IL64798A - Stabilized dilute aqueous preparation of 1alpha,25-dihydroxycholecalciferol and process for its preparation - Google Patents
Stabilized dilute aqueous preparation of 1alpha,25-dihydroxycholecalciferol and process for its preparationInfo
- Publication number
- IL64798A IL64798A IL64798A IL6479882A IL64798A IL 64798 A IL64798 A IL 64798A IL 64798 A IL64798 A IL 64798A IL 6479882 A IL6479882 A IL 6479882A IL 64798 A IL64798 A IL 64798A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- dihydroxycholecalciferol
- 1alpha
- dilute aqueous
- stabilized
- Prior art date
Links
- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 title 1
- 235000020964 calcitriol Nutrition 0.000 title 1
- 239000011612 calcitriol Substances 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Nutrition Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/228,870 US4308264A (en) | 1981-01-28 | 1981-01-28 | Stabilized, dilute aqueous preparation of 1α,25-dihydroxycholecalciferol for neonatal administration |
Publications (2)
Publication Number | Publication Date |
---|---|
IL64798A0 IL64798A0 (en) | 1982-03-31 |
IL64798A true IL64798A (en) | 1984-11-30 |
Family
ID=22858867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL64798A IL64798A (en) | 1981-01-28 | 1982-01-18 | Stabilized dilute aqueous preparation of 1alpha,25-dihydroxycholecalciferol and process for its preparation |
Country Status (10)
Country | Link |
---|---|
US (1) | US4308264A (fr) |
JP (1) | JPS57144218A (fr) |
AU (1) | AU549765B2 (fr) |
CA (1) | CA1174605A (fr) |
CH (1) | CH651208A5 (fr) |
DE (1) | DE3202622A1 (fr) |
FR (1) | FR2498450A1 (fr) |
GB (1) | GB2091556B (fr) |
IL (1) | IL64798A (fr) |
NZ (1) | NZ199472A (fr) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4308264A (en) * | 1981-01-28 | 1981-12-29 | Abbott Laboratories | Stabilized, dilute aqueous preparation of 1α,25-dihydroxycholecalciferol for neonatal administration |
USRE33107E (en) * | 1983-03-22 | 1989-11-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
US4610978A (en) * | 1983-03-22 | 1986-09-09 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Compositions containing 1α-hydroxycholecalciferol for topical treatment of skin disorders and methods employing same |
CA1272953A (fr) * | 1984-10-08 | 1990-08-21 | Yuji Makino | Compose pharmaceutique pour usage externe contenant de la vitasmine d.sub.3 de type acitf |
JPS62149619A (ja) * | 1985-09-05 | 1987-07-03 | Teijin Ltd | 活性型ビタミンd3類注射用組成物 |
WO1990003173A1 (fr) | 1988-09-26 | 1990-04-05 | Teijin Limited | Preparation aqueuse stable a base de vitamine d3 active |
JP2525478B2 (ja) * | 1989-03-01 | 1996-08-21 | 帝人株式会社 | 安定性の改良された活性型ビタミンd▲下3▼類固型製剤 |
US5258375A (en) * | 1989-03-13 | 1993-11-02 | Ss Pharmaceutical Co., Ltd. | Composition for the preparation of dosage-form active vitamins D3 containing polyvinylacetal diethylaminoacetate |
TW284788B (fr) * | 1991-05-28 | 1996-09-01 | L Air Liquide Soliete And Nyme Dour L Expl Des Proce | |
