ATE505202T1 - Immunologische methoden zur behandlung von gastrointestinalem krebs - Google Patents

Immunologische methoden zur behandlung von gastrointestinalem krebs

Info

Publication number
ATE505202T1
ATE505202T1 AT97905858T AT97905858T ATE505202T1 AT E505202 T1 ATE505202 T1 AT E505202T1 AT 97905858 T AT97905858 T AT 97905858T AT 97905858 T AT97905858 T AT 97905858T AT E505202 T1 ATE505202 T1 AT E505202T1
Authority
AT
Austria
Prior art keywords
treating gastrointestinal
gastrointestinal cancer
immunological methods
gastrin
amidated
Prior art date
Application number
AT97905858T
Other languages
English (en)
Inventor
Philip Gevas
Stephen Karr
Stephen Grimes
Dov Michaeli
Susan Watson
Original Assignee
Cancer Advances Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cancer Advances Inc filed Critical Cancer Advances Inc
Application granted granted Critical
Publication of ATE505202T1 publication Critical patent/ATE505202T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/595—Gastrins; Cholecystokinins [CCK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT97905858T 1996-02-08 1997-02-07 Immunologische methoden zur behandlung von gastrointestinalem krebs ATE505202T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1141196P 1996-02-08 1996-02-08
PCT/US1997/002029 WO1997028821A1 (en) 1996-02-08 1997-02-07 Immunological methods for the treatment of gastrointestinal cancer

Publications (1)

Publication Number Publication Date
ATE505202T1 true ATE505202T1 (de) 2011-04-15

Family

ID=21750270

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97905858T ATE505202T1 (de) 1996-02-08 1997-02-07 Immunologische methoden zur behandlung von gastrointestinalem krebs

Country Status (9)

Country Link
US (1) US20050025770A1 (de)
EP (1) EP0889735B1 (de)
JP (3) JP2000504692A (de)
AT (1) ATE505202T1 (de)
DE (1) DE69740173D1 (de)
DK (1) DK0889735T3 (de)
ES (1) ES2361474T3 (de)
PT (1) PT889735E (de)
WO (1) WO1997028821A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE505202T1 (de) * 1996-02-08 2011-04-15 Cancer Advances Inc Immunologische methoden zur behandlung von gastrointestinalem krebs
ES2227833T3 (es) * 1997-05-12 2005-04-01 Aphton Corporation Composiciones inmunogenicas para el receptor cck-b/gastrina y metodos para el tratamiento de tumores.
US20040001842A1 (en) * 1997-05-12 2004-01-01 Dov Michaeli Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors
AU4080399A (en) * 1998-05-15 1999-12-06 Aphton Corporation Prevention and treatment of hypergastrinemia
EP1839673A3 (de) * 1998-05-15 2007-11-07 Receptor Biologix, Inc. Vorbeugung und Behandlung von Hypergastrinämie
US20030068326A1 (en) * 1998-05-15 2003-04-10 Aphton Corporation Method for the treatment of gastroesophageal reflux disease
JP2005508838A (ja) * 2001-03-23 2005-04-07 アフトン コーポレーション 膵癌の組合せ治療
US20090191232A1 (en) * 2001-05-04 2009-07-30 Gevas Philip C Combination therapy for the treatment of tumors
JP2004536835A (ja) * 2001-07-09 2004-12-09 アフトン コーポレーション 肝臓、肺および食道の癌性ならびに前癌性状態の治療および防止
US20050169979A1 (en) * 2002-07-03 2005-08-04 Dov Michaeli Liposomal vaccine
JP4689597B2 (ja) 2003-03-28 2011-05-25 レセプター バイオロジックス インク． ガストリンホルモン免疫アッセイ
EP1730193A2 (de) * 2004-03-29 2006-12-13 Receptor Biologix, Inc. Monoklonale antikörper gegen gastrinhormon
KR101333168B1 (ko) 2004-09-22 2013-11-28 리셉터 바이오로직스 인크 프로가스트린에 대한 모노클로날 항체
JP5558660B2 (ja) 2007-05-11 2014-07-23 日東電工株式会社 両面接着性感圧接着シート
US8674064B2 (en) * 2010-03-03 2014-03-18 Onkologix Ltd Immunogenic compositions against human progastrin peptides
CN101797382B (zh) 2010-03-03 2013-11-20 戚胜美 抗人前胃液素多肽免疫组合物
ES2665780T3 (es) * 2013-05-21 2018-04-27 Tyg Oncology Ltd. Composición inmunogénica de péptido de gastrina
US12150978B2 (en) 2017-06-15 2024-11-26 Cancer Advances Inc. Compositions and methods for preventing tumors and cancer
WO2018232230A1 (en) 2017-06-15 2018-12-20 Cancer Advances Inc. Compositions and methods for inducing humoral and cellular immunities against tumors and cancer

