xx)
NO (1) NO163356C (xx)
NZ (1) NZ206094A (xx)
PH (1) PH20332A (xx)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE33994E (en) * 1983-08-16 1992-07-14 Burroughs Wellcome Co. Pharmaceutical delivery system
US4749576A (en) * 1984-05-10 1988-06-07 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
US4624848A (en) * 1984-05-10 1986-11-25 Ciba-Geigy Corporation Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use
CA1239034A (en) * 1984-08-17 1988-07-12 Kelly L. Smith Delivery system
EP0297650A1 (en) * 1987-06-26 1989-01-04 Duphar International Research B.V Compositions with controlled zero-order delivery rate and method of preparing these compositions
US5219575A (en) * 1987-06-26 1993-06-15 Duphar International Research B.V. Compositions with controlled zero-order delivery rate and method of preparing these compositions
CN1053570C (zh) * 1987-10-07 2000-06-21 默尔多药物公司 哌啶子基链烷醇的药用组合物-减充血剂复方的制备方法
US4996061A (en) * 1987-10-07 1991-02-26 Merrell Dow Pharmaceuticals Inc. Pharmaceutical composition for piperidinoalkanol-decongestant combination
US4999226A (en) * 1988-06-01 1991-03-12 Merrell Dow Pharmaceuticals Inc. Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination
US5085865A (en) * 1989-04-12 1992-02-04 Warner-Lambert Company Sustained release pharmaceutical preparations containing an analgesic and a decongestant
US5198227A (en) * 1990-01-22 1993-03-30 Mcneil-Ppc, Inc. Dual subcoated simulated capsule medicament
KR100337985B1 (ko) * 1993-06-14 2002-11-23 얀센 파마슈티카 엔.브이. 아스테미졸및슈도에페드린의서방성필름-코팅정제
US5484607A (en) * 1993-10-13 1996-01-16 Horacek; H. Joseph Extended release clonidine formulation
US5451409A (en) * 1993-11-22 1995-09-19 Rencher; William F. Sustained release matrix system using hydroxyethyl cellulose and hydroxypropyl cellulose polymer blends
US5393765A (en) * 1993-12-13 1995-02-28 Hoffmann-La Roche Inc. Pharmaceutical compositions with constant erosion volume for zero order controlled release
DE19608423A1 (de) * 1996-03-05 1997-09-11 Merck Patent Gmbh Implantate mit phasenweiser Arzneistoffabgabe
US5948437A (en) * 1996-05-23 1999-09-07 Zeneca Limited Pharmaceutical compositions using thiazepine
EP0811374A1 (en) 1996-05-29 1997-12-10 Pfizer Inc. Combination dosage form comprising cetirizine and pseudoephedrine
US6197340B1 (en) 1998-05-28 2001-03-06 Medical Research Institute Controlled release lipoic acid
DE10031043A1 (de) 2000-06-26 2002-02-14 Bayer Ag Retardzubereitungen von Chinolonantibiotika und Verfahren zu ihrer Herstellung
KR100402053B1 (ko) * 2000-09-28 2003-10-17 한국화학연구원 항생제의 서방성 임플란트 제제
CA2464653C (en) 2001-10-29 2011-10-18 Therics, Inc. System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing
SA07280459B1 (ar) 2006-08-25 2011-07-20 بيورديو فارما إل. بي. أشكال جرعة صيدلانية للتناول عن طريق الفم مقاومة للعبث تشتمل على مسكن شبه أفيوني
US20090087490A1 (en) 2007-06-08 2009-04-02 Addrenex Pharmaceuticals, Inc. Extended release formulation and method of treating adrenergic dysregulation
KR101572336B1 (ko) 2010-12-22 2015-11-26 퍼듀 퍼머 엘피 케이싱된 탬퍼 저항성 제어 방출 투여 형태
CN103327969A (zh) 2010-12-23 2013-09-25 普渡制药公司 抗篡改固体口服剂型
US10751287B2 (en) 2013-03-15 2020-08-25 Purdue Pharma L.P. Tamper resistant pharmaceutical formulations
US10702548B2 (en) 2015-03-04 2020-07-07 Joelle Michele Forbes Compositions and methods for treating drug addiction

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1139869A (en) * 1966-01-06 1969-01-15 Moore Medicinal Products Ltd Improvements in or relating to tablets
US3965255A (en) * 1974-05-01 1976-06-22 E. E. Eljim Ecology Ltd. Controlled drug releasing preparations
SE418247B (sv) * 1975-11-17 1981-05-18 Haessle Ab Sett att framstella kroppar med reglerad frigoring av en aktiv komponent
US4122157A (en) * 1977-03-04 1978-10-24 Richardson-Merrell Inc. Nitrofurantoin sustained release tablet
GB2042888B (en) * 1979-03-05 1983-09-28 Teijin Ltd Preparation for administration to the mucosa of the oral or nasal cavity
US4291015A (en) * 1979-08-14 1981-09-22 Key Pharmaceuticals, Inc. Polymeric diffusion matrix containing a vasodilator

Also Published As

Publication number Publication date
KR900007311B1 (ko) 1990-10-08
IE832543L (en) 1984-05-01
IL70071A0 (en) 1984-01-31
EP0111144A1 (en) 1984-06-20
NO163356B (no) 1990-02-05
GR78740B (xx) 1984-10-02
AU554377B2 (en) 1986-08-21
NO833961L (no) 1984-05-02
PH20332A (en) 1986-12-02
NO163356C (no) 1990-05-16
DK499183D0 (da) 1983-10-31
KR840006765A (ko) 1984-12-03
DE3368011D1 (en) 1987-01-15
ES526901A0 (es) 1986-06-16
IE56182B1 (en) 1991-05-08
ES8607008A1 (es) 1986-06-16
CA1220137A (en) 1987-04-07
NZ206094A (en) 1986-10-08
AU2080383A (en) 1984-05-10
DK499183A (da) 1984-05-02
EP0111144B1 (en) 1986-12-03

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.