IL61662A - 7-cyano-2,3,4,5-tetrahydro-1h-dibenz(2,3:6,7)oxepino(4,5-d)-azepines,their preparation and pharmaceutical compositions containing them - Google Patents

7-cyano-2,3,4,5-tetrahydro-1h-dibenz(2,3:6,7)oxepino(4,5-d)-azepines,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL61662A
IL61662A IL61662A IL6166280A IL61662A IL 61662 A IL61662 A IL 61662A IL 61662 A IL61662 A IL 61662A IL 6166280 A IL6166280 A IL 6166280A IL 61662 A IL61662 A IL 61662A
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
lower alkyl
oxepino
azepines
dibenz
Prior art date
Application number
IL61662A
Other languages
English (en)
Other versions
IL61662A0 (en
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IL61662A0 publication Critical patent/IL61662A0/xx
Publication of IL61662A publication Critical patent/IL61662A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
    • C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D313/14—[b,f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Water Treatment By Sorption (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Paper (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Plural Heterocyclic Compounds (AREA)
IL61662A 1979-12-10 1980-12-08 7-cyano-2,3,4,5-tetrahydro-1h-dibenz(2,3:6,7)oxepino(4,5-d)-azepines,their preparation and pharmaceutical compositions containing them IL61662A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1092879 1979-12-10

Publications (2)

Publication Number Publication Date
IL61662A0 IL61662A0 (en) 1981-01-30
IL61662A true IL61662A (en) 1983-11-30

Family

ID=4368292

Family Applications (1)

Application Number Title Priority Date Filing Date
IL61662A IL61662A (en) 1979-12-10 1980-12-08 7-cyano-2,3,4,5-tetrahydro-1h-dibenz(2,3:6,7)oxepino(4,5-d)-azepines,their preparation and pharmaceutical compositions containing them

Country Status (25)

Country Link
US (1) US4492691A (no)
EP (1) EP0030916B1 (no)
JP (1) JPS5692890A (no)
KR (2) KR850000610B1 (no)
AT (1) ATE9159T1 (no)
AU (1) AU546197B2 (no)
CA (1) CA1152987A (no)
CY (1) CY1354A (no)
DD (1) DD155617A5 (no)
DE (1) DE3069086D1 (no)
DK (1) DK157869C (no)
ES (1) ES497550A0 (no)
FI (1) FI76575C (no)
GB (1) GB2065120B (no)
GR (1) GR72505B (no)
HK (1) HK12887A (no)
HU (1) HU187283B (no)
IE (1) IE50583B1 (no)
IL (1) IL61662A (no)
KE (1) KE3683A (no)
MY (1) MY8700558A (no)
NO (1) NO154796C (no)
NZ (1) NZ195795A (no)
PT (1) PT72178B (no)
ZA (1) ZA807692B (no)

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3116283A (en) * 1963-12-31 Preparation of nitrogen heterocyclic
US3418339A (en) * 1966-04-04 1968-12-24 American Home Prod 10,11-epoxy-10,11-dihydro-5h-dibenzo[a,d] cycloheptene-5-carboxamides
CH507232A (de) * 1968-11-27 1971-05-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Thiepin- und Oxepinderivaten
CH505826A (de) * 1968-12-19 1971-04-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Azepinderivaten
US3749790A (en) * 1969-11-12 1973-07-31 Ciba Geigy Corp Derivatives of dibenzo(b,f)pyrrolo-(3,4-d)azepine in compositions and a method for producing a c.n.s. depressant effect
DK134555B (da) * 1969-11-20 1976-11-29 Ciba Geigy Ag Analogifremgangsmåde til fremstilling af azepinderivater eller additionssalte deraf med uorganiske eller organiske syrer.
US3777032A (en) * 1969-12-23 1973-12-04 Ciba Geigy Corp 2,3-dihydro-1h-thienobenozothiepino(4,5-c)pyrroles as cns-depressants
US3798237A (en) * 1969-12-23 1974-03-19 Ciba Geigy Corp Thiepin derivatives
US3682959A (en) * 1969-12-23 1972-08-08 Hans Blattner BENZOTHIEPINO{8 4,5-c{9 {0 PYRROLES
CH532038A (de) * 1970-05-25 1972-12-31 Ciba Geigy Ag Verfahren zur Herstellung von neuen Cycloheptenderivaten
US3859439A (en) * 1970-05-26 1975-01-07 Ciba Geigy Corp 2,3-dihydro-5 -trifluoromethyl-1h-dibenzo(2,3:6,7) thiepino (4,5-c) pyrroles as cns-depressants
CH531535A (de) * 1970-05-26 1972-12-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen Thiepinderivaten
NL178593C (nl) * 1974-01-31 1986-04-16 Akzo Nv Werkwijze ter bereiding van een farmaceutisch preparaat op basis van een tetracyclische verbinding en werkwijze voor de bereiding van de daarbij te gebruiken tetracyclische verbindingen.
US4112110A (en) * 1974-02-22 1978-09-05 Ciba-Geigy Corporation Oxygenated azatetracyclic compounds
CH592095A5 (no) * 1974-02-22 1977-10-14 Ciba Geigy Ag
SE405475B (sv) * 1974-03-06 1978-12-11 Du Pont Forfarande att framstella nya polycykliska derivat av pyrrolidin med lugnande och bedovande verkan
SE7501669L (sv) * 1974-04-05 1975-10-06 Ciba Geigy Ag Pyrrol-derivat och sett att framstella desamma.
CH624105A5 (en) * 1976-05-26 1981-07-15 Ciba Geigy Ag Process for the preparation of novel azatetracyclic compounds
NL7605526A (nl) * 1976-05-24 1977-11-28 Akzo Nv Nieuwe tetracyclische derivaten.

