DK0889735T3 - Immunogene metoder til behandling af gastrointestinal cancer - Google Patents
Immunogene metoder til behandling af gastrointestinal cancerInfo
- Publication number
- DK0889735T3 DK0889735T3 DK97905858.3T DK97905858T DK0889735T3 DK 0889735 T3 DK0889735 T3 DK 0889735T3 DK 97905858 T DK97905858 T DK 97905858T DK 0889735 T3 DK0889735 T3 DK 0889735T3
- Authority
- DK
- Denmark
- Prior art keywords
- treatment
- gastrointestinal cancer
- gastrin
- immunogenic methods
- immunogenic
- Prior art date
Links
- 206010017993 Gastrointestinal neoplasms Diseases 0.000 title abstract 2
- 230000002163 immunogen Effects 0.000 title 1
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 abstract 2
- 108010066264 gastrin 17 Proteins 0.000 abstract 2
- GKDWRERMBNGKCZ-RNXBIMIWSA-N gastrin-17 Chemical compound C([C@@H](C(=O)NCC(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC=1C2=CC=CC=C2NC=1)NC(=O)[C@H]1N(CCC1)C(=O)CNC(=O)[C@H]1NC(=O)CC1)C1=CC=C(O)C=C1 GKDWRERMBNGKCZ-RNXBIMIWSA-N 0.000 abstract 2
- 102400000921 Gastrin Human genes 0.000 abstract 1
- 239000004471 Glycine Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 108010063604 gastrin immunogen Proteins 0.000 abstract 1
- 108010017400 glycine-extended gastrin 17 Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/595—Gastrins; Cholecystokinins [CCK]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1141196P | 1996-02-08 | 1996-02-08 | |
| PCT/US1997/002029 WO1997028821A1 (en) | 1996-02-08 | 1997-02-07 | Immunological methods for the treatment of gastrointestinal cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0889735T3 true DK0889735T3 (da) | 2011-08-08 |
Family
ID=21750270
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK97905858.3T DK0889735T3 (da) | 1996-02-08 | 1997-02-07 | Immunogene metoder til behandling af gastrointestinal cancer |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20050025770A1 (da) |
| EP (1) | EP0889735B1 (da) |
| JP (3) | JP2000504692A (da) |
| AT (1) | ATE505202T1 (da) |
| DE (1) | DE69740173D1 (da) |
| DK (1) | DK0889735T3 (da) |
| ES (1) | ES2361474T3 (da) |
| PT (1) | PT889735E (da) |
| WO (1) | WO1997028821A1 (da) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997028821A1 (en) * | 1996-02-08 | 1997-08-14 | Aphton Corp. | Immunological methods for the treatment of gastrointestinal cancer |
| DE69827621T9 (de) * | 1997-05-12 | 2007-06-06 | Aphton Corp., Woodland | Immunogene zusammensetzungen gegen den cck-b-gastrin-rezeptor und verfahren zur behandlung von tumoren |
| US20040001842A1 (en) * | 1997-05-12 | 2004-01-01 | Dov Michaeli | Immunogenic compositions to the CCK-B/gastrin receptor and methods for the treatment of tumors |
| EP1897556A1 (en) * | 1998-05-15 | 2008-03-12 | Receptor Biologix, Inc. | Prevention and treatment of hypergastrinemia |
| CA2328501A1 (en) * | 1998-05-15 | 1999-11-25 | Aphton Corporation | Prevention and treatment of hypergastrinemia |
| US20030068326A1 (en) * | 1998-05-15 | 2003-04-10 | Aphton Corporation | Method for the treatment of gastroesophageal reflux disease |
| US20030091574A1 (en) * | 2001-03-23 | 2003-05-15 | Gevas Philip C. | Combination treatment of pancreatic cancer |
| US20090191232A1 (en) * | 2001-05-04 | 2009-07-30 | Gevas Philip C | Combination therapy for the treatment of tumors |
| WO2003005955A2 (en) * | 2001-07-09 | 2003-01-23 | Aphton Corporation | Treatment and prevention of cancerous and pre-cancerous conditions of the liver, lung and esophagus |
| US20050169979A1 (en) * | 2002-07-03 | 2005-08-04 | Dov Michaeli | Liposomal vaccine |
| CA2520010C (en) | 2003-03-28 | 2012-07-10 | Aphton Corporation | Gastrin hormone immunoassays |
| JP5576592B2 (ja) * | 2004-03-29 | 2014-08-20 | キャンサー アドヴァンシズ インコーポレイテッド | ガストリンホルモンに対するモノクローナル抗体 |
