IL68749A - Modified antigens,their preparation and vaccines containing them - Google Patents
Modified antigens,their preparation and vaccines containing themInfo
- Publication number
- IL68749A IL68749A IL68749A IL6874983A IL68749A IL 68749 A IL68749 A IL 68749A IL 68749 A IL68749 A IL 68749A IL 6874983 A IL6874983 A IL 6874983A IL 68749 A IL68749 A IL 68749A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- vaccines containing
- modified antigens
- antigens
- modified
- Prior art date
Links
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/11—Gonadotropin; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL7909383A IL79093A (en) | 1983-03-04 | 1983-05-20 | Antigenic modified polypeptides,their preparation and vaccines containing them |
IL8202083A IL82020A (en) | 1983-03-04 | 1983-05-20 | Antigenic modified zona pellucida and sperm polypeptides,their preparation and vaccines containing them |
IL79093A IL79093A0 (en) | 1983-03-04 | 1986-06-11 | Antigenic modified polypeptides,their preparation and vaccines containing them |
IL82020A IL82020A0 (en) | 1983-03-04 | 1987-03-26 | Antigenic modified polypeptides,their preparation and vaccines containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/472,190 US4526716A (en) | 1981-11-20 | 1983-03-04 | Antigenic modification of polypeptides |
Publications (1)
Publication Number | Publication Date |
---|---|
IL68749A true IL68749A (en) | 1988-07-31 |
Family
ID=23874533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL68749A IL68749A (en) | 1983-03-04 | 1983-05-20 | Modified antigens,their preparation and vaccines containing them |
Country Status (10)
Country | Link |
---|---|
US (1) | US4526716A (sv) |
EP (3) | EP0117934B1 (sv) |
JP (1) | JPS60500814A (sv) |
AU (3) | AU570004B2 (sv) |
DK (1) | DK167222B1 (sv) |
FI (1) | FI80603C (sv) |
GB (3) | GB2146646A (sv) |
GR (1) | GR79126B (sv) |
IL (1) | IL68749A (sv) |
WO (1) | WO1984003443A1 (sv) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6146633A (en) * | 1973-05-07 | 2000-11-14 | The Ohio State University | Method for treatment of antigenically modified polypeptides |
US6103243A (en) * | 1985-05-15 | 2000-08-15 | Biotechnology Australia Pty, Ltd | Oral vaccines |
CA1239346A (en) * | 1985-06-04 | 1988-07-19 | Gursaran P. Talwar | Birth control vaccine |
US4855285A (en) * | 1985-12-04 | 1989-08-08 | The Ohio State University Research Foundation | Antigenic modification of polypeptides |
US5817753A (en) * | 1985-12-04 | 1998-10-06 | The Ohio State University Research Foundation | Antigenic modification of polypeptides |
US4795634A (en) * | 1986-03-14 | 1989-01-03 | Aphton Corporation | Method for contraception by immunization against the zona pellucida |
US5096706A (en) * | 1986-03-25 | 1992-03-17 | National Research Development Corporation | Antigen-based treatment for adiposity |
NZ221306A (en) * | 1986-08-15 | 1990-02-26 | Commw Scient Ind Res Org | 2-component immunoadjuvant comprising a mycobacterial free immunoadjuvant oil and a polycationic polyelectrolyte immunoadjuvant and vaccines thereof |
EP0282501A4 (en) * | 1986-08-18 | 1989-11-14 | Bunge Australia | REGULATION OF ANIMAL REPRODUCTION. |
US5110794A (en) * | 1987-01-30 | 1992-05-05 | Abbott Laboratories | Method of immunization with partially cationized substances and said partially cationized substances |
US5346990A (en) * | 1987-04-08 | 1994-09-13 | Cytogam, Inc. | Sex-associated membrane proteins and methods for increasing the probability that offspring will be of a desired sex |
US5021244A (en) * | 1988-12-06 | 1991-06-04 | Cytogam, Inc. | Sex-associated membrane antibodies and their use for increasing the probability that offspring will be of a desired sex |
US4996297A (en) * | 1987-10-07 | 1991-02-26 | Zonagen, Inc. | Recombinantly expressed rabbit zona pellucida polypeptides |
US6610669B1 (en) | 1987-09-18 | 2003-08-26 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
