IL64444A - 8-(3-substituted propyl)-3-phenyl-3-nortropanols,their preparation and pharmaceutical compositions containing them - Google Patents

8-(3-substituted propyl)-3-phenyl-3-nortropanols,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL64444A
IL64444A IL64444A IL6444481A IL64444A IL 64444 A IL64444 A IL 64444A IL 64444 A IL64444 A IL 64444A IL 6444481 A IL6444481 A IL 6444481A IL 64444 A IL64444 A IL 64444A
Authority
IL
Israel
Prior art keywords
nortropanols
phenyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL64444A
Other languages
English (en)
Other versions
IL64444A0 (en
Original Assignee
Boehringer Sohn Ingelheim
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Sohn Ingelheim filed Critical Boehringer Sohn Ingelheim
Publication of IL64444A0 publication Critical patent/IL64444A0/xx
Publication of IL64444A publication Critical patent/IL64444A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Endocrinology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
IL64444A 1980-12-04 1981-12-03 8-(3-substituted propyl)-3-phenyl-3-nortropanols,their preparation and pharmaceutical compositions containing them IL64444A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19803045688 DE3045688A1 (de) 1980-12-04 1980-12-04 Neue 8-arylalkyl-3-phenyl-3-nortropanole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
IL64444A0 IL64444A0 (en) 1982-03-31
IL64444A true IL64444A (en) 1985-02-28

Family

ID=6118272

Family Applications (1)

Application Number Title Priority Date Filing Date
IL64444A IL64444A (en) 1980-12-04 1981-12-03 8-(3-substituted propyl)-3-phenyl-3-nortropanols,their preparation and pharmaceutical compositions containing them

Country Status (22)

Country Link
US (1) US4393069A (ja)
EP (1) EP0053744A1 (ja)
JP (1) JPS57120588A (ja)
KR (1) KR830007571A (ja)
AR (1) AR227450A1 (ja)
AU (1) AU7822281A (ja)
CA (1) CA1143734A (ja)
CS (1) CS228526B2 (ja)
DE (1) DE3045688A1 (ja)
DK (1) DK536381A (ja)
ES (1) ES507667A0 (ja)
FI (1) FI813862L (ja)
GB (1) GB2088869B (ja)
GR (1) GR77312B (ja)
HU (1) HU185157B (ja)
IL (1) IL64444A (ja)
NO (1) NO814136L (ja)
NZ (1) NZ199162A (ja)
PH (1) PH17180A (ja)
PT (1) PT74080B (ja)
SU (1) SU1042617A3 (ja)
ZA (1) ZA818371B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA848275B (en) * 1983-12-28 1985-08-28 Degussa New piridine-2-ethers or pyridine-2-thioethers having a nitrogen-containing cycloaliphatic ring
SK232890A3 (en) * 1989-05-17 1998-11-04 Pfizer 2-piperidino and 2-pyrrolidino-1-alkanols derivatives and preparation method thereof
US5272160A (en) * 1989-05-17 1993-12-21 Pfizer Inc 2-piperidino-1-alkanol derivatives as antiischemic agents
ES2098248T3 (es) * 1989-05-17 1997-05-01 Pfizer Derivados de 2-piperidino-1-alcanoles como agentes antiisquemicos.
KR0163355B1 (ko) * 1990-05-10 1998-12-01 알렌 제이. 스피겔 신경보호성 인돌론 및 관련 유도체
US5340936A (en) * 1991-02-04 1994-08-23 Hoechst-Roussel Pharmaceuticals Inc. 8-azabicyclo[3.2.1]octane methanone and corresponding oximes
AU654554B2 (en) * 1991-04-18 1994-11-10 Pfizer Inc. Prodrug esters of phenolic 2-piperidino-1-alkanols
US5710168A (en) * 1991-10-23 1998-01-20 Pfizer Inc. 2-piperidino-1-alkanol derivatives as neuroprotective agents
US5527912A (en) * 1991-10-23 1996-06-18 Pfizer Inc. Intermediates for 2-piperidino-1-alkanol derivatives
US5436255A (en) * 1992-07-23 1995-07-25 Pfizer Inc. Method of treating diseases susceptable to treatment by blocking NMDA-receptors
WO1994004146A1 (en) * 1992-08-24 1994-03-03 President And Fellows Of Harvard College Cocaine analogues and their use as cocaine drug therapies and therapeutic and imaging agents for neurodegenerative disorders
US5770180A (en) * 1992-08-24 1998-06-23 Organix, Inc. Bridge-substituted tropanes for methods of imaging and therapy
US5498610A (en) * 1992-11-06 1996-03-12 Pfizer Inc. Neuroprotective indolone and related derivatives
NZ275151A (en) * 1994-01-31 1998-02-26 Pfizer 3r*4s*3-[4-(4-fluorophenyl)-4-hydroxy-piperidin-1-yl]-chroman-4 ,7-diol; isomers and salts
GB9510459D0 (en) 1995-05-24 1995-07-19 Zeneca Ltd Bicyclic amines
ES2218676T3 (es) * 1996-05-13 2004-11-16 Syngenta Limited Aminas biciclicas como insecticidas.
GB9623944D0 (en) * 1996-11-15 1997-01-08 Zeneca Ltd Bicyclic amine derivatives
GB9624114D0 (en) * 1996-11-20 1997-01-08 Zeneca Ltd Pesticidal bicyclic amine derivatives
GB9624611D0 (en) * 1996-11-26 1997-01-15 Zeneca Ltd Bicyclic amine compounds
WO1998025924A1 (en) 1996-11-26 1998-06-18 Zeneca Limited 8-azabicyclo[3.2.1]octane-, 8-azabicyclo[3.2.1]oct-6-ene-, 9-azabicyclo[3.3.1]nonane-, 9-aza-3-oxabicyclo[3.3.1]nonane- and 9-aza-3-thiabicyclo[3.3.1]nonane derivatives, their preparation and their use as insecticides
EP1361875A2 (en) * 2001-02-16 2003-11-19 Aventis Pharmaceuticals Inc. Novel heterocyclic amide derivatives and their use as dopamine d3 receptor ligands