JP3193494B2 (ja) * | 1992-01-03 | 2001-07-30 | レール・リキード・ソシエテ・アノニム・プール・レテュード・エ・レクスプロワタシオン・デ・プロセデ・ジョルジュ・クロード | 希ガスを使用し、グルコースから高フルクトースコーンシロップを製造する方法 |
US6342261B1 (en) | 1992-04-03 | 2002-01-29 | American Air Liquide | Method of preserving foods using noble gases |
WO1993019628A1 (fr) | 1992-04-03 | 1993-10-14 | L'air Liquide, Societe Anonyme Pour L'etude Et L'exploitation Des Procedes Georges Claude | Procede de maitrise des reactions de brunissage mettant en ×uvre des gaz nobles |
US5364777A (en) * | 1992-04-03 | 1994-11-15 | American Air Liquide | Method of improving lipase activity using noble gases |
US5328823A (en) * | 1992-11-27 | 1994-07-12 | American Air Liquide | Enzyme-based biosensors for detecting noble gases |
US5382525A (en) * | 1992-11-27 | 1995-01-17 | American Air Liquide | Method of effecting increased performance of diagnostic enzyme reaction systems using noble gases |
CA2109458A1 (fr) | 1992-11-27 | 1994-05-28 | Kevin C. Spencer | Methode d'amelioration de procedes a l'aide de pectinases et de gaz rares |
AU5861396A (en) * | 1995-05-19 | 1996-11-29 | Abbott Laboratories | Stable aqueous formulations of 1alpha,25-dihydroxycholecalci ferol for parenteral administration |
US6136799A (en) * | 1998-04-08 | 2000-10-24 | Abbott Laboratories | Cosolvent formulations |
US6051567A (en) * | 1999-08-02 | 2000-04-18 | Abbott Laboratories | Low oxygen content compositions of 1α, 25-dihydroxycholecalciferol |
US6274169B1 (en) * | 1999-08-02 | 2001-08-14 | Abbott Laboratories | Low oxygen content compostions of 1α, 25-dihydroxycholecalciferol |
US6211169B1 (en) * | 1999-09-29 | 2001-04-03 | Aesgen, Inc. | Stable calcitriol solution for packaging into vials |
US20010036937A1 (en) * | 2000-04-07 | 2001-11-01 | Leticia Delgado-Herrera | Treatment of ICU-associated hypocalcemia with vitamin D compounds |
US6887897B2 (en) | 2001-07-31 | 2005-05-03 | Mission Pharmacal Company | Calcium glutarate supplement and phosphorus binder |
IL162213A0 (en) * | 2001-12-03 | 2005-11-20 | Novacea Inc | Pharmaceutical compositions containing active vitamin d compounds |
JP4625637B2 (ja) | 2002-02-22 | 2011-02-02 | シャイア エルエルシー | 活性物質送達系及び活性物質を保護し投与する方法 |
US20040053895A1 (en) * | 2002-09-18 | 2004-03-18 | Bone Care International, Inc. | Multi-use vessels for vitamin D formulations |
US20040058895A1 (en) * | 2002-09-18 | 2004-03-25 | Bone Care International, Inc. | Multi-use vessels for vitamin D formulations |
US7148211B2 (en) * | 2002-09-18 | 2006-12-12 | Genzyme Corporation | Formulation for lipophilic agents |
WO2004087190A1 (fr) * | 2003-04-02 | 2004-10-14 | Genix Therapeutics Inc. | Procede de traitement du cancer de la prostate |
US20060189586A1 (en) * | 2003-06-11 | 2006-08-24 | Cleland Jeffrey L | Pharmaceutical compositions comprising active vitamin D compounds |
FR2871695B1 (fr) * | 2004-06-17 | 2008-07-04 | Galderma Sa | Composition pharmaceutique comprenant un agent silicone et deux principes actifs solubilises |
KR20070027587A (ko) * | 2004-06-17 | 2007-03-09 | 갈데르마 소시에떼아노님 | 실리콘제, 코르티코스테로이드 및 비타민 d 또는 이의유도체를 함유하는 건선 치료용 조성물 |
