IL64534A0 - 3-(pyridylalkyl)indole derivatives,their preparation and pharmaceutical compositions containing them - Google Patents

3-(pyridylalkyl)indole derivatives,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL64534A0
IL64534A0 IL64534A IL6453481A IL64534A0 IL 64534 A0 IL64534 A0 IL 64534A0 IL 64534 A IL64534 A IL 64534A IL 6453481 A IL6453481 A IL 6453481A IL 64534 A0 IL64534 A0 IL 64534A0
Authority
IL
Israel
Prior art keywords
pyridylalkyl
preparation
pharmaceutical compositions
compositions containing
indole derivatives
Prior art date
Application number
IL64534A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of IL64534A0 publication Critical patent/IL64534A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IL64534A 1980-12-15 1981-12-14 3-(pyridylalkyl)indole derivatives,their preparation and pharmaceutical compositions containing them IL64534A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8040081 1980-12-15

Publications (1)

Publication Number Publication Date
IL64534A0 true IL64534A0 (en) 1982-03-31

Family

ID=10517993

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64534A IL64534A0 (en) 1980-12-15 1981-12-14 3-(pyridylalkyl)indole derivatives,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US4363912A (es)
EP (1) EP0054417B1 (es)
JP (1) JPS57181082A (es)
KR (1) KR830007552A (es)
AR (1) AR229110A1 (es)
AU (1) AU525296B2 (es)
CA (1) CA1143737A (es)
CS (1) CS228527B2 (es)
DD (1) DD202290A5 (es)
DE (1) DE3167879D1 (es)
DK (1) DK552581A (es)
ES (1) ES507960A0 (es)
FI (1) FI814003L (es)
GR (1) GR76355B (es)
IE (1) IE51949B1 (es)
IL (1) IL64534A0 (es)
NO (1) NO814264L (es)
PH (1) PH17576A (es)
PL (1) PL133634B1 (es)
PT (1) PT74123B (es)
YU (1) YU293481A (es)
ZA (1) ZA818665B (es)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS229934B2 (en) * 1981-07-07 1984-07-16 Pfizer Production method subst.indolylacryte acid derivative
US4460777A (en) * 1981-11-19 1984-07-17 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4478842A (en) * 1981-11-19 1984-10-23 Ciba-Geigy Corporation N-Substituted-2-pyridylindoles
US4536505A (en) * 1983-05-17 1985-08-20 Ciba-Geigy Corporation Certain N-(pyridyl) indoles
US4511573A (en) * 1983-05-17 1985-04-16 Ciba-Geigy Corporation 3-Substituted-2-(heteroaryl) indoles
GB8524157D0 (en) * 1984-10-19 1985-11-06 Ici America Inc Heterocyclic amides
US4609733A (en) * 1984-12-27 1986-09-02 Ciba-Geigy Corporation 3-keto-substituted-N-pyridylindoles
GB8609175D0 (en) * 1986-04-15 1986-05-21 Ici America Inc Heterocyclic carboxamides
MXPA02003122A (es) 1998-03-31 2004-04-21 Inst For Pharm Discovery Inc Acidos indolalcanoicos substituidos.
TNSN99224A1 (fr) 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
US20010044437A1 (en) * 2000-01-14 2001-11-22 Dale Robinson Methods for reducing uric acid levels
US7348351B2 (en) * 2002-12-10 2008-03-25 Wyeth Substituted 3-alkyl and 3-arylalkyl 1H-indol-1yl acetic acid derivatives as inhibitors of plasminogen activator inhibitor-1 (PAI-1)
GB0324763D0 (en) * 2003-10-23 2003-11-26 Oxagen Ltd Use of compounds in therapy
JP5270542B2 (ja) 2006-07-22 2013-08-21 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
BRPI0817397A2 (pt) * 2007-09-24 2015-04-07 Allergan Inc Compostos indol contendo grupos arila ou heteroarila com atividade biológica do receptor de esfingosina-1-fosfato (sip)
ES2442717T3 (es) 2008-01-18 2014-02-13 Atopix Therapeutics Limited Compuestos que tienen actividad antagonista de CRTH2
US7750027B2 (en) * 2008-01-18 2010-07-06 Oxagen Limited Compounds having CRTH2 antagonist activity
WO2009093029A1 (en) * 2008-01-22 2009-07-30 Oxagen Limited Compounds having crth2 antagonist activity
JP2011509990A (ja) * 2008-01-22 2011-03-31 オキサジェン リミテッド Ｃｒｔｈ２アンタゴニスト活性を有する化合物
GB201322273D0 (en) 2013-12-17 2014-01-29 Atopix Therapeutics Ltd Process
GB201407807D0 (en) * 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form
GB201407820D0 (en) 2014-05-02 2014-06-18 Atopix Therapeutics Ltd Polymorphic form

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5173M (es) * 1966-02-11 1967-06-19
FR7337M (es) * 1968-01-11 1969-10-13
GB2045244B (en) 1979-03-07 1983-01-26 Pfizer Ltd 3-1-(imidazolylalkyl) indoles
US4322533A (en) * 1980-03-17 1982-03-30 Lesher George Y 1H-Indole-2,3-dione derivatives

Also Published As

Publication number Publication date
JPS57181082A (en) 1982-11-08
AU7848881A (en) 1982-06-24
DK552581A (da) 1982-06-16
ES8308872A1 (es) 1983-10-01
PT74123B (en) 1983-12-19
DE3167879D1 (en) 1985-01-31
ZA818665B (en) 1982-10-27
AR229110A1 (es) 1983-06-15
PL133634B1 (en) 1985-06-29
EP0054417B1 (en) 1984-12-19
CS228527B2 (en) 1984-05-14
PL234253A1 (en) 1983-05-23
YU293481A (en) 1984-10-31
PT74123A (en) 1982-01-01
CA1143737A (en) 1983-03-29
PH17576A (en) 1984-10-01
DD202290A5 (de) 1983-09-07
IE812928L (en) 1982-06-15
KR830007552A (ko) 1983-10-21
ES507960A0 (es) 1983-10-01
AU525296B2 (en) 1982-10-28
EP0054417A1 (en) 1982-06-23
FI814003L (fi) 1982-06-16
NO814264L (no) 1982-06-16
GR76355B (es) 1984-08-06
IE51949B1 (en) 1987-04-29
US4363912A (en) 1982-12-14

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