IL68825A0 - Dynorphin amide analogs - Google Patents

Dynorphin amide analogs

Info

Publication number
IL68825A0
IL68825A0 IL68825A IL6882583A IL68825A0 IL 68825 A0 IL68825 A0 IL 68825A0 IL 68825 A IL68825 A IL 68825A IL 6882583 A IL6882583 A IL 6882583A IL 68825 A0 IL68825 A0 IL 68825A0
Authority
IL
Israel
Prior art keywords
dynorphin
amino acids
compounds
amide analogs
new compounds
Prior art date
Application number
IL68825A
Other languages
English (en)
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Publication of IL68825A0 publication Critical patent/IL68825A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Polyamides (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL68825A 1982-06-10 1983-05-31 Dynorphin amide analogs IL68825A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/387,005 US4462941A (en) 1982-06-10 1982-06-10 Dynorphin amide analogs

Publications (1)

Publication Number Publication Date
IL68825A0 true IL68825A0 (en) 1983-09-30

Family

ID=23528034

Family Applications (1)

Application Number Title Priority Date Filing Date
IL68825A IL68825A0 (en) 1982-06-10 1983-05-31 Dynorphin amide analogs

Country Status (15)

Country Link
US (1) US4462941A (ja)
EP (1) EP0096592B1 (ja)
JP (1) JPS5925365A (ja)
KR (1) KR840005080A (ja)
AT (1) ATE22449T1 (ja)
AU (1) AU1448983A (ja)
CA (1) CA1241645A (ja)
DE (1) DE3366428D1 (ja)
DK (1) DK262683A (ja)
FI (1) FI832095L (ja)
IL (1) IL68825A0 (ja)
IS (1) IS2812A7 (ja)
NO (1) NO832107L (ja)
PT (1) PT76860B (ja)
ZA (1) ZA834189B (ja)

Families Citing this family (84)

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US4481191A (en) * 1983-03-30 1984-11-06 The Regents Of The University Of California Method for controlling blood pressure
US5242798A (en) * 1983-07-21 1993-09-07 Scripps Clinic And Research Foundation Synthetic polypeptides corresponding to portions of proteinoids translated from brain-specific mRNAs, receptors, methods and diagnostics using the same
US4900811A (en) * 1983-07-21 1990-02-13 Scripps Clinic And Research Foundation Synthetic polypeptides corresponding to portions of proteinoids translated from brain-specific mRNAs, receptors, methods and diagnostics using the same
ATE44751T1 (de) * 1983-12-22 1989-08-15 Yoshio Hosobuchi Zusammensetzungen zum behandeln von ischaemie im gehirn.
JPH0680079B2 (ja) * 1984-11-09 1994-10-12 エーザイ株式会社 ポリペプチド
US5017689A (en) * 1989-07-06 1991-05-21 Arizona Technology Development Corporation Dynorphin analogs specific for kappa opioid receptors
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US5817628A (en) * 1992-12-02 1998-10-06 The Rockefeller University Dynorphin a suppression of natural killer cell activity
US5482930A (en) * 1993-06-09 1996-01-09 The Regents Of The University Of California Anti-inflammatory composition and method with des-Tyr dynorphin and analogues
US6184208B1 (en) 1994-06-29 2001-02-06 Immunotech Developments Inc. Peptide, a method for its preparation and a pharmaceutical composition containing the peptide
JPH10511077A (ja) * 1994-08-26 1998-10-27 ナンシー、 エム． リー、 Ｎ末端基で切断されたダイノルフィン類似体を用いた鎮痛方法
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US6437092B1 (en) 1998-11-06 2002-08-20 Conjuchem, Inc. Conjugates of opioids and endogenous carriers
US6605648B1 (en) * 1999-04-06 2003-08-12 Phillips Plastics Corporation Sinterable structures and method
US6849714B1 (en) 1999-05-17 2005-02-01 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
US7601691B2 (en) 1999-05-17 2009-10-13 Conjuchem Biotechnologies Inc. Anti-obesity agents
US20090175821A1 (en) * 1999-05-17 2009-07-09 Bridon Dominique P Modified therapeutic peptides with extended half-lives in vivo
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US6514500B1 (en) * 1999-10-15 2003-02-04 Conjuchem, Inc. Long lasting synthetic glucagon like peptide {GLP-!}
ATE318835T1 (de) 1999-05-17 2006-03-15 Conjuchem Inc Schutz endogener, therapeutisch aktiver peptide vor peptidaseaktivität durch konjugation an blutbestandteile
US20040266673A1 (en) * 2002-07-31 2004-12-30 Peter Bakis Long lasting natriuretic peptide derivatives
US6887470B1 (en) 1999-09-10 2005-05-03 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
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US20070048228A1 (en) * 2003-08-06 2007-03-01 Elisabeth Arkenau-Maric Abuse-proofed dosage form
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WO2007053946A1 (en) * 2005-11-09 2007-05-18 Conjuchem Biotechnologies Inc. Method of treating diabetes and/or obesity with reduced nausea side effects using an insulinotropic peptide conjugated to albumin
EP1976876A4 (en) * 2005-12-22 2010-01-13 Conjuchem Biotechnologies Inc PROCESS FOR PRODUCING PREFORMED ALBUMIN CONJUGATES AND THERAPEUTIC AGENT
WO2008077194A1 (en) * 2006-12-22 2008-07-03 Xenome Ltd Receptor agonists
US20090099074A1 (en) * 2007-01-10 2009-04-16 Conjuchem Biotechnologies Inc. Modulating food intake
DE102007011485A1 (de) 2007-03-07 2008-09-11 Grünenthal GmbH Darreichungsform mit erschwertem Missbrauch
CA2708762A1 (en) * 2007-12-11 2009-06-18 Conjuchem Biotechnologies Inc. Formulation of insulinotropic peptide conjugates
US8383152B2 (en) 2008-01-25 2013-02-26 Gruenenthal Gmbh Pharmaceutical dosage form
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CA2766172C (en) 2009-07-22 2017-09-12 Lutz Barnscheid Oxidation-stabilized tamper-resistant dosage form
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US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
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US9617274B1 (en) 2011-08-26 2017-04-11 Demerx, Inc. Synthetic noribogaine
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US8877921B2 (en) 2012-01-25 2014-11-04 Demerx, Inc. Synthetic voacangine
US9150584B2 (en) 2012-01-25 2015-10-06 Demerx, Inc. Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
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US4396606A (en) * 1979-11-05 1983-08-02 Addiction Research Foundation Novel polypeptide analgesics
US4361553A (en) * 1981-05-18 1982-11-30 Regents Of The University Of California Therapeutic uses of dynorphin
JPS5815946A (ja) 1981-07-21 1983-01-29 Eisai Co Ltd 新規ヘプタデカペプタイド

Also Published As

Publication number Publication date
US4462941A (en) 1984-07-31
AU1448983A (en) 1983-12-15
DK262683D0 (da) 1983-06-09
IS2812A7 (is) 1983-10-07
JPS5925365A (ja) 1984-02-09
EP0096592A1 (en) 1983-12-21
DK262683A (da) 1983-12-11
NO832107L (no) 1983-12-12
JPH0427995B2 (ja) 1992-05-13
EP0096592B1 (en) 1986-09-24
PT76860A (en) 1983-07-01
ATE22449T1 (de) 1986-10-15
DE3366428D1 (en) 1986-10-30
ZA834189B (en) 1984-02-29
FI832095L (fi) 1983-12-11
CA1241645A (en) 1988-09-06
KR840005080A (ko) 1984-11-03
PT76860B (en) 1986-01-27
FI832095A0 (fi) 1983-06-10

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