IL69199A - (5e)and (5z)-6a-carbaprostaglandin-i2-derivatives,process for their manufacture and pharmaceutical compositions containing them - Google Patents
(5e)and (5z)-6a-carbaprostaglandin-i2-derivatives,process for their manufacture and pharmaceutical compositions containing themInfo
- Publication number
- IL69199A IL69199A IL69199A IL6919983A IL69199A IL 69199 A IL69199 A IL 69199A IL 69199 A IL69199 A IL 69199A IL 6919983 A IL6919983 A IL 6919983A IL 69199 A IL69199 A IL 69199A
- Authority
- IL
- Israel
- Prior art keywords
- group
- denotes
- radical
- atoms
- hydrogen atom
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/72—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 spiro-condensed with carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
- C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/16—Radicals substituted by halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Medicinal Preparation (AREA)
- Ink Jet Recording Methods And Recording Media Thereof (AREA)
- Drawers Of Furniture (AREA)
- Inks, Pencil-Leads, Or Crayons (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823226550 DE3226550A1 (de) | 1982-07-13 | 1982-07-13 | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL69199A0 IL69199A0 (en) | 1983-11-30 |
| IL69199A true IL69199A (en) | 1987-08-31 |
Family
ID=6168531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL69199A IL69199A (en) | 1982-07-13 | 1983-07-12 | (5e)and (5z)-6a-carbaprostaglandin-i2-derivatives,process for their manufacture and pharmaceutical compositions containing them |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP0099538B1 (en, 2012) |
| JP (1) | JPS5921636A (en, 2012) |
| AT (1) | ATE67182T1 (en, 2012) |
| AU (1) | AU571841B2 (en, 2012) |
| CA (1) | CA1248525A (en, 2012) |
| CS (1) | CS235329B2 (en, 2012) |
| DD (1) | DD210027B3 (en, 2012) |
| DE (2) | DE3226550A1 (en, 2012) |
| DK (1) | DK163579C (en, 2012) |
| ES (1) | ES524058A0 (en, 2012) |
| FI (1) | FI77645C (en, 2012) |
| GR (1) | GR78873B (en, 2012) |
| HU (1) | HU191057B (en, 2012) |
| IE (1) | IE57233B1 (en, 2012) |
| IL (1) | IL69199A (en, 2012) |
| NZ (1) | NZ204875A (en, 2012) |
| PH (1) | PH25119A (en, 2012) |
| SU (1) | SU1316555A3 (en, 2012) |
| ZA (1) | ZA835109B (en, 2012) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3225287A1 (de) * | 1982-07-02 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3225288A1 (de) * | 1982-07-02 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS59141536A (ja) * | 1983-02-01 | 1984-08-14 | Sumitomo Chem Co Ltd | 新規ビシクロオクタン誘導体 |
| DE3405181A1 (de) * | 1984-02-10 | 1985-08-22 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4971987A (en) * | 1984-07-27 | 1990-11-20 | Schering Aktiengesellschaft | New carbacycline, process for their production and their use as a drug |
| DE3933523A1 (de) * | 1989-10-05 | 1991-04-11 | Schering Ag | Antimetastatisch wirkende mittel |
| EP0431571A3 (en) * | 1989-12-05 | 1992-01-02 | Sagami Chemical Research Center | Cis-bicyclo(4.3.0)non-2-ene derivatives |
| DE4104607A1 (de) * | 1991-02-12 | 1992-08-13 | Schering Ag | Prostacyclin- und carbacyclinderivate als mittel zur behandlung von fiebrigen erkrankungen |
| ATE306256T1 (de) | 1999-08-05 | 2005-10-15 | Teijin Ltd | Mittel zur besserung der neuropathie, die als wirkstoff stickstoffhaltige verbindungen enthalten |
| JP5271272B2 (ja) | 2006-11-16 | 2013-08-21 | ジェンムス ファーマ インコーポレイティド | Ａ型インフルエンザウィルス感染の治療のための薬剤としてのｅｐ２およびｅｐ４作動薬 |
| JP2013508282A (ja) | 2009-10-14 | 2013-03-07 | ジェンムス ファーマ インコーポレイティド | ウイルス感染のための併用療法処置 |