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2921938A (en) * 1960-01-19 Certain
FR837273A (fr) 1938-04-29 1939-02-07 Blindage de guerre
GB644115A (en) * 1948-02-25 1950-10-04 Wellcome Found Improvements in and relating to the preparation of new derivatives of tropine
BE639446A (ja) * 1962-11-03
US3452029A (en) * 1966-11-21 1969-06-24 American Home Prod 3-alpha-phenylbenzyloxy - 8 - substituted nortropanes and their substitutents
US3657252A (en) * 1968-10-25 1972-04-18 Smith Kline French Lab 3-phenyl - 8-benzofuranylalkyl derivatives of nortropine and notropidine

Also Published As

Publication number Publication date
CA1143734A (en) 1983-03-29
EP0053744A1 (de) 1982-06-16
ZA818371B (en) 1983-08-31
PT74080A (de) 1982-01-01
KR830007571A (ko) 1983-10-21
JPS57120588A (en) 1982-07-27
NZ199162A (en) 1984-11-09
PH17180A (en) 1984-06-13
AU7822281A (en) 1982-06-10
FI813862L (fi) 1982-06-05
IL64444A0 (en) 1982-03-31
GB2088869B (en) 1984-07-18
SU1042617A3 (ru) 1983-09-15
US4393069A (en) 1983-07-12
PT74080B (de) 1983-12-19
ES8301980A1 (es) 1983-01-01
AR227450A1 (es) 1982-10-29
GB2088869A (en) 1982-06-16
HU185157B (en) 1984-12-28
GR77312B (ja) 1984-09-11
CS228526B2 (en) 1984-05-14
NO814136L (no) 1982-06-07
ES507667A0 (es) 1983-01-01
DK536381A (da) 1982-06-05
DE3045688A1 (de) 1982-07-08

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