NO158462C - Analogifremgangsmaate for fremstilling av terapeutisk aktive (1,2)-kondenserte 1,4-benzodiazepinforbindelser. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive (1,2)-kondenserte 1,4-benzodiazepinforbindelser.

Info

Publication number
NO158462C
NO158462C NO824379A NO824379A NO158462C NO 158462 C NO158462 C NO 158462C NO 824379 A NO824379 A NO 824379A NO 824379 A NO824379 A NO 824379A NO 158462 C NO158462 C NO 158462C
Authority
NO
Norway
Prior art keywords
radical
compounds
hydrogen
atom
condensed
Prior art date
Application number
NO824379A
Other languages
English (en)
Other versions
NO158462B (no
NO824379L (no
Inventor
Hans Liepmann
Michael Ruhland
Herbert Muesch
Werner Benson
Henning Heinemann
Horst Zeugner
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of NO824379L publication Critical patent/NO824379L/no
Publication of NO158462B publication Critical patent/NO158462B/no
Publication of NO158462C publication Critical patent/NO158462C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/14Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO824379A 1981-12-28 1982-12-27 Analogifremgangsmaate for fremstilling av terapeutisk aktive (1,2)-kondenserte 1,4-benzodiazepinforbindelser. NO158462C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19813151597 DE3151597A1 (de) 1981-12-28 1981-12-28 (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (3)

Publication Number Publication Date
NO824379L NO824379L (no) 1983-06-29
NO158462B NO158462B (no) 1988-06-06
NO158462C true NO158462C (no) 1988-09-14

Family

ID=6149862

Family Applications (1)

Application Number Title Priority Date Filing Date
NO824379A NO158462C (no) 1981-12-28 1982-12-27 Analogifremgangsmaate for fremstilling av terapeutisk aktive (1,2)-kondenserte 1,4-benzodiazepinforbindelser.

Country Status (20)

Country Link
US (2) US4508716A (no)
EP (1) EP0084155B1 (no)
JP (1) JPS58118590A (no)
AT (1) ATE26116T1 (no)
AU (1) AU555893B2 (no)
CA (1) CA1194474A (no)
DD (1) DD208807A5 (no)
DE (2) DE3151597A1 (no)
DK (1) DK574582A (no)
ES (1) ES8308565A1 (no)
FI (1) FI73684C (no)
GR (1) GR78408B (no)
HU (1) HU186207B (no)
IL (1) IL67564A (no)
NO (1) NO158462C (no)
NZ (1) NZ202902A (no)
PH (1) PH19310A (no)
PT (1) PT75966B (no)
SU (1) SU1331431A3 (no)
ZA (1) ZA829526B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3151597A1 (de) * 1981-12-28 1983-07-07 Kali-Chemie Pharma Gmbh, 3000 Hannover (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4596799A (en) * 1985-01-29 1986-06-24 Ciba-Geigy Corporation 9H-pyrrolo[2,1-c]-1,2,4-triazolo[4,3-a][1,4]benzodiazepines
US4882323A (en) * 1988-02-23 1989-11-21 American Home Products 1,2,3,4,5,6-hexahydro[1,3,6]triazocino[1,1-a]benzimidazoles
FI99271C (fi) * 1996-04-12 1998-02-25 Valmet Corp Menetelmä ja sovitelma kuiturainan kuivatuslaitteen energian hyödyntämiseksi

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3182067A (en) * 1964-04-09 1965-05-04 Hoffmann La Roche Benzodiazepine compounds
BE790839A (fr) * 1971-11-02 1973-04-30 Upjohn Co Nouvelles benzodiazepines, leur procede de preparation et medicament les contenant
DE2221558C2 (de) * 1972-05-03 1982-12-02 Kali-Chemie Ag, 3000 Hannover 5-Phenyl-2,3-dihydro-1H-1,4-benzodiazepine und ihre Säureadditionssalze, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2314993A1 (de) * 1973-03-26 1974-10-03 Kali Chemie Pharma Gmbh Neue benzodiazepinderivate und verfahren zu deren herstellung
US3933816A (en) * 1974-09-12 1976-01-20 The Upjohn Company 3-(Substituted aminomethyl)-7-substituted-3,5-dihydro-as-triazino[4,3-a][1,5]benzodiazepines
US4073784A (en) * 1977-03-09 1978-02-14 The Upjohn Company Certain as-triazino 4,3-a! 1,4!benzodiazepine-1,2-dione compounds
DE2835708A1 (de) * 1978-08-16 1980-03-06 Kali Chemie Pharma Gmbh Neue eckige klammer auf 1,2 eckige klammer zu-anellierte 7-phenyl-1,4-benzodiazepinderivate, verfahren zu deren herstellung und arzneimittel
DE2952279A1 (de) * 1979-12-24 1981-06-25 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue 2-acylaminomethyl-1,4-benzodiazepine und deren salze sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3151597A1 (de) * 1981-12-28 1983-07-07 Kali-Chemie Pharma Gmbh, 3000 Hannover (1,2)-anellierte 1,4-benzodiazepin-verbindungen sowie verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
JPS58118590A (ja) 1983-07-14
ATE26116T1 (de) 1987-04-15
GR78408B (no) 1984-09-27
NZ202902A (en) 1985-07-12
DE3275830D1 (en) 1987-04-30
FI824479A0 (fi) 1982-12-27
FI73684B (fi) 1987-07-31
EP0084155A3 (en) 1984-07-25
FI73684C (fi) 1987-11-09
DK574582A (da) 1983-06-29
IL67564A0 (en) 1983-05-15
DD208807A5 (de) 1984-04-11
US4594436A (en) 1986-06-10
SU1331431A3 (ru) 1987-08-15
NO158462B (no) 1988-06-06
AU555893B2 (en) 1986-10-16
NO824379L (no) 1983-06-29
ES518573A0 (es) 1983-09-01
EP0084155B1 (de) 1987-03-25
PH19310A (en) 1986-03-14
ES8308565A1 (es) 1983-09-01
ZA829526B (en) 1983-10-26
US4508716A (en) 1985-04-02
EP0084155A2 (de) 1983-07-27
IL67564A (en) 1986-10-31
DE3151597A1 (de) 1983-07-07
PT75966A (en) 1983-01-01
FI824479L (fi) 1983-06-29
AU9192782A (en) 1983-07-07
PT75966B (en) 1985-10-04
HU186207B (en) 1985-06-28
CA1194474A (en) 1985-10-01

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