| ES2400058T3 (es) | 2004-09-22 | 2013-04-05 | Cancer Advances, Inc. | Anticuerpos monoclonales para progastrina |
| JP5558660B2 (ja) | 2007-05-11 | 2014-07-23 | 日東電工株式会社 | 両面接着性感圧接着シート |
| CN101797382B (zh) | 2010-03-03 | 2013-11-20 | 戚胜美 | 抗人前胃液素多肽免疫组合物 |
| US8674064B2 (en) * | 2010-03-03 | 2014-03-18 | Onkologix Ltd | Immunogenic compositions against human progastrin peptides |
| BR112015028429A2 (pt) * | 2013-05-21 | 2017-09-19 | Tyg Oncology Ltd | Composição imunogênica baseada em um imunógeno do peptídeo gastrina-17, uma vacina compreendendo a composição imunogênica, um kit para preparação da composição imunogênica, e sua utilização médica no tratamento de doenças gastrina dependentes |
| JP6525909B2 (ja) | 2016-03-15 | 2019-06-05 | 中外炉工業株式会社 | 工業炉 |
| WO2018232230A1 (en) | 2017-06-15 | 2018-12-20 | Cancer Advances Inc. | Compositions and methods for inducing humoral and cellular immunities against tumors and cancer |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US140962A (en) * | 1873-07-15 | Improvement in feeding paper to printing-presses | ||
| US69966A (en) * | 1867-10-22 | Joseph chadwick | ||
| US20119A (en) * | 1858-04-27 | Improvement in raking and delivering attachments to harvesters | ||
| US21786A (en) * | 1858-10-12 | Improvement in the manufacture of sugar | ||
| US1842A (en) * | 1840-10-31 | Machine fob cutting corks | ||
| US187152A (en) * | 1877-02-06 | Improvement in clothes-wringers | ||
| US58040A (en) * | 1866-09-18 | Improvement in making bolts | ||
| US91574A (en) * | 1869-06-22 | Improvement in water-closet valves | ||
| US39911A (en) * | 1863-09-15 | Improvement in corset skirt-supporters | ||
| US95028A (en) * | 1869-09-21 | Improved process for preserving eggs | ||
| US68326A (en) * | 1867-08-27 | Alcibiades j | ||
| US86941A (en) * | 1869-02-16 | Improvement in corn-planter | ||
| US4526716A (en) * | 1981-11-20 | 1985-07-02 | The Ohio State University | Antigenic modification of polypeptides |
| US4691006A (en) * | 1983-03-04 | 1987-09-01 | Ohio State University | Antigenic modification of polypeptides |
| US4384995A (en) * | 1980-01-16 | 1983-05-24 | The Ohio State University | Antigenic modification of polypeptides |
| IT1179894B (it) * | 1984-12-27 | 1987-09-16 | Rotta Research Lab | Proglumide e composizioni farmaceutiche che la contengono per l impiego nella terapia di affezioni neoplastiche |
| US6861510B1 (en) * | 1989-01-24 | 2005-03-01 | Aphton Corporation | Immunogenic compositions against gastrin peptides |
| ES2063912T3 (es) * | 1989-01-24 | 1995-01-16 | Aphton Corp | Composiciones inmunogenicas frente a peptidos de gastrina. |
| US5023077A (en) * | 1989-01-24 | 1991-06-11 | Aphton Corporation | Immunogenic compositions and methods for the treatment and prevention of gastric and duodenal ulcer disease |
| US5319073A (en) * | 1992-02-07 | 1994-06-07 | The United States Of America, As Represented By The Department Of Health & Human Services | Method of purifying cholecystokinin receptor protein |
| US5759551A (en) * | 1993-04-27 | 1998-06-02 | United Biomedical, Inc. | Immunogenic LHRH peptide constructs and synthetic universal immune stimulators for vaccines |
| US5468494A (en) | 1993-11-12 | 1995-11-21 | Aphton Corp. | Immunogenic compositions against human gastrin 17 |
| US5688506A (en) * | 1994-01-27 | 1997-11-18 | Aphton Corp. | Immunogens against gonadotropin releasing hormone |
| FI97304C (fi) * | 1994-11-16 | 1996-11-25 | Locus Genex Oy | Menetelmä mahasyövän riskin seulonnaksi |
| US6359114B1 (en) * | 1995-06-07 | 2002-03-19 | Aphton Corp. | System for method for the modification and purification of proteins |
| WO1997028821A1 (en) * | 1996-02-08 | 1997-08-14 | Aphton Corp. | Immunological methods for the treatment of gastrointestinal cancer |
