IL67564A - 7-heteroaryl-(1,2)-fused 1,4-benzodiazepine compounds,their preparation and pharmaceutical compositions containing them - Google Patents

7-heteroaryl-(1,2)-fused 1,4-benzodiazepine compounds,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL67564A
IL67564A IL67564A IL6756482A IL67564A IL 67564 A IL67564 A IL 67564A IL 67564 A IL67564 A IL 67564A IL 6756482 A IL6756482 A IL 6756482A IL 67564 A IL67564 A IL 67564A
Authority
IL
Israel
Prior art keywords
radical
compounds
hydrogen
fused
atom
Prior art date
Application number
IL67564A
Other languages
English (en)
Other versions
IL67564A0 (en
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of IL67564A0 publication Critical patent/IL67564A0/xx
Publication of IL67564A publication Critical patent/IL67564A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
IL67564A 1981-12-28 1982-12-27 7-heteroaryl-(1,2)-fused 1,4-benzodiazepine compounds,their preparation and pharmaceutical compositions containing them IL67564A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813151597 DE3151597A1 (de) 1981-12-28 1981-12-28 (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
IL67564A0 IL67564A0 (en) 1983-05-15
IL67564A true IL67564A (en) 1986-10-31

Family

ID=6149862

Family Applications (1)

Application Number Title Priority Date Filing Date
IL67564A IL67564A (en) 1981-12-28 1982-12-27 7-heteroaryl-(1,2)-fused 1,4-benzodiazepine compounds,their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (2) US4508716A (da)
EP (1) EP0084155B1 (da)
JP (1) JPS58118590A (da)
AT (1) ATE26116T1 (da)
AU (1) AU555893B2 (da)
CA (1) CA1194474A (da)
DD (1) DD208807A5 (da)
DE (2) DE3151597A1 (da)
DK (1) DK574582A (da)
ES (1) ES8308565A1 (da)
FI (1) FI73684C (da)
GR (1) GR78408B (da)
HU (1) HU186207B (da)
IL (1) IL67564A (da)
NO (1) NO158462C (da)
NZ (1) NZ202902A (da)
PH (1) PH19310A (da)
PT (1) PT75966B (da)
SU (1) SU1331431A3 (da)
ZA (1) ZA829526B (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151597A1 (de) * 1981-12-28 1983-07-07 Kali-Chemie Pharma Gmbh, 3000 Hannover (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4596799A (en) * 1985-01-29 1986-06-24 Ciba-Geigy Corporation 9H-pyrrolo[2,1-c]-1,2,4-triazolo[4,3-a][1,4]benzodiazepines
US4882323A (en) * 1988-02-23 1989-11-21 American Home Products 1,2,3,4,5,6-hexahydro[1,3,6]triazocino[1,1-a]benzimidazoles
FI99271C (fi) * 1996-04-12 1998-02-25 Valmet Corp Menetelmä ja sovitelma kuiturainan kuivatuslaitteen energian hyödyntämiseksi

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182067A (en) * 1964-04-09 1965-05-04 Hoffmann La Roche Benzodiazepine compounds
BE790839A (fr) * 1971-11-02 1973-04-30 Upjohn Co Nouvelles benzodiazepines, leur procede de preparation et medicament les contenant
DE2265371C3 (de) * 1972-05-03 1980-12-11 Kali-Chemie Ag, 3000 Hannover N-(3-Benzoylaminopropyl)-aniline
DE2314993A1 (de) * 1973-03-26 1974-10-03 Kali Chemie Pharma Gmbh Neue benzodiazepinderivate und verfahren zu deren herstellung
US3933816A (en) * 1974-09-12 1976-01-20 The Upjohn Company 3-(Substituted aminomethyl)-7-substituted-3,5-dihydro-as-triazino[4,3-a][1,5]benzodiazepines
US4073784A (en) * 1977-03-09 1978-02-14 The Upjohn Company Certain as-triazino 4,3-a! 1,4!benzodiazepine-1,2-dione compounds
DE2835708A1 (de) * 1978-08-16 1980-03-06 Kali Chemie Pharma Gmbh Neue eckige klammer auf 1,2 eckige klammer zu-anellierte 7-phenyl-1,4-benzodiazepinderivate, verfahren zu deren herstellung und arzneimittel
DE2952279A1 (de) * 1979-12-24 1981-06-25 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3151597A1 (de) * 1981-12-28 1983-07-07 Kali-Chemie Pharma Gmbh, 3000 Hannover (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
NO158462C (no) 1988-09-14
US4508716A (en) 1985-04-02
FI824479A0 (fi) 1982-12-27
FI73684B (fi) 1987-07-31
NZ202902A (en) 1985-07-12
JPS58118590A (ja) 1983-07-14
DD208807A5 (de) 1984-04-11
PT75966B (en) 1985-10-04
SU1331431A3 (ru) 1987-08-15
DK574582A (da) 1983-06-29
PT75966A (en) 1983-01-01
FI824479L (fi) 1983-06-29
NO824379L (no) 1983-06-29
EP0084155B1 (de) 1987-03-25
EP0084155A3 (en) 1984-07-25
EP0084155A2 (de) 1983-07-27
DE3275830D1 (en) 1987-04-30
AU9192782A (en) 1983-07-07
HU186207B (en) 1985-06-28
PH19310A (en) 1986-03-14
ES518573A0 (es) 1983-09-01
CA1194474A (en) 1985-10-01
ZA829526B (en) 1983-10-26
ES8308565A1 (es) 1983-09-01
ATE26116T1 (de) 1987-04-15
AU555893B2 (en) 1986-10-16
US4594436A (en) 1986-06-10
FI73684C (fi) 1987-11-09
NO158462B (no) 1988-06-06
IL67564A0 (en) 1983-05-15
DE3151597A1 (de) 1983-07-07
GR78408B (da) 1984-09-27

Similar Documents

Publication Publication Date Title
ATE74352T1 (de) Dekahydrochinolinderivate, verfahren zu ihrer herstellung, zwischenprodukte zu ihrer herstellung, ihre verwendung als arzneimittel und diese enthaltende zubereitungen.
DE3170937D1 (en) 2-(1,4-benzodioxan-2-ylalkyl) imidazoles, their preparation and pharmaceutical compositions containing them
NZ214289A (en) Derivatives of 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin -3-one compounds, preparation and pharmaceutical compositions
ES481551A1 (es) Procedimiento de preparacion de nuevos compuestos bis (ari- loxicarboxilicos).
IL67564A (en) 7-heteroaryl-(1,2)-fused 1,4-benzodiazepine compounds,their preparation and pharmaceutical compositions containing them
PT77208B (de) Neue thieno-thieno-derivate verfahren zu ihrer herstellung und diese verbindugen enthaltende
GR3020292T3 (en) Use of 2-iminothiazolidin-4-one derivatives as new medicaments
DE3365933D1 (en) Substituted thienobenzodiazepinones, process for their preparation and medicines containing these compounds
ATE43594T1 (de) 3-alkoxy-2-(n-pyrrolidino)-n-pyridyl-n-furyl(od r thienyl)-methyl-propylamine, ihre herstellung und diese enthaltende pharmazeutische mittel.
ES8406456A1 (es) Procedimiento de preparacion de derivados de piperacina
DE3160719D1 (en) Benzothiopyrano(2,3-c) pyridines and their acid addition salts, their preparation, their use as medicaments and compositions containing them
DE3361834D1 (en) Dithiino (1,4) (2,3-c) pyrrole derivatives, their preparation and pharmaceutical compositions containing them
ES8403471A1 (es) Un procedimiento para preparar nuevos compuestos de cromanona.