DK521584A - Antigener, modificerede antigener og antigent modificerede polypeptider, fremgangsmaade til fremstilling heraf og vacciner indeholdende disse - Google Patents
Antigener, modificerede antigener og antigent modificerede polypeptider, fremgangsmaade til fremstilling heraf og vacciner indeholdende disse Download PDFInfo
- Publication number
- DK521584A DK521584A DK521584A DK521584A DK521584A DK 521584 A DK521584 A DK 521584A DK 521584 A DK521584 A DK 521584A DK 521584 A DK521584 A DK 521584A DK 521584 A DK521584 A DK 521584A
- Authority
- DK
- Denmark
- Prior art keywords
- modified
- antigenes
- antigens
- immunogenic
- producing
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 4
- 229960005486 vaccine Drugs 0.000 title abstract 2
- 238000000034 method Methods 0.000 title 1
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 230000002163 immunogen Effects 0.000 abstract 4
- 241001465754 Metazoa Species 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 3
- 102000004169 proteins and genes Human genes 0.000 abstract 3
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- PRAKJMSDJKAYCZ-UHFFFAOYSA-N squalane Chemical compound CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C PRAKJMSDJKAYCZ-UHFFFAOYSA-N 0.000 abstract 3
- 229920000642 polymer Polymers 0.000 abstract 2
- YYGNTYWPHWGJRM-UHFFFAOYSA-N (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene Chemical compound CC(C)=CCCC(C)=CCCC(C)=CCCC=C(C)CCC=C(C)CCC=C(C)C YYGNTYWPHWGJRM-UHFFFAOYSA-N 0.000 abstract 1
- BHEOSNUKNHRBNM-UHFFFAOYSA-N Tetramethylsqualene Natural products CC(=C)C(C)CCC(=C)C(C)CCC(C)=CCCC=C(C)CCC(C)C(=C)CCC(C)C(C)=C BHEOSNUKNHRBNM-UHFFFAOYSA-N 0.000 abstract 1
- LUXUAZKGQZPOBZ-SAXJAHGMSA-N [(3S,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl] (Z)-octadec-9-enoate Chemical compound CCCCCCCC\C=C/CCCCCCCC(=O)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@@H]1O LUXUAZKGQZPOBZ-SAXJAHGMSA-N 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 230000035558 fertility Effects 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 210000000582 semen Anatomy 0.000 abstract 1
- 229940032094 squalane Drugs 0.000 abstract 1
- 229940031439 squalene Drugs 0.000 abstract 1
- TUHBEKDERLKLEC-UHFFFAOYSA-N squalene Natural products CC(=CCCC(=CCCC(=CCCC=C(/C)CCC=C(/C)CC=C(C)C)C)C)C TUHBEKDERLKLEC-UHFFFAOYSA-N 0.000 abstract 1
- 210000004340 zona pellucida Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1075—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of amino acids or peptide residues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0006—Contraceptive vaccins; Vaccines against sex hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/5555—Muramyl dipeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6012—Haptens, e.g. di- or trinitrophenyl (DNP, TNP)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/806—Antigenic peptides or proteins
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/11—Gonadotropin; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US47219083 | 1983-03-04 | ||
US06/472,190 US4526716A (en) | 1981-11-20 | 1983-03-04 | Antigenic modification of polypeptides |
US8300777 | 1983-05-18 | ||
PCT/US1983/000777 WO1984003443A1 (en) | 1983-03-04 | 1983-05-18 | Antigenic modification of polypeptides |
Publications (3)
Publication Number | Publication Date |
---|---|
DK521584A true DK521584A (da) | 1984-11-02 |
DK521584D0 DK521584D0 (da) | 1984-11-02 |
DK167222B1 DK167222B1 (da) | 1993-09-20 |
Family
ID=23874533
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK521584A DK167222B1 (da) | 1983-03-04 | 1984-11-02 | Antigen, fremgangsmaade til fremstilling heraf og vaccine indeholdende dette |
Country Status (10)
Country | Link |