BE1001013A4 (fr) * | 1987-10-22 | 1989-06-13 | Icp Internat Inst Of Cellular | Derives de synergimycines de types a et b, procede pour leur preparation et utilisation de ceux-ci. |
US5002883A (en) * | 1987-10-30 | 1991-03-26 | Abbott Laboratories | Covalent attachment of antibodies and antigens to solid phases using extended length heterobifunctional coupling agents |
US5023077A (en) * | 1989-01-24 | 1991-06-11 | Aphton Corporation | Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease |
ES2063912T3 (es) * | 1989-01-24 | 1995-01-16 | Aphton Corp | Composiciones inmunogenicas frente a peptidos de gastrina. |
US6861510B1 (en) * | 1989-01-24 | 2005-03-01 | Aphton Corporation | Immunogenic compositions against gastrin peptides |
US5786457A (en) * | 1989-02-23 | 1998-07-28 | Colorado State University Research Foundation | Hormone-nuclease compounds and method for regulating hormone related diseases |
WO1990009799A1 (en) * | 1989-02-23 | 1990-09-07 | Colorado State University Research Foundation | GnRH ANALOGS FOR DESTROYING GONADOTROPHS |
US6326467B1 (en) * | 1989-02-23 | 2001-12-04 | Colorado State University Research Foundation | Hormone-recombinant toxin compounds and methods for using same |
US5641487A (en) * | 1989-06-12 | 1997-06-24 | The Government Of The United States Of America As Represented By The Secretary Department Of Health And Human Services | Contraceptive vaccine based on alloimmunization with zona pellucida polypeptides |
FR2656626B1 (fr) * | 1989-12-29 | 1994-08-12 | Pasteur Institut | Fragment peptidique comprenant une sequence issue de la proteine 28 kda de schistosoma mansoni et compositions vaccinantes et/ou therapeutiques comprenant ledit fragment. |
AU2254792A (en) * | 1991-07-01 | 1993-02-11 | Blood Center Of Southeastern Wisconsin, The | Pen polymorphism of human platelet membrane glycoprotein iiia and diagnostic and therapeutic application thereof |
AU686999B2 (en) | 1992-04-07 | 1998-02-19 | Scripps Research Institute, The | Process for preparing modified proteins |
JPH08502062A (ja) * | 1992-09-30 | 1996-03-05 | ジ・オハイオ・ステイト・ユニバーシティ・リサーチ・ファウンデーション | ワクチンおよび抗原結合体 |
US20050277582A1 (en) * | 1993-07-20 | 2005-12-15 | Nett Torrance M | Method for inactivating gonadotrophs |
US5468494A (en) * | 1993-11-12 | 1995-11-21 | Aphton Corp. | Immunogenic compositions against human gastrin 17 |
US5688506A (en) * | 1994-01-27 | 1997-11-18 | Aphton Corp. | Immunogens against gonadotropin releasing hormone |
JP2947503B2 (ja) * | 1994-03-02 | 1999-09-13 | エーザイ株式会社 | アリルキノン誘導体の製造方法および中間体 |
US5869057A (en) * | 1995-06-07 | 1999-02-09 | Rock; Edwin P. | Recombinant vaccines to break self-tolerance |
ES2108614B1 (es) * | 1995-07-12 | 1998-07-16 | Oncina Fco Javier Martin | Vacunas polimerizadas. |
US5610136A (en) * | 1996-01-30 | 1997-03-11 | Milkhaus Laboratory, Inc. | Method for treatment of benign prostatic hypertrophy |
JP2000504692A (ja) * | 1996-02-08 | 2000-04-18 | アフトン・コーポレーション | 胃腸癌治療用の免疫学的方法 |
ATE245163T1 (de) * | 1996-05-03 | 2003-08-15 | Univ Jefferson | Impfstoff gegen metastasierenden kolorektalkrebs. |
DE19622289A1 (de) * | 1996-05-23 | 1997-11-27 | Schering Ag | Zona Pellucida Proteine zur Kontrazeption |
US6331610B1 (en) | 1997-04-25 | 2001-12-18 | Metatron, Inc. | Method for treating AIDS and HIV infection using select peptides from the beta subunit of human chorionic gonadotropin |
US20040001842A1 (en) * | 1997-05-12 | 2004-01-01 | Dov Michaeli | Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors |
ES2227833T3 (es) * | 1997-05-12 | 2005-04-01 | Aphton Corporation | Composiciones inmunogenicas para el receptor cck-b/gastrina y metodos para el tratamiento de tumores. |
DK0894498T3 (da) | 1997-07-01 | 2006-08-28 | Vlp Watertown Ltd Partnership | Fremgangsmåde til bestemmelse af kön af pattedyr-afkom |