US20080293647A1 (en) | 2004-11-12 | 2008-11-27 | Luciano Adorini | Combined Use Of Vitamin D Derivatives And Anti-Proliferative Agents For Treating Bladder Cancer |
US20100075933A1 (en) * | 2008-07-28 | 2010-03-25 | Sunita Vijay Shelke | Injectable compositions of vitamin d compounds |
EP2289555A1 (fr) * | 2009-08-24 | 2011-03-02 | OrgaNext Research B.V. | Procédé de traitement des faiblesses |
CN103142534B (zh) * | 2013-03-21 | 2014-11-12 | 青岛正大海尔制药有限公司 | 骨化三醇控释片及其制备方法 |
CN103142536B (zh) * | 2013-03-21 | 2014-11-12 | 青岛正大海尔制药有限公司 | 骨化三醇肠溶片及其制备方法 |
CN103142537B (zh) * | 2013-03-21 | 2014-11-12 | 青岛正大海尔制药有限公司 | 骨化三醇缓释剂片 |
US10174362B2 (en) | 2017-01-16 | 2019-01-08 | Spectrum Solutions L.L.C. | Nucleic acid preservation solution and methods of manufacture and use |
CN108030767B (zh) * | 2017-12-29 | 2020-07-24 | 河南泰丰生物科技有限公司 | 一种骨化三醇注射液及其制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3149037A (en) * | 1962-09-07 | 1964-09-15 | Hoffmann La Roche | Vitamin compositions |
US3384545A (en) * | 1965-03-09 | 1968-05-21 | Hoffmann La Roche | Injectable aqueous emulsions of fat soluble vitamins |
DE2526938C2 (de) * | 1975-02-14 | 1982-04-22 | F. Hoffmann-La Roche & Co. AG, 4002 Basel | Vitaminpräparate |
JPS5452717A (en) * | 1977-09-29 | 1979-04-25 | Chugai Pharmaceut Co Ltd | Stable oily pharmaceuticals containing 1alpha-hydroxyvitamin d |
JPS55136229A (en) * | 1979-04-10 | 1980-10-23 | Teijin Ltd | Adjustment of bone metabolism in warm-blooded animal and drug for it |
US4308264A (en) * | 1981-01-28 | 1981-12-29 | Abbott Laboratories | Stabilized, dilute aqueous preparation of 1α,25-dihydroxycholecalciferol for neonatal administration |
-
1981
- 1981-01-28 US US06/228,870 patent/US4308264A/en not_active Expired - Lifetime
-
1982
- 1982-01-12 NZ NZ199472A patent/NZ199472A/en unknown
- 1982-01-13 CA CA000394022A patent/CA1174605A/fr not_active Expired
- 1982-01-18 IL IL64798A patent/IL64798A/xx unknown
- 1982-01-19 AU AU79613/82A patent/AU549765B2/en not_active Expired
- 1982-01-25 CH CH447/82A patent/CH651208A5/fr not_active IP Right Cessation
- 1982-01-25 GB GB8202054A patent/GB2091556B/en not_active Expired
- 1982-01-27 DE DE19823202622 patent/DE3202622A1/de active Granted
- 1982-01-27 FR FR8201259A patent/FR2498450A1/fr active Granted
- 1982-01-28 JP JP57011052A patent/JPS57144218A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
DE3202622A1 (de) | 1982-09-09 |
GB2091556A (en) | 1982-08-04 |
FR2498450B1 (fr) | 1985-03-01 |
DE3202622C2 (fr) | 1987-10-01 |
JPS6144845B2 (fr) | 1986-10-04 |
FR2498450A1 (fr) | 1982-07-30 |
JPS57144218A (en) | 1982-09-06 |
CH651208A5 (fr) | 1985-09-13 |
CA1174605A (fr) | 1984-09-18 |
AU549765B2 (en) | 1986-02-13 |
GB2091556B (en) | 1984-10-03 |
IL64798A0 (en) | 1982-03-31 |
AU7961382A (en) | 1982-08-05 |
NZ199472A (en) | 1984-05-31 |
US4308264A (en) | 1981-12-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
KB | Patent renewed | ||
KB | Patent renewed |