Also Published As

Publication number Publication date
DD155617A5 (de) 1982-06-23
ATE9159T1 (de) 1984-09-15
CA1152987A (en) 1983-08-30
GB2065120A (en) 1981-06-24
HU187283B (en) 1985-12-28
FI76575C (fi) 1988-11-10
MY8700558A (en) 1987-12-31
KR850000610B1 (ko) 1985-05-01
ES8200368A1 (es) 1981-11-01
AU6519680A (en) 1981-06-18
PT72178B (de) 1981-10-28
KE3683A (en) 1987-01-30
AU546197B2 (en) 1985-08-22
GR72505B (no) 1983-11-15
KR830004305A (ko) 1983-07-09
DK525180A (da) 1981-06-11
DK157869C (da) 1990-08-06
FI803806L (fi) 1981-06-11
NO154796B (no) 1986-09-15
CY1354A (en) 1987-04-24
DK157869B (da) 1990-02-26
ZA807692B (en) 1981-12-30
JPS5692890A (en) 1981-07-27
HUT34031A (en) 1985-01-28
GB2065120B (en) 1984-01-18
PT72178A (de) 1981-01-01
EP0030916B1 (de) 1984-08-29
EP0030916A1 (de) 1981-06-24
IL61662A0 (en) 1981-01-30
JPH0320396B2 (no) 1991-03-19
ES497550A0 (es) 1981-11-01
NO803712L (no) 1981-06-11
NO154796C (no) 1986-12-29
IE50583B1 (en) 1986-05-14
IE802575L (en) 1981-06-10
DE3069086D1 (de) 1984-10-04
HK12887A (en) 1987-02-20
US4492691A (en) 1985-01-08
NZ195795A (en) 1984-11-09
FI76575B (fi) 1988-07-29

Similar Documents

Publication Publication Date Title
PT80661B (en) Process for preparing substituted imidazopyridines
EP0103833A3 (en) Diazabicyclo(3.3.1)nonanes
IL69036A (en) Alpha-alkyl undecapentaenoic acids,pharmaceutical compositions containing the same and processes for the preparation thereof
IL61662A (en) 7-cyano-2,3,4,5-tetrahydro-1h-dibenz(2,3:6,7)oxepino(4,5-d)-azepines,their preparation and pharmaceutical compositions containing them
DE3069173D1 (en) Substituted phenylamino-2-imidazoline-2 derivatives, their acid addition salts, medicaments containing them and process for their preparation
ES8304571A1 (es) "procedimiento para la preparacion de nuevas 1,4,9,10-tetrahidro-pirazolo (4,3-e)pirido (3,2-b) (1,4)diazepin-10-onas".
DE3161553D1 (en) Thiazolo(3,2-a)pyrimidine derivatives, their preparation and pharmaceutical compositions containing them
IL59052A (en) Hexahydro-1,4-oxazepine derivatives,their preparation and pharmaceutical compositions containing them
ATE5193T1 (de) Triazolo (4,3-a)pyridin-3-(2h)-one, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
DE3162691D1 (en) 4h-benzo(4,5)cyclohepta(1,2-b)furan derivatives, process for their preparation and their use as medicines
DE3365933D1 (en) Substituted thienobenzodiazepinones, process for their preparation and medicines containing these compounds
ZA807790B (en) 2-phenylamino-imidazolines-(2),compositions thereof and process for the preparation thereof
HUT50833A (en) Process for producing indolo/3,2-1-de/ /1,4/-oxazino/2,3,4-ij/ /1,5/-naphthyridine derivatives
ES484664A1 (es) Un procedimiento para la preparacion de derivados octahidro-1h-benzo 4,5 furo,3,2-e isoquinolina.
HUT60495A (en) Process for producing ergoline derivatives and pharmaceutical compositions comprising such compounds