US7135333B1 (en) | 1997-08-07 | 2006-11-14 | Thomas Jefferson University | Compositions that specifically bind to colorectal cancer cells and methods of using the same |
US6120995A (en) * | 1997-08-07 | 2000-09-19 | Thomas Jefferson University | Compositions that specifically bind to colorectal cancer cells and methods of using the same |
DK1659179T3 (da) | 1998-02-05 | 2011-10-10 | Glaxosmithkline Biolog Sa | Tumor-associerede antigenderivater fra MAGE-familien og nucleinsyresekvenser kodende for dem anvendt til fremstilling af fusionsproteiner og sammensætninger til vaccination |
US20030068326A1 (en) * | 1998-05-15 | 2003-04-10 | Aphton Corporation | Method for the treatment of gastroesophageal reflux disease |
JP2002515458A (ja) * | 1998-05-15 | 2002-05-28 | アフトン・コーポレーシヨン | 高ガストリン血症の予防および処置 |
ATE469242T1 (de) * | 2000-03-27 | 2010-06-15 | Univ Jefferson | Zusammensetzungen und methoden zur identifizierung und zum targeting von krebszellen aus dem verdauungskanal |
US6783761B2 (en) | 2000-05-05 | 2004-08-31 | Aphton Corporation | Chimeric peptide immunogens |
AU2001292728A1 (en) * | 2000-09-18 | 2002-03-26 | Thomas Jefferson University | Compositions and methods for identifying and targeting stomach and esophageal cancer cells |
CA2441228A1 (en) * | 2001-03-23 | 2002-10-03 | Aphton Corporation | Combination treatment of pancreatic cancer |
US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
CA2450898A1 (en) * | 2001-07-09 | 2003-01-23 | Aphton Corporation | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
US6810583B2 (en) * | 2001-08-07 | 2004-11-02 | International Business Machines Corporation | Coupling of conductive vias to complex power-signal substructures |
WO2004000217A2 (en) | 2002-06-20 | 2003-12-31 | The Trustees Of The University Of Pennsylvania | Vaccines for suppressing ige-mediated allergic disease and methods for using the same |
US20060020119A1 (en) * | 2004-03-29 | 2006-01-26 | Stephen Grimes | Monoclonal antibodies to gastrin hormone |
CA2520010C (en) * | 2003-03-28 | 2012-07-10 | Aphton Corporation | Gastrin hormone immunoassays |
JP2008513536A (ja) * | 2004-09-22 | 2008-05-01 | レセプター バイオロジックス インコーポレイテッド | プロガストリンに対するモノクローナル抗体 |
WO2010036652A1 (en) * | 2008-09-23 | 2010-04-01 | Thomas Jefferson University | Cancer vaccines against mucosal antigens and methods of making and using the same |
US20120251509A1 (en) | 2009-10-22 | 2012-10-04 | Waldman Scott A | Cell-based anti-cancer compositions and methods of making and using the same |
CA2919907A1 (en) | 2012-08-02 | 2014-02-06 | The Board Of Trustees Of The Leland Stanford Junior University | Peptide vaccines based on the egfrviii sequence for the treatment of tumors |
CA3066756A1 (en) | 2017-06-15 | 2018-12-20 | Cancer Advances Inc. | Compositions and methods for inducing humoral and cellular immunities against tumors and cancer |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2301532A (en) * | 1938-08-18 | 1942-11-10 | Parke Davis & Co | Biological product and process of obtaining same |
US2372066A (en) * | 1940-12-23 | 1945-03-20 | Parke Davis & Co | Biological product and process of obtaining same |
US2388260A (en) * | 1942-03-11 | 1945-11-06 | Ernst A H Friedheim | Therapeutically active aromatic diazo compounds and derivatives thereof |
US2744890A (en) * | 1952-12-19 | 1956-05-08 | Nat Dairy Res Lab Inc | Proteinaceous composition and method of making the same |
US3317400A (en) * | 1964-11-23 | 1967-05-02 | Upjohn Co | Enzymatic modification of bovine growth hormone by proteolytic streptomycete cell extracts |
CH622426A5 (en) * | 1973-05-07 | 1981-04-15 | Univ Ohio | Contraceptive composition |
US4201770A (en) * | 1973-05-07 | 1980-05-06 | The Ohio State University | Antigenic modification of polypeptides |
US4302386A (en) * | 1978-08-25 | 1981-11-24 | The Ohio State University | Antigenic modification of polypeptides |
US4384995A (en) * | 1980-01-16 | 1983-05-24 | The Ohio State University | Antigenic modification of polypeptides |
