IL69849A - Ortho substituted dihydroxy-2(1h)quinazolinone-1-alkanoic acids,their preparation and pharmaceutical compositions containing them - Google Patents
Ortho substituted dihydroxy-2(1h)quinazolinone-1-alkanoic acids,their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL69849A IL69849A IL69849A IL6984983A IL69849A IL 69849 A IL69849 A IL 69849A IL 69849 A IL69849 A IL 69849A IL 6984983 A IL6984983 A IL 6984983A IL 69849 A IL69849 A IL 69849A
- Authority
- IL
- Israel
- Prior art keywords
- alkyl
- salts
- quinazolinone
- preparation
- pharmaceutical compositions
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 150000007513 acids Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 5
- 150000003839 salts Chemical class 0.000 abstract 3
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 abstract 2
- -1 amine salt Chemical class 0.000 abstract 2
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- 239000003513 alkali Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 235000001014 amino acid Nutrition 0.000 abstract 1
- 150000001414 amino alcohols Chemical class 0.000 abstract 1
- 125000003435 aroyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 150000001602 bicycloalkyls Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 239000000496 cardiotonic agent Substances 0.000 abstract 1
- 239000002327 cardiovascular agent Substances 0.000 abstract 1
- 229940125692 cardiovascular agent Drugs 0.000 abstract 1
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
- 125000001188 haloalkyl group Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- VNWKTOKETHGBQD-UHFFFAOYSA-N methane Natural products C VNWKTOKETHGBQD-UHFFFAOYSA-N 0.000 abstract 1
- 229940124550 renal vasodilator Drugs 0.000 abstract 1
- IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
- C07D239/80—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Manufacture Of Tobacco Products (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IL7924483A IL79244A (en) | 1982-09-30 | 1983-09-28 | 5,6-dialkoxy-2(1h)quinazolinone derivatives |
| IL7309784A IL73097A (en) | 1983-09-28 | 1984-09-26 | Substituted 2(1h)-quinazolinone-1-propionic acids and esters and their preparation |
| IL79244A IL79244A0 (en) | 1982-09-30 | 1986-06-26 | 5,6-dialkoxy-2(1h)quinazolinone derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/430,552 US4490374A (en) | 1982-09-30 | 1982-09-30 | 5,6-Dialkoxy-3,4-optionally substituted-2(1H)quinazolinones, composition and method of use |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL69849A0 IL69849A0 (en) | 1983-12-30 |
| IL69849A true IL69849A (en) | 1987-11-30 |
Family
ID=23708017
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL69849A IL69849A (en) | 1982-09-30 | 1983-09-28 | Ortho substituted dihydroxy-2(1h)quinazolinone-1-alkanoic acids,their preparation and pharmaceutical compositions containing them |
Country Status (13)
| Country | Link |
|---|---|
| KR (1) | KR840006218A (ro) |
| AT (2) | ATE58531T1 (ro) |
| DE (2) | DE3382013D1 (ro) |
| ES (4) | ES8503671A1 (ro) |
| HU (1) | HU192242B (ro) |
| IL (1) | IL69849A (ro) |
| NO (1) | NO833541L (ro) |
| NZ (1) | NZ205685A (ro) |
| PH (2) | PH19508A (ro) |
| RO (2) | RO87466B (ro) |
| SG (1) | SG31887G (ro) |
| YU (2) | YU196983A (ro) |
| ZW (1) | ZW20883A1 (ro) |
-
1983
- 1983-09-21 NZ NZ205685A patent/NZ205685A/en unknown
- 1983-09-28 PH PH29609A patent/PH19508A/en unknown
- 1983-09-28 IL IL69849A patent/IL69849A/xx unknown
- 1983-09-29 DE DE8686201912T patent/DE3382013D1/de not_active Expired - Lifetime
- 1983-09-29 AT AT86201912T patent/ATE58531T1/de not_active IP Right Cessation
- 1983-09-29 ZW ZW208/83A patent/ZW20883A1/xx unknown
- 1983-09-29 RO RO112200A patent/RO87466B/ro unknown
- 1983-09-29 NO NO833541A patent/NO833541L/no unknown
- 1983-09-29 RO RO83116473A patent/RO89787A/ro unknown
- 1983-09-29 ES ES526133A patent/ES8503671A1/es not_active Expired
- 1983-09-29 AT AT83305895T patent/ATE34979T1/de active
- 1983-09-29 DE DE8383305895T patent/DE3376978D1/de not_active Expired
- 1983-09-29 HU HU833392A patent/HU192242B/hu unknown
- 1983-09-30 KR KR1019830004638A patent/KR840006218A/ko not_active Ceased
- 1983-09-30 YU YU01969/83A patent/YU196983A/xx unknown
-
1984
- 1984-05-29 ES ES532920A patent/ES532920A0/es active Granted
- 1984-05-29 ES ES532918A patent/ES8507510A1/es not_active Expired
- 1984-05-29 ES ES532919A patent/ES8507511A1/es not_active Expired
-
1985
- 1985-05-24 PH PH32313A patent/PH21757A/en unknown
- 1985-12-11 YU YU01922/85A patent/YU192285A/xx unknown
-
1987
- 1987-03-31 SG SG318/87A patent/SG31887G/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR840006218A (ko) | 1984-11-22 |
| DE3376978D1 (en) | 1988-07-14 |
| PH19508A (en) | 1986-05-14 |
| RO87466A (ro) | 1985-08-31 |
| ZW20883A1 (en) | 1985-05-01 |
| ATE58531T1 (de) | 1990-12-15 |
| IL69849A0 (en) | 1983-12-30 |
| PH21757A (en) | 1988-02-18 |
| SG31887G (en) | 1987-07-17 |
| ES526133A0 (es) | 1985-03-16 |
| RO87466B (ro) | 1985-08-31 |
| ES532919A0 (es) | 1985-09-01 |
| YU192285A (en) | 1987-12-31 |
| ES532918A0 (es) | 1985-09-01 |
| ES8507512A1 (es) | 1985-09-01 |
| ES8507510A1 (es) | 1985-09-01 |
| ES8507511A1 (es) | 1985-09-01 |
| ES8503671A1 (es) | 1985-03-16 |
| HU192242B (en) | 1988-10-28 |
| NO833541L (no) | 1984-04-02 |
| YU196983A (en) | 1987-02-28 |
| ES532920A0 (es) | 1985-09-01 |
| DE3382013D1 (de) | 1991-01-03 |
| ATE34979T1 (de) | 1988-06-15 |
| NZ205685A (en) | 1987-03-31 |
| RO89787A (ro) | 1986-07-30 |
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