| US20160184387A1 (en) | 2013-08-09 | 2016-06-30 | Dominique Charmot | Compounds and methods for inhibiting phosphate transport |
| WO2020237096A1 (en) | 2019-05-21 | 2020-11-26 | Ardelyx, Inc. | Combination for lowering serum phosphate in a patient |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2038333B (en) * | 1978-01-26 | 1982-10-06 | Erba Farmitalia | 12 -formyl- (20 12)octanor-9-deoxy-9 -methylene pgi derivatives |
| US4705806A (en) * | 1978-02-13 | 1987-11-10 | Morton Jr Douglas R | Prostacyclin analogs |
| DE3048906A1 (de) * | 1980-12-19 | 1982-07-15 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| IE54303B1 (en) * | 1981-08-19 | 1989-08-16 | Merrell Dow France | Fluorinated diaminoalkene derivatives |
| GR77976B (en, 2012) * | 1982-03-12 | 1984-09-25 | Schering Ag | |
| DE3225287A1 (de) * | 1982-07-02 | 1984-01-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinamide, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1982
- 1982-07-13 DE DE19823226550 patent/DE3226550A1/de not_active Ceased
-
1983
- 1983-07-06 DD DD83252808A patent/DD210027B3/de not_active IP Right Cessation
- 1983-07-11 AU AU16718/83A patent/AU571841B2/en not_active Ceased
- 1983-07-11 EP EP83106792A patent/EP0099538B1/de not_active Expired - Lifetime
- 1983-07-11 GR GR71905A patent/GR78873B/el unknown
- 1983-07-11 DE DE8383106792T patent/DE3382408D1/de not_active Expired - Lifetime
- 1983-07-11 AT AT83106792T patent/ATE67182T1/de not_active IP Right Cessation
- 1983-07-12 JP JP58125615A patent/JPS5921636A/ja active Granted
- 1983-07-12 ES ES524058A patent/ES524058A0/es active Granted
- 1983-07-12 CA CA000432232A patent/CA1248525A/en not_active Expired
- 1983-07-12 IL IL69199A patent/IL69199A/xx not_active IP Right Cessation
- 1983-07-12 NZ NZ204875A patent/NZ204875A/en unknown
- 1983-07-12 HU HU832481A patent/HU191057B/hu not_active IP Right Cessation
- 1983-07-12 DK DK321283A patent/DK163579C/da not_active IP Right Cessation
- 1983-07-12 SU SU833615553A patent/SU1316555A3/ru active
- 1983-07-12 PH PH29208A patent/PH25119A/en unknown
- 1983-07-13 CS CS835301A patent/CS235329B2/cs unknown
- 1983-07-13 FI FI832557A patent/FI77645C/fi not_active IP Right Cessation
- 1983-07-13 ZA ZA835109A patent/ZA835109B/xx unknown
- 1983-07-13 IE IE1630/83A patent/IE57233B1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IE831630L (en) | 1984-01-13 |
| JPH0324457B2 (en, 2012) | 1991-04-03 |
| IL69199A0 (en) | 1983-11-30 |
| ES8403865A1 (es) | 1984-04-16 |
| CA1248525A (en) | 1989-01-10 |
| HU191057B (en) | 1986-12-28 |
| JPS5921636A (ja) | 1984-02-03 |
| ES524058A0 (es) | 1984-04-16 |
| SU1316555A3 (ru) | 1987-06-07 |
| DE3382408D1 (de) | 1991-10-17 |
| EP0099538B1 (de) | 1991-09-11 |
| ZA835109B (en) | 1984-08-29 |
| DK321283D0 (da) | 1983-07-12 |
| CS235329B2 (en) | 1985-05-15 |
| AU571841B2 (en) | 1988-04-28 |
| PH25119A (en) | 1991-02-19 |
| AU1671883A (en) | 1984-01-19 |
| FI77645B (fi) | 1988-12-30 |
| DK321283A (da) | 1984-01-14 |
| DD210027B3 (de) | 1990-07-18 |
| GR78873B (en, 2012) | 1984-10-02 |
| FI77645C (fi) | 1989-04-10 |
| IE57233B1 (en) | 1992-06-17 |
| EP0099538A1 (de) | 1984-02-01 |
| DK163579C (da) | 1992-08-03 |
| ATE67182T1 (de) | 1991-09-15 |
| DE3226550A1 (de) | 1984-01-19 |
| NZ204875A (en) | 1986-11-12 |
| FI832557A0 (fi) | 1983-07-13 |
| DK163579B (da) | 1992-03-16 |
| DD210027A5 (de) | 1984-05-30 |
| FI832557A7 (fi) | 1984-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RH | Patent void |