| DE69827621T9 (de) * | 1997-05-12 | 2007-06-06 | Aphton Corp., Woodland | Immunogene zusammensetzungen gegen den cck-b-gastrin-rezeptor und verfahren zur behandlung von tumoren |
| CA2362937C (en) * | 1999-02-24 | 2011-03-22 | The Uab Research Foundation | Taxane derivatives for targeted therapy of cancer |
-
1997
- 1997-02-07 WO PCT/US1997/002029 patent/WO1997028821A1/en active Application Filing
- 1997-02-07 PT PT97905858T patent/PT889735E/pt unknown
- 1997-02-07 AT AT97905858T patent/ATE505202T1/de active
- 1997-02-07 JP JP9528702A patent/JP2000504692A/ja not_active Withdrawn
- 1997-02-07 EP EP97905858A patent/EP0889735B1/en not_active Expired - Lifetime
- 1997-02-07 DK DK97905858.3T patent/DK0889735T3/da active
- 1997-02-07 DE DE69740173T patent/DE69740173D1/de not_active Expired - Lifetime
- 1997-02-07 ES ES97905858T patent/ES2361474T3/es not_active Expired - Lifetime
-
2004
- 2004-01-20 US US10/762,226 patent/US20050025770A1/en not_active Abandoned
-
2006
- 2006-11-16 JP JP2006310647A patent/JP5200251B2/ja not_active Expired - Lifetime
-
2011
- 2011-02-21 JP JP2011034753A patent/JP5200269B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| PT889735E (pt) | 2011-07-19 |
| JP2007126461A (ja) | 2007-05-24 |
| DE69740173D1 (de) | 2011-05-26 |
| WO1997028821A1 (en) | 1997-08-14 |
| EP0889735A1 (en) | 1999-01-13 |
| US20050025770A1 (en) | 2005-02-03 |
| ES2361474T3 (es) | 2011-06-17 |
| JP2012097062A (ja) | 2012-05-24 |
| JP5200251B2 (ja) | 2013-06-05 |
| ATE505202T1 (de) | 2011-04-15 |
| EP0889735B1 (en) | 2011-04-13 |
| JP5200269B2 (ja) | 2013-06-05 |
| JP2000504692A (ja) | 2000-04-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0889735T3 (da) | Immunogene metoder til behandling af gastrointestinal cancer | |
| WO1997028821B1 (en) | Immunological methods for the treatment of gastrointestinal cancer | |
| NO983999D0 (no) | Peptidimmunogener for vaksinasjon mot og behandling av allergi | |
| IL139700A0 (en) | Immunotherapeutic composition and method for the treatment of prostate cancer | |
| BR9811264A (pt) | Composições imunogênicas ao receptor de gastrina/cck-b e métodos para o tratamento de tumores | |
| DK442788D0 (da) | Fremgangsmaade og praeparat til behandling af non-ige-medierede lidelser | |
| GR3030141T3 (en) | Diphtheria toxin receptor-binding region. | |
| PL332742A1 (en) | Transformed human antibody against hm 1.24 | |
| BR9912177A (pt) | Epìtopos de célula auxiliar t artificiais como imunoestimuladores para imunógenos de peptìdeo sintéticos | |
| ZA945364B (en) | Antibodies specific for human prostate glandular kallikrein | |
| EP0380230A3 (en) | Immunogenic compositions against gastrin peptides | |
| IL126803A0 (en) | Method and composition for reconforming multi-epitopic antigens to initiate an immune response | |
| IL165398A0 (en) | Method for identifying immunoreactive peptides | |
| WO1996021734A3 (en) | P15 and tyrosinase melanoma antigens and their use in diagnostic and therapeutic methods | |
| PL338449A1 (en) | Ligands, including antibodies, exhibiting reactivity in respect to endocrine secretion cells | |
| WO2000069915A3 (en) | COMBINED APPROACH TO TREATMENT OF CANCER WITH hCG VACCINES | |
| GB9509620D0 (en) | Transepithelial transport of molecular species | |
| DE69626642T2 (de) | Cetp zur erhöhung des hdl-cholesterol-gehalts | |
| EP0734451A4 (en) | ENTEROTOXINS OF -i (SHIGELLA FLEXNERI) 2a | |
| ATE286914T1 (de) | Verwendung von blockierenden anti-tsh-rezeptor- antikörpern bei der therapie von hyperthyreosen sowie monoklonale antikörper für eine solche verwendung | |
| HU9300928D0 (en) | Endothelial-leucocyta adhesion molecule-1 (elam-1) and its antibodies being applicable for treatment of asthma | |
| UA22181A (uk) | Спосіб лікуваhhя гіпогалактії |