---|---|
US (1) | US4526716A (da) |
EP (3) | EP0210628A3 (da) |
JP (1) | JPS60500814A (da) |
AU (3) | AU570004B2 (da) |
DK (1) | DK167222B1 (da) |
FI (1) | FI80603C (da) |
GB (3) | GB2146646A (da) |
GR (1) | GR79126B (da) |
IL (1) | IL68749A (da) |
WO (1) | WO1984003443A1 (da) |
Families Citing this family (61)
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US4855285A (en) * | 1985-12-04 | 1989-08-08 | The Ohio State University Research Foundation | Antigenic modification of polypeptides |
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US4256629A (en) * | 1978-02-06 | 1981-03-17 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4313871A (en) * | 1978-02-06 | 1982-02-02 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4234561A (en) * | 1978-02-06 | 1980-11-18 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4268435A (en) * | 1979-02-06 | 1981-05-19 | Research Corporation | Chorionic gonadotropin derived antigen for early pregnancy test and contraceptive vaccine |
US4310455A (en) * | 1979-04-17 | 1982-01-12 | Research Corporation | Antigen for early pregnancy test and contraceptive vaccine |
US4253996A (en) * | 1980-02-13 | 1981-03-03 | Scripps Clinic And Research Foundation | Immunochemical conjugates: method and composition |
US4320386A (en) | 1980-07-30 | 1982-03-16 | General Electric Company | Selection and power reset circuit |
FR2525592B1 (da) * | 1982-04-26 | 1984-09-14 | Pasteur Institut |
-
1983
- 1983-03-04 US US06/472,190 patent/US4526716A/en not_active Expired - Lifetime
- 1983-05-18 JP JP58502046A patent/JPS60500814A/ja active Granted
- 1983-05-18 WO PCT/US1983/000777 patent/WO1984003443A1/en active IP Right Grant
- 1983-05-18 GB GB08425710A patent/GB2146646A/en not_active Withdrawn
- 1983-05-18 AU AU17040/83A patent/AU570004B2/en not_active Ceased
- 1983-05-20 EP EP86110377A patent/EP0210628A3/en not_active Withdrawn
- 1983-05-20 EP EP86110378A patent/EP0213391A3/en not_active Withdrawn
- 1983-05-20 IL IL68749A patent/IL68749A/xx unknown
- 1983-05-20 EP EP83302888A patent/EP0117934B1/en not_active Expired
- 1983-05-24 GR GR71441A patent/GR79126B/el unknown
-
1984
- 1984-11-01 FI FI844288A patent/FI80603C/fi not_active IP Right Cessation
- 1984-11-02 DK DK521584A patent/DK167222B1/da not_active IP Right Cessation
-
1986
- 1986-08-06 GB GB08619232A patent/GB2178041B/en not_active Expired
- 1986-08-06 GB GB08619233A patent/GB2178042B/en not_active Expired
-
1987
- 1987-04-13 AU AU71495/87A patent/AU594453B2/en not_active Ceased
- 1987-04-13 AU AU71490/87A patent/AU588448B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
FI80603B (fi) | 1990-03-30 |
FI844288L (fi) | 1984-11-01 |
AU7149087A (en) | 1987-08-06 |
EP0213391A3 (en) | 1989-02-01 |
WO1984003443A1 (en) | 1984-09-13 |
GB2178042B (en) | 1988-01-06 |
GB2178041A (en) | 1987-02-04 |
EP0210628A3 (en) | 1989-02-08 |
US4526716A (en) | 1985-07-02 |
JPH0557999B2 (da) | 1993-08-25 |
AU7149587A (en) | 1987-09-10 |
EP0213391A2 (en) | 1987-03-11 |
EP0117934A1 (en) | 1984-09-12 |
IL68749A (en) | 1988-07-31 |
FI80603C (fi) | 1990-07-10 |
EP0117934B1 (en) | 1988-07-20 |
AU570004B2 (en) | 1988-03-03 |
GB2178042A (en) | 1987-02-04 |
AU588448B2 (en) | 1989-09-14 |
GB2178041B (en) | 1988-01-06 |
EP0210628A2 (en) | 1987-02-04 |
GB8619232D0 (en) | 1986-09-17 |
GR79126B (da) | 1984-10-02 |
AU1704083A (en) | 1984-09-28 |
AU594453B2 (en) | 1990-03-08 |
GB2146646A (en) | 1985-04-24 |
JPS60500814A (ja) | 1985-05-30 |
DK167222B1 (da) | 1993-09-20 |
GB8619233D0 (en) | 1986-09-17 |
DK521584D0 (da) | 1984-11-02 |
GB8425710D0 (en) | 1984-12-05 |
FI844288A0 (fi) | 1984-11-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B1 | Patent granted (law 1993) | ||
PBP | Patent lapsed |