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US68326A (en) * 1867-08-27 Alcibiades j
US20119A (en) * 1858-04-27 Improvement in raking and delivering attachments to harvesters
US69966A (en) * 1867-10-22 Joseph chadwick
US95028A (en) * 1869-09-21 Improved process for preserving eggs
US1842A (en) * 1840-10-31 Machine fob cutting corks
US39911A (en) * 1863-09-15 Improvement in corset skirt-supporters
US21786A (en) * 1858-10-12 Improvement in the manufacture of sugar
US187152A (en) * 1877-02-06 Improvement in clothes-wringers
US140962A (en) * 1873-07-15 Improvement in feeding paper to printing-presses
US58040A (en) * 1866-09-18 Improvement in making bolts
US86941A (en) * 1869-02-16 Improvement in corn-planter
US91574A (en) * 1869-06-22 Improvement in water-closet valves
US4526716A (en) * 1981-11-20 1985-07-02 The Ohio State University Antigenic modification of polypeptides
US4384995A (en) * 1980-01-16 1983-05-24 The Ohio State University Antigenic modification of polypeptides
US4691006A (en) * 1983-03-04 1987-09-01 Ohio State University Antigenic modification of polypeptides
IT1179894B (it) * 1984-12-27 1987-09-16 Rotta Research Lab Proglumide e composizioni farmaceutiche che la contengono per l impiego nella terapia di affezioni neoplastiche
US6861510B1 (en) * 1989-01-24 2005-03-01 Aphton Corporation Immunogenic compositions against gastrin peptides
ES2063912T3 (es) * 1989-01-24 1995-01-16 Aphton Corp Composiciones inmunogenicas frente a peptidos de gastrina.
US5023077A (en) * 1989-01-24 1991-06-11 Aphton Corporation Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease
US5319073A (en) * 1992-02-07 1994-06-07 The United States Of America, As Represented By The Department Of Health & Human Services Method of purifying cholecystokinin receptor protein
US5759551A (en) * 1993-04-27 1998-06-02 United Biomedical, Inc. Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines
US5468494A (en) 1993-11-12 1995-11-21 Aphton Corp. Immunogenic compositions against human gastrin 17
US5688506A (en) * 1994-01-27 1997-11-18 Aphton Corp. Immunogens against gonadotropin releasing hormone
FI97304C (fi) * 1994-11-16 1996-11-25 Locus Genex Oy Menetelmä mahasyövän riskin seulonnaksi
US6359114B1 (en) * 1995-06-07 2002-03-19 Aphton Corp. System for method for the modification and purification of proteins
ATE505202T1 (de) * 1996-02-08 2011-04-15 Cancer Advances Inc Immunologische methoden zur behandlung von gastrointestinalem krebs
ES2227833T3 (es) * 1997-05-12 2005-04-01 Aphton Corporation Composiciones inmunogenicas para el receptor cck-b/gastrina y metodos para el tratamiento de tumores.
AU768027B2 (en) * 1999-02-24 2003-11-27 Uab Research Foundation, The Taxane derivatives for targeted therapy of cancer

Also Published As

Publication number Publication date
JP5200251B2 (ja) 2013-06-05
EP0889735A1 (de) 1999-01-13
EP0889735B1 (de) 2011-04-13
US20050025770A1 (en) 2005-02-03
JP2007126461A (ja) 2007-05-24
DE69740173D1 (de) 2011-05-26
JP2012097062A (ja) 2012-05-24
PT889735E (pt) 2011-07-19
ES2361474T3 (es) 2011-06-17
JP5200269B2 (ja) 2013-06-05
DK0889735T3 (da) 2011-08-08
WO1997028821A1 (en) 1997-08-14
JP2000504692A (ja) 2000-04-18

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