IL64902A0 - Carbacyclin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same - Google Patents
Carbacyclin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the sameInfo
- Publication number
- IL64902A0 IL64902A0 IL64902A IL6490282A IL64902A0 IL 64902 A0 IL64902 A0 IL 64902A0 IL 64902 A IL64902 A IL 64902A IL 6490282 A IL6490282 A IL 6490282A IL 64902 A0 IL64902 A0 IL 64902A0
- Authority
- IL
- Israel
- Prior art keywords
- group
- carbon atoms
- see diagramm
- alkyl
- hydrogen
- Prior art date
Links
- XZFRIPGNUQRGPI-WLPVIMDJSA-N Carbacyclin Chemical class C1\C(=C\CCCC(O)=O)C[C@@H]2[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C[C@@H]21 XZFRIPGNUQRGPI-WLPVIMDJSA-N 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 9
- 125000000217 alkyl group Chemical group 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 6
- -1 hydroxymethylene group Chemical group 0.000 abstract 4
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 3
- 150000003839 salts Chemical group 0.000 abstract 3
- 101100294106 Caenorhabditis elegans nhr-3 gene Proteins 0.000 abstract 2
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 abstract 2
- 125000002947 alkylene group Chemical group 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 125000004170 methylsulfonyl group Chemical group [H]C([H])([H])S(*)(=O)=O 0.000 abstract 2
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052744 lithium Inorganic materials 0.000 abstract 1
- 125000004665 trialkylsilyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyrane Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813104044 DE3104044A1 (de) | 1981-02-02 | 1981-02-02 | Neue prostacyclin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IL64902A0 true IL64902A0 (en) | 1982-03-31 |
Family
ID=6124154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL64902A IL64902A0 (en) | 1981-02-02 | 1982-01-31 | Carbacyclin derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0057660B1 (ja) |
| JP (1) | JPS57176924A (ja) |
| AT (1) | ATE15029T1 (ja) |
| AU (1) | AU7995782A (ja) |
| DD (1) | DD201884A5 (ja) |
| DE (2) | DE3104044A1 (ja) |
| DK (1) | DK43482A (ja) |
| ES (1) | ES8301912A1 (ja) |
| FI (1) | FI820327L (ja) |
| GR (1) | GR74746B (ja) |
| IE (1) | IE820228L (ja) |
| IL (1) | IL64902A0 (ja) |
| NO (1) | NO820298L (ja) |
| ZA (1) | ZA82670B (ja) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3237200A1 (de) * | 1982-10-05 | 1984-04-05 | Schering AG, 1000 Berlin und 4709 Bergkamen | 5-fluorcarbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3204443A1 (de) * | 1982-02-08 | 1983-08-18 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3221193A1 (de) * | 1982-05-28 | 1983-12-01 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacyclinester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS59141536A (ja) * | 1983-02-01 | 1984-08-14 | Sumitomo Chem Co Ltd | 新規ビシクロオクタン誘導体 |
| JPS60172941A (ja) * | 1984-02-16 | 1985-09-06 | Sankyo Co Ltd | カルバサイクリン類 |
| JPS60181041A (ja) * | 1984-02-29 | 1985-09-14 | Sankyo Co Ltd | カルバサイクリン誘導体 |
| ATE306256T1 (de) * | 1999-08-05 | 2005-10-15 | Teijin Ltd | Mittel zur besserung der neuropathie, die als wirkstoff stickstoffhaltige verbindungen enthalten |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4705806A (en) * | 1978-02-13 | 1987-11-10 | Morton Jr Douglas R | Prostacyclin analogs |
| DE2845770A1 (de) * | 1978-10-19 | 1980-04-30 | Schering Ag | Neue prostacyclin-derivate und verfahren zu ihrer herstellung |
-
1981
- 1981-02-02 DE DE19813104044 patent/DE3104044A1/de not_active Withdrawn
-
1982
- 1982-01-29 AU AU79957/82A patent/AU7995782A/en not_active Abandoned
- 1982-01-31 IL IL64902A patent/IL64902A0/xx unknown
- 1982-02-01 DD DD82237116A patent/DD201884A5/de unknown
- 1982-02-01 DK DK43482A patent/DK43482A/da not_active Application Discontinuation
- 1982-02-01 EP EP82730008A patent/EP0057660B1/de not_active Expired
- 1982-02-01 GR GR67166A patent/GR74746B/el unknown
- 1982-02-01 AT AT82730008T patent/ATE15029T1/de not_active IP Right Cessation
- 1982-02-01 DE DE8282730008T patent/DE3265495D1/de not_active Expired
- 1982-02-01 NO NO820298A patent/NO820298L/no unknown
- 1982-02-02 ES ES509265A patent/ES8301912A1/es not_active Expired
- 1982-02-02 JP JP57014399A patent/JPS57176924A/ja active Granted
- 1982-02-02 IE IE820228A patent/IE820228L/xx unknown
- 1982-02-02 FI FI820327A patent/FI820327L/fi not_active Application Discontinuation
- 1982-02-02 ZA ZA82670A patent/ZA82670B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES509265A0 (es) | 1983-01-16 |
| EP0057660A2 (de) | 1982-08-11 |
| FI820327L (fi) | 1982-08-03 |
| GR74746B (ja) | 1984-07-11 |
| NO820298L (no) | 1982-08-03 |
| AU7995782A (en) | 1982-08-12 |
| DD201884A5 (de) | 1983-08-17 |
| DE3104044A1 (de) | 1982-08-26 |
| ZA82670B (en) | 1982-12-29 |
| JPH0451537B2 (ja) | 1992-08-19 |
| EP0057660A3 (en) | 1982-09-01 |
| EP0057660B1 (de) | 1985-08-21 |
| ES8301912A1 (es) | 1983-01-16 |
| DK43482A (da) | 1982-08-03 |
| JPS57176924A (en) | 1982-10-30 |
| IE820228L (en) | 1982-08-02 |
| ATE15029T1 (de) | 1985-09-15 |
| DE3265495D1 (en) | 1985-09-26 |
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