US4179337A (en) * | 1973-07-20 | 1979-12-18 | Davis Frank F | Non-immunogenic polypeptides |
IN140168B (sv) * | 1974-10-14 | 1976-09-25 | All India Inst Med | |
CA1054937A (en) * | 1975-01-28 | 1979-05-22 | Gursaran P. Talwar | Antipregnancy vaccine |
NZ182272A (en) * | 1975-10-14 | 1985-03-20 | Univ Ohio State | Modified polypeptides for the immunological control of fertility,and pharmaceutical compositions |
FR2334107A1 (fr) * | 1975-12-05 | 1977-07-01 | Pasteur Institut | Procede de couplage de substances biologiques par des liaisons covalentes |
US4122166A (en) * | 1976-08-17 | 1978-10-24 | Philips Roxane, Inc. | Injectable contraceptive and method |
US4123519A (en) * | 1976-08-17 | 1978-10-31 | Philips Roxane, Inc. | Injectable contraceptive vaccine and method |
US4234561A (en) * | 1978-02-06 | 1980-11-18 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4256629A (en) * | 1978-02-06 | 1981-03-17 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4313871A (en) * | 1978-02-06 | 1982-02-02 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4268435A (en) * | 1979-02-06 | 1981-05-19 | Research Corporation | Chorionic gonadotropin derived antigen for early pregnancy test and contraceptive vaccine |
US4310455A (en) * | 1979-04-17 | 1982-01-12 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4253996A (en) * | 1980-02-13 | 1981-03-03 | Scripps Clinic And Research Foundation | Immunochemical conjugates: method and composition |
US4320386A (en) | 1980-07-30 | 1982-03-16 | General Electric Company | Selection and power reset circuit |
FR2525592B1 (sv) * | 1982-04-26 | 1984-09-14 | Pasteur Institut |
-
1983
- 1983-03-04 US US06/472,190 patent/US4526716A/en not_active Expired - Lifetime
- 1983-05-18 WO PCT/US1983/000777 patent/WO1984003443A1/en active IP Right Grant
- 1983-05-18 GB GB08425710A patent/GB2146646A/en not_active Withdrawn
- 1983-05-18 JP JP58502046A patent/JPS60500814A/ja active Granted
- 1983-05-18 AU AU17040/83A patent/AU570004B2/en not_active Ceased
- 1983-05-20 EP EP83302888A patent/EP0117934B1/en not_active Expired
- 1983-05-20 EP EP86110378A patent/EP0213391A3/en not_active Withdrawn
- 1983-05-20 IL IL68749A patent/IL68749A/xx unknown
- 1983-05-20 EP EP86110377A patent/EP0210628A3/en not_active Withdrawn
- 1983-05-24 GR GR71441A patent/GR79126B/el unknown
-
1984
- 1984-11-01 FI FI844288A patent/FI80603C/sv not_active IP Right Cessation
- 1984-11-02 DK DK521584A patent/DK167222B1/da not_active IP Right Cessation
-
1986
- 1986-08-06 GB GB08619232A patent/GB2178041B/en not_active Expired
- 1986-08-06 GB GB08619233A patent/GB2178042B/en not_active Expired
-
1987
- 1987-04-13 AU AU71490/87A patent/AU588448B2/en not_active Ceased
- 1987-04-13 AU AU71495/87A patent/AU594453B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
EP0213391A2 (en) | 1987-03-11 |
AU7149587A (en) | 1987-09-10 |
GB2178041B (en) | 1988-01-06 |
GB8619232D0 (en) | 1986-09-17 |
GB8425710D0 (en) | 1984-12-05 |
JPS60500814A (ja) | 1985-05-30 |
AU588448B2 (en) | 1989-09-14 |
GB2178041A (en) | 1987-02-04 |
EP0117934B1 (en) | 1988-07-20 |
DK167222B1 (da) | 1993-09-20 |
FI844288L (fi) | 1984-11-01 |
AU594453B2 (en) | 1990-03-08 |
AU7149087A (en) | 1987-08-06 |
EP0210628A2 (en) | 1987-02-04 |
GB2178042B (en) | 1988-01-06 |
EP0213391A3 (en) | 1989-02-01 |
DK521584A (da) | 1984-11-02 |
GB8619233D0 (en) | 1986-09-17 |
DK521584D0 (da) | 1984-11-02 |
AU1704083A (en) | 1984-09-28 |
AU570004B2 (en) | 1988-03-03 |
EP0210628A3 (en) | 1989-02-08 |
US4526716A (en) | 1985-07-02 |
GB2146646A (en) | 1985-04-24 |
EP0117934A1 (en) | 1984-09-12 |
WO1984003443A1 (en) | 1984-09-13 |
FI80603C (sv) | 1990-07-10 |
FI844288A0 (fi) | 1984-11-01 |
JPH0557999B2 (sv) | 1993-08-25 |
GR79126B (sv) | 1984-10-02 |
GB2178042A (en) | 1987-02-04 |
FI80603B (fi) | 1990